Conversations with scientists at the forefront of brain research. Hosted by neuroscientist Mark Mattson.
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Mark Mattson Podcasts
A podcast about health, science, nutrition, aging, and fitness.
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We’re a team of doctors with a combined 100 years of experience and a passion for helping patients find long-term vitality using our new approach to medicine. Instead of just trying to lengthen your lifespan, we aim to lengthen your healthspan.
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Welcome to Brain Fit, the podcast dedicated to empowering you to protect your brain and enhance cognitive health. Hosted by Dr. Robert Love, a neuroscientist with a passion for Alzheimer's prevention, this show offers science-backed strategies to help you and your loved ones safeguard your minds for the future. Each episode features cutting-edge research and insights from leading experts in neuroscience, health, and wellness. Dr. Love dives into essential topics such as the role of diet, exe ...
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Welcome to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, the transformative podcast that delves into the root causes of cognitive decline and provides real solutions for preventing—and even reversing—Alzheimer’s. Hosted by Dr. Josh Helman, MD, a Harvard-trained physician with advanced degrees in biochemistry, this show is designed for individuals living with Alzheimer’s, their loved ones, and anyone determined to preserve and improve brain health. Each week, Dr. Josh demystifies the com ...
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“Scaling Clean" is an insightful podcast for cleantech CEOs, investors and the people who advise them. Each show, host Mike Casey brings you a deeper look into the minds of influential leaders working to create a new clean economy.
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In a world brimming with groundbreaking discoveries and technological advancements in medicine and science, equitable access to life-saving cures and treatments remains a pressing concern. Join us on a riveting journey through my podcast series, where we delve into the heart of pioneering research, innovative breakthroughs, and the tireless efforts of scientists and doctors to make healthcare accessible and affordable for all. Through thought-provoking conversations with leading experts, pas ...
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A zany, scripted, dark comedy that explores the bystander effect - a social psychological theory that states individuals are less likely to offer help to a victim when in the presence of other people. Every season - new story, new Bystanders. Created by: Ash Lendzion and Jaclyn Hales Executive Produced by: Black Label Media, Heather Morris, Ash Lendzion, Jaclyn Hales, Nick Blair Wilfong, and Marilee Stafford Directed by: Jaclyn Hales and Ash Lendzion Written by: Jaclyn Hales, Ash Lendzion, N ...
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#65 - Dr. Mark Mattson | Neuroscience, Intermittent Fasting, and Brain Health
1:06:48
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1:06:48Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they interview Dr. Mark Mattson, one of the world’s leading neuroscientists and a pioneer in the study of aging, brain health, and neurodegenerative diseases. Dr. Mattson is Chief of the Laboratory of Neurosciences at the National Institute on Aging and Professor of Neuroscience…
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Can Skipping Meals Prevent Alzheimer’s? Dr. Mark Mattson’s Groundbreaking Research
1:13:08
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1:13:08What if skipping a meal could help save your brain? In this episode, Dr. Mark Mattson and I discuss the fascinating world of intermittent fasting. We explore cutting-edge science and groundbreaking research that shows how intermittent fasting can not only prevent Alzheimer’s but may also reverse its effects. Dr. Mattson, a neuroscientist and a lead…
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This Neurotransmitter Could be Causing Alzheimer's with Dr. Mark Mattson
1:40:47
1:40:47
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1:40:47Could a single neurotransmitter be fueling the progression of Alzheimer's? Dr. Mark Mattson, a leading expert on Alzheimer's, joins me to explore the groundbreaking research that reveals how this often-overlooked molecule may be impacting your brain health and what you can do about it. Dr. Mattson shares his insights on how neurotransmitter imbalan…
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Marian Joëls and Ron de Kloet: How the Brain Responds to Stress in Health and Mental Disorders
1:14:54
1:14:54
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1:14:54In stressful situations the brain communicates with the adrenal glands stimulating them to release adrenaline and cortisol. This stress responsive neuroendocrine system plays important adaptive roles by regulating energy metabolism, attention, and learning and memory. However, without a recovery period chronic uncontrolled stress such as psychosoci…
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The Power of Fasting with Dr. David Jockers
48:18
48:18
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48:18Did you know fasting could be the key to preventing Alzheimer's and boosting brain function? In this episode, I interview Dr. David Jockers, a world-renowned expert in natural medicine and brain health. We discuss the powerful benefits of fasting, ketosis, and mitochondrial health. Dr. Jockers explains how fasting triggers autophagy, enabling the b…
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How Spike Protein May Accelerate Alzheimer’s & Cognitive Decline | Dr. Mobeen Syed
1:27:36
1:27:36
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1:27:36Could spike protein be the hidden culprit behind brain fog, cognitive decline, and even Alzheimer's disease? Dr. Mobeen Syed (also called Dr. Mobeen or DrBeen) joins me to discuss the concerning persistence of the spike protein in the body and its potential to accelerate the progression of neurodegenerative conditions. In this thought-provoking con…
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Getting Started Preventing Alzheimer's with Dr. Josh Helman
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39:36Alzheimer’s doesn’t have to be a one-way road. Dr. Josh Helman, my partner at Brain Power Clinics and a Harvard-trained physician, reveals why conventional medicine often fails patients and what we’re doing differently. We talk about the hidden causes of memory loss that most neurologists overlook, including infections, toxins, heavy metals, mold, …
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Transforming Senior Living: Building Longevity Communities to Prevent Alzheimer’s With Ted Teele
53:51
53:51
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53:51Are you ready for a new perspective on aging and brain health? In this episode, I had the privilege of interviewing Ted Teele, the visionary behind longevity communities. We discuss the future of senior living, examining how his groundbreaking approach combines science, technology, and wellness to create environments that foster healthier, happier …
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Josh Helman: Multipronged Approaches for Preventing and Treating Alzheimer’s Dementia
59:38
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59:38Clearly demonstrated as being effective for cardiovascular disease, lifestyle medicine is becoming an important discipline for the prevention and treatment of age-related brain disorders including Alzheimer’s and Parkinson’s diseases. In this episode I talk with Dr. Josh Helman about his experience working with patients at lifestyle medicine center…
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Grace (Beth) Stutzmann: Pivotal Role for Calcium in Brain Aging and Alzheimer’s Disease
53:14
53:14
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53:14The calcium ion controls neuronal network activity, synapse function and synaptic plasticity, and is a fundamental mediator of learning and memory. With aging and much more so in Alzheimer’s disease the ability of neurons to properly regulate their intracellular calcium levels becomes compromised. Evidence from human and laboratory animal studies h…
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Boost Your Memory with Science – Dr. Daniel Schacter
49:22
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49:22Ever wonder why you forget things or how multitasking is affecting your memory? Dr. Daniel Schacter, a professor at Harvard University and a memory expert, uncovers the surprising science behind memory errors and shares actionable tips to enhance your brain health and reduce the risk of Alzheimer’s. Professor Schacter shares insights from his groun…
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Can Water Fasting Reverse Cognitive Decline? Loren Lockman’s Surprising Insights
1:03:07
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1:03:07What if the key to improving brain health lies in something as simple and powerful as silence and fasting? In today’s episode, I’m joined by Loren Lockman, an expert in water fasting, who’s helped thousands reverse chronic conditions by allowing their bodies to heal naturally. Loren shares his journey of overcoming chronic illness with fasting, rev…
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Andrew Dillin – Stress and Aging: Mitochondria are Hubs of Information Flow in and Between Cells
49:00
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49:00Long believed to function only as the cell’s powerhouse research is revealing that mitochondria actively control a cell’s response to various types of stress. Even more amazingly mitochondria send stress-related signals between cells. In this episode UC Berkeley Professor Andy Dillin has made major advances in understanding basic mechanisms of agin…
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The Medical Doctor Silenced for Reversing Alzheimer's with Dr. Robert Hedaya
1:29:55
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1:29:55What if everything you know about Alzheimer’s treatment is wrong? Dr. Robert Hedaya, a psychiatrist and physician who reversed Alzheimer’s, reveals how his revolutionary approach was silenced by the very institutions meant to protect patients. In this eye-opening episode, Dr. Hedaya joins me to discuss how his functional medicine approach to Alzhei…
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Fasting to Prevent Alzheimer’s? Dr. Valter Longo’s Shocking Findings
51:07
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51:07Can fasting and food timing hold the key to preventing Alzheimer's? In today's episode, I'm joined by Dr. Valter Longo, a pioneer in the field of fasting and longevity science and founder of The Create Cures Foundation. He is a biochemist and longevity researcher who leads groundbreaking work on aging, fasting-mimicking diets (FMD), and disease pre…
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Marc Freeman – How Astrocytes Control Neural Circuits in Brain Development, Plasticity, and Disease
1:18:41
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1:18:41While neurons and the circuits the form have been the major focus of brain research the human brain contains at least as many cells that are not neurons of which astrocytes are by far the most abundant. During the past decade there have been numerous studies that reveal novel and very active roles for astrocytes in regulating the growth of neurons,…
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Episode 3 of Scaling Clean features Mark Bassett, former CEO of Hemlock Semiconductor. With a Ph.D. in Chemical Engineering and a career spanning Dow Chemical and Hemlock, Mark shares insights on leading technical manufacturing companies, including driving sales growth during the COVID recession. About Tigercomm Tigercomm is top U.S. marketing comm…
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In this episode of Scaling Clean, we talk with Chad Farrell, CEO of Encore Renewable Energy. Unlike our previous guests, Chad is leading his first company — one he founded nearly 15 years ago. Encore develops community‑scale renewable energy projects, often on reclaimed industrial land, giving Chad unique lessons to share with first‑time cleantech …
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Episode 2 of Scaling Clean features Robert E. Fishman, veteran CEO of three energy companies with experience in renewables, fossil fuels, and nuclear. Bob shares thoughtful insights on leadership and offers valuable lessons on assembling and maintaining strong executive teams. About Tigercomm: Tigercomm is top U.S. cleantech PR firm agency helping …
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In this episode of Scaling Clean, we’re joined by Brad Mattson — often called a ‘Silicon Valley Legend’ for taking two companies from garage startups to Nasdaq. He’s also been a VC and led two clean economy companies, bringing decades of wisdom to our conversation. About Tigercomm Tigercomm is top U.S. marketing communications and public affairs fi…
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In this episode of Scaling Clean, we’re joined by Abby Hopper, President and CEO of the Solar Energy Industries Association (SEIA). A lawyer by training and veteran of major regulatory roles, Abby has led SEIA through pivotal years for the U.S. solar industry and brings unique insights on guiding teams through complex challenges. View transcript: h…
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Do you love eating out? Be cautious, as your favorite dish may be harmful to your brain. What food could this be? This is one of the questions that I answer in my second Ask Me Anything episode. Today, I’m addressing your pressing questions on a range of topics, from MCT oil to brain health and the risks associated with certain food types. First, w…
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Reverse Your Brain Age? The New Test That Could Prevent Alzheimer’s With Dr. Christin Glorioso
56:01
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56:01What if you could know the age of your brain today and take action to reverse it? In this episode, I interview Dr. Christin Glorioso, CEO and co-founder of NeuroAge Therapeutics, who reveals how we can now track and reverse brain aging, even before Alzheimer’s symptoms appear. You won't want to miss her insights into groundbreaking technologies, in…
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Polina Shichkova: Metabolic and Biophysical Modeling of Breakdown and Repair of the Aging Brain
1:03:05
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1:03:05Because neurons in the brain are electrically excitable and active 24/7 the brain consumes relatively large amounts of energy and must adapt to varying demands on its neural networks. The cellular and molecular complexity of the brain presents a major challenge for understanding not only its second-by-second function but also how neural networks ar…
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Preventing Chronic Disease with Food – Dr. Joel Fuhrman Explains
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52:37Did you know that a plant-rich, nutrient-dense diet can not only prevent chronic diseases like Alzheimer's but also enhance our mental clarity and overall well-being? In this episode, I speak with Dr. Joel Fuhrman, a leading physician in the field of nutritional medicine. Dr. Fuhrman reveals how diet plays a crucial role in preventing and even reve…
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How Insulin Resistance Impacts Alzheimer’s: Insights From Dr. Yousef Elyaman
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52:00What if the root cause of Alzheimer's isn't just in the brain? Discover how insulin resistance, toxins, and inflammation are silently linked to cognitive decline and how a holistic approach could offer hope for prevention and reversal. In this episode, I had the privilege of interviewing Dr. Yousef Elyaman, a double board-certified physician, about…
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Corinde Wiers: The Potential of Ketone-Based Interventions for the Treatment of Addiction
1:07:26
1:07:26
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1:07:26Research on substance use disorders has largely focused on understanding the key neural circuits and neurotransmitter systems that are altered, and on behavioral and pharmacological interventions. However, emerging research findings suggest that alcohol use disorder (AUD) is associated with alterations in energy metabolism and can accelerate brain …
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#64 - Dr. Yanina Pepino | The Neuroscience of Taste, Sweeteners, and Metabolic Health
1:28:24
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1:28:24Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they interview Dr. Yanina Pepino, a renowned professor of Ingestive Behavior at the University of Illinois. With a background in medicine and a research trajectory that spans Washington University’s Center for Human Nutrition to her current work in sensory biology, Dr. Pepino br…
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#104 Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, & Sleep
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3:01:02Get access to 130 episodes of my premium podcast, The Aliquot, as a FoundMyFitness Premium Member Insulin resistance silently shapes the trajectory of nearly every major chronic disease, yet it's often overlooked until blood sugar abnormalities become obvious. In this episode, Dr. Ben Bikman exposes the dietary culprits that drive metabolic dysfunc…
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You CAN Grow New Brain Cells With Dr. Brant Cortright
1:12:10
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1:12:10Did you know that you can grow new brain cells as an adult? In this episode, Dr. Brant Cortright, author of The Neurogenesis Diet and Lifestyle, joins me to share cutting-edge insights on how diet, lifestyle, and natural supplements can help stimulate the growth of new brain cells and enhance brain health. Dr. Cortright reveals that the brain is ca…
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The Surprising Link Between Emotional Overload and Cognitive Decline With Alex Howard
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38:00Did you know that trauma might be at the root of chronic conditions like Alzheimer’s? In today’s episode, I sit down with Alex Howard, founder of The Optimum Health Clinic, to explore how emotional overload and childhood trauma contribute to cognitive decline and other chronic health issues. We dive into Alex's healing journey and how his personal …
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Henning Fenselau – Neural Circuits Controlling Appetite and Energy Metabolism and GLP-1 Actions
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56:52Appetite (hunger and satiety) is controlled by neural circuits in the brain – particularly in the hypothalamus – and their reciprocal connections to peripheral organs involved in energy metabolism (gut and liver). Understanding the structural organization of these circuits (their synaptic connections) and their neurochemistry (particularly which ne…
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The Power of Sleep With Dr. Michael Breus
1:23:42
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1:23:42Are you struggling with sleep issues? You're not alone. In this episode, I sit down with Dr. Michael Breus, one of the world's leading sleep experts, to explore the profound impact sleep has on our brain health. From chronotypes to sleep hygiene, you'll learn actionable tips that can transform your sleep and improve your memory, especially if you'r…
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The Diet That Helped Reverse Schizophrenia: Daniel Helman on Mental Health Recovery
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1:13:38Living with a mental health challenge can make everyday tasks feel overwhelming, turning even the simplest things into struggles that others may not fully understand. Whether you're facing it yourself or supporting a loved one, the weight of these challenges can make life harder in ways that aren’t always visible. Sometimes you wonder if there's ho…
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#63 - Dr. Dominic D'Agostino | Advancing Metabolic Therapies Through Ketosis and Resilience Research
1:11:35
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1:11:35Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they speak with Dr. Dominic D’Agostino, Associate Professor at the University of South Florida and research scientist at the Institute for Human and Machine Cognition (IHMC). Renowned for his work on metabolic therapies, Dr. D’Agostino has led pioneering research into how nutrit…
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Tessa Montague: Disappearing Act - How the Brain Controls Camouflage in Cuttlefish and Octopuses
1:09:01
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1:09:01One of the most remarkable feats of biological ‘wizardry’ in the animal kingdom is the ability of some cephalopods (octopuses, squids, and cuttlefish) to rapidly change the color, patterning, and texture of their skin so as to blend in with their background. They accomplish these feats through the linking of neural circuits in the visual system and…
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Are you struggling with sleep, brain fog, or memory loss? Do you have some burning questions about your health? Today, I'm hosting a Q&A episode where I answer some frequently asked questions. From tackling poor sleep to managing ADHD symptoms, I offer science-backed solutions that are simple and effective, allowing you to implement them today. I c…
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Stop Cognitive Decline: Jane Thurnell-Read’s Healthy Aging Secrets
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50:20Are you ready to embrace aging with vitality? In today’s episode, I had the privilege of sitting down with Jane Thurnell-Read, a passionate advocate for healthy aging, plant-based living, and brain health. Jane, an author and self-described “aging optimist,” shares her incredible journey to living a long and healthy life without relying on medicati…
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Jonathan Long: Lactate-Phe and Ketone-Phe: Exerkines and Fastokines for Brain Health and Plasticity?
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1:02:26During vigorous exercise lactic acid (lactate) levels increase in the blood and during fasting and extended exercise the levels of the ketone BHB (b-hydroxybutyrate) increase. In this episode I talk with Stanford University professor Jonathan Long about his recent discovery that lactate and BHB in the blood are bound to the amino acid phenylalanine…
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The Gut-Brain Connection With Dr. Steven Gundry
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32:14What if fixing your gut could actually reverse your risk of developing Alzheimer’s? Today, renowned cardiologist and bestselling author Dr. Steven Gundry joins me for another enlightening conversation. Dr. Gundry has spent decades uncovering the connection between gut health and brain function, and he shares his groundbreaking insights on how what …
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The Fascia Therapy Transforming Brain Health & Concussion Recovery With Deanna Hansen
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52:24Have you ever wondered how something as simple as fascia decompression—a technique that involves releasing tension in the connective tissue surrounding the muscles—could be the key to improving brain health? In this episode, Block Therapy creator Deanna Hansen joins me to explore how this therapy can aid in concussion recovery, Alzheimer’s preventi…
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Carlos Matute: Brain White Matter in Health, Endurance Exercise, and Disease
1:17:20
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1:17:20White matter consists of bundles of long axons that convey information between neural circuits between different brain regions within and between brain hemispheres. These long axons are wrapped with many layers of lipid-rich membranes of oligodendrocytes (a type of glial cell) and it is this ‘insulation’ that enables rapid propagation of signals ov…
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#62 - Dr. Jens Juul Holst | Discovering the Hormone That Changed Metabolic Medicine
1:04:38
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1:04:38Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they speak with Dr. Jens Juul Holst, the renowned Danish physiologist and co-discoverer of GLP-1 (glucagon-like peptide-1), one of the most significant hormones in metabolic disease research. A professor of medical physiology at the University of Copenhagen and former scientific…
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#103 A Deep Dive on Using Coffee For Health & Longevity (Full Guide & Research)
48:49
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48:49Get access to more than 120 episodes of my premium podcast, The Aliquot, as a FoundMyFitness Premium Member Coffee is one of the most powerful longevity tools we have, potentially reducing epigenetic age by up to one year in regular coffee drinkers, but its effectiveness hinges entirely on how you brew it. In this episode, I outline precisely how c…
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Preventing Alzheimer's With Dr. Josh Helman, MD
1:02:05
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1:02:05Are you ready to learn how to prevent and even reverse Alzheimer’s? I’m Robert Love, and in this episode, I speak with Dr. Josh Helman, a Harvard-trained physician at the forefront of Alzheimer’s prevention and reversal. Dr. Helman shares groundbreaking insights on the root causes of Alzheimer’s, including inflammation, poor sleep, and high blood s…
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How Autoimmune Diseases Could Be Fueling Alzheimer’s With Dr. Peter Rogers
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1:00:06Did you know that autoimmune diseases could affect your risk of developing Alzheimer's? In this episode, Dr. Peter Rogers, a Stanford and Harvard-educated physician, returns, and we dive deep into autoimmune diseases and their surprising connection to Alzheimer’s. He explains how autoimmune diseases can play a significant role in the development of…
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Michael Kreutz: Amazing Nanomachines in Synapses that Keep Brains Healthy and Wise
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1:01:28Michael Kreutz is Head of the Neuroplasticity Research Group at the Leibniz Institute for Neurobiology in Magdeburg Germany. Using powerful high resolution microscopy and molecular biology tools his laboratory has shown that autophagy occurs within synapses. Synaptic autophagy is stimulated by neural network activity and is critical for their maint…
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While average human life spans have increased due to better medical protocols, improved nutrition, and healthier lifestyles, it doesn't change the fact that we are all going to age. But what if aging were optional and you had the data to prove it? I’m Robert Love, and in this episode, I sit down with tech entrepreneur and Blueprint founder Bryan Jo…
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How Being Raw Vegan Reversed My Diabetes & Boosted Brain Health – FullyRaw Kristina
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1:08:27What if you could reverse type 2 diabetes and boost your brain health with nothing more than the food you eat? In today’s episode, I sit down with the inspiring Kristina Carrillo-Bucaram, also known as "FullyRaw Kristina," to discuss her remarkable journey from living with type 2 diabetes to achieving vibrant health through a raw vegan lifestyle. H…
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Jordan Grafman: Neural Circuits of Religiosity: ‘The Kingdom of God’ is in the Prefrontal Cortex
1:11:17
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1:11:17Belief in supernatural agents and other religious myths arose as a means of ‘explaining’ the unknown and as a tool for social cohesion and hierarchical control of civilizations. Their religiosity is major feature of a ‘believers’ self identity as well as their group identity. Compelling evidence from multiple types of studies have revealed the neur…
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