Best Protein Engineering Podcasts (2025)

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Introducing Profluent’s E1: Retrieval-augmentation for protein engineering 6:38

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10h ago6:38

6:38

Understanding how protein sequence encodes structure and function remains one of the central challenges in the life sciences. Yet most protein language models still treat each sequence as an isolated datapoint. This forces the entire burden of evolutionary context into model parameters, which leads to blind spots in underrepresented families and am…

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Episode: 79 - Conversation with Bahija Jallal on the Biggest Anticipated Transformations and Breakthroughs 42:46

1h ago42:46

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November 11, 2025 | What is the next modality to focus on in the next 10 years? For Bahija Jallal, CEO of Immunocore, it would be T-cell engagers. In this episode of The Chain, host Rakesh Dixit speaks with Jallal on the potential advantages of bispecific T-cell engager therapy versus T-cell receptor therapy, biggest anticipated changes in drug dis…

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The Art of Protein Engineering 20:35

9d ago20:35

20:35

Carter Mitchell, Chief Scientific Officer at Kemp Proteins, brings scientific rigor and an artist’s imagination to the world of protein design and production. In this episode, recorded at the Advanced Lateral Flow Conference, we explore how his company is pushing the boundaries of protein expression, quality, and analysis using tools that merge mac…

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A headless mystery, and a deep dive on dog research 32:35

4m ago32:35

32:35

First up on the podcast: the mysterious fate of Europe’s Neolithic farmers. They arrived from Anatolia around 5500 B.C.E. and began farming fertile land across Europe. Five hundred years later, their buildings, cemeteries, and pottery stopped showing up in the archaeological record, and mass graves with headless bodies started to appear across the …

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Profluent raises $106M from Jeff Bezos 4:48

9h ago4:48

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Profluent builds frontier AI systems to unlock programmable biology. Now, Profluent has raised $106M led by Bezos Expeditions and Altimeter, with continued support from Spark, Insight, and Air Street. The company is now the largest position in Air Street’s second fund. This new capital accelerates the company’s path toward scaling frontier protein …

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20VC: Cursor Raises $2.3BN: Who Wins the Coding War | Peter Thiel and Softbank Sell NVIDIA: Analysed | Why Venture Capital Will Hit $1TRN and the Opening of Retail | Why Stripe and the Best Companies Will ... 1:22:38

5h ago1:22:38

1:22:38

AGENDA: 04:47 Cursor Raises $2.3BN at $29BN Valuation 11:36 What Gemini 3 Means for Lovable, Cursor and Replit 30:54 Peter Thiel and Softbank Sell NVIDIA: The Bubble Bursting? 48:54 Oracle Credit Default Swaps: The Risk is Increasing 01:07:22 Stripe Does Tender at All-Time High: Why the Best Companies Will Never IPO 01:19:18 Why Retail WIll Cause a…

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ALFC Double Feature - Making Lateral Flow Accessible Everywhere 29:06

2h ago29:06

29:06

This episode is a double from my visit to the Advanced Lateral Flow Conference. Usability is Innovation: Atomo Diagnostics Atomo Diagnostics set out more than a decade ago to solve a surprisingly human problem in diagnostics: complexity. Founder John Kelly describes how even the best rapid tests—validated in pristine lab environments—often fail whe…

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Precision Muscle Analysis with Matt Brown of Springbok Analytics #824 55:13

24m ago55:13

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In this episode, Anders Varner, Doug Larson, and Travis Mash sit down with Matt Brown, Director of Business Development at Springbok Analytics, to explore the cutting edge world of MRI based muscle analysis. Matt breaks down the origins of Springbok, how the company grew from a university research lab solving cerebral palsy surgical problems into o…

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David Gutmann – Cancer Neuroscience and the Sociobiology of Brain Tumors 59:27

24m ago59:27

59:27

Brain tumor cells interact with neurons, glial cells, and immune cells in complex ways that often benefit the cancer cells while compromising the function of normal neural cells. In this episode I talk with Washington University Neurology Professor David Gutmann about brain cancer cells and their communication with surrounding normal cells. A major…

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A climate COP out? 31:43

13h ago31:43

31:43

Today, we're analysing the COP30 conference in Brazil, asking whether the will to tackle climate change is drying up. Like this podcast? Please help us by supporting the Naked ScientistsBy The Naked Scientists

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Poolside acquires Fern Labs 7:37

2d ago7:37

7:37

Poolside is building one of the strongest full-stack AI companies in the world: energy, compute, models, and the infrastructure needed to run multi-agent systems for complex enterprise workflows. The Fern team brings a deeply opinionated agentic core - built from first principles and stress-tested on real workloads - into a company with scale, dist…

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Tackling TriDot Workouts: Race Rehearsals 58:04

1h ago58:04

58:04

As you near the end of your triathlon stamina build and approach race day, it’s time for one of the most important parts of your training: the race rehearsal. This workout isn’t just a test of your fitness, it’s a full practice run for race day, from your gear and nutrition to your pacing and mindset. In this episode, Coach Elizabeth James joins ho…

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20VC: Andrew NG on The Biggest Bottlenecks in AI | How LLMs Can Be Used as a Geopolitical Weapon | Do Margins Matter in a World of AI? | Is Defensibility Dead in a World of AI? | Will AI Deliver Masa Son ... 1:02:53

2d ago1:02:53

1:02:53

Dr. Andrew Ng is a globally recognized leader in AI. He is Founder of DeepLearning.AI, Executive Chairman of LandingAI, General Partner at AI Fund, Chairman and Co-Founder of Coursera. As a pioneer in machine learning Andrew has authored or co-authored over 200 research papers in machine learning, robotics and related fields. In 2023, he was named …

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20Product: How AI Changes Product Design | Does the Design Phase Become Irrelevant in a World of Vibe Coding | The Five Pillars of Truly Great Product Design with Carl Rivera, Chief Design Officer at Shopify ... 1:11:23

6d ago1:11:23

1:11:23

Carl Rivera is the Chief Design Officer at Shopify, where he previously led both Merchant Services and the Shop App as VP of Product. Before joining Shopify through its acquisition of Tictail, Carl was the co-founder and CEO of Tictail, the "Tumblr for e-commerce," where he built one of the most beloved design-forward commerce platforms of its era.…

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Flu season starts early, and staving off hungry seagulls 28:06

13h ago28:06

28:06

In the news show, flu season starts early in the Northern hemisphere due to pesky new strains, so will vaccines be effective? Also, the baby 'swim cap' which promises less invasive brain monitoring, and the European Space Agency's GPS powered satellites which are surveying the water cycle. Then, we find out the best way to shout at seagulls to stop…

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Solving the ‘golfer’s curse’ and using space as a heat sink 28:13

5d ago28:13

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First up on the podcast, Online News Editor David Grimm joins host Sarah Crespi for a rundown of online news stories. They talk about lichen that dine on dino bones, the physics of the lip-out problem in golf, and a brain-computer interface that can decode a tonal language (Chinese) from brain waves. Next on the show, Jeremy Munday, a professor of …

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20VC: Sequoia's Leadership Transition | Michael Burry Shorts NVIDIA and Palantir | Gamma Raises $100M at $2BN | Has Defensibility Died in a World of AI | Datadog Surges as Duolingo Plummets: What is Happening ... 1:15:50

7d ago1:15:50

1:15:50

AGENDA: 04:22 Sequoia's Leadership Transition 09:46 Michael Burry's Big Short on Nvidia and Palantir 17:41 Gamma Raises $100M at a $2BN Valuation 32:34 Does Defensibility Exist Today When Copying is Easy 40:31 Should All Funds Be Way More Diversified 47:12 How to Run a Fundraising Process & What Not To Do 57:57 Datadog Surges 20% and Duolingo Crash…

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Ray Dorsey: Environmental Toxins and Parkinson's Disease – Evidence and What to Avoid 57:26

9h ago57:26

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There is considerable evidence that exposure to certain chemicals in the environment cause Parkinson's disease in many people. In this episode neurologist Ray Dorsey talks about some of the chemicals that may cause Parkinson's disease including the pesticides paraquat and rotenone, and trichloroethylene and perchloroethylene which are chemicals use…

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Measuring Muscle Mass Percentage with Dr. Chris Perry, Anders Varner, Travis Mash and Doug Larson #823 45:41

6d ago45:41

45:41

In this week's episode of Barbell Shrugged, Anders Varner, Doug Larson, Coach Travis Mash, and Dr. Chris Perry dive deep into the real science of muscle mass, why it's the single most important tissue in the human body and what happens when you don't have enough of it. They cover everything from how muscle mass impacts disease risk, hormone balance…

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80 years of nuclear weapons 31:34

7d ago31:34

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In this edition of The Naked Scientists, we go nuclear, and explore the science and politics of weapons of mass destruction... Like this podcast? Please help us by supporting the Naked ScientistsBy The Naked Scientists

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Battling Burnout: 7 Ways to Reignite Your Triathlon Passion 1:01:48

36m ago1:01:48

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The ebbs and flows of triathlon motivation are real, and many athletes can face burnout at some point in their sporting journey. It’s a normal part of the athlete journey, but it doesn’t have to derail your love for the sport. This week, Coaches Stephen Horan and Matt Davies join Andrew to share seven practical tips for preventing and overcoming bu…

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20VC: Benchmark's Newest General Partner Ev Randle on Why Margins Matter Less in AI | Why Mega Funds Will Not Produce Good Returns | OpenAI vs Anthropic: What Happens and Who Wins Coding | Investing Lessons ... 1:25:43

11d ago1:25:43

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Ev Randle is a General Partner @ Benchmark, one of the best funds in venture capital. In their latest fund, they have Mercor ($10BN valuation), Sierra ($10BN valuation), Firework ($4BN valuation), Legora ($2Bn valuation) and Langchain ($1.4Bn valuation). To put this in multiples on invested capital, that is a 60x, two 30x and two 20x. Before Benchm…

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State of AI: November 2025 newsletter 33:32

6h ago33:32

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Welcome to the latest issue of the State of AI, an editorialized newsletter formerly known as Guide to AI that covers the key developments in AI policy, research, industry, and start-ups over the last month. First up, a few reminders: Read more on press.airstreet.com

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20Sales: Why You Need a CRO Pre-Product | Why Remote Sales Teams Do Not Work | How Snowflake Built a Sales Machine with Chad Peets 1:09:13

13d ago1:09:13

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Chad Peets is one of the greatest sales leaders and recruiters of the last 25 years. From 2018 to 2023, Chad was a Managing Director at Sutter Hill Ventures. Chad has worked with the world's best CEOs and CROs to build world-class go-to-market organizations. Chad is currently a member of the Board of Directors for Lacework and Luminary Cloud and on…

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Vaping rates surge, and space race to deliver economic boon 29:36

12d ago29:36

29:36

In this edition of The Naked Scientists: Among British people vapers now outnumber smokers for the first time. From Big Bang to Big Crunch - the new theory showing the expansion of the Universe might be slowing down. And, evidence that our early ancestors, three million years ago, may have excelled at DIY!Linda - So these are the annual population …

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Understanding early Amazon communities and saving the endangered pocket mouse 35:03

9d ago35:03

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First up on the podcast, Contributing Correspondent Sofia Moutinho visited the Xingu Indigenous territory in Brazil to learn about a long-standing collaboration between scientists and the Kuikuro to better understand early Amazon communities. Next on the show, we visit the Pacific pocket mouse recovery program at the San Diego Zoo Wildlife Alliance…

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20VC: Navan IPO: Winners, Losers and is a $4.5BN Exit Enough in VC Today | Harvey Raises $150M at $8BN Price | Why Google is a Buy and Amazon is a Sell | Meta Down 10%, Is Zuck Struggling? 1:16:23

14d ago1:16:23

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AGENDA: 04:27 Navan's IPO: Winners, Losers and 20% Crater 12:55 Harvey Raises $150M at an $8BN Valuation 35:36 Was Sam Altman Wrong to Snap at Brad Gerstner 41:25 Why GOOG is a Buy and Amazon is a Short 47:43 Meta Down 10%, Buy or Sell? 51:12 If You Have Not Accelerated with AI, You Are Dead 01:05:20 Why Now is the Best Time for Series A and Worst …

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Cardio Isn’t The Hero, Protein Is 19:09

8d ago19:09

19:09

We unpack why progress can stall for women over 35 even with consistent training, and how smart metrics reveal what the mirror misses. We share the five biggest mistakes, real numbers from our own scans, and the exact fixes that restore muscle, reduce fat, and calm stress. • who this is for and why the scale misleads • lessons from competing and un…

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Rebuilding Strength and Purpose, Travis Mash's Path Back to the Platform w/ Anders Varner, Travis Mash and Doug Larson #822 41:47

6d ago41:47

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In this episode, Anders Varner, Doug Larson, and Travis Mash sit down for a story that is equal parts comeback and evolution. After a hip replacement and years away from competition, Mash, now over 50 years old, stepped back onto the powerlifting platform to go nine for nine and set new age group world records. He breaks down how he rebuilt his bod…

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Episode 188: Marina Walther-Antonio discusses the microbiome’s role in women’s health and cancer 1:19:16

2d ago1:19:16

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Today we have Dr. Marina Walther-Antonio, a Mayo Clinic researcher who investigates the role of the microbiome in cancer and reproductive health, particularly endometrial and ovarian cancers. According to the World Cancer Research Fund International, endometrial and ovarian cancers are among the top 10 most prevalent cancers in women worldwide, and…

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PARIMA’s first regulatory approval and another wake-up call for Europe 2:38

8d ago2:38

2:38

PARIMA, a global leader in cultivated proteins, has become the first European company to secure regulatory approval for cultivated meat, with the Singapore Food Agency granting clearance for its cultivated chicken. It’s a historic moment for Europe’s food-tech sector, but one that’s unfolding thousands of miles away from home.…

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The National Physical Laboratory at 125 32:48

12d ago32:48

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In this edition of The Naked Scientists, we go behind the scenes at the National Physical Laboratory as it celebrates 125 years at the forefront of science... Like this podcast? Please help us by supporting the Naked ScientistsBy The Naked Scientists

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A Triathlete's Guide to Protein 58:58

3d ago58:58

58:58

This week, we’re diving deep into protein intake! Discussing how much you really need, which sources are best, and how to get it right for your training goals. Andrew is joined by Advanced Sports Dietitian Taryn Richardson to unpack the science behind protein and its crucial role in athletic performance. Together, they explore how to adjust protein…

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20VC: Cohere's Chief AI Officer on Why Scaling Laws Will Continue | Whether You Can Buy Success in AI with Talent Acquisitions | The Future of Synthetic Data & What It Means for Models | Why AI Coding ... 57:34

18d ago57:34

57:34

Joelle Pineau is the Chief AI Officer at Cohere, where she leads research on advancing large language models and practical AI systems. Before joining Cohere, she was VP of AI Research at Meta, where she founded and led Meta AI's Montreal lab. A professor at McGill University, Joelle is renowned for her pioneering work in reinforcement learning, rob…

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20VC: Tim Ferriss: Why I Walked Away From Angel Investing After Uber | How I Accidentally Lost $150 Million | Money Fixed My Problems—Then Made Me Miserable 1:31:49

21d ago1:31:49

1:31:49

🎧 20VC x Tim Ferriss — Full Episode Timeline 00:00 – "How Do You Stay True to Yourself When You Have to Perform for the World?" 06:00 – "Why Tim Ferriss Refused to Go All-In on YouTube" 09:00 – "You Don't Need 10 Million Fans—You Need 1,000 True Believers." 12:00 – "The Internet Is Not a Relevance Machine—It's a Sensationalism Machine." 15:00 – "Mo…

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Hurricane Melissa's wake, and alcohol-free beer with a buzz 35:47

12d ago35:47

35:47

In this edition of The Naked Scientists: How the latest science helped the Caribbean prepare for Hurricane Melissa. Also ahead, the alcohol-free beers providing a 'buzz' without the hangover. And, why a German warehouse is simulating a European Moon landing... Like this podcast? Please help us by supporting the Naked Scientists…

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Detecting the acidity of the ocean with sound, the role of lead in human evolution, and how the universe ends 45:27

7d ago45:27

45:27

First up on the podcast, increased carbon dioxide emissions sink more acidity into the ocean, but checking pH all over the world, up and down the water column, is incredibly challenging. Staff Writer Paul Voosen joins host Sarah Crespi to discuss a technique that takes advantage of how sound moves through the water to detect ocean acidification. Ne…

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20VC: a16z Raises $10BN in New Funds | Mercor Raises $350M at a $10BN Valuation | OpenAI Restructuring: Who Wins and Who Loses | Why IRR is a BS Metric and Three Ways to Win in VC Today 1:24:09

22d ago1:24:09

1:24:09

AGENDA: 05:17 OpenAI's Restructuring: Winners and Losers 17:17 Andreessen Horowitz's Raise $10BN in New Funds 26:38 Mercor Raises $350M at a $10BN Valuation 43:08 Spray and Pray: Does it Work: Data Breakdown 47:04 The Role of Option Checks Venture Capital 48:36 The Three Ways to Win in VC Today 54:26 Why IRR is a BS Metric and What Matters More 01:…

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Ai Yamamoto: "ALFY" Cleanses Neurons of Pathological Proteins to Counteract Degenerative Diseases 1:12:11

20d ago1:12:11

1:12:11

A shared feature of neurodegenerative disorders is accumulation of aggregated proteins within neurons: Tau in Alzheimer's disease; alpha-synuclein in Parkinson's disease; huntingtin in Huntington's disease; and TDP43 in amyotrophic lateral sclerosis. In this episode Ai Yamamoto – an Associate Professor Neurology at Columbia University – talks about…

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Gourmey acquires Vital Meat and forms PARIMA to industrialize of cultivated food 3:31

8d ago3:31

3:31

Building a next-generation food company.

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Escaping the Transactional Trap to Build Impact-Driven Success with Master Coach Angie Wisdom 33:35

8d ago33:35

33:35

Feeling accomplished but oddly empty? We sat down with master certified coach, author, and Fortune 500 speaker Angie Wisdom to unpack why high achievers slip into a transactional loop—and how to rebuild success around alignment, self-trust, and impact. Angie shares how her pivot from finance to coaching revealed a simple truth: when values vanish f…

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The Science of Sleep and Recovery w/ Dr. Allison Brager, Anders Varner, Travis Mash and Doug Larson #821 49:44

8d ago49:44

49:44

In this episode, neuroscientist and U.S. Army sleep expert Dr. Allison Brager joins Anders Varner, Doug Larson, and Travis Mash to explore the real science behind sleep, recovery, and wearable technology. They discuss which devices actually deliver useful data, such as the Oura Ring for sleep tracking and Garmin for cardiovascular measurements, and…

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Proteomics promises a revolution in preventative medicine 29:27

23d ago29:27

29:27

Today, in association with Proteomics International, we're hearing about a new era in medicine where we can tell people not what diseases they've got, but what ones they will have in ten years' time, giving them a chance to turn things around... Like this podcast? Please help us by supporting the Naked Scientists…

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Poolside launches Project Horizon: 2GW of AI compute 4:06

10d ago4:06

4:06

Integrating across compute, power, and intelligence.

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Warm Up Right For Your Triathlon Workouts 56:22

22d ago56:22

56:22

Every TriDot workout includes a built-in warm-up, but are you actually doing it? This week, Vanessa is joined by Coaches Brady Hoover and Brandy Ramirez to discover why warming up is essential before every session. They’ll break down how to properly incorporate warm-ups into your TriDot training, share practical tips for swimming, biking, and runni…

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20VC: Sequoia's David Cahn on The Winners and Losers in AI | The $0-$100M Revenue Club: Is Triple, Triple, Double, Double Dead? | The Future of Defence: Who Wins and Who Loses | How to Analyse Margins ... 1:14:23

25d ago1:14:23

1:14:23

David Cahn is a Partner at Sequoia Capital and one of the world's leading AI investors. At Sequoia David has led investments in Clay, Juicebox, Sesame, Kela, Stark, etc.. Before Sequoia, David was a General Partner @ Coatue where he led investments in Notion and Hugging Face. AGENDA: 00:00 We Are in an AI Bubble 05:04 Why Building Physical Data Cen…

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20Growth: How to Build a Paid Marketing Machine: ROAS (Return on Ad Spend) 101 | The Rise of User Generated Content and How to Use It | TikTok Ads: Expectations vs. Reality | Hiring for Growth: When and ... 1:16:18

27d ago1:16:18

1:16:18

Sandy Diao is one of the most exceptional growth leaders of the last decade. Sandy has scaled products to over 200M+ users and led growth teams at Descript, Meta and Pinterest. She is also a prolific writer all on things growth here. AGENDA: 03:59 Biggest Growth Lessons from Pinterest 08:01 What is a Good vs a Bad Growth Hypothesis 11:11 Common Mis…

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Eye implant restores vision, and corvids follow human calls 34:44

17d ago34:44

34:44

In the news podcast, a new retinal implant - just two millimetres wide - that is helping restore sight to blind people; a 'pristine' star that gives us a glimpse of the workings of the early Universe; and we'll be finding out how wild rooks can master human commands. Like this podcast? Please help us by supporting the Naked Scientists…

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The contagious buzz of bumble bee positivity, and when snow crabs vanish 27:13

25d ago27:13

27:13

First up on the podcast, the Bering Sea’s snow crabs are bouncing back after a 50-billion-crab die-off in 2020, but scientists are racing to predict what’s going to happen to this important fishery. Contributing Correspondent Warren Cornwall joins host Sarah Crespi to discuss what’s next for snow crabs. Next on the show, freelance producer Elah Fed…