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Welcome to the MedEvidence! podcast, hosted by Dr. Michael Koren. MedEvidence, where we help you navigate the real truth behind medical research with both a clinical and research perspective. In this podcast, we will discuss with physicians with extensive experience in patient care and research. How do you know that something works? In medicine, we conduct clinical trials to see if things work! Now, let's get to the Truth Behind the Data. Contact us at www.MedEvidence.com
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If you have a goal of getting healthy and losing weight then this podcast is for you! Join Dr Steve as he helps you navigate your way to an optimized health journey. You will learn weight loss tips and strategies that are simple and sustainable. This podcast is for you if you are searching for answers to questions such as: How to lose weight and keep it off? Is the keto diet right for me? Should I use a low carb diet? What foods are best for weight loss? What are the best exercises for weigh ...
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“Got Knowledge Doc” Podkast with Dr. RR Baliga The "Got Knowledge Doc" Podkast, hosted by Dr. Ragavendra R. Baliga, is a knowledge-driven platform designed for physicians and healthcare providers seeking to stay at the forefront of medical science and innovation. With a distinguished career in cardiovascular medicine and academic leadership, Dr. Baliga engages with leading experts to explore cutting-edge research, emerging technologies, and transformative insights in medicine and beyond. Eac ...
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Experience these in-depth interviews with the fighters that BEAT their chronic health issues NATURALLY by following a 120 program designed by Dr. Reese. These interviews were the catalyst for Dr. Reese writing the popular book, THE PEOPLE VS CHRONIC ILLNESS: The Evidence, Knowledge and Solution to Becoming Pain & Drug-Free.
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The Jersey PodCats

Danielle Woolley & Elizabeth Gearhart

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If you love talking about cats, but your friends and family are kind of over it, this is the podcast for you! Join your hosts, Danielle Woolley and Elizabeth Gearhart, on The Jersey PodCats for entertaining conversations with everyday cat lovers talking about life, cats and everything in between! Follow us on Facebook, Instagram, Youtube and everywhere you listen to podcasts.
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Dr Maulfair's 40+ years of clinical experience offering treatment protocols designed to avoid prescription drugs has resulted in thousands of patients regaining health and many more avoiding health problems in the first place. Aging gracefully without complications from chronic, degenerative diseases and health problems IS within your reach and very possible with his medical care. Get Answers Instead of Prescriptions with this weekly podcast.
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Dr Alok Purohit is a practicing life & Health coach, Ex Corporate CEO, Certified by ICF, he specializes in executive/entrepreneur coaching and family business coaching. Certified by EACCME, He coaches individuals on diabetes and other metabolic/ Lifestyle diseases, mostly helps them to manage/reverse their condition through education, empowerment and holistic lifestyle modification. You may find empowering podcasts relating to life coaching, health and nutrition and specifically on diabetes ...
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🚨 New NEJM Study on Olezarsen 🚨 In patients with moderate hypertriglyceridemia and elevated cardiovascular risk, monthly subcutaneous olezarsen reduced triglycerides by over 60% at 6 months! 📉💥 ✅ Significant drops in APOC3, VLDL, remnant & non-HDL cholesterol ✅ No rise in LDL-C ✅ Well-tolerated with mild injection-site reactions 🔬 APOC3 inhibition …
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Send us a text Join Cardiologist Dr. Michael Koren as he speaks in front of a live audience to break down the truth about triglycerides. Triglycerides are a type of fat in our blood that acts as an energy source for the body, but high levels can have serious impacts on your heart and health. Dr. Koren explains what triglycerides are, what they do i…
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In this episode, Dr. Steve breaks down the process of triglyceride production and how you can naturally lower your triglycerides by making healthier food choices. He explains how glucose and insulin play a major role in fat storage, the importance of maintaining low insulin levels, and how choosing the right foods can help reverse health conditions…
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☀️ Walking on Sunshine? Rethinking Our Relationship with the Sun! 🧴🧬 New research—spotlighted in The Economist (Sep 20, 2025)—challenges old assumptions: Could moderate sun exposure reduce cardiovascular mortality? ❤️📉 From nitric oxide to vitamin D, this FAQ explores the science, nuance, and shifting global guidelines. Let’s talk melanin, mortalit…
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Picture an atherosclerotic artery as a crime scene. Cholesterol piles up on the walls — thick deposits blocking what should be a free-flowing highway of blood. For decades, cholesterol was blamed as the culprit. But here’s the twist: cholesterol is just the passenger. The real suspects are the lipoproteins — the vehicles smuggling cholesterol into …
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🚨 Cardiogenic Shock—A Decade Later The DanGer Shock Trial shows that patients with STEMI and shock treated with the Impella CP microaxial flow pump lived 600 more days over 10 years vs standard care alone. 📉 Mortality: 52.5% vs 68.8% (HR 0.70) 🛠️ Despite higher adverse events, the survival benefit endured a full decade. 📊 This changes how we think …
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🧠 Hypertrophic Cardiomyopathy — A Masterclass from Eugene Braunwald 🧬 📌 Just published in NEJM (Aug 2025): a sweeping, state-of-the-art review on HCM — from Teare’s first autopsy to myosin inhibitors, AI diagnostics, and gene therapy. 💥 Clinical insights, historical depth, trial data (EXPLORER-HCM, SEQUOIA-HCM, VALOR-HCM), and future-facing advance…
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Send us a text Dr. Michael Myers joins Dr. Michael Koren for an interview about his physician journey from medical school to private practice, healthcare administration, health consulting, teaching, and writing. Dr. Myers talks about his serendipitous journey through many parts of the healthcare system and how this shaped his unique career path thr…
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Blair LaCorte is the Vice Chair of the Board of Directors at the Buck Institute for Research on Aging—the world’s first biomedical research institution dedicated solely to understanding aging and age-related diseases, and the largest independent scientific institute in the Bay Area. A seasoned leader and strategist, Blair has a track record of tran…
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🌸 Dōgen Zenji (1200–1253), founder of the Sōtō Zen school in Japan, taught that true practice lies in zazen—“just sitting” 🧘‍♂️—where enlightenment and practice are inseparable. His Shōbōgenzō continues to inspire mindfulness & presence today. ⏳✨ #Zen #MindfulnessBy MasterMedFacts LLC
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Send us a text Dr. Michael Koren joins Kevin Geddings to share insights from his recent meeting with Alzheimer's expert Dr. Reza Bolouri. The doctor highlights advances in understanding the disease's progression, mechanisms, and treatment options. This progress offers new hope for patients through early screening, diagnosis, and medications that ha…
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In this episode, Dr. Steve and his wife, Theresa, chat with Victor Prince of Southern Keto about his wake-up call in the corporate grind and how he rebuilt his health with real food. They break down Victor’s “3 main food groups,” simple swaps for Southern classics, which fats to actually cook with, why homemade probiotic yogurt matters, how to spot…
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Aaron Straker is a N.A.S.N. Licensed Primary Sports Nutritionist. He prefers a pragmatic approach to nutrition that focuses on simple food selection, the importance of nutrient density, and the importance of objectivity in dieting and reporting. Today on Barbell Shrugged we dive into Straker’s path to becoming and IFBB Pro. From injury, setbacks, d…
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Send us a text Dr. Michael Koren joins Kevin Geddings to discuss the importance of taking reasonable precautions for health and safety. He recounts his experience at a recent Jacksonville Jaguars football game, which was delayed out of an abundance of caution due to a lightning storm. Dr. Koren explains that although the delay was annoying and disr…
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In this episode, Dr. Steve breaks down the essential nutrients our bodies need and how to fuel ourselves the right way. He talks about the importance of amino acids, fatty acids, vitamins, minerals, and glucose, and why some food groups are crucial while others can actually do more harm than good. Tune in to learn about the true building blocks of …
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🚨 New Evidence in NSTEMI Care! 🫀 The SLIM Trial shows that FFR-guided complete revascularization during the index procedure in patients with NSTEMI and multivessel disease significantly reduces death, MI, stroke, and repeat PCI compared to culprit-only PCI. 🎯 Key win? Fewer revascularizations, better outcomes — physiology beats anatomy again. 📚 Pub…
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Cholesterol is one of the most talked-about molecules in medicine — and one of the most misunderstood. It’s essential for life, but when carried in the wrong lipoproteins, it becomes the driving force behind atherosclerosis. In this episode of LipidCurious, we step away from the headlines and hype to explore what cholesterol really means for clinic…
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💥 Practice-Changing Evidence in HFpEF! 💥 In a real-world cohort of 97,000+ patients with obesity & type 2 diabetes, semaglutide and tirzepatide reduced risk of heart failure hospitalization or death by over 40% 📉 ⚖️ No meaningful difference between the two agents. 🧠 Findings reinforce STEP-HFpEF & SUMMIT trials and highlight GLP-1 therapies’ expand…
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In today’s episode of Barbell Shrugged, we'll be discussing the various factors that impact brain health and exploring strategies for optimizing brain function. First, we'll be discussing the impact of exercise on brain health. Research has shown that regular exercise can help to improve brain function, enhance cognitive performance, and even reduc…
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📢 Just read the #AMALFI trial in JAMA 📰 — a landmark remote RCT of AF screening using 14-day ECG patches mailed to older adults at stroke risk 📦🫀. At 2.5 years, the patch group had a modestly higher AF detection rate (6.8% vs 5.4%, p=0.03) and increased anticoagulation use 💊🧠. Stroke rates were similar ⚖️. 🎯 Key takeaway: Remote, mail-based AF scre…
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🚨 New Trial Alert 🚨 Can we safely stop anticoagulation after AF ablation? The ALONE-AF Trial 🫀 suggests yes—in selected patients with no AF recurrence, stopping DOACs reduced major bleeding 🌟 without increasing stroke risk 🧠. 📉 0.3% vs 2.2% for the composite outcome (P = .02) 📍 Carefully monitored, low-risk patients may benefit most. 📝 Editorial: R…
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🚨 New Findings from the HELP-MI Trial! 🇸🇪🧪 Can routine Helicobacter pylori screening during acute myocardial infarction (MI) hospitalization prevent upper gastrointestinal bleeding (UGIB)? 💉 Over 18,000 patients across 35 Swedish hospitals 📉 Result: No significant reduction in UGIB overall (RR 0.90; P=0.18) 🔍 BUT: Clear benefit in patients with ane…
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Melissa is a performance physical therapist and is heavily involved in the CrossFit space as a healthcare provider, as well as an athlete. Melissa grew up in the Metropolitan New York area, but now resides in the Tampa Bay area. Upon graduating from PT school, Melissa started working in an outpatient orthopedic physical therapy practice, but was un…
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Send us a text The conversation between Dr. Michael Koren and Dr. Zeke Emanuel continues in part 2. Bioethicist Zeke Emanuel dives into the unethical Tuskeegee study and landmark Belmont Report in 1979 and how many safeguards to clinical research are currently in effect. They doctoral duo also talk about how in spite of the potentially off-putting …
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Send us a text Dr. Michael Koren joins Kevin Geddings to report live from Madrid on new developments being presented at the European Society of Cardiology meeting. This medical gathering, now the world's largest, is a showcase of developments in heart health and medicine. Dr. Koren notes excitement about progress in treating a genetic condition, li…
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🩺 New Insights on Apixaban for VTE! 📢 The HI-PRO trial challenges the old 3-month rule for provoked VTE. 📉 Extended low-dose apixaban (2.5 mg BID) reduced recurrent VTE from 10.0% ➡️ 1.3% with minimal major bleeding. 🎯 Editorial in NEJM urges a shift from binary labels (“provoked vs unprovoked”) to a patient-centered, risk-adapted approach. 🧠 Art m…
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🌏 Zhu Xi (1130–1200), a master of Neo-Confucianism, reshaped Chinese philosophy with his focus on rationality, self-cultivation & education. His commentaries on the Four Books guided civil service exams for centuries across East Asia. 📚✨ #Leadership #Philosophy #History #ConfucianismBy MasterMedFacts LLC
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Just read the latest from NEJM? The PIpELINe Trial 🇮🇹 changes how we approach cardiac rehab in older adults post-MI! 🧓❤️ 🎯 A 12-month, multidomain intervention — risk factor control, nutrition 🥗, and Otago-based exercise 👟 — cut CV death/hospitalization from 20.6% → 12.6% (P=0.01)! 📉 Hospitalizations for heart failure dropped 7.1% → 1.5%. No seriou…
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🚨 New Meta-Analysis Alert! 💊🫀 Can β-blockers benefit patients post-MI with mildly reduced ejection fraction (LVEF 40–49%)? 📊 An individual patient data meta-analysis (REBOOT, BETAMI, DANBLOCK, CAPITAL-RCT) shows a 25% reduction in the composite outcome of death, MI, or HF with β-blockers vs. control (HR 0.75; p=0.031) — even in the absence of clini…
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🚫💊 Should We Rethink Beta-Blockers Post-MI? In the landmark REBOOT trial (NEJM, 2025), beta-blockers failed to reduce mortality, reinfarction, or heart failure hospitalizations in post-MI patients with preserved ejection fraction (>40%). 💡 A modern, pragmatic trial across 109 centers (Spain + Italy 🇪🇸🇮🇹) with 8438 patients — shaking the foundation …
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🚨 New NEJM Study Alert! 🩺💔 Do beta-blockers still help after a heart attack if there’s no heart failure? 🤔 In the BETAMI–DANBLOCK trial (🇩🇰+🇳🇴, n=5574), beta-blocker therapy in post-MI patients with preserved or mildly reduced LVEF (≥40%) modestly reduced the composite outcome of death or major cardiovascular events 🧠📉 📌 Primary endpoint: 14.2% (BB…
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💥 New NEJM Trial Alert! A modest 0.3 mmol/L rise in potassium (via MRA, KCl, or diet) significantly reduced arrhythmias, ICD shocks, and hospitalizations in high-risk ICD patients ⚡🫀 📉 HR 0.76 for the composite endpoint 🔢 NNT = 12.3 over 3.3 years 🍌 Safe, scalable, and globally relevant 👉 Time to rethink “normal” K⁺ levels in cardiology! #Cardiolog…
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🚨 New RCT Alert from the NEJM! Can an old 💊 make a comeback in modern 💓 failure care? 📌 The DIGIT-HF trial showed that digitoxin, a cardiac glycoside with hepatic clearance, reduced the combined endpoint of all-cause death or HF hospitalization in HFrEF patients on contemporary guideline-directed therapy — including ARNI, beta-blockers, MRAs & SGLT…
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🚨 Calcific Aortic Valve Stenosis (CAVS): Beyond Wear and Tear 🫀🪨 Once thought to be “degenerative,” CAVS is now recognized as an active disease driven by oxidative stress ⚡, inflammation 🔥, and lipoprotein(a) 🧬. Despite its growing global burden, no drug therapy slows its progression. 🩺 Current management: Surgical (SAVR) or Transcatheter (TAVR) va…
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🚨 New in The Lancet (2025) 🚨 A mega meta-analysis of 484 RCTs (104K+ participants) offers a game-changing approach to hypertension management! 💊📉 Instead of guessing how much BP will drop, now you can predict it—by drug, dose, and combo! 🎯 Like statins for LDL, this study introduces low-, moderate-, and high-intensity BP regimens based on expected …
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In today’s episode of Barbell Shrugged Dan Garner dives into how you can start to analyze your yearly bloodwork for performance. Standard blood tests can be ordered around the globe, in every country, and are the gold standard for understanding basic health. The normal reference ranges, however, are not giving you the answers you are looking for wh…
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Send us a text Proteus was a Greek sea god who could change his form, much like obesity is able to in the body. Doctors Michael Koren, Victoria Helow, and Michael Bernhardt come together in front of a live audience for a discussion on the myriad effects obesity has in and on the body. The doctors move through how excess weight affects the heart, sk…
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🧒❤️ Partial Heart Transplant: A Growing Solution for Growing Hearts! 🌱🔬 🚨 Pediatric patients with congenital heart valve disease often face multiple surgeries due to non-living valve grafts that don’t grow. This landmark study from @DukeHealth shows how living valves via partial heart transplant can change the game. 📊 In 19 patients (median age: 97…
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🐖🫁 World First: Pig Lung Transplanted into Human 🧬🌍 In a groundbreaking step for xenotransplantation, a team in China successfully transplanted a genetically modified pig lung into a brain-dead human recipient. The lung functioned for 216 hours without hyperacute rejection, offering hope to thousands on organ waitlists. 🔬 Key breakthroughs: • 6-gen…
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🧬 Pre-Heart Failure? Let Age Speak! 👵👴 New study in JACC compares fixed vs age-adjusted NT-proBNP cutoffs for defining pre–heart failure (Pre-HF) in over 22,000 adults across ARIC, MESA, and CHS cohorts. 📉 Key Insight: Age-adjusted cutoffs reduce overdiagnosis in older adults 🧓 and improve risk prediction for heart failure hospitalization 🏥. 📊 With…
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Send us a text Dr. Michael Koren is joined by Dr. Ezekiel "Zeke" Emanuel, an oncologist, bioethicist, and former White House advisor. Dr. Emanuel talks about his enduring interest in bioethics and the importance of ethics in areas like clinical research. The two doctors also talk about shared experiences at Harvard Medical School and Dr. Emanuel's …
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🚨 Game-Changer in Lung Cancer! 🫁💉 The 5-year results from CheckMate 816 are in! Neoadjuvant nivolumab + chemotherapy significantly improved survival in resectable NSCLC 🎯 ✅ 65.4% 5-year OS vs. 55.0% with chemo alone 🧬 pCR = 95.3% survival 📉 ctDNA clearance = better outcomes ⚖️ Time to rethink neoadjuvant strategies 📚 Read in NEJM: A landmark in tho…
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Bryan Boorstein has 24 years of training and over 13 years of coaching experience. A 3-time CrossFit Regional athlete and CrossFit Games coach, Bryan holds a Bachelor of Science from JMU (2006) and certifications in CrossFit L-2 and Mobility. As the owner and founder of Evolved Training Systems and Paragon Training Methods, he’s a trusted name in f…
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🚨 New insights from EHJ 2025! 🚨 In statin-treated patients undergoing PCI, inflammation (hsCRP ≥2 mg/L)—not elevated LDL-C—was the strongest predictor of MACE at 1 year 🔥🧪 📊 Bay et al. show that residual inflammatory risk carries a 1.8x higher hazard for adverse events, while LDL-C alone showed no independent risk 💥 🧠 Time to shift focus beyond lip…
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🔎 Averroes (Ibn Rushd, 1126–1198), the “Father of Rationalism,” bridged Islam & the West through philosophy, medicine & law. 🌍 His commentaries on Aristotle, theory of the intellect, and medical insights (stroke, Parkinson’s, retina) shaped centuries of thought. 📚 His legacy reminds us that reason, faith & science can coexist in pursuit of truth. 💡…
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Send us a text Dr. Michael Koren joins Kevin Geddings to wax nostalgic about the past generation and what has changed for the better and for the worse. They note that there have been improvements in areas like food, but that air travel and the healthcare experience have deteriorated precipitously. They then contrast this with the massive improvemen…
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🚨 New Study Alert 🧬🫀 Think a CAC score of zero means you’re in the clear? Think again. A massive cohort from the Western Denmark Heart Registry (n = 23,777) shows that elevated LDL-C is strongly associated with non-calcified plaque 🧱 and future coronary events 💥—even in those with CAC = 0. 📈 Each 1 mmol/L (~39 mg/dL) rise in LDL-C increases the odd…
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🚨 New in NEJM 🫁: The IMPALA-2 trial shows that inhaled molgramostim significantly improves gas exchange, quality of life, and exercise capacity in patients with autoimmune pulmonary alveolar proteinosis (aPAP)—a rare disease driven by GM-CSF autoantibodies. 💨 Say goodbye to whole-lung lavage—this is a bench-to-bedside success story 30 years in the …
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In this episode, Dr. Steve talks with Dr. Rachel Schuck, an expert in integrative healthcare and clinical nutrition, about the invisible force shaping your health: your gut. Dr. Schuck explains the vital role gut health plays in everything from metabolism to mood and offers insights into how food, lifestyle, and holistic approaches can heal and bal…
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🚨 New Stroke Trial Alert! 🧠💉 Can IV alteplase help beyond the 4.5-hour mark? The HOPE trial (JAMA 2025) says YES—if perfusion imaging shows salvageable brain tissue 🧬🕑. 📊 Functional independence at 90 days improved from 26% ➡️ 40%, despite a small uptick in symptomatic ICH (3.8%). 🌍 Game-changer for patients in low-resource settings where thrombect…
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