Best Protein Engineering Podcasts (2025)

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Alexey Lugovskoy Shares Decades of Experience in Starting Out and Founding Companies 47:23

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16d ago47:23

47:23

August 12, 2025 | Diagonal Therapeutics founder and CEO Alexey Lugovskoy discusses the key lessons learned over his illustrious career, starting from his childhood in the Soviet Union to founding his own company, Diagonal Therapeutics. With host Tariq Ghayur, Lugovskoy shares insights gained from working with organizations of different sizes, takin…

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20VC: Anthropic's $10BN Round | Klarna's IPO Broken Down | Inside a16z's 72 Deal Seed Investment Machine | Martin Casado: Is Consensus Investing the Only Game | Why Satya is Chatting S*** on SaaS Apps ... 1:11:40

14h ago1:11:40

1:11:40

AGENDA: 00:00 – Marc Benioff vs Snowflake, Databricks & Palantir: Who Wins the Data Cloud War? 05:10 – Does Benioff Feel The Need to Buy AI Talent Like Zuck Is? 09:00 – What Salesforce has Learned From Palantir on Forward Deployed Engineers? 18:00 – Will SaaS apps disappear in an AI world? Why Satya is Chatting S*** 23:40 – Are SDRs really screwe…

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Hard Truths from a Lifetime of Training w/ Bryan Boorstein, Anders Varner, Doug Larson, and Travis Mash #812 59:48

1d ago59:48

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Bryan Boorstein has 24 years of training and over 13 years of coaching experience. A 3-time CrossFit Regional athlete and CrossFit Games coach, Bryan holds a Bachelor of Science from JMU (2006) and certifications in CrossFit L-2 and Mobility. As the owner and founder of Evolved Training Systems and Paragon Training Methods, he’s a trusted name in f…

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What can we do about hair loss? 36:32

2d ago36:32

36:32

In this edition of The Naked Scientists, we look at the science of hair, why we suffer hair loss, treatments that can slow hair loss, whether wigs are any good, and what happens during a hair transplant? Like this podcast? Please help us by supporting the Naked ScientistsBy The Naked Scientists

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20VC: Do Margins Matter in AI? | Is Defensibility Gone For Good? | Is Vertical SaaS Dead in a World of AI | What SaaS Rules Are BS and No Longer Apply in a World of AI | The Future of Venture: Why Chanel ... 1:21:03

4d ago1:21:03

1:21:03

Byron Deeter is a Partner at Bessemer Venture Partners, and one of the most renowned SaaS investors. Byron has led 19 unicorn investments, including IPO successes like ServiceTitan, Procore, Twilio, Box, Gainsight, Intercom, DocuSign, SendGrid. His portfolio includes eight companies that have gone public. Insane. Agenda: 00:00 – Why are the stakes …

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Physiology Friday: The Rhythm of Rest: Unlocking Sleep Potential Naturally w/ Dr. Chris Perry, Anders Varner, Doug Larson, and Travis Mash 54:16

6d ago54:16

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Dr. Christopher A. Perry, an Assistant Professor at Eastern Kentucky University, began his fitness journey at Penn State University, where he developed a robust background in Strength & Conditioning leading to 17 years in the industry to date. His academic path, leading through a PhD at Arizona State University, deepened his expertise in Exercise S…

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Apple wins privacy row, and microbes dictate chocolate taste 34:40

6d ago34:40

34:40

In this edition of The Naked Scientists, Apple locked horns with the UK government who were demanding a security back door through the company's encryption. What was the outcome? Also, scientists discover the secret to the tastiest chocolate - it's all down to microbes. And, archaeologists uncover the earliest evidence yet of our ancestors using st…

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20VC: Databricks at $100BN | Chamath’s SPAC Revival: Peak Mania? | OpenAI Staff Cash Out Billions & Sam Altman Will Spend Trillions | CoreWeave’s $11B Debt Bet & Nubank’s $2.5B Profit Shocker 1:27:58

8d ago1:27:58

1:27:58

Agenda: 00:00 – Databricks hits $100B: Bubble or just the beginning? 03:15 – Is Databricks actually undervalued at 25x revenue? 07:40 – Are we on the verge of the biggest IPO wave ever? 11:30 – Can Andreessen’s Databricks bet return $30B+? 18:10 – Who really gets rich when mega-unicorns IPO? 19:30 – Is the return of Chamath’s SPACs the ultimate bub…

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Optical biosensors for neural circuits and methane-eating enzymes with Loren Looger 55:51

8d ago55:51

55:51

When Loren Looger walks into a room, he doesn't want recognition, he wants to make things that work. The creator of revolutionary, open-source tools that transformed how we visualize brain activity is increasingly turning his protein engineering expertise to formidable challenges in climate, including methane degradation. . Methane sits at the hear…

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The Truth About Energy Drinks w/ Flavia Pereira, Anders Varner, Doug Larson, and Travis Mash #811 47:06

8d ago47:06

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Flavia is a passionate CISSN nutrition coach, full-time Exercise & Sport Science faculty member, and beach volleyball strength & nutrition coach. She has been teaching and coaching for the past 18 years. She graduated with a B.S. and M.S. in Kinesiology - Exercise Science and is pursuing her Ph.D. in Health & Human Performance. Flavia is part of th…

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What Niger's AMR outbreak means for the world 31:03

9d ago31:03

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In this edition of The Naked Scientists, why we need to pay closer attention to antimicrobial resistance in some of the world's poorest nations... Like this podcast? Please help us by supporting the Naked ScientistsBy The Naked Scientists

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20VC: Lovable CEO Anton Osika on $120M in ARR in 7 Months | The Honest Truth About Defensibility and Unit Economics for AI Startups | The State of Foundation Models: Long Grok, Short OpenAI, Why | Replit ... 1:08:48

11d ago1:08:48

1:08:48

Anton Osika is the Co-Founder and CEO @ Lovable, the fastest growing company on the planet. In just 7 months, they have scaled from $0 to $120M in ARR. They have raised over $200M in funding from some of the best including Accel, Creandum and 20VC. Their latest round priced the company at a whopping $2BN. Agenda for Today: 00:00 – Is AI an Arms Rac…

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Physiology Friday: How to Build a Killer Cardiovascular System w/ Dr. Mike T. Nelson, Anders Varner, Doug Larson, and Travis Mash 52:24

13d ago52:24

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In today’s episode of Barbell Shrugged, Anders Varner, Doug Larson, and Travis sit down with Anders coach, Dr. Mike T. Nelson. For those that have followed the show, you know Anders has been in pursuit of running a sub-6 minute mile at the age of 40. Dr. Nelson is the coach Anders hired to help with that goal. In this episode the crew walks through…

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20VC: 15 Term Sheets in 7 Days and Choosing Benchmark | Harvey vs Legora: Who Wins Legal and How to Play When You Have $600M Less Funding | Are AI Models Plateauing Today | Building a 9-9-6 Culture From ... 1:20:48

13d ago1:20:48

1:20:48

Max Junestrand is the Co-Founder and CEO @ Legora, the collaborative AI powering the next generation of lawyers. Now this is an insane story for many reasons; first, Max turned down a multi-million dollar career in gaming to build Legora. Second, he has raised from the best of the best including Benchmark and IVP. Third, he has scaled the firm with…

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Decoding our inner voice, and hunting for life on Mars 36:35

13d ago36:35

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In this edition of The Naked Scientists: the scientists who think they can decode the thoughts we hear in our heads. Also ahead: do ultra-processed foods make it much harder to lose weight? Plus, we hear from the PhD student who is aiding the search for life on Mars... Like this podcast? Please help us by supporting the Naked Scientists…

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20VC: GPT5: Sam Altman's Masterplan or a Gift To Anthropic | Palantir & Shopify Crush Earnings | Monday & Datadog Perform But Hit Hard by Wall St | Should Perplexity Buy Chrome for $34.5BN | 1:22:01

14d ago1:22:01

1:22:01

AGENDA: 00:04 – Was GPT-5 the Biggest AI Letdown Yet? 00:17 – Is OpenAI’s Real Target Anthropic’s $6B Revenue? 00:22 – Why Anthropic Might Secretly Be Worried 00:28 – The Hidden Business Strategy Behind OpenAI’s “Underwhelming” Launch 00:32 – Should Perplexity Really Try to Buy Chrome for $34.5B? 00:35 – The $3B N8N Deal: Genius Bet or Bubble FOMO?…

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When to Make Changes to Your Training w/ Anders Varner, Doug Larson, and Travis Mash #810 51:57

15d ago51:57

51:57

The crew breaks down how to know when it’s time to pivot your training. From bodybuilding and Olympic lifting to CrossFit, strongman, and martial arts, they share what decades under the bar have taught them about adapting for longevity, avoiding injury, and keeping fitness enjoyable. In this episode, you will learn: How to recognize when your train…

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'Three-parent babies' prevent inherited genetic condition 26:56

16d ago26:56

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James Tytko explores the science behind 'three-parent' embryos: the incredible medical procedure that prevents children from inheriting incurable mitochondrial diseases. Like this podcast? Please help us by supporting the Naked ScientistsBy The Naked Scientists

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20VC: Figma, Scale, Wiz: Inside Index's Decacorn Factory | Decision-Making, Investment Process, Biggest Lessons, Biggest Misses | Why Gross Margin is a Fallacy at Seed | Never Turn Down a Deal on Price ... 1:19:50

17d ago1:19:50

1:19:50

Martin Mignot is a Partner at Index Ventures, the best-performing fund in the world right now. In the last three months, they have sold Wiz for $ 32 billion, sold Scale for $14.9 billion, and IPO'd Figma as the largest investor. In addition to this, they are the largest or second-largest shareholders in Roblox, Revolut, Adyen and Datadog. Agenda fo…

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Physiology Friday: [Immune System] Why Optimal Nutrition Starts with the Immune System w/ Anders Varner, Doug Larson, Coach Travis Mash and Dan Garner 56:46

20d ago56:46

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In this Episode of Barbell Shrugged: What is the immune system Why the immune system is responsible for building muscle How gut health impacts the immune system Understanding recovery and its impact on the immune system How to optimize your immune system for performance Visit https://rapidhealthoptimization.com Connect with our guests: Anders Varne…

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Medicinal microbes for kidney stones, and musky mice 31:24

20d ago31:24

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In the news, why a dose of bacteria might be the solution to combating kidney stones. What tooth enamel tells us about the lives and diets of dinosaurs. And what the world's most abundant insects can teach robots... Like this podcast? Please help us by supporting the Naked ScientistsBy The Naked Scientists

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20VC: The $BN Greenoaks Backed Protein Bar | Hitting $100M Revenues in David's First Year: Lessons & Mistakes | $0 to $600M: The Untold RXBAR Story | Product-Market-Fit, Pricing, Branding: What Every Founder ... 1:06:15

21d ago1:06:15

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Peter Rahal is the Co‑Founder & CEO of David Protein, the highest protein‑to‑calorie ratio for any protein bar on the market. Peter has raised over $85M from Greenoaks, Dr. Peter Attia and Dr. Andrew Huberman with the latest round valuing the company at $725 million. The company is poised for over $100 million in first‑year revenue. Formerly, Peter…

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20VC: Figma's 250% Pop - The Greatest IPO Mispricing Ever | Meta and Microsoft Blowout Quarters: Broken Down | Cognition Raises at $15BN and Ramp at $22BN | CRV Downsizing and What It Means for LPs and ... 1:20:30

22d ago1:20:30

1:20:30

Agenda: 00:00 – The Worst IPO Mis-Pricing Ever: What Really Happened at Figma 02:30 – Fidelity vs Founders: How Important is Fidelity When Going Public 07:00 – Why Founders Secretly Want a Pop, Even If It Makes Them Look Stupid 10:15 – The Truth Behind the $3B Figma "Left on the Table" 14:00 – Direct Listings vs IPOs: Should Figma Have Gone Direct …

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Protein and Amino Acids to Become Combat Ready w/ Dr Jess Gwin, Anders Varner, Doug Larson, and Travis Mash #809 53:46

22d ago53:46

53:46

Dr. Jess Gwin is a PhD in Nutritional Science and post-doctoral fellowship focused on muscle physiology and protein metabolism. Researcher in protein/essential amino acids (EAAs) nutrition, muscle preservation, and energy deficiency. Advocate for using data-driven nutrition to extend health span and performance. Work With Us: Arétē by RAPID Health …

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A 21st century guide to hunting dinosaur fossils 33:05

23d ago33:05

33:05

In this edition of The Naked Scientists, we are on the hunt for dinosaurs as we explore how cutting edge tech, chisels, and canoes go hand in hand when changing the way we view our prehistoric past... Like this podcast? Please help us by supporting the Naked ScientistsBy The Naked Scientists

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20Sales: $0-$3.7BN: The Databricks CRO’s Playbook to Build the Fastest GTM Engine in SaaS History | How Databricks Beat Snowflake | How To Build a Sales Org of 5,000 and Close $190M Deals with Ron Gabrisko ... 1:15:36

24d ago1:15:36

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Ron Gabrisko is the Chief Revenue Officer at Databricks, where he joined in 2016. Under his leadership, Databricks has scaled from $0 to $3.7BN annualized revenue. He has grown the sales team from 0 to over 1,000 globally, leading expansion into enterprise, government, and international markets. Ron previously held senior sales roles at Cloudera an…

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20VC: Inside Carnegie Mellon's $4BN Endowment | Why 90% of LPs Shouldn't Invest in VC | The $140BN Problem with Multi-Stage Funds | The Hidden Math Behind DPI, TVPI, and Illiquidity with Miles Dieffenbach ... 1:27:17

25d ago1:27:17

1:27:17

Miles Dieffenbach is Managing Director of Investments at Carnegie Mellon University, where he helps oversee a $4 billion endowment with a focus on venture capital, private equity, and alternative investments. Under his leadership, CMU’s private book has remained self-funding during some of the toughest years for liquidity. Agenda for Today: 00:04 –…

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Physiology Friday: [Blood Sugar] The Most Optimal Way to Control Blood Sugar w/ Anders Varner, Doug Larson, Coach Travis Mash and Dan Garner 58:46

27d ago58:46

58:46

In this Episode of Barbell Shrugged: What to look for in lab work about your glucose levels What Doctors will not tell you about your glucose levels How to know if you are pre-pre-diabetic Why normal range for your glucose levels could be a bad thing How to regulate blood glucose and why it is important Connect with our guests: Anders Varner on Ins…

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Old drug new tricks, and a sensational bionic leg 31:53

27d ago31:53

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In the news, an old drug heralds a new treatment for the gut parasite Cryptosporidium; the bionic-knee that anticipates where amputees want to go to make movements much more natural; and why we're spotting more Near-Earth Objects, and whether one may hit us. Like this podcast? Please help us by supporting the Naked Scientists…

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Episode 185: Andrew Koutnik discusses metabolic health, athletic performance and growing up with type-1 diabetes 1:31:37

28d ago1:31:37

1:31:37

Today we have our good friend and colleague Dr. Andrew Koutnik on the show. Andrew is a research scientist who studies the influence of nutrition and metabolism on health, disease and performance. He specializes in Type 1 diabetes and works with a wide range of people to improve their metabolic health and athletic performance. Andrew is a visiting …

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20VC: Benchmark Loses Another Partner | Elad Gil Raises a Monster $1.5BN Solo GP Fund | Why Apple Need a Management Overhaul | Why Google is the Best Performing Hyperscaler | Will Cursor Hit $4BN ARR ... 1:21:26

29d ago1:21:26

1:21:26

Agenda: 00:00 - Why Benchmark Is Bleeding Partners (and Why That’s the New Normal) 04:57 - “I Wouldn’t Leave Benchmark… Unless I Had THIS” — Jason on Brand vs Autonomy 09:01 - The Rise of the Solo GP & The Death of LP Conventional Wisdom 13:50 - The Unstoppable Force of Elad Gil & The Myth of LP Discipline 18:45 - Is Vibe Coding the New SaaS? Jason…

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Episode: 75 - Are Licensing Fees Required or Gatekeeping? 32:30

1M ago32:30

32:30

July 15, 2025 | Are licensing fees required or gatekeeping? In this episode of The Chain, host Nimish Gera, vice president of Biologics at Mythic Therapeutics, and Ian Wilkinson, CEO of Gamma Proteins, discuss accessing antibody discovery technology through licensing fees and royalties—and whether these fees are justified or not. Wilkinson delves i…

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The science of modern warfare 30:08

1M ago30:08

30:08

In this edition of The Naked Scientists, how is science helping to shape the future of warfare? Like this podcast? Please help us by supporting the Naked ScientistsBy The Naked Scientists

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20VC: a16z's Martin Casado on Anthropic vs OpenAI: Where Value Accrues | Cursor vs Replit vs Lovable: Who Wins and Who Loses | The One Sin in AI Investing | Why Open Source is a National Security Risk ... 1:10:37

1M ago1:10:37

1:10:37

Martin Casado is a General Partner @ a16z where he leads the firms $1.25BN infrastructure fund. At a16z, Martin has led investments in companies like Cursor, dbt Labs, and Fivetran to name a few. Before joining a16z, he co-founded Nicira, acquired by VMware for $1.26B. At VMware, he served as CTO of Networking. Widely regarded as a visionary in ent…

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20Product: Should We Kill the PM Role Entirely | How Does Product Design Change Most in a World of AI | How Do Monzo Build Product Today: What Works, What Does Not | Why Most Product Sucks and What Makes ... 1:07:26

1M ago1:07:26

1:07:26

Fernando Fanton is one of the most respected product leaders in Europe, having held Chief Product Officer roles at Monzo and Just Eat. He previously led product and tech at Rappi, one of Latin America's most valuable startups. Today, Fernando is the CPO @ Property Finder; one of the biggest breakout unicorns from MENA. Agenda: 00:00 – Is “having a …

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Physiology Friday: [Gut Health] The Epicenter of Health Optimization w/ Anders Varner, Doug Larson, Coach Travis Mash and Dan Garner Barbell Shrugged 45:23

1M ago45:23

45:23

In this Episode of Barbell Shrugged: Why the gut is so important for optimal health. What causes poor gut health and how to avoid it How important is a stool sample to find potential hidden stressors What your poop can tell you about your health Ways to improve gut health https://rapidhealthoptimization.com Connect with our guests: Anders Varner on…

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Malaria bites back, and the lunar base race 38:27

1M ago38:27

38:27

In the news podcast, what's causing the uptick in malaria cases in Africa? Also, scientists show statistically that the sex of a baby at birth is not random, and South Korea joins the throng in the race for settling on the Moon. Then, we hear how computer scientists are programming ethical AI to explain its decision making, and, sticking with AI, w…

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Redirecting the Microbiome: Rethinking Copper Mining with Sasha Milshteyn 47:09

1M ago47:09

47:09

What happens when a structural biochemist turns his attention to mountains of rock? Dr. Sasha Milshteyn takes us on a remarkable journey from studying tiny molecular movements in proteins to revolutionizing how we extract copper from massive mine heaps. The mining industry faces a critical challenge - we've depleted most easily-processed oxide copp…

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20VC: Lovable Raises at $2BN & Hits $100M ARR | Is Cursor Worth $28BN at $1BN in ARR | How Do All Providers Deal with Anthropic Dependency Risk | Are Seed Funds F******: Have Mega Funds Won | Figma IPO ... 1:21:38

1M ago1:21:38

1:21:38

Agenda: 00:00 – Did Jason Just Kill Replit? 03:45 – Why Claude Lies To You and Cannot Be Trusted 06:50 – You Cannot Trust Agents. Period. 10:20 – Why Windsurf Was Dead Without Claude 12:30 – Cursor vs. Lovable: What’s the Better Bet? 14:40 – Should You Still Invest in Cursor at $28B? 18:05 – Would You Bet on Anthropic at $100B or OpenAI at $300B? 2…

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SORINEX: LEGENDARY STRENGTH TRAINING W/ BERT SORIN, ANDERS VARNER, DOUG LARSON, AND COACH TRAVIS MASH BARBELL SHRUGGED #592 2:17:52

1M ago2:17:52

2:17:52

Bert and his wonderful wife Lesley are the proud parents of three children. Bert and his family, a family rooted in strength, have been entrenched in the human performance world for as far back as he can remember. Growing up with a barbell in his hand has been pivotal in charting the course of his life and leading him to become a 4-time Division 1 …

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Vivaldi: The data revolution coming to care homes 30:11

1M ago30:11

30:11

There are more than sixteen thousand care homes across the UK, housing around half a million people. Staggering numbers. They are meant to be places of safety, support, and quiet, relaxed companionship for the people who live and work in them. But when COVID-19 arrived, they became one of the pandemic's deadliest frontlines. In a bid to see what mi…

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20VC: Scaling to $1BN+ in Revenue with No Funding: Surge AI | The Most Insane Scaling Story in Tech | 1:06:20

1M ago1:06:20

1:06:20

Edwin Chen is the Founder and CEO of Surge. Founded in 2020, Surge has scaled to $1BN+ in revenue with zero external funding. At the same time, their competitor, Scale.ai raised over $1.3BN to reach $850M ARR. Today, Surge have the world’s largest model providers as customers and have just 120 employees. Agenda: 00:00 — “Everyone Else Is Just a Bod…

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20VC: Cognition CEO Scott Wu on Acquiring Windsurf: The Process, The Deal, The Rationale | Did Google Overlook a Goldmine in the Core Asset and Did Founders Leave a Sinking Ship | How Cursor and Cognition ... 48:08

1M ago48:08

48:08

Scott Wu is the co-founder and CEO of Cognition, the company behind Devin, the world’s first AI software engineer. On Friday last week they pulled off the acquisition of the year, acquiring Windsurf, following their licensing agreement with Google. Previously a world-class competitive programmer, he was a gold medalist at the International Olympiad…

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Ancient Antarctic ice cores & is a sense of humour genetic? 40:23

1M ago40:23

40:23

In this edition of The Naked Scientists: Scientists get their hands on the oldest ice on Earth, and we've been to see it, but what's it going to reveal? Also, measles is on the up, again; we find out why. And, is humour genetic? We talk to the scientist who has studied hundreds of pairs of twins to find out! Like this podcast? Please help us by sup…

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20VC: Windsurf x Google x Cognition: Full Breakdown: Who Made Money, Who Did Not | Lovable vs Replit: Will These Be $100BN Businesses | Why Elon Could Beat Sam Altman with the New Grok | Why Every S&P ... 1:21:58

1M ago1:21:58

1:21:58

Agenda: 00:00 Windsurf was dead—then this deal changed everything 05:00 The Windsurf x Google x Cognition saga explained 09:00 The OpenAI deal collapsed—what really happened 15:00 FTC rules forced a brutal deal structure—who lost? 17:00 The investors’ returns: who actually made money? 21:30 Will Google’s corp dev team get fired over this? 23:00 Cog…

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How Travis Mash Got a 6-Pack at 50 Years Old w/ Anders Varner, Doug Larson, and Travis Mash #807 56:24

1M ago56:24

56:24

The home team is back again and Travis Mash has been posting too many shirtless selfies with all the abs for us not address the nutrition, fitness, and training programs he is up to. Tons of insight into getting back to the basics, simplifying, and making it all work while keeping family at the center of it all. Enjoy. Work With Us: Arétē by RAPID …

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25 years of the Human Genome Project 31:18

1M ago31:18

31:18

In this edition of The Naked Scientists, we look at 25 years of the Human Genome Project. What is it? And what has it achieved? Like this podcast? Please help us by supporting the Naked ScientistsBy The Naked Scientists

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20VC: Vlad Tenev on Robinhood’s $85BN Resurgence | Tokenizing SpaceX & OpenAI | Building Nine Revenue Lines Over $100M | Why Crypto Will Be Robinhood's Biggest Revenue Line | Why Stablecoins Will Replace ... 57:52

2M ago57:52

57:52

Vlad Tenev is the Founder and CEO of Robinhood, the greatest story on Wall St of the last decade. In the previous 18 months, Robinhood has increased its net revenue by 58% to nearly $3B; a $500M loss in 2023 turned into a $1.1B profit in 2024. Robinhood’s stock is up roughly 4x, lifting their market cap to north of $80B. Today, Robinhood has nine l…

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20Growth: The Death of Growth Teams? | How Hubspot Use AI to Triple Email Conversion | The Future of AI SEO | Why Prompt Engineering is the New Coding | What Every CMO Needs to Know About AI in 2025 1:15:51

2M ago1:15:51

1:15:51

Kieran Flanagan is the CMO at HubSpot, where he’s led the transformation of their growth strategy from SEO-led to multi-channel and AI-powered. Formerly SVP of Marketing, he helped scale HubSpot’s user base to millions and revenue past $2B. Before HubSpot, he drove breakout growth at Marketo and Salesforce. Kieran is one of the most respected voice…