Conversations with scientists at the forefront of brain research. Hosted by neuroscientist Mark Mattson.
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Mark Mattson Podcasts
A podcast about health, science, nutrition, aging, and fitness.
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We’re a team of doctors with a combined 100 years of experience and a passion for helping patients find long-term vitality using our new approach to medicine. Instead of just trying to lengthen your lifespan, we aim to lengthen your healthspan.
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Welcome to Brain Fit, the podcast dedicated to empowering you to protect your brain and enhance cognitive health. Hosted by Dr. Robert Love, a neuroscientist with a passion for Alzheimer's prevention, this show offers science-backed strategies to help you and your loved ones safeguard your minds for the future. Each episode features cutting-edge research and insights from leading experts in neuroscience, health, and wellness. Dr. Love dives into essential topics such as the role of diet, exe ...
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Welcome to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, the transformative podcast that delves into the root causes of cognitive decline and provides real solutions for preventing—and even reversing—Alzheimer’s. Hosted by Dr. Josh Helman, MD, a Harvard-trained physician with advanced degrees in biochemistry, this show is designed for individuals living with Alzheimer’s, their loved ones, and anyone determined to preserve and improve brain health. Each week, Dr. Josh demystifies the com ...
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“Scaling Clean" is an insightful podcast for cleantech CEOs, investors and the people who advise them. Each show, host Mike Casey brings you a deeper look into the minds of influential leaders working to create a new clean economy.
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A zany, scripted, dark comedy that explores the bystander effect - a social psychological theory that states individuals are less likely to offer help to a victim when in the presence of other people. Every season - new story, new Bystanders. Created by: Ash Lendzion and Jaclyn Hales Executive Produced by: Black Label Media, Heather Morris, Ash Lendzion, Jaclyn Hales, Nick Blair Wilfong, and Marilee Stafford Directed by: Jaclyn Hales and Ash Lendzion Written by: Jaclyn Hales, Ash Lendzion, N ...
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In a world brimming with groundbreaking discoveries and technological advancements in medicine and science, equitable access to life-saving cures and treatments remains a pressing concern. Join us on a riveting journey through my podcast series, where we delve into the heart of pioneering research, innovative breakthroughs, and the tireless efforts of scientists and doctors to make healthcare accessible and affordable for all. Through thought-provoking conversations with leading experts, pas ...
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Does COVID Increase Alzheimer's? with Dr. Dale Bredesen, Part 2
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1:01:10Do you want to learn some practical steps to boost brain health and prevent Alzheimer’s? Today, I continue my conversation with Dr. Dale Bredesen, a leader in Alzheimer’s prevention and reversal. We explore the impact of COVID-19 on brain health and its contribution to cognitive decline. Dr. Bredesen explains the role of inflammation, particularly …
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Can Diet Reverse Alzheimer’s? Dr. Doug Graham on the 80/10/10 Raw Vegan Plan
1:17:03
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1:17:03What if the key to preventing or even reversing Alzheimer’s isn’t in a pill, but in what you put on your plate? In this episode, I interview Dr. Doug Graham, a raw food pioneer and creator of the 80/10/10 diet, to explore how a plant-based, low-fat, high-carbohydrate diet can transform brain health. We discuss real-life cases of patients whose Alzh…
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Media Lies and Alzheimer’s Disease with Dr. Dale Bredesen, Part 1
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1:00:14What if the truth about Alzheimer’s was being buried by the very outlets we trust? In this episode, I interview Dr. Dale Bredesen, the Chief Science Officer of Apollo Health and a world-renowned neurologist, whose groundbreaking work demonstrates that Alzheimer’s can be prevented and even reversed. We dive into the shocking story of how mainstream …
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Brain-Boosting Greens: How Sprouts, Microgreens & Juicing Can Help Prevent Alzheimer’s With John Kohler
1:06:42
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1:06:42We all know we should eat more greens, but did you know that the plants you grow and how you prepare them can be your secret weapon for boosting brain health? Today, I interview John Kohler, a pioneer in raw food, home gardening, and plant-based nutrition, to explore how growing and eating nutrient-dense plants can protect your brain and even help …
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Erik Musiek: Brain Cell Circadian Clock Proteins in Neuroplasticity, Aging, and Alzheimer’s Disease
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1:12:00Health depends upon proper regulation of circadian rhythms of cell and organ functions. Disruption of circadian rhythms has detrimental consequences for brain function and resilience and abnormal circadian rhythms are a common feature of Alzheimer’s disease. In this episode neurology professor Erik Musiek talks about the roles of specific circadian…
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Reversing the Root Cause of Aging with Dr. Sandra Kaufmann
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1:34:19What if you could slow down the aging process, protect your skin, and boost your brain function at the same time? In this episode, I interview Dr. Sandra Kaufmann, a longevity expert, to explore the science behind why our cells and skin age, and what we can do about it. Dr. Sandy breaks down her “seven tenets of aging” and explains how DNA damage, …
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Is Your Water Harming Your Brain? How Toxins in Tap Water Could Contribute to Alzheimer’s With Dr. Roy Speiser
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1:02:40We all know we need water to survive, but what if the very water we drink every day is silently contributing to brain diseases like Alzheimer’s? Toxins lurking in our tap water are often overlooked, but research shows that pollutants like PFAs, heavy metals, and fluoride can, in fact, affect our brain health. In this enlightening episode, I intervi…
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Georgia Hodes: Sex Differences in Responses to Stress and Vulnerability to Neurological Disorders
1:11:08
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1:11:08Chronic uncontrolled stress is a risk factor for many different diseases including mental and neurodegenerative disorders. The effects of such stress on the brain differ considerably between females and males. However, the vast majority of preclinical studies in animal models have included only males which in some cases has resulted in therapeutic …
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Gluten, Leaky Gut, and Autoimmune Disease with Dr. Tom O'Bryan
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1:22:07Could chronic inflammation, gluten, and poor gut health be silently sabotaging your brain? In today’s episode, I interview Dr. Tom O’Bryan, a renowned expert in autoimmune disease and gluten. We discuss the profound connection between chronic inflammation, gut health, and brain function. Dr. O'Bryan explains how low-grade chronic inflammation, ofte…
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Does Chronic Infection Like Lyme Disease Contribute to Alzheimer’s? With Robby Besner
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1:11:16Are you worried about Alzheimer’s affecting you or a loved one? Discover how detoxification and infrared therapy could be the game-changer for brain health and prevention. In this episode, I interview Robby Besner, CEO of Therasage, to explore how detoxification and natural healing methods can enhance brain health. He shares his personal journey, w…
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Women's Health and The Brain with Dr. Wendie Trubow
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1:10:04Could everyday toxins, hormonal changes, and gut issues be quietly harming your brain? Dr. Wendie Trubow joins me to explain how women can protect their cognitive health before it’s too late. Dr. Wendie is a gynecologist, functional medicine doctor, author, and podcast host, and she's here to discuss the critical connection between women’s health, …
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Can Gut Health Help Prevent Alzheimer’s? With Dr. Peter Kan
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47:13What if the key to reversing Alzheimer’s lies not just in the brain, but in the connection between your gut, immune system, and neurological health? In this episode, Dr. Peter Kan, a triple-board certified specialist in Integrative Medicine, Functional Medicine, and Chiropractic Neurology, joins me to discuss a crucial approach to treating brain he…
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Marian Joëls and Ron de Kloet: How the Brain Responds to Stress in Health and Mental Disorders
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1:14:54In stressful situations the brain communicates with the adrenal glands stimulating them to release adrenaline and cortisol. This stress responsive neuroendocrine system plays important adaptive roles by regulating energy metabolism, attention, and learning and memory. However, without a recovery period chronic uncontrolled stress such as psychosoci…
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The Power of Fasting with Dr. David Jockers
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48:18Did you know fasting could be the key to preventing Alzheimer's and boosting brain function? In this episode, I interview Dr. David Jockers, a world-renowned expert in natural medicine and brain health. We discuss the powerful benefits of fasting, ketosis, and mitochondrial health. Dr. Jockers explains how fasting triggers autophagy, enabling the b…
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How Spike Protein May Accelerate Alzheimer’s & Cognitive Decline | Dr. Mobeen Syed
1:27:36
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1:27:36Could spike protein be the hidden culprit behind brain fog, cognitive decline, and even Alzheimer's disease? Dr. Mobeen Syed (also called Dr. Mobeen or DrBeen) joins me to discuss the concerning persistence of the spike protein in the body and its potential to accelerate the progression of neurodegenerative conditions. In this thought-provoking con…
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Getting Started Preventing Alzheimer's with Dr. Josh Helman
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39:36Alzheimer’s doesn’t have to be a one-way road. Dr. Josh Helman, my partner at Brain Power Clinics and a Harvard-trained physician, reveals why conventional medicine often fails patients and what we’re doing differently. We talk about the hidden causes of memory loss that most neurologists overlook, including infections, toxins, heavy metals, mold, …
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Transforming Senior Living: Building Longevity Communities to Prevent Alzheimer’s With Ted Teele
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53:51Are you ready for a new perspective on aging and brain health? In this episode, I had the privilege of interviewing Ted Teele, the visionary behind longevity communities. We discuss the future of senior living, examining how his groundbreaking approach combines science, technology, and wellness to create environments that foster healthier, happier …
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Josh Helman: Multipronged Approaches for Preventing and Treating Alzheimer’s Dementia
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59:38Clearly demonstrated as being effective for cardiovascular disease, lifestyle medicine is becoming an important discipline for the prevention and treatment of age-related brain disorders including Alzheimer’s and Parkinson’s diseases. In this episode I talk with Dr. Josh Helman about his experience working with patients at lifestyle medicine center…
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#65 - Dr. Mark Mattson | Neuroscience, Intermittent Fasting, and Brain Health
1:06:48
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1:06:48Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they interview Dr. Mark Mattson, one of the world’s leading neuroscientists and a pioneer in the study of aging, brain health, and neurodegenerative diseases. Dr. Mattson is Chief of the Laboratory of Neurosciences at the National Institute on Aging and Professor of Neuroscience…
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Grace (Beth) Stutzmann: Pivotal Role for Calcium in Brain Aging and Alzheimer’s Disease
53:14
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53:14The calcium ion controls neuronal network activity, synapse function and synaptic plasticity, and is a fundamental mediator of learning and memory. With aging and much more so in Alzheimer’s disease the ability of neurons to properly regulate their intracellular calcium levels becomes compromised. Evidence from human and laboratory animal studies h…
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Boost Your Memory with Science – Dr. Daniel Schacter
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49:22Ever wonder why you forget things or how multitasking is affecting your memory? Dr. Daniel Schacter, a professor at Harvard University and a memory expert, uncovers the surprising science behind memory errors and shares actionable tips to enhance your brain health and reduce the risk of Alzheimer’s. Professor Schacter shares insights from his groun…
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Can Skipping Meals Prevent Alzheimer’s? Dr. Mark Mattson’s Groundbreaking Research
1:13:08
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1:13:08What if skipping a meal could help save your brain? In this episode, Dr. Mark Mattson and I discuss the fascinating world of intermittent fasting. We explore cutting-edge science and groundbreaking research that shows how intermittent fasting can not only prevent Alzheimer’s but may also reverse its effects. Dr. Mattson, a neuroscientist and a lead…
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This Neurotransmitter Could be Causing Alzheimer's with Dr. Mark Mattson
1:40:47
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1:40:47Could a single neurotransmitter be fueling the progression of Alzheimer's? Dr. Mark Mattson, a leading expert on Alzheimer's, joins me to explore the groundbreaking research that reveals how this often-overlooked molecule may be impacting your brain health and what you can do about it. Dr. Mattson shares his insights on how neurotransmitter imbalan…
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Can Water Fasting Reverse Cognitive Decline? Loren Lockman’s Surprising Insights
1:03:07
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1:03:07What if the key to improving brain health lies in something as simple and powerful as silence and fasting? In today’s episode, I’m joined by Loren Lockman, an expert in water fasting, who’s helped thousands reverse chronic conditions by allowing their bodies to heal naturally. Loren shares his journey of overcoming chronic illness with fasting, rev…
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Andrew Dillin – Stress and Aging: Mitochondria are Hubs of Information Flow in and Between Cells
49:00
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49:00Long believed to function only as the cell’s powerhouse research is revealing that mitochondria actively control a cell’s response to various types of stress. Even more amazingly mitochondria send stress-related signals between cells. In this episode UC Berkeley Professor Andy Dillin has made major advances in understanding basic mechanisms of agin…
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#105 Exogenous ketones, my coffee protocol, and supplements for blood sugar regulation (Premium Member Q&A July 2025)
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33:05Become a FoundMyFitness Premium Member to access the full episode In this special episode, you'll get an exclusive 30-minute preview of my latest Ask Me Anything (AMA) session, normally reserved for FoundMyFitness Premium Members. Each month, Premium Members join me live to receive direct answers to their most pressing questions on nutrition, suppl…
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The Medical Doctor Silenced for Reversing Alzheimer's with Dr. Robert Hedaya
1:29:55
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1:29:55What if everything you know about Alzheimer’s treatment is wrong? Dr. Robert Hedaya, a psychiatrist and physician who reversed Alzheimer’s, reveals how his revolutionary approach was silenced by the very institutions meant to protect patients. In this eye-opening episode, Dr. Hedaya joins me to discuss how his functional medicine approach to Alzhei…
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Fasting to Prevent Alzheimer’s? Dr. Valter Longo’s Shocking Findings
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51:07Can fasting and food timing hold the key to preventing Alzheimer's? In today's episode, I'm joined by Dr. Valter Longo, a pioneer in the field of fasting and longevity science and founder of The Create Cures Foundation. He is a biochemist and longevity researcher who leads groundbreaking work on aging, fasting-mimicking diets (FMD), and disease pre…
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Marc Freeman – How Astrocytes Control Neural Circuits in Brain Development, Plasticity, and Disease
1:18:41
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1:18:41While neurons and the circuits the form have been the major focus of brain research the human brain contains at least as many cells that are not neurons of which astrocytes are by far the most abundant. During the past decade there have been numerous studies that reveal novel and very active roles for astrocytes in regulating the growth of neurons,…
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In this episode of Scaling Clean, we’re joined by Brad Mattson — often called a ‘Silicon Valley Legend’ for taking two companies from garage startups to Nasdaq. He’s also been a VC and led two clean economy companies, bringing decades of wisdom to our conversation. About Tigercomm Tigercomm is top U.S. marketing communications and public affairs fi…
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Episode 2 of Scaling Clean features Robert E. Fishman, veteran CEO of three energy companies with experience in renewables, fossil fuels, and nuclear. Bob shares thoughtful insights on leadership and offers valuable lessons on assembling and maintaining strong executive teams. About Tigercomm: Tigercomm is top U.S. cleantech PR firm agency helping …
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Episode 3 of Scaling Clean features Mark Bassett, former CEO of Hemlock Semiconductor. With a Ph.D. in Chemical Engineering and a career spanning Dow Chemical and Hemlock, Mark shares insights on leading technical manufacturing companies, including driving sales growth during the COVID recession. About Tigercomm Tigercomm is top U.S. marketing comm…
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In this episode of Scaling Clean, we talk with Chad Farrell, CEO of Encore Renewable Energy. Unlike our previous guests, Chad is leading his first company — one he founded nearly 15 years ago. Encore develops community‑scale renewable energy projects, often on reclaimed industrial land, giving Chad unique lessons to share with first‑time cleantech …
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In this episode of Scaling Clean, we’re joined by Abby Hopper, President and CEO of the Solar Energy Industries Association (SEIA). A lawyer by training and veteran of major regulatory roles, Abby has led SEIA through pivotal years for the U.S. solar industry and brings unique insights on guiding teams through complex challenges. View transcript: h…
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Do you love eating out? Be cautious, as your favorite dish may be harmful to your brain. What food could this be? This is one of the questions that I answer in my second Ask Me Anything episode. Today, I’m addressing your pressing questions on a range of topics, from MCT oil to brain health and the risks associated with certain food types. First, w…
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Reverse Your Brain Age? The New Test That Could Prevent Alzheimer’s With Dr. Christin Glorioso
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56:01What if you could know the age of your brain today and take action to reverse it? In this episode, I interview Dr. Christin Glorioso, CEO and co-founder of NeuroAge Therapeutics, who reveals how we can now track and reverse brain aging, even before Alzheimer’s symptoms appear. You won't want to miss her insights into groundbreaking technologies, in…
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Polina Shichkova: Metabolic and Biophysical Modeling of Breakdown and Repair of the Aging Brain
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1:03:05Because neurons in the brain are electrically excitable and active 24/7 the brain consumes relatively large amounts of energy and must adapt to varying demands on its neural networks. The cellular and molecular complexity of the brain presents a major challenge for understanding not only its second-by-second function but also how neural networks ar…
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Preventing Chronic Disease with Food – Dr. Joel Fuhrman Explains
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52:37Did you know that a plant-rich, nutrient-dense diet can not only prevent chronic diseases like Alzheimer's but also enhance our mental clarity and overall well-being? In this episode, I speak with Dr. Joel Fuhrman, a leading physician in the field of nutritional medicine. Dr. Fuhrman reveals how diet plays a crucial role in preventing and even reve…
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How Insulin Resistance Impacts Alzheimer’s: Insights From Dr. Yousef Elyaman
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52:00What if the root cause of Alzheimer's isn't just in the brain? Discover how insulin resistance, toxins, and inflammation are silently linked to cognitive decline and how a holistic approach could offer hope for prevention and reversal. In this episode, I had the privilege of interviewing Dr. Yousef Elyaman, a double board-certified physician, about…
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Corinde Wiers: The Potential of Ketone-Based Interventions for the Treatment of Addiction
1:07:26
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1:07:26Research on substance use disorders has largely focused on understanding the key neural circuits and neurotransmitter systems that are altered, and on behavioral and pharmacological interventions. However, emerging research findings suggest that alcohol use disorder (AUD) is associated with alterations in energy metabolism and can accelerate brain …
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#64 - Dr. Yanina Pepino | The Neuroscience of Taste, Sweeteners, and Metabolic Health
1:28:24
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1:28:24Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they interview Dr. Yanina Pepino, a renowned professor of Ingestive Behavior at the University of Illinois. With a background in medicine and a research trajectory that spans Washington University’s Center for Human Nutrition to her current work in sensory biology, Dr. Pepino br…
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#104 Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, & Sleep
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3:01:02Get access to 130 episodes of my premium podcast, The Aliquot, as a FoundMyFitness Premium Member Insulin resistance silently shapes the trajectory of nearly every major chronic disease, yet it's often overlooked until blood sugar abnormalities become obvious. In this episode, Dr. Ben Bikman exposes the dietary culprits that drive metabolic dysfunc…
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You CAN Grow New Brain Cells With Dr. Brant Cortright
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1:12:10Did you know that you can grow new brain cells as an adult? In this episode, Dr. Brant Cortright, author of The Neurogenesis Diet and Lifestyle, joins me to share cutting-edge insights on how diet, lifestyle, and natural supplements can help stimulate the growth of new brain cells and enhance brain health. Dr. Cortright reveals that the brain is ca…
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The Surprising Link Between Emotional Overload and Cognitive Decline With Alex Howard
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38:00Did you know that trauma might be at the root of chronic conditions like Alzheimer’s? In today’s episode, I sit down with Alex Howard, founder of The Optimum Health Clinic, to explore how emotional overload and childhood trauma contribute to cognitive decline and other chronic health issues. We dive into Alex's healing journey and how his personal …
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Henning Fenselau – Neural Circuits Controlling Appetite and Energy Metabolism and GLP-1 Actions
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56:52Appetite (hunger and satiety) is controlled by neural circuits in the brain – particularly in the hypothalamus – and their reciprocal connections to peripheral organs involved in energy metabolism (gut and liver). Understanding the structural organization of these circuits (their synaptic connections) and their neurochemistry (particularly which ne…
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The Power of Sleep With Dr. Michael Breus
1:23:42
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1:23:42Are you struggling with sleep issues? You're not alone. In this episode, I sit down with Dr. Michael Breus, one of the world's leading sleep experts, to explore the profound impact sleep has on our brain health. From chronotypes to sleep hygiene, you'll learn actionable tips that can transform your sleep and improve your memory, especially if you'r…
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The Diet That Helped Reverse Schizophrenia: Daniel Helman on Mental Health Recovery
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1:13:38Living with a mental health challenge can make everyday tasks feel overwhelming, turning even the simplest things into struggles that others may not fully understand. Whether you're facing it yourself or supporting a loved one, the weight of these challenges can make life harder in ways that aren’t always visible. Sometimes you wonder if there's ho…
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#63 - Dr. Dominic D'Agostino | Advancing Metabolic Therapies Through Ketosis and Resilience Research
1:11:35
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1:11:35Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they speak with Dr. Dominic D’Agostino, Associate Professor at the University of South Florida and research scientist at the Institute for Human and Machine Cognition (IHMC). Renowned for his work on metabolic therapies, Dr. D’Agostino has led pioneering research into how nutrit…
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Tessa Montague: Disappearing Act - How the Brain Controls Camouflage in Cuttlefish and Octopuses
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1:09:01One of the most remarkable feats of biological ‘wizardry’ in the animal kingdom is the ability of some cephalopods (octopuses, squids, and cuttlefish) to rapidly change the color, patterning, and texture of their skin so as to blend in with their background. They accomplish these feats through the linking of neural circuits in the visual system and…
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Are you struggling with sleep, brain fog, or memory loss? Do you have some burning questions about your health? Today, I'm hosting a Q&A episode where I answer some frequently asked questions. From tackling poor sleep to managing ADHD symptoms, I offer science-backed solutions that are simple and effective, allowing you to implement them today. I c…
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