Welcome to 'Mike's on Mike,' your newest favorite political podcast. Hosted by Mike Miller, Mike Tolbert, and Mike Hightower. We delve deep into the political landscape. Tune in every week as we unpack the complex world of politics, observing and discussing the most pressing issues of the time. Drawing from our extensive experience and unique perspectives, we're dedicated to providing you with thoughtful insights, sparking meaningful discussions, and challenging conventional wisdom. So, whet ...
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Note to File is a podcast for clinical research sites - interviews, best practices, and candid commentary from Brad Hightower, founder of Hightower Clinical and clinical research professional.
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New episode every Wednesday! Join the Barbell Shrugged crew in conversations about fitness, training, and frequent interviews w/ CrossFit Games athletes!
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Clinical Research Confessions: PE, Trials, and Research Sins
30:21
30:21
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30:21In this episode of Note to File, we dive deep into the world of clinical research, exploring the challenges of resident physician training, the impact of private equity on clinical trial management systems, and the often-unspoken ethical dilemmas in the field. Join us as we unpack difficult sponsor behaviors, share hilarious research confessions, a…
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The Truth About GLP-1 Medications w/ Dr. Garrett Butler, Anders Varner, Doug Larson, and Travis Mash #798
55:26
55:26
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55:26Garrett Butler, MD. Husband, father, son, friend, and family doc in rural WV. Undergraduate in Physics from Johns Hopkins University. Undergraduate in Molecular and Cell Biology from Towson University. MD from West Virginia University School of Medicine. Family Medicine residency at WVU SOM. Hospitalist at Vandalia Health Davis Medical Center. Outp…
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The evolution of the Florida Times Union between 2003 and 2025
39:31
39:31
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39:31This week's guest on Mikes on Mic is Mary Kelli Palka, former executive editor of the Times Union. Mary Kelli joined the TU in 2003 as a staff reporter, later as Investigative Editor and finally as Executive Editor. She talks about the challenges for a daily paper, the shrinking number of staff reporters, the changing ownership and the increasing r…
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Clinical Trials 2.0: AI, Predictions, and the Future of Research with Lokavant
48:59
48:59
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48:59Special Pope election edition. In this episode, Rohit Nambisan from Lokavant and Jonathan Crowther from Pfizer discuss their innovative approach to clinical trial forecasting. They explore how advanced data analytics and AI can help predict and improve trial operational success, from site selection to protocol design. The conversation delves into r…
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Physiology Friday: [NUTRITION 101] The Exact Calories, Macros, and Micronutrients to Fuel Performance and Optimize Health w/ Anders Varner, Doug Larson, Travis Mash and Dan Garner
46:51
46:51
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46:51In today’s episode of Barbell Shrugged you will learn: How to determine total calories for your goals Why maintenance calories are important for body composition and health Why calories determine the size of your body Understanding energy balance and finding your activity multiplier How to properly increase and decrease your caloric intake to reach…
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CROs are Broken: Fixing Clinical Trials from the Inside Out with Meri Beckwith - Lindus Health
50:03
50:03
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50:03In this episode, Meri Beckwith from Lindus Health discusses his journey from venture capital to clinical research, sharing insights on the inefficiencies of traditional CROs. He explains how Lindus is taking a different approach by aligning incentives, focusing on patient experience, and developing innovative trial models. The conversation explores…
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Flexible Cardio for People that Hate Cardio w/ Dr. Michael T. Nelson, Anders Varner, Doug Larson, and Travis Mash #797
49:04
49:04
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49:04Dr. Mike T. Nelson has spent 18 years of his life learning how the human body works, specifically focusing on how to properly condition it to burn fat and become stronger, more flexible, and healthier. He’s been called in to share his techniques with top government agencies, universities and colleges, fitness organizations and fanatics. The techniq…
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In this episode of Sticky Notes, Brad & Denali dive into the latest trends in clinical research, exploring how younger adults are getting medical advice from social media, the potential impact of pharmaceutical tariffs on R&D, and the evolving landscape of decentralized clinical trials. We discuss the challenges and opportunities of involving healt…
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Cracks in the GOP: State legislators and the Governor spar over tax cuts and tourism.
28:03
28:03
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28:03The usually united Governor and the Republican dominated legislature forces the 2025 session into overtime or special session to iron out tax differences, including the bed taxes which partially fund Visit Jacksonville and other cities tourist marketing organizations to a standstill. Visit Jacksonville's CEO Michael Corrigan joins the Mikes to disc…
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Barefoot Revolution w/ Mark Sisson, Anders Varner, Doug Larson, and Travis Mash #796
1:04:32
1:04:32
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1:04:32Mark Sisson, widely regarded as the forefather of the Primal/Paleo lifestyle movement, is an innovator and trendsetter in the health and fitness world. He has written several best-selling books and a number-one-ranked blog promoting ancestral living. Mark founded Primal Kitchen foods to introduce healthful options for condiments and sauces to the m…
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We sit down with Bree Burks from Veeva to discuss the company's latest innovations in clinical research technology. We dive deep into Veeva's upcoming CTMS (Clinical Trial Management System), their strategy for connecting sponsors and sites, and the importance of creating more streamlined, user-friendly technology for clinical research sites. Bree …
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UNF’s Michael Binder Unpacks the Political Drama Dividing Florida—from Jacksonville's City Hall to Tallahassee
23:47
23:47
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23:47UNF Professor Michael Binder returns to Mikes on Mic to share his thoughts on the current political climate in Tallahassee as the governor finds his influence on the legislature waning. Dr. Binder also gives his assessment of Democrat Mayor Deegan's first 22 months and her relationship with the super majority Republican City Council and her priorit…
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Muscle Analytics for Human Performance w/ Dr. Doug Goldstein, Anders Varner, Doug Larson, and Travis Mash #795
52:27
52:27
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52:27Founder, Altitude Performance & Measured Motion Former two‑sport collegiate athlete turned board‑certified orthopedic specialist, Dr. Goldstein blends lab‑grade muscle science with hands‑on care. After earning his DPT from the University of Colorado and completing both an orthopedic residency and fellowship, he launched Altitude Performance, a conc…
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In this episode, Brad and Denali dive into recent industry developments, including Bay Pine's $1.5 billion acquisition of CenExel clinical research site network, the FDA's potential shift to AI-based animal testing alternatives, growing challenges with clinical trial recruitment and public trust, emerging pharmaceutical import tariffs, and the ongo…
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Inside Jacksonville with Mayor Donna Deegan!
20:28
20:28
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20:28Join Mike Miller, Mike Tolbert, and Mike Hightower as they sit down for an in-depth conversation with Jacksonville Mayor Donna Deegan, broadcasting live from her office in City Hall. Mayor Deegan reflects on her first 22 months, since taking office in July 2023). They dive into crucial topics facing Jacksonville. Tune in to the show on your favorit…
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Physiology Friday: [Inflammation] The Surprising Link Between Nutrition, Muscle, and Inflammation w/ Anders Varner, Doug Larson, Coach Travis Mash and Dan Garner
51:56
51:56
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51:56In this Episode of Barbell Shrugged: What is inflammation why does your body have it How inflammation can improve performance The difference between Good and Bad inflammation Proper ways to reduce inflammation What is Chronic vs. Acute Inflammation Work with RAPID Health Optimization Connect with our guests: Anders Varner on Instagram Doug Larson o…
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Living Alcohol Free w/ James Swanwick, Anders Varner, Doug Larson, and Travis Mash #794
56:50
56:50
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56:50Swanwick has worked as a print, TV and radio journalist. He began his career in 1993 as a reporter at The Courier-Mail in Brisbane, Australia. In 1996, Swanwick won the Queensland Media Award for his interview and exposé on Pauline Hanson, one of Australia’s most publicized and controversial political figures. Swanwick moved to London in 1999 where…
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In this episode Jim Kremidas, Executive Director of the Association of Multi-Site Research Corporations (AMRC), discusses the evolving landscape of clinical research sites. We explore how multi-site research corporations are working to improve operational efficiency, quality standards, and patient experiences in clinical trials. Kremidas shares ins…
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From Polling to Frontlines: Bruce Barcelo’s Mission Shift in Ukraine’s Darkest Hour
21:51
21:51
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21:51Mikes on Mic welcomes political strategist-turned-humanitarian Bruce Barcelo for a gripping, behind-the-scenes look at how one nonprofit transformed overnight when war broke out in Ukraine. When Russia invaded Ukraine on February 24, 2022, Bruce—an American pollster with three decades of ties to the country—didn’t just watch the headlines. He answe…
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Physiology Friday: [Cholesterol] How to Read Bloodwork for Lipids, Triglycerides, and Fatty Acids w/ Anders Varner, Doug Larson, and Dan Garner Barbell Shrugged
44:22
44:22
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44:22In today’s episode of Barbell Shrugged you will learn: What are lipids What is cholesterol The difference between HDL and LDL cholesterol Why there is no such thing as “good” or “bad” cholesterol What are the bloodwork numbers for optimal cholesterol What is the perfect ratio of HDL and LDL Ratios for Triglycerides to HDL for optimal health Mechani…
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Building the Endurance Athlete w/ Javier Pineda, Anders Varner, Doug Larson, and Travis Mash #793
52:18
52:18
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52:18Javier Pineda, endurance coach at RAPID Health Optimization and founder of Endurance Cartel, empowers athletes and professionals to master strength and stamina. With ten Ironman triathlons and two Ironman 70.3 races under his belt, he’s a CHEK Practitioner with top-tier certifications and insights from various mentors across his career. At DBC Fitn…
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From The Archives: Jamie Massengill - SSM Health
1:02:43
1:02:43
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1:02:43In this episode, we sit down with Jamie Massengill from SSM Health to unpack the complex world of clinical research in community healthcare. We dive deep into the challenges of launching successful research programs, exploring innovative partnership models, physician engagement strategies, and how community hospitals can transform clinical trials. …
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Jacksonville political pollster's thoughts on his long relationship with Ukraine
25:25
25:25
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25:25Jacksonville's Bruce Barcelo has had a personal relationship consulting the government of Ukraine since before the Russian invasion three years ago. Bruce joins the Mikes this week and next with his observations about Ukraine's independence from the former Soviet Union and helping them in their democratization process and their elections. Tune in t…
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Physiology Friday: Managing Stress and Performance for Tactical Populations w/ Dr. Mike Lane, Anders Varner, Doug Larson, and Travis Mash
49:15
49:15
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49:15Mike Lane is a professor at eastern Kentucky university teaching in the parks, recreation, exercise, and sports science on the graduate and undergraduate level. His phd is in exercise physiology with an emphasis in muscle physiology. Currently he works with a variety of sports and tactical athletes and performs research tracking those athletes and …
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Heart Attack Awareness for Fit People w/ Joel Jamieson, Anders Varner, Doug Larson, and Travis Mash #792
46:43
46:43
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46:43Joel Jamieson is widely considered one of the world’s foremost authorities on strength and conditioning for combat sports, having trained many of the sports best athletes since 2004. He is the author of the bestselling book Ultimate MMA Conditioning and is a contributing writer to several top magazines and a frequent guest speaker at conferences an…
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Was the murder trial of Kenneth Hartley a case of an innocent man wrongfully sentenced or perhaps railroaded prosecution?
29:58
29:58
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29:58In 1991, Gino Mayhew, age 17, was kidnapped and murdered.Kenneth Hartley was convicted of kidnapping and murder and sentenced to die in the electric chair. But there were many questions about the case, particularly the testimony against Hartley coming from jailhouse informants. Our guest this week is Tributary reporter Nichole Manna who investigate…
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In this episode we talk with Chris Venezia, CEO of ProofPilot, about the often-overlooked operational challenges in clinical trials. Chris shares his unexpected journey into clinical research and reveals how ProofPilot is transforming the industry by simplifying communication, document sharing, and patient engagement. From addressing fundamental co…
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Physiology Friday: [Recovery] How to Build a Resilient Physiology w/ Anders Varner Doug Larson, and Dan Garner Barbell Shrugged
48:51
48:51
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48:51In today’s episode of Barbell Shrugged you will learn: How to define resilience Understanding psychology vs physiological resilience What are the biomarkers of resilience Cortisol wakening response and how it relates to stress response Is balance possible between stress and recovery How much stress can you body handle before physiology begins to br…
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Rowing for Fitness, Strength, and Sport w/ Shane Farmer, Anders Varner, Doug Larson, and Travis Mash #791
57:29
57:29
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57:29Shane Farmer is the founder of Dark Horse Rowing. He’s a rower, a 4X CrossFit Games athlete, former gym owner, Concept2 Master Instructor and has made his career de-mystifying rowing for non-rowers. He’s married with two kids and has 13 chickens and an orchard. He loves soil regeneration, permaculture, and testing himself regularly at new and inter…
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We talk to Science 37 CEO Tyler Van Horn and discuss the past, present and future of the company - everything you wanted to know about Science 37 but were afraid to ask.
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Two very important issues we may be facing in the coming months; Eliminating property taxes as a source of local revenue, and Duval DOGE. Councilman Matt Carlucci again joins the Mikes to give us his take on both of these potential game changers. Join us on this week’s episode of Mikes on Mic. Tune in to the show on your favorite Podcasting platfor…
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This episode is dedicated to feedback about the recent Save Our Sites (SOS) conference in Oklahoma City. The founders, Judy Galindo, Ashley Margot, Chris Sauber, Monica Cultiva and Dan Sfera join as we take live feedback from the livestream audience.
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Physiology Friday: [Body Transformation] Simple Strategies to Getting Shredded w/ Anders Varner, Doug Larson, and Dan Garner
48:10
48:10
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48:10In today’s episode of Barbell Shrugged you will learn: Setting goals for physique transformation How long should you plan for a bulk and cut Strategies for building muscle on a bulk How to handle lagging body parts Time frame for cutting weight and getting shredded Being realistic on the amount of fat you truly need to lose Prep cycles for peak wee…
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Pain Free Performance at All Ages w/ Dr. Melissa Capurro, Anders Varner, Doug Larson, and Travis Mash #790
54:47
54:47
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54:47Melissa is a performance physical therapist and is heavily involved in the CrossFit space as a healthcare provider, as well as an athlete. Melissa grew up in the Metropolitan New York area, but now resides in the Tampa Bay area. Upon graduating from PT school, Melissa started working in an outpatient orthopedic physical therapy practice, but was un…
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A short recap of recent news, events, social media posts, gossip, announcements, and anything else in the clinical research space. In this episode Paul Ivsin joins to talk Science 37 v Science 38, PEs buyout of Walgreens and CRA/CRC relationships.
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What’s the latest on downtown development? Mikes on Mic this week again features Downtown Investment Authority CEO, Lori Boyer. We’re seeing more cranes popping up downtown meaning more projects are breaking ground. Where are we in residential and commercial development? We discuss that and other issues with DIA CEO Lori Boyer this week on Mikes On…
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Physiology Friday: How to Build a Killer Cardiovascular System w/ Dr. Mike T. Nelson, Anders Varner, Doug Larson, and Travis Mash
51:58
51:58
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51:58In today’s episode of Barbell Shrugged, Anders Varner, Doug Larson, and Travis sit down with Anders coach, Dr. Mike T. Nelson. For those that have followed the show, you know Anders has been in pursuit of running a sub-6 minute mile at the age of 40. Dr. Nelson is the coach Anders hired to help with that goal. In this episode the crew walks through…
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Building the Best Pilots in the World w/ Zachary Carson, Anders Varner, Doug Larson, and Travis Mash #789
54:51
54:51
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54:51Zachary Carson is a highly experienced Aerospace Physiology Officer with a deep understanding of human factors and risk mitigation in high-stakes operational environments. His expertise lies in optimizing human performance within complex aerospace systems. As a subject matter expert, Carson specializes in identifying and addressing the unique chall…
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Today we discuss vendor relationships , representation & its impact on business, diagnosis & after care - the main unmet need within pharma - and embroidery throwing.
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Mikes On Mic is holding a round table discussion of some of the most current issues facing NE Florida and the state. They discuss the current rift between Mayor Deegan and former City Council president Ron Salem over how to negotiate the deal for the UF Grad School. The Mikes also discuss the $3 billion deficit in the Police Pension Fund and rampin…
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Physiology Friday: [Optimal vs. Normal Health] Why Normal Reference Ranges Will Not Lead You to Optimal Health w/ Anders Varner, Doug Larson, Travis Mash and Dan Garner
55:45
55:45
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55:45In this Episode: The spectrum of health from sick, to not sick, and to optimal. Optimal is a word thrown around with ease in the healthy space. What does optimal health look and feel like? Why are the current blood markers in a normal range and not optimal? Where are normal reference ranges created? If you want to know optimal ranges, where do you …
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Building a Fitness Franchise w/ Brandon Cullen, Anders Varner, Doug Larson, and Travis Mash #788
55:07
55:07
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55:07Born into an entrepreneurial family in Ontario, Canada, Brandon Cullen was raised with a front-row seat to hard work and high expectations. Pushed by his father to excel both in life and on the ice, Brandon’s grit landed him a spot in the New York Rangers’ minor league system. But when a career-ending concussion shattered his hockey dreams, everyth…
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In this episode Dan Sfera joins us to cover the somewhat puzzling creation of the Association for Multisite Corporations (AMRC), a big time data breach from DM Clinical Research, and why everything in clinical research is an emergency.
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The evolution of the Jacksonville Civic Council with CEO Dennis Whittle
25:57
25:57
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25:57In 1993, the so-called Non-Group was formed at the time to tackle education issues in Jacksonville. In 2009, the organization of civic minded business leaders disbanded the Non Group and created the Jacksonville Civic Council. While the group was still focusing on important issues facing the city, it broadened the issues they addressed including th…
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Physiology Friday: [Psoriasis] A 3-Step System to Find Root Cause, Relief, and Symptom Management w/ Anders Varner, Doug Larson, Travis Mash, and Dan Garner
40:03
40:03
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40:03What is psoriasis. How is it related to other skin issues like eczema, acne, and Rosacea. What is causing the body to overproduce skin cells as a protective measure. What lab tests likely need to be ordered to see immune disfunction and root causes. Topical treatments that help manage symptoms vs. addressing root cause. Are the skin issues the firs…
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Building a Homestead Nursing Home and Finding the Right Primary Care Physician w/ Dr. Garrett Butler, Anders Varner, Doug Larson, and Travis Mash #787
57:47
57:47
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57:47Garrett Butler, MD, is a devoted family man and physician serving rural West Virginia as a husband, father, son, and friend. With a strong academic foundation, he earned undergraduate degrees in Physics from Johns Hopkins University and Molecular and Cell Biology from Towson University, followed by an MD and Family Medicine residency from West Virg…
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Jacksonville’s mayor and the City Council have recently faced some difficult and at times controversial decisions about current and future issues which share one thing in common; they all cost money? What projects and programs should the city help finance and where will the money come from? Who better to ask than a former mayor who faced and dealt …
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Physiology Friday: [Brain Health] Science and Strategies for Optimizing Brain Health w/ Dan Garner, Anders Varner, Doug Larson, and Coach Travis Mash
49:24
49:24
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49:24In today’s episode of Barbell Shrugged, we'll be discussing the various factors that impact brain health and exploring strategies for optimizing brain function. First, we'll be discussing the impact of exercise on brain health. Research has shown that regular exercise can help to improve brain function, enhance cognitive performance, and even reduc…
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[Caloric Ranges] How to Eat More Food Without Gaining Weight w/ Zach Moore, Anders Varner, Doug Larson, and Travis Mash #786
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49:28
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49:28Zach Moore is a highly sought after nutrition and exercise coach who has personally coached over 1000 clients. His clientele have ranged from top level professional athletes and physique competitors to health enthusiasts of all ages. Moore has worked with some of the most well known companies in the industry including Precision Nutrition, Nourish B…
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Tariffs and a change in ownership of the Panama Canal impact Jaxport?
26:27
26:27
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26:27JaxPort is a major economic engine for NE Florida. How might tariffs and a change in ownership of the Panama Canal impact JaxPort? Our guest this week on Mikes on Mic is Robert Peek, JaxPort’s Chief Commercial Officer. We discuss how those two major international policies might impact business at the port. Join us this week for an in depth discussi…
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