Blood Labs, Clear Answers The Anthony Amen Show podcast

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Most lab reports end with a shrug: “You’re fine.” At Redefine Fitness and on The Anthony Amen Show (formerly Health & Fitness Redefined), we believe you deserve better than “fine.” In this episode, Brent from Sage Healthspan joins us to break down how to read your blood work with confidence, track trends over time, and turn numbers into clear, doable action steps that actually move your health forward.

We unpack why “normal” lab ranges aren’t the gold standard—especially in a population where metabolic dysfunction is common. Brent explains how Sage uses a closed-data AI system to protect your privacy while translating raw biomarkers into insights you can understand. We explore the overlooked markers that genuinely change prevention plans:
• ApoB for cardiovascular risk (far more predictive than total cholesterol)
• Lp(a) for spotting hidden genetic risk
• PSA as an early, frictionless lifesaver for men
• Full female hormone panels that reveal what piecemeal testing often misses

We also dig into composite markers, key ratios, and biological age—not as verdicts, but as guideposts that help you choose your next right step.

Then we connect labs to real life. Sleep, training load, sunlight, season, fasting, stress, and even your environment all shape your numbers. Wearables like Oura help you decide when to push or pull back. Vitamin D fluctuates with the weather. Testosterone changes with fasting and sleep. Context matters as much as the score itself.

Brent walks through how Sage Healthspan centralizes historical labs, normalizes units, explains biomarkers in plain English, and even generates a smart question list you can email directly to your doctor so every appointment is productive. The goal is simple: reduce friction, increase clarity, and build health literacy that compounds over time.

If you’re ready to go from “okay” to optimal—and want a framework that aligns with the Redefine Fitness philosophy that fitness is medicine—this episode will show you how to take ownership of your data, fill the gaps in your panels affordably, and make better daily decisions backed by evidence.

Subscribe, share with a friend who’s ready to take control of their health, and leave a review to help more listeners discover the show and understand their biology with confidence.

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Learn More at: www.Redefine-Fitness.com

Chapters

1. Host’s Injury And Recovery Lessons (00:00:00)

2. Meet Brent And His Engineering Lens (00:01:30)

3. The Doctor Visit That Sparked Sage (00:03:00)

4. Building The Sage App And Privacy (00:06:30)

5. Closed-Data LLM And “Optimal” Ranges (00:09:20)

6. Biomarkers As A Symphony Over Time (00:13:00)

7. Testosterone, Context, And Trends (00:16:30)

8. Health Agency And Demystifying Labs (00:20:00)

9. Wearables, Urine, And Environment Data (00:23:30)

10. What Panels Miss: PSA, Lp(a), ApoB (00:27:00)

11. Women’s Hormones And Complete Panels (00:31:00)

12. Frequency, Seasonality, And Vitamin D (00:34:00)

13. Access And Cost: Filling Lab Gaps (00:37:00)

14. Beyond Total Cholesterol: Ratios And ApoB (00:40:00)

15. Biological Age As A Composite Tool (00:43:00)

16. At-Home Testing And Reducing Friction (00:46:00)

17. Culture, Education, And Compounding Habits (00:50:00)

309 episodes