Catching Dementia Early The Longevity Podcast: Optimizing HealthSpan & MindSpan podcast

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The Longevity Podcast: Optimizing HealthSpan & MindSpan »
Catching Dementia Early

11h ago 12:03

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A silent crisis is unfolding in plain sight: mild cognitive impairment is missed at staggering rates, even as new Alzheimer’s treatments work best in the earliest stages. We sit down with the data and the day-to-day reality of primary care to ask a harder question—how do we turn belief and capability into action under relentless time pressure?
Our journey follows the Davos Alzheimer’s Collaborative through a global field test spanning Brazil, Jamaica, Mexico, Scotland, and two U.S. sites. Teams rolled out digital cognitive assessments and, where possible, blood-based biomarkers—then adapted to local constraints to make early detection feasible. In Jamaica, a lack of Alzheimer’s biomarkers led to subsidized labs and ECGs for positive screens, catching reversible causes like thyroid issues and vitamin deficiencies. That’s implementation science in motion: tailor the tools to the clinic, not the clinic to the tools.
The results are revealing. Clinicians already valued early diagnosis, but confidence jumped nearly 10% after the rollout, especially where digital assessments and biomarkers were used together. And yet, engagement—the willingness to weave screening into daily practice—barely moved. That paradox reframes the problem. The bottleneck isn’t knowledge or motivation; it’s workflow. We explore the system fixes that actually unlock adoption: pre-visit screening, delegation to support staff, EHR order sets and templates, clear next steps after a positive screen, and protected time. We also point to a free Early Detection Blueprint built from these lessons to help leaders design pathways that fit real clinics.
If you care about aging, primary care, Alzheimer’s research, or practical health innovation, this conversation offers a grounded, hopeful path forward. Subscribe, share with a colleague who shapes clinical workflows, and leave a review with one change you’d make to boost early detection in your setting.

This podcast is created by Ai for educational and entertainment purposes only and does not constitute professional medical or health advice. Please talk to your healthcare team for medical advice.

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Chapters

1. The Global Dementia Surge (00:00:00)

2. The Early Detection Gap (00:00:37)

3. Why Timing Now Matters (00:01:45)

4. Barriers In Primary Care (00:02:11)

5. Implementation Science Approach (00:02:50)

6. Global Field Test Overview (00:03:21)

7. Tools: Digital Tests And Blood Biomarkers (00:03:46)

8. Local Adaptation In Practice (00:04:23)

9. Measuring Clinician Readiness (00:05:02)

10. Attitude Confidence Engagement Explained (00:05:29)

11. Survey Limits And Caveats (00:06:09)

12. Results Headline Improvement (00:06:33)

13. Confidence Jumps Across Sites (00:07:03)

14. The Engagement Paradox (00:07:50)

15. System Design Over Tools (00:08:35)

16. PCP Findings And Blueprint (00:10:00)

17. The Challenge Ahead (00:11:00)

90 episodes

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