How To Help Prevent Alzheimer’s: Mayo Clinic’s Latest Research With Dr. Jonathan Graff-Radford Optimal Aging podcast

Content provided by Jay Croft. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Jay Croft or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

Optimal Aging »
How to Help Prevent Alzheimer’s: Mayo Clinic’s Latest Research with Dr. Jonathan Graff-Radford

4d ago 33:50

MP3•Episode home

In this episode of the Optimal Aging Podcast, Jay Croft speaks with Dr. Jonathan Graff-Radford, a Mayo Clinic neurologist and co-author of the new edition of the Mayo Clinic Guide to Alzheimer’s and Other Dementias. They discuss how Alzheimer’s disease begins 20 years before symptoms appear, what can be done to prevent or delay it, and what health and fitness professionals working with people over 50 need to know now.

Dr. Radford shares powerful new insights on early detection tools, lifestyle factors like exercise and hearing loss, and how fitness protocols can support cognitive health. You'll also hear how dual-tasking workouts, VO2 max, and neuroplasticity play a role in long-term brain health.

If you serve older adults in health, fitness, or wellness, this is a must-listen.

👤 Guest: Dr. Jonathan Graff-Radford

Bio:
Dr. Jonathan Graff-Radford is a neurologist at the Mayo Clinic and co-author of Mayo Clinic on Alzheimer’s Disease and Other Dementias. His research focuses on early detection, prevention, and treatment of neurodegenerative diseases.

Resources & Links:

Mayo Clinic Guide to Alzheimer’s: https://mcpress.mayoclinic.org/product/mayo-clinic-on-alzheimers-and-other-dementias/
Mayo Clinic Brain Health Tips: https://www.mayoclinic.org/healthy-lifestyle/healthy-aging/in-depth/brain-health-tips/art-20555198
Mayo Clinic Alzheimer’s Disease Resources: https://www.mayo.edu/research/centers-programs/alzheimers-disease-research-center/research-activities/mayo-clinic-study-aging/patients-families/resources

🧠 Topics Covered

What Is Alzheimer’s Really?

Difference between Alzheimer’s and general dementia
Amyloid and tau proteins in the brain

Why Prevention Starts Now

Alzheimer’s can start 20 years before symptoms
40–45% of dementia may be preventable

Lifestyle Factors That Matter

Exercise, diet, sleep, stress, and social connection
Hearing loss as a major (and treatable) risk factor

How Exercise Affects the Brain

Growing the hippocampus with aerobic exercise
VO2 max and brain resilience studies

The Role of Neuroplasticity

How the brain adapts and rewires itself
Dual-tasking in fitness for cognitive engagement

New Tools and Treatments

Blood tests with 90% accuracy
Two new FDA-approved drugs slow progression
Early detection through the Ahead & Trailblazer studies

📱 Follow Jay Croft
Instagram: https://www.instagram.com/primefitcontent
LinkedIn: https://www.linkedin.com/in/croftjay
🌐 Website: https://primefitcontent.com
📬 Contact: [email protected]
👍 Like this episode? Share it with a friend or leave a review on Apple Podcasts!

Chapters

1. Alzheimer's Starts 20 Years Before Symptoms (00:00:00)

2. Dementia vs. Alzheimer's Explained (00:01:03)

3. New Research on Prevention (00:05:15)

4. Exercise Grows Brain's Memory Center (00:09:07)

5. Neurogenesis and Neuroplasticity Explained (00:15:47)

6. Early Detection and New Treatments (00:21:46)

7. Prevention Strategies and Takeaways (00:28:08)

8. Supporting Brain Health (00:33:39)

174 episodes

#Fitness #Jay Croft #Active Aging #Baby Boomers #Exercise #Physical Fitness #Wellbeing After 50 #Content Marketing #Alternative Health #Business #Marketing #Fitness At 50 #Function Fitness