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Patient Empowerment Program: A Rare Disease Podcast

n-Lorem Foundation (Dr. Stan Crooke, Amy Williford, Kim Butler, Andrew Serrano, Jon Magnuson, and Kira Dineen)

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Join the nano-rare disease community! Interviews features leading physicians, scientists, biotech experts, and patient advocates. Lessons teach core concepts about drugs. Our host Dr. Crooke has led the creation of antisense technology and his foundation, n-Lorem, is using this powerful technology to discover, develop, and provide personalized experimental antisense oligonucleotide medicines to nano-rare patients for free, for life. n-Lorem is a non-profit organization established to apply t ...
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Welcome to CFO 4.0, where we explore the dynamic landscape of Financial Leadership in the era of Technology 4.0. I'm your host, Hannah Munro, Managing Director of itas, a pioneering Financial Transformation consultancy. In this podcast series, we unravel the intricate connection between cutting-edge technologies and the financial domain. It's more than just adopting tools; it's about cultivating the skills necessary to navigate and spearhead the transformative journey within Finance. CFO 4.0 ...
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SossTalk

SossTalk

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The SossTalk Podcast! A podcast where at any episode can be about so many different things. It's mainly a boxing show. But boxing isn't the only talking point. Pro wrestling comes in to play. Big news in the NFL and NBA! Top news period! This is also a podcast that brings many guests to debate topics and many more! If you come and listen to Sosstalk, I'm sure we can get you and many others on board with us. Hit that play button!!!!
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As the 2025 Nano-rare Patient Colloquium approaches, we welcome back Transmitter Features Editor Brady Huggett to guest-host this episode of the Patient Empowerment Program podcast. Brady sits down with n-Lorem founder and CEO, Dr. Stan Crooke, to reflect onto reflect on the strides made over the past year—insights that will help shape the discussi…
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Send us your thoughts In this episode of the CFO 4.0 Podcast, host Hannah Munro sits down with Charlotte Crowley, CFO at Altano, to explore her journey through finance leadership, acquisitions, and the challenges of integrating companies without losing their culture. Charlotte shares her unique career path — from starting in advertising and PR to w…
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Send us your thoughts In this special solo episode of the CFO 4.0 Podcast, host Hannah Munro takes on a personal challenge what she would do with 90 days to transform finance. Drawing on her experience working with finance teams, Hannah breaks the journey into three clear phases: stabilisation, automation and efficiency, and forward looking acceler…
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The ‘Hero of n-Lorem’ Award is a recognition given to an individual volunteer or organization that has made substantial contributions to n-Lorem and our nano-rare patients. This honor recognizes our ‘unsung heroes’, those who have gone the extra mile, taken time away from their schedules and families and leveraged their expertise and contacts to su…
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Send us your thoughts In this episode of CFO 4.0, host Hannah Munro is joined by returning guest Susana Serrano-Davey, seasoned finance leader and leadership mentor, to explore the people side of change. Together, they discuss how leaders can support teams through uncertainty and build a culture of resilience. In this episode, you’ll learn: Why hon…
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Send us your thoughts In this episode of Financial Transformation Live, host Hannah Munro shares what it really takes to deliver a successful finance system implementation. From preparing your team to managing risks and ensuring a smooth go-live, Hannah offers practical insights and lessons learned from real-world projects. You’ll learn: How to pre…
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Rescue 7 is dedicated to serving the most vulnerable patient communities with care, compassion, and critical support. Inspired by the traditions of Fire Departments, Police Departments, and Military service worldwide, their programs go beyond emergency response. From patient transportation to sibling support initiatives, as well as emergency disast…
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Send us your thoughts In this episode of CFO 4.0, host Hannah Munro talks with Tariq Munir, Managing Partner at Finspyr and author of Reimagine Finance, about how CFOs and finance leaders can lead successful transformation in the age of AI. In this episode, you’ll learn: Why transformation should be embedded in everyday finance work, not treated as…
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Send us your thoughts In this episode of CFO 4.0, host Hannah Munro continues the Private Equity series with Ian Pugh, CFO at Precise TV. Ian shares his journey into private equity and reveals the realities of leading finance in a fast-paced, investor-backed business. In this episode, you’ll discover: The importance of trust with investors — and ho…
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Sarah and Ryan Marta, proud parents of three girls from Central Texas, began noticing that their middle daughter, Kinsley, was slow to reach mobility milestones in her early years. During a visit to a friend’s house, concerns about her vision were raised, prompting a check-up. What began as a single hospital visit quickly turned into many. An MRI r…
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Send us your thoughts In this episode of CFO 4.0, Hannah Munro chats with Andrew Brummer, CFO at Distributed, about the realities of finance leadership in early-stage and high-growth businesses. From managing cashflow crises to building future-ready finance teams, Andrew shares lessons from his unconventional journey and startup experience. Topics …
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Send us your thoughts In this Transformation Troubleshooter edition of Financial Transformation Live, hosts Hannah Munro and Neil Lynchehaun tackle real-world finance transformation challenges shared by listeners. From project overload to spreadsheet sprawl, they offer practical strategies to help finance leaders navigate complexity with confidence…
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Emerging observations from our work at n-Lorem suggest that not all developmental delays are permanent. In the absence of structural damage—such as microcephaly, congenital deformities of the skull or bones, or organ malformations—there appears to be potential for improvement in movement disorders, cognition, autistic features, and more. These insi…
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Send us your thoughts In this episode of CFO 4.0, host Hannah Munro speaks with Andy Mellor, Fractional CFO at Summit 17 Ltd, about navigating M&A, preparing for financial events, and leading finance teams through high-growth environments. Key topics covered: Andy’s career journey and transition into fractional CFO work Structuring finance teams to…
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Send us your thoughts In this episode of the CFO 4.0 Podcast, host Hannah Munro is joined by experienced CFO and executive coach Jeremy Earnshaw to explore one of the most critical – and often overlooked – phases of the CFO journey: the 60–90 day window. In this episode, we cover: How to assess and ensure data integrity before making strategic deci…
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At n-Lorem, every investment decision carries real weight by directly affecting the nano-rare patients we serve. We think very deeply about each decision of how to invest the limited and precious dollars that we have. But what about investing in basic research to advance antisense oligonucleotide (ASO) technology for the future? Certainly, most of …
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Send us your thoughts In this episode of CFO 4.0, Hannah Munro is joined by Matt Topham, Director of Practical CFO, to explore what makes a modern CFO truly effective—from KPIs to strategic decision-making. Key topics covered: Matt’s unconventional journey to CFO The realities of working as a fractional CFO and identifying clients ready for change …
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Send us your thoughts In this month's Finance Transformation Live host Hannah Munro explores how finance leaders can design scalable, resilient systems that adapt to change and support long-term growth. Key topics covered: The four pillars of future-proof finance architecture: data, APIs, expandability, and maintenance Why multi-dimensional data st…
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The Data Safety Monitoring Board (DSMB) is composed of distinguished, independent experts in antisense oligonucleotide (ASO) technology, clinical trial design and evaluation, and drug development. Many are also dedicated clinicians who care for patients with rare diseases. This board provides unbiased safety oversight by reviewing accumulated data …
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Send us your thoughts In this insightful episode of the CFO 4.0 Podcast, host Hannah Munro is joined by Richard Sanders, Founder and Managing Partner at Sullivan Street Partners, for a no-holds-barred session of myth-busting in the world of private equity. This episode offers practical wisdom, experienced insights, and a refreshingly candid take on…
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Send us your thoughts In this episode of CFO 4.0, host Hannah Munro speaks with Karl Lloyd, fractional CFO and founder of Lloyd Consulting Limited, about his transition from full-time finance roles to a portfolio CFO career. Karl shares practical insights from working across sectors like e-commerce, SaaS, and travel, and reflects on the realities o…
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Connor Gooley is the first patient ever treated with an ASO for TUBB4A-Related Leukodystrophy, a condition that severely disrupts his nervous system, slows nerve impulses, and impairs his fine motor skills. As a result, Connor cannot speak, walk, sit up on his own, or chew well. Still, he manages to army crawl, propel himself in his wheelchair, and…
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Send us your thoughts In this episode of CFO 4.0, host Hannah Munro chats with Karla Smith, CFO at Ogilvy UK, about her unique path to CFO and how finance operates at the heart of a creative, people-driven organisation. Key topics covered include: Karla’s career journey from audit trainee to CFO How to succeed in senior finance roles with flexible …
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Send us your thoughts In this episode of CFO 4.0, Neil Lynchehaun unpacks the Records-to-Report (R2R) maturity model and shares hard-earned insights from decades in finance transformation. He challenges traditional finance thinking and explores how finance teams can shift from compliance to strategic enablement. What’s covered in this episode: Why …
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Induced pluripotent stem cells (iPSCs) are a groundbreaking, and mind-blowing, scientific advancement—one of many that help make it possible for n-Lorem to do what we do. In short, typical skin cells (such as fibroblasts) are taken from an individual and reprogrammed using specific factors to become iPSCs. These iPSCs are then redifferentiated into…
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Send us your thoughts In this episode of CFO 4.0, we dive into the critical 30 to 60 day phase of a CFO's journey with returning guest Jeremy Earnshaw, Founding Director of Clarendon and experienced CFO. Building on our previous conversation about the first 30 days, this episode explores how new CFOs can transition from learning to leading. 🔍 Key T…
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Send us your thoughts In this episode of CFO 4.0, host Hannah Munro speaks with David Wood, Chair of London Futurists, about the accelerating pace of AI and its profound implications for business, society, and the future of work. Together, they explore the near-term possibilities and longer-term consequences of artificial intelligence—from transfor…
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What Are Chemicals? | How Drugs Work in the Body | Understanding Homeostasis We’re all made of chemicals—but what exactly is a chemical? In this video, we break down the basics: chemicals are forms of matter that exist as solids, liquids, or gases. Inside living organisms, these chemicals create complex networks that keep us alive and balanced—a pr…
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Send us your thoughts In this episode of CFO 4.0, host Hannah Munro is joined once again by Rob Jackson, now Senior Associate Consultant at Protiviti UK. Rob reflects on his journey from leading finance operations at Sage to spearheading transformation projects in private equity-backed businesses. Together, they unpack what it really takes to deliv…
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Send us your thoughts In this episode of CFO 4.0 – The PE CFO Series, Hannah Munro is joined once again by Richard Sanders, Founder and Managing Partner at Sullivan Street Partners. Together, they dive into “The Good, The Bad, and The Ugly” of private equity—an honest conversation unpacking what it’s really like behind the boardroom doors of a PE-b…
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What makes antisense oligonucleotides (ASOs) so special? Let’s first understand what an oligonucleotide is. An oligonucleotide is a short strand of synthetic DNA or RNA (a nucleic-acid chain), usually consisting of up to approximately 20 nucleotides long—designed to bind with specific sequences in the body. At n-Lorem, our ASO technology is built o…
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Send us your thoughts In this episode of Financial Transformation Live, Neil Lynchehaun, Head of Transformation and Delivery at itas, takes you through a practical, experience-driven guide to understanding and improving the Purchase-to-Pay (P2P) process. You’ll discover: Why we use maturity models and how they can inspire achievable steps forward. …
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Send us your thoughts This episode kicks off our new CFO 4.0 series exploring the first 100 days in a CFO role. Host Hannah Munro is joined by experienced CFO and coach Jeremy Earnshaw, who shares practical, battle-tested guidance on navigating the critical first 30 days in a new CFO position. Key topics covered Making a strong first impression and…
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Connor Dalby was born with an SCN2A ion channel mutation causing severe epilepsy and eventually leading to hospice care at an early age. It was a chance hallway conversation between Connor’s mom and Dr. Stan Crooke at a conference that sparked the idea for what would become n-Lorem. In a full-circle moment, Connor went on to become the very first p…
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Send us your thoughts In this inspiring and practical episode of CFO 4.0, host Hannah Munro welcomes back Susana Serrano-Davey—career mentor, leadership trainer, and author of the newly released Confidence is Overrated. Drawing from her journey from CFO to mentor and author, Susana shares powerful insights on how senior finance leaders can develop …
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Send us your thoughts In this episode of CFO 4.0, Hannah Munro speaks with Gemma Doran, CFO at Savea Technology Ltd, about the realities of leading finance in high-growth SMEs. From her unexpected start in journalism to managing multi-million-pound fundraises, Gemma reflects on what it takes to thrive as a CFO in fast-moving environments, how to ba…
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For n-Lorem's Chief Operating Officer, Sarah Glass, the mission of n-Lorem is deeply personal. Her son Ethan was diagnosed with a nano-rare mutation, a journey that has shaped her commitment to the cause. A geneticist by training, Sarah joined n-Lorem to help lead and guide the organization in its efforts to offer hope and potential help through tr…
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Send us your thoughts In this episode of Financial Transformation Live, Hannah Munro dives into the critical steps for effective process mapping and how it can drive successful financial transformation. Discover practical insights on simplifying complexity and ensuring your processes are future-ready. Key takeaways include: The importance of involv…
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Send us your thoughts In this episode of CFO 4.0, host Hannah Munro sits down with Richard Sanders, Founder and Managing Partner of Sullivan Street Partners, to explore how CFOs can navigate their first 100 days in Private Equity, set the right priorities, manage investor expectations, and lay the groundwork for long-term success. Key topics covere…
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Our bodies are like bustling cities of cells, always chatting and working together. They don’t just send long-distance messages to organs—they also gossip locally, getting nearby cells to spring into action. Juxtacrine communication is like a handshake between cells—they have to be up close and personal to pass the message along! Unlike long-distan…
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Send us your thoughts In this episode of CFO 4.0, Hannah Munro sits down with Peter Morgan, CEO of Deep Learning Partnership and head tutor at Oxford University’s Saïd Business School, to explore the rapid rise of AI and its impact on finance. Key discussion points: Why advancements in AI have accelerated exponentially and what’s driving the change…
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Send us your thoughts In this fourth instalment of the Mastering M&A series, host Hannah Munro is joined by Jeremy Earnshaw, Founding Director of Clarendon and experienced CFO, to explore the journey from CFO to Non-Executive Director (NED). Whether you're considering your first NED role or want to understand the challenges and opportunities that c…
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How do cells communicate with each other? With trillions of cells in the human body, seamless collaboration is essential within this intricate cellular society. Cells work together to form organs, and when one organ needs another to perform a task, they send signals across distances—much like picking up the phone and calling someone. Organ Hotline …
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Send us your thoughts In this episode of Financial Transformation Live Hannah Munro explores how finance leaders can step up and take a more strategic role in driving change and process improvement across their organisations. With AI and automation set to reshape finance, CFOs and finance teams must shift their focus beyond transactional tasks and …
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Send us your thoughts In this episode of the CFO 4.0 Podcast, host Hannah Munro sits down with Phil Moses, CFO at Octavius, to discuss his fascinating career journey from working in PLCs to Private Equity-backed businesses. With experience spanning insurance, telecoms, infrastructure, and construction, Phil shares his lessons on managing investors,…
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Rosie was the first of three HNRNPH2 patients to receive treatment with an n-Lorem ASO, helping to pave the way for others. Her parents, Nicole and Bobby, share their daughter's journey and how they have adapted as a family to meet her unique needs. As a pediatrician, Nicole understands the complexities of medical care, yet she acknowledges that ev…
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Send us your thoughts In this episode of CFO 4.0, host Hannah Munro welcomes back Private Equity expert Richard Sanders, Founder and Managing Partner of Sullivan Street Partners, for the next episode of The Private Equity CFO. Together, they break down the key considerations for businesses looking to secure Private Equity investment, the challenges…
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Send us your thoughts In this episode of CFO 4.0, Hannah Munro speaks with Stuart Mellis, CFO of Optalysis, about his journey to CFO, the challenges of scaling deep tech startups, and navigating fundraising, investor relations, and financial planning in an emerging market. Key topics covered: Private equity vs venture capital – key differences in e…
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Sloane was born with a KIF1A mutation and is a special case at n-Lorem—she was the first patient to receive a medicine originally designed for someone else. Her mother, Megan, and grandfather, Tom, join the Patient Empowerment Program to share her journey and provide an update on how she’s doing six months after treatment. On This Episode We Discus…
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Send us your thoughts In this third instalment of the Mastering M&A series, Hannah Munro is joined by Jeremy Earnshaw, Founding Director of Clarendon and experienced CFO, to delve into the complexities of business disposals. Key topics discussed: The difference between being sought out by a buyer vs proactively seeking a sale. Essential preparation…
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