Drs. Spencer and Karl Nadolsky talk about nutrition, medicine, and fitness through the lens of two physicians who lift weights. Both doctors are former NCAA division 1 wrestlers who have gone into medicine. Dr. Spencer Nadolsky is a board certified family physician specialized in obesity medicine and lipidology. Dr. Karl Nadolsky is a board certified endocrinologist also specialized in obesity medicine.
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Docs Who Lift Podcasts
The power of conversation is lost. There’s nothing better than sitting down for a natter with your mate and putting the world to rights. Well in this podcast, that’s exactly what Amanda Thebe will be doing. She really gets to know her guests, warts and all! She is a force of nature for women in midlife who want real-life honest conversations about the challenges, the thrills and the opportunities that await us in midlife and beyond. In each episode Amanda leaves no stone unturned, getting de ...
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Women’s Fitness Needs Debate: Dr. Stacy Sims vs. Dr. Lauren Colenso-Semple
1:07:13
1:07:13
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1:07:13We covered: Fasted training Protein timing and many more fitness topics! Hear Dr. Lauren Colenso-Semple and Dr. Stacy Sims discuss outcomes versus mechanisms and much more Tap Here for Dr Stacy Sims References Tap Here for Dr. Colenso-Semples References Dr. LCS Instagram Dr. SS InstagramBy Docs Who Lift
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Do You Really Lose Muscle on Semaglutide or Tirzepatide?
33:50
33:50
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33:50Takeaways The podcast features Dr. Grant Tinsley, a body composition expert. The discussion revolves around a case series on body composition effects. GLP-1 receptor agonists are a focus of the research. The importance of resistance training in weight loss is emphasized. Patient case studies provide insights into individual experiences. The first p…
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Predatory Lab Testing: What They’re Not Telling You
49:50
49:50
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49:50Takeaways Direct-to-consumer lab testing is on the rise, with significant marketing efforts behind it. Many patients feel brushed off by traditional healthcare providers, leading them to seek alternative testing options. Communication between patients and healthcare providers is often inadequate, contributing to misunderstandings about health. Over…
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In this episode of the Dr. Lift podcast, hosts Dr. Spencer Nadolsky and Dr. Karl discuss the recent changes in obesity medication coverage, particularly focusing on the CVS Caremark decision to drop ZEPBound from their formulary in favor of Wegovi. They explore the implications of this decision for patients and providers, the role of pharmacy benef…
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More Than Weight Loss? GLP-1s and Cardiovascular Risk
11:16
11:16
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11:16In this episode of the Dr. Lift podcast, hosts Dr. Spencer Nadolsky and Dr. Karl discuss the Surpass CVOT trial, which evaluates the cardiovascular outcomes of Monjaro compared to Dulaglutide (Trulicity). They delve into the significance of the trial, the implications of the results, and the potential benefits of Monjaro for patients with type 2 di…
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Semaglutide vs. Tirzepatide: Are We Closing the Gap?
41:34
41:34
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41:34How the STEP-UP trial came to life, and what made the 7.2mg dose possible What the data actually says about weight loss and side effects at higher doses Why trial design, pharmacokinetics, and estimands matter more than you think What’s coming next in obesity meds: duals, triples, and even antagonists The real talk on intermittent fasting, access i…
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Takeaways The study examines the overlap between clinical and anthropometric obesity. Anthropometric measures include waist circumference, waist-to-hip ratio, and BMI. Challenges exist in applying the Lancet Commission's definitions in clinical practice. Metabolically healthy obesity is a debated topic in obesity research. The study highlights the …
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Learn what age-related macular degeneration (AMD) is What causes AMD The types of AMD The update on NAION - listen to last year's podcast all about it Why we aren't too concerned Click here to join Dr. Spencer's online clinic Vineyard Click to read the JAMA AMD article Click to read the Ophthalmology journal AMD article…
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Menopausal hormonal therapy should not be a blanket recommendation for everyone going through menopause Weight management in women is influenced by hormonal changes throughout life stages. Retrospective analyses can provide insights but have limitations. The wellness industry often oversimplifies complex medical issues. Hormonal replacement therapy…
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The Science of Myostatin inhibitors, GLP-1 meds and Muscle Mass
28:28
28:28
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28:28Dr. Grant Tinsley joins the discussion as the body composition expert. Myostatin is a key regulator of muscle growth. Wendy Whippete the most jacked muscled up dog The concern of GLP-1 receptor agonists and muscle mass loss. Overview of Courage trial looking at semaglutide and trevogrumab and lean mass loss Upcoming Believe trial coming out (bimagr…
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Current State of Nutrition Research and MAHA
56:22
56:22
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56:22Takeaways: The MAHA report aims to address public health issues but lacks actionable policies. Historical context is crucial for understanding current dietary guidelines. Funding for nutrition research has been inadequate, impacting the quality of data. Public perception of nutrition often outpaces scientific evidence. The evolution of dietary guid…
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Click to read Joy Prescriptions Drs. Karl and Spencer talk to Dr. Tiffany Moon all about Joy Prescriptions. Learn how to stop chasing perfection and embrace connection. 00:00Introduction to Dr. Tiffany Moon 02:02Journey to Reality TV: The Real Housewives of Dallas 05:58Life After Reality TV: Finding Joy and Purpose 09:59The Joy Prescription: A New …
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Tirzepatide is more effective for weight loss than semaglutide. Cost-effectiveness is crucial in prescribing weight loss medications. Patients with severe obesity should receive more expensive medications for better outcomes. Both medications show significant benefits for obesity-related conditions. Long-term studies indicate sustained weight loss …
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Semaglutide for metabolic dysfunction associated steatotic liver disease (MASH).
22:20
22:20
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22:20Takeaways MASH is a significant obesity-related complication. Semaglutide shows promise in treating MASH. Weight loss is crucial for improving liver health. Bariatric surgery remains the most effective treatment. The Essence trial indicates a 63% resolution of NASH. New medications are being developed for obesity treatment. Early intervention is ke…
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Drs. Karl and Spencer chat with return guest Dr. Lauren Semple about creatine, protein, cortisol, fasting exercise, and training in women. Follow Dr. Lauren's instagram Join Dr. Spencer's online clinicBy Docs Who Lift
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Drs. Karl and Spencer discuss a new study looking at tirzepatide and metabolic rate. They also discuss a patient case of tirzepatide induced anhedonia. Here is the tirzepatide study If interested in joining Dr. Spencer's clinic Vineyard - Click HereBy Docs Who Lift
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Drs. Karl and Spencer discuss the claim that GLP-1 meds cause more fat cells. Learn about if and how GLP-1 meds increase fat cells and what that means along with other claims about these medicine. Join Dr. Spencer's online clinic that specializes in GLP-1 medicinesBy Docs Who Lift
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Drs. Karl and Spencer talk to Dr. Kenneth Qiu all about direct medical care - the future of medicine. Learn about how bypassing insurance and creating a relationship directly with a doctor can improve your health and save money in the long run. Follow Dr. Qiu on Linked in See Dr. Spencer's direct care model with Vineyard…
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Tirzepatide and Muscle Loss with Dr. Grant Tinsley
27:44
27:44
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27:44Drs. Karl and Spencer discuss with Dr. Grant Tinsley all about the new analysis of how much "lean mass" is lost with tirzepatide, the most powerful medicine available for weight loss. Learn: The difference between fat free mass and lean mass and lean soft tissue and muscle. If GLP-1 medicines cause muscle loss specifically How to minimize muscle lo…
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Drs. Karl and Spencer discuss how bad the Hims and Hers ad was. From an outside perspective, the ad may have seemed good. But when you dig deeper, it was actually really bad. Listen to learn. Join Dr. Spencer's new online clinic - Vineyard.By Docs Who Lift
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Drs. Karl and Spencer chat with NMN and NAD expert Dr. Charles Brenner all about these supposed longevity supplements. Learn about NAD metabolism Whether it's worth supplementing or not with NAD or NMN Follow Dr. Brenner on TwitterBy Docs Who Lift
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The 60 Minutes Obesity Doctor - Dr. Fatima Cody Stanford
45:33
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45:33Drs. Karl and Spencer chat with Dr. Fatima Cody Stanford all about obesity, genetics, and her appearance on 60 minutes. Does Dr. Sanford believe lifestyle doesn't matter for obesity? Find out by listening! Watch Dr. Stanford's 60 minute clip Join Dr. Spencer's Obesity ClinicBy Docs Who Lift
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New Obesity Definition and Higher Wegovy Dose
29:12
29:12
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29:12Drs. Karl and Spencer chat about the new Lancet Commission's report on Clinical Obesity along with the new study on high dosed Wegovy. Learn: How 7.2 mg of Wegovy (semaglutide) compares to 2.4 mg What the proposed definitions of clinical and preclinical obesity are Click here to join Dr. Spencer's new online clinic…
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Drs. Karl and Spencer chat with Dr. Sowa about her book The Ozempic Revolution. Learn: Why she wrote the book. The top 3 things to know when starting a GLP-1 medicine. Also hear the top criticism from Drs. Karl and Spencer. You will laugh. Click here to get the book If you're on a GLP-1 currently and want to switch to Dr. Spencer's new clinic, Clic…
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Microdosing GLP-1 and Cagrisema headlines
40:20
40:20
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40:20Drs. Karl and Spencer discuss the concept of "microdosing" GLP-1 receptor agonists along with talk about the new top line results from REDEFINE which studied the new drug CagriSema.By Docs Who Lift
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Changing your workouts based on your menstrual cycle
30:07
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30:07Drs. Karl and Spencer chat with Dr. Lauren Colenso-Semple all about how the menstrual cycle and how it should affect your workout programming. Should you change your workouts around your menstrual cycle? Find out by listening! Check out her instagram Read her paper on exercise and menstrual cycles Read her paper on protein synthesis throughout the …
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Zepbound vs Wegovy trial and compounded GLP-1s
44:15
44:15
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44:15Drs. Karl and Spencer discuss the topline results from Surmount 5 which put Zepbound (tirzepatide) against Wegovy (semaglutide) for weight loss. They also discuss some news around compounded GLP-1s. Learn: Weight loss and glycemic differences between tirzepatide and semaglutide What the FDA is thinking for compounded GLP-1s If you're not on Dr. Spe…
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Drs. Karl and Spencer chat with Dr. Shivani Misra, a metabolic specialist physician researcher from the UK, all about the various forms of diabetes mellitus. Learn: The types of diabetes mellitus The monogenic forms (some what refer to as MODY) The differences within type 2 diabetes Whether CGMs (continuous glucose monitors) are useful If low carb …
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A new way of delivering healthcare - Direct Primary Care
1:08:59
1:08:59
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1:08:59Drs. Karl and Spencer chat with AtlasMD - Dr. Josh Umbehr all about making healthcare cheaper using direct primary care. Learn: How cheap labs and and meds should be How cutting out the middlemen can help healthcare and decrease costs Find AtlasMD hereBy Docs Who Lift
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1st longer term tirzepatide study (3 years)
44:41
44:41
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44:41Drs. Karl and Spencer discuss the brand new 3 year study of tirzepatide in those with prediabetes along with a discussion on semaglutide treating osteoarthritis. Learn: If people lose weight and keep it off with tirzepatide How many people regain weight after stopping the medicine Long-term side effects If semaglutide helps with osteoarthritis Clic…
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Making America Healthy Again - Joe Rogan Podcast Review
53:12
53:12
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53:12Drs. Karl and Spencer invite Dr. Andrea Love back to the podcast to discuss a recent Joe Rogan podcast with Calley and Casey Means along with the concept of Make America Healthy Again and RFK jr. Learn: What the docs agree with. What they don't agree with. Is raw milk okay? Are cancer rates rising? and more Follow Dr. Andrea here https://www.instag…
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Drs. Karl and Spencer discuss all things cortisol and poke fun at the influencers who try to fear monger exercise due to cortisol increases. Learn: What is cortisol and what does it do? Is cortisol bad? Should you worry about cortisol increases with exercise? Should you take supplements to lower cortisol? and more…
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Drs. Karl and Spencer discuss their ideal healthcare delivery system. Learn: Spencer's journey building and selling Sequence and what he wants to do next. How Dr. Karl believes healthcare should be and what he's doing next. Click here to get on Dr. Spencer's waitlistBy Docs Who Lift
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Obesity medicine updates and Kardashian supplements
40:13
40:13
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40:13Drs. Karl and Spencer discuss BS supplements claiming to be like Ozempic along with discuss some new obesity drugs coming down the pipeline that were announced in phase 1 and 2 trials. Are there any supplements that can mimic Ozempic? What is amylin and how does it help with weight and sugars? What is this new oral drug "amycretin" in phase 1 trial…
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Drs. Karl and Spencer chat with Dr. Jen Gunter all about menopause. Learn: How it's diagnosed. When and when not to treat. The various treatment. If it is indicated for cardiovascular disease prevention or body composition. Whether or not you should get labs. See more at Dr. Gunter's websiteBy Docs Who Lift
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Olympic controversies and GLP-1 for Alzheimer's and Heart Failure
27:26
27:26
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27:26Drs. Karl and Spencer talk about the top line results from study showing liraglutide may have some benefit in Alzheimer's along with top line results from the Summit trial showing heart failure benefits with tirzepatide. They also discuss the women's boxing controversy and BMI in athletes.By Docs Who Lift
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Drs. Karl and Spencer chat with return guest and bone expert endocrinologist Dr. Rachel Pessah-Pollack all about the new Vitamin D guidelines. Should healthy people even check a vitamin D level? Should they supplement with vitamin D? What people should check or supplement? Click here for the new guidelines…
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Does semaglutide cause blindness? What is NAION (nonarteritic anterio ischemic optic neuropathy)? What about worsening of diabetic retinopathy with semaglutide? What can you do to minimize the risk of NAION and retinopathy? Get the full study here Read Dr. Brugger's blogBy Docs Who Lift
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Tirzepatide may be a good option if you have obesity and obstructive sleep apnea. Click here to read the studyBy Docs Who Lift
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Click here to read about the gastric ablation and trial. Click here to see Dr. McGowan's clinicBy Docs Who Lift
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Drs. Karl and Spencer discuss the recent FLOW trial where semaglutide was found to be kidney protective. They also go off about the costs of these medicines and what to do (including compounding considerations). Click here to see the studyBy Docs Who Lift
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Drs. Karl and Spencer discuss the most recent South Park episode where GLP-1 medicines are discussed along with the dysfunctions of our healthcare system among other issues.By Docs Who Lift
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Drs. Karl and Spencer discuss the fallacies of functional medicine. You'll learn what functional medicine is and whether you should seek it out.By Docs Who Lift
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Another response to Jillian Michaels and Bill Maher
20:24
20:24
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20:24Drs. Karl and Spencer respond to Jillian Michaels on the Bill Maher showBy Docs Who Lift
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Bariatric surgery through the mouth? Endoscopy gastroplasty 101
38:36
38:36
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38:36Drs. Karl and Spencer discuss with gastroenterologist Dr. McGowan all about endoscopic gastroplasty. See recent study on cost effectiveness of endoscopic gastroplasty vs semaglutide Check out his programBy Docs Who Lift
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GLP-1 meds and Parkinson's and Heart Failure
24:11
24:11
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24:11Drs. Karl and Spencer discuss the new studies about GLP-1 medicines and Parkinson's and heart failure along with how these meds are not just weight loss drugs but health promoting medicines. Click here to see the Parkinson's study Click here to see the heart failure studyBy Docs Who Lift
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Drs. Karl and Spencer chat with Kasey Potts all about her journey with lipedema. Learn more about how this condition is diagnosed and treated. Check out her instagramBy Docs Who Lift
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Drs. Karl and Spencer chat with Dr. Amron all about lipedema. He is a specialized surgeon who treats lipedema daily. Learn about diagnosing and treating this condition that is commonly mistaken with obesity. Check his sites https://www.dramronconsultations.com/ https://www.advancedlipedematreatment.com/…
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GLP-1 Weight Loss Maintenance from Exercise
21:03
21:03
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21:03Drs. Karl and Spencer discuss a new study showcasing the importance of exercise during and after GLP-1 medicine use. Click here to see the original study Click here to see the extension studyBy Docs Who Lift
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Drs. Karl and Spencer discuss a recent Mark Hyman podcast where he perpetuated some myths about obesity and GLP-1 receptor agonist medicines.By Docs Who Lift
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