The Alcohol Reset is a science-backed podcast designed to help you reset your habits, health, and relationship with alcohol. Hosted by best-selling author Mike Hardenbrook, each bite-sized episode explores neuroscience, nutrition, and habit formation, delivering practical strategies to help you drink less, sleep better, reduce cravings, and optimize your well-being—without judgment or extremes. It’s time for a reset.
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Inspiring sobriety stories and real talk about all things substance use. Stay up to date on upcoming streams, get on our email list, shop our store, and more at www.hardknoxtalks.com
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The Alcohol Problem Podcast aims to explore the nature of problem drinking with Dr James Morris and a range of guests. One to one support for your drinking is available with Dr James Morris at www.drjamesmorris.com
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This series interviews experts in the addictions field, with a focus on evidence-based, cutting-edge approaches to substance abuse problems such as: Cognitive Behavioral Therapy (CBT), pharmacotherapy, harm reduction, and many, many more. Your host Kenneth Anderson is the founder and CEO of The HAMS Harm Reduction Network and the author of "How to Change Your Drinking: a Harm Reduction Guide to Alcohol."
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Life after addiction isn't just possible - it's the norm. Studies show 3 out of 4 people who experience addiction eventually recover. The Recovery Stories Have Power podcast aims to center that hopeful message through authentic conversations that bring together people from all pathways of recovery and recovery allies.Through these conversations, we’ll build awareness, challenge societal stigma, and celebrate the role that recovery plays in improving the lives of individuals, families, and co ...
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This podcast will address the public health strategy of Harm Reduction, which is designed to reduce the adverse consequences of drug and alcohol use. The Dispensary will address cutting-edge approaches to substance abuse problems, information on Syringe Exchange Programs (SSPs), HIV/HCV education, and harm reduction methods to prevent overdoses and save lives. Harm Reduction experts and peer guests will educate the public about drugs while dispelling popular myths, misinformation, and stigma.
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Weekly Editors' Audio Summary for JAMA, the Journal of the American Medical Association
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The No More Dead Friends Podcast is a platform for anyone who has overcome alcohol or drug addiction to share their experience, strength and hope with others. This podcast is not affiliated with any 12-step fellowships. If you are interested in meetings please seek out a local 12-step meeting in your area. If you or a loved one think that you might need treatment please call 858-790-1937 to see what treatment options are available to you. If you are having a medical emergency please dial 911 ...
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When I found out my son was deep in the throes of Substance Use Disorder (SUD), chaos became the norm. As each step became more challenging, the information on SUDs, treatment, healing, and basically everything that comes with an SUD Family crisis, became overwhelming. Inundated with so much information, I felt like I had crossed space and time and landed in a new world. I actually had: I had entered the world of Recovery. My goal through this Podcast is to condense what I learned into small ...
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Welcome to Science News Daily, brought to you by Brief! Our AI selects the latest stories and top headlines and then delivers them to you each day in less than ten minutes (for more details, visit www.brief.news/how-it-works). Tune in to get your daily news on fascinating topics, including physics, biology, chemistry, astronomy, and more. Whether you're a science enthusiast, researcher, or simply curious about the wonders of the natural world, this podcast is your ultimate source for all thi ...
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Stacey Moore shares her journey through addiction, domestic violence, and suicide attempts while parenting kids with complex needs.
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53:01Send us a text Stacey Moore is a nurse, addict in recovery, suicide attempt survivor, and mother of children with complex needs. She speaks openly about surviving domestic violence, managing substance use while parenting, navigating mental health crises, and working in healthcare while in recovery. Her lived experience now guides her work at Saskat…
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Influenza and COVID-19 Multicomponent Vaccine, Procedural-Based Treatments for Mixed Urinary Incontinence, Estimating Reform Impact on the Medicare Advantage Quality Bonus Program, and more
6:32
6:32
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6:32Editor’s Summary by Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, and Anne R. Cappola, MD, ScM, Senior Editor at JAMA, for articles published from May 3-9, 2025.
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Hitting the gym and hitting the bar? You’re not alone. But what if that post-workout drink is slowing down your muscle recovery? In this episode, Mike Hardenbrook breaks down what really happens when alcohol and exercise collide: How alcohol slows muscle building and increases soreness Why it messes with your hormones, hydration, and deep sleep The…
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MiCO Reveals Marine Migration Patterns, HIV Drugs Show Alzheimer's Promise, AI Designs Synthetic DNA Breakthrough, Study Shows Learning Rewires Brain, and more...
11:31
11:31
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11:31(0:10): New Interactive Map MiCO Reveals Crucial Marine Migration Patterns for Global Conservation (2:32): HIV Drugs Show Promise in Reducing Alzheimer's Risk, UVA Study Reveals (4:38): Groundbreaking AI Designs Synthetic DNA to Control Gene Expression, Revolutionizing Gene Therapy (6:57): Learning Physically Rewires Brain, Enhancing Neural Communi…
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Feeling bloated, foggy, or just off after a couple drinks? Your liver might be waving a white flag. In this episode, Mike Hardenbrook breaks down what your liver really does, how alcohol can quietly wear it down, and the sneaky signs that your body’s detox center is running on fumes. You’ll learn: How alcohol overloads your liver and slows down met…
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LICONN Microscopy Revolutionizes Brain Imaging, Foresight AI Transforms NHS Healthcare, Study Uncovers Unexplored Seafloor, Study Debunks New Brunswick Brain Disease, and more...
12:02
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12:02(0:10): Revolutionary LICONN Microscopy Breaks Barriers in Brain Tissue Imaging, Boosting Connectomics Research (2:18): AI Model 'Foresight' Revolutionizes NHS with Predictive Healthcare, Tackles Inequality Amid Privacy Concerns (4:44): Study Reveals 99.999% of Deep Seafloor Unexplored, Urges Global Effort Against Mining Risks (7:13): Study Debunks…
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Feeling tired, puffy, or just not quite yourself lately? Alcohol might be adding fuel to the fire—literally. In this episode, Mike Hardenbrook breaks down how alcohol can keep inflammation levels high behind the scenes, even if you’re drinking moderately. You’ll learn: What inflammation really is (and why you might have it without realizing) How al…
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AI Boosts Breast Cancer Detection, AI Reveals Ancient Greek Scroll, SK Life Science Launches PVTX-405, Peptide Treatment Revolutionizes Trauma Care, and more...
11:08
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11:08(0:10): AI Enhances Breast Cancer Detection: Study Shows 76% Improvement in Identifying Missed Cases (1:57): AI Unveils Ancient Greek Scroll: Philodemus' 'On Vices' Identified in Herculaneum Discovery (3:55): SK Life Science Labs Unveils PVTX-405: A Game-Changing Immunotherapy for Cancer Treatment (6:11): Breakthrough Peptide Treatment Boosts Survi…
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Struggling with stubborn belly fat after 30—despite eating well and staying active? Alcohol might be playing a bigger role than you think. In this episode, Mike Hardenbrook breaks down the science behind alcohol and midsection weight gain, including: Why alcohol slows fat burning and stores more in your belly How hormonal changes after 30 make bell…
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MIT Unveils New TB Diagnostic, New Protein Boosts Metabolism, Generative AI Transforms Mitochondrial Research, Scribe Therapeutics Unveils CRISPR Data, and more...
11:01
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11:01(0:10): MIT Unveils Breakthrough TB Diagnostic Method Targeting ManLAM Glycan (2:21): New Protein Discovery Boosts Metabolism, Offers Hope for Obesity Treatment (4:02): Generative AI Revolutionizes Mitochondrial Research, Offering Breakthroughs in Disease Therapy and Synthetic Biology (6:35): Scribe Therapeutics Unveils Pioneering CRISPR Data for D…
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Trying to cut back on drinking without giving up your social life? Zebra Striping might be the game-changer you’ve been looking for. In this episode, Mike Hardenbrook breaks down this flexible new strategy for drinking less—without feeling like you’re missing out. You’ll learn: What Zebra Striping is and why it works How it helps reduce hangovers, …
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Study Links Phthalates to Heart Disease, Dogs Communicate with Sound Buttons, Alcohol Intake Accelerates Alzheimer's, Yeast on Skin Fights Superbugs, and more...
11:56
11:56
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11:56(0:10): Study Links Phthalate Exposure to Over 356,000 Global Heart Disease Deaths, Urges Urgent Regulations (2:54): Study Reveals Dogs May Communicate Complex Ideas Using Sound Buttons (5:03): Study Reveals Moderate Alcohol Intake Accelerates Alzheimer's Disease Progression (7:30): Yeast on Skin Fights Superbugs: New Research Unveils Potential Bre…
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No episode this week, we will be back next week though 🙏
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0:32Send us a text Hey everyone, just a quick note to let you know that there won’t be a new episode of Hard Knox Talks this week. Life has thrown a few unexpected things our way, and we’re taking a little time to pause and regroup. Thank you for your understanding and continued support — it means the world to us. We’ll be back next week with more real…
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Spending Reductions With the Medicare Shared Savings Program, Extended Caffeine Use in Preterm Infants, Survival Trends for Periviable Infants, and more
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7:43Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from April 26-May 2, 2025.
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Study Reveals Long COVID Biomarkers, DNA Links Picuris Pueblo to Chaco Canyon, Wearable Tech Detects Heart Attacks, JWST Redefines Cosmic Evolution, and more...
11:12
11:12
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11:12(0:10): Study Identifies Blood Proteins as Key Biomarkers for Long COVID Diagnosis and Treatment (1:56): DNA Study Confirms Picuris Pueblo's Ancestral Ties to Ancient Chaco Canyon Residents (4:15): Revolutionary Wearable Tech Detects Heart Attacks Faster Than Ever with 92.4% Accuracy (6:11): JWST Captures Distant Galaxies, Redefines Our Understandi…
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You don’t have to give up drinking completely to feel better, sometimes, just drinking less makes all the difference. In this episode, Mike Hardenbrook breaks down how to cut back without cutting it all out. Whether you’re aiming for better sleep, fewer regrets, or more energy in the morning, you’ll learn how to shift your habits in a way that actu…
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Ever tell yourself you’ll have “just one drink”… and then find yourself reaching for another? In this episode, Mike Hardenbrook explores the brain science behind that all-too-familiar moment—breaking down how alcohol affects your decision-making, reward system, and self-control in real time. You’ll learn: Why the first drink triggers powerful rewar…
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Isaacman Nominated as NASA Chief, Picuris Pueblo Confirms Chaco Ancestry, Magnetars Revealed as Gold Source, Study Reveals Astrocytes in Addiction, and more...
11:14
11:14
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11:14(0:10): Billionaire Jared Isaacman Nominated as NASA Chief, Advocates for Moon and Mars Missions Amid Budget Cuts (2:25): Picuris Pueblo Leads Groundbreaking DNA Study to Confirm Ancestral Links to Chaco Canyon (4:34): Breakthrough Study Reveals Magnetars as Key Source of Gold and Heavy Elements in Universe (6:39): New Study Reveals Astrocytes' Rol…
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Intermittent Sobriety: Does It Actually Work?
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10:10
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10:10Intermittent sobriety is gaining traction, and for good reason. Taking short, intentional breaks from alcohol can lead to better sleep, sharper focus, and a noticeable boost in energy and mood. In this episode, Mike Hardenbrook explores how drinking less—even just a few days a week—can help your body recover, your brain reset, and your habits shift…
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Study Links Plastics to Heart Disease, NASA Astronaut Feels Rejuvenated, MaaT034 Achieves Tumor Reduction, Noninvasive Brain-Spine Interface Promises Hope, and more...
11:34
11:34
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11:34(0:10): Study Links Phthalates in Plastics to 356,000 Global Heart Disease Deaths in 2018 (2:08): NASA's Oldest Astronaut Don Pettit Feels Decades Younger After Seven-Month ISS Mission (4:18): MaaT034 Shows Promising 83.7% Tumor Reduction in Mice at AACR 2025, Boosts Immunotherapy Outcomes (6:33): Breakthrough Noninvasive Brain-Spine Interface Prom…
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Ever wonder why “just a couple drinks” can leave you feeling tired, anxious, or totally off the next day? It’s not always about how much you drink — it’s about how fast, how often, and how your body has to recover. In this episode, Mike Hardenbrook breaks down the 1/2/3 Rule — a simple, science-backed approach to drinking more mindfully: Why one dr…
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Discovery of Massive Molecular Cloud, AI-Driven Test Transforms Prostate Cancer Detection, Perseverance Discovers Mars Secrets, Korean Scientists Develop Arthritis Test, and more...
11:27
11:27
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11:27(0:10): Discovery of Eos: Unveiling a Massive Molecular Cloud Near Earth, Revolutionizing Star Formation Studies (2:23): New Urine Test Revolutionizes Prostate Cancer Detection with AI-Driven Biomarkers (4:19): Perseverance Rover Uncovers Mars' Geological Secrets at Witch Hazel Hill (6:19): Revolutionary 10-Minute Test for Arthritis Diagnosis Devel…
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Austria Fights Honey Fraud with DNA Tests, ImmVira Shows Promise Against Brain Cancer, Nanotechnology Targets Breast Cancer, New Blood Test Predicts Heart Disease, and more...
11:43
11:43
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11:43(0:10): Austria Launches DNA Tests to Combat Honey Fraud Amid Rising EU Adulteration Concerns (2:18): ImmVira's Oncolytic Virus Shows Promise Against Aggressive Brain Cancer in Early Trials (4:21): Revolutionary Nanotechnology Targets Triple-Negative Breast Cancer with Precision, Reducing Side Effects (6:30): New Blood Test Outperforms Cholesterol …
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Why does alcohol make you pee so much? It’s more than just a party joke — there’s real science behind it. Alcohol messes with your body’s ability to hold onto water, drains essential minerals, and can leave you feeling dehydrated, foggy, or restless the next day. In this episode, Mike Hardenbrook breaks down what’s actually happening when you drink…
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Daniel and Donna share their opinions around harm reduction strategies and the further criminalization of substance use in Saskatchewan
30:27
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30:27Send us a text In this episode, Dan Hearn and Donna Gilchrist sit down to deliver a raw, no-holds-barred rant about the systemic failures and hypocrisies surrounding addiction treatment, harm reduction, and the criminalization of substance use. With decades of combined lived and professional experience, they dive into the complexities of trauma, ab…
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Shingles Vaccination and Dementia, Varenicline for Vaping Cessation, Mental Health Trends in Publicly Insured Children, and more
10:13
10:13
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10:13Editor’s Summary by Preeti Malani, MD, MS, and Chris Muth, MD, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from April 19-25, 2025.
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Think you're fine after a drink? Think again. Most people don’t realize alcohol takes about 20 minutes to fully kick in—and that delay could be the reason you end up drinking more than you planned. In this episode, Mike Hardenbrook breaks down the science behind the 20-minute rule and why it matters for anyone who drinks: How alcohol is absorbed—an…
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Breakthrough in Peanut Allergy Treatment, Oldest Hell Ant Fossil Discovered, Yeast Reveals Human Migration Patterns, Study Shows Iceberg Type Shift, and more...
12:02
12:02
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12:02(0:10): Breakthrough Peanut Allergy Study Shows Promising Desensitization for Adults (2:30): Oldest 'Hell Ant' Fossil Unearthed in Brazil: A 113-Million-Year-Old Evolutionary Marvel (4:37): Baker's Yeast Unveils Human Migration Patterns: A Historical Microbial Journey (6:46): Study Reveals Surprising Shift in Iceberg Types, Raises Sea Level Rise Co…
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Still craving that drink—even when you’re trying to cut back? It might not be about willpower at all. New science shows that nutrient deficiencies could be fueling your alcohol cravings from the inside out. In this episode, Mike Hardenbrook breaks down what your body might be missing: The top nutrient deficiencies linked to alcohol cravings How B1,…
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Study Reveals Corn Genetics Breakthrough, Catalyst Design Boosts Hydrogen Production, Piperacillin Revolutionizes Lyme Treatment, Study Reveals Tumor Spread Pathway, and more...
10:49
10:49
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10:49(0:10): Breakthrough Study Reveals Corn Genetics Key to Boosting Crop Resilience and Productivity (1:58): Breakthrough Catalyst Design Enhances Cost-Effective Hydrogen Production via Water Electrolysis (4:10): Breakthrough Lyme Disease Treatment: Piperacillin Offers Effective, Gut-Friendly Alternative to Doxycycline (6:08): Breakthrough Study Unvei…
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Teen Brain Health Boosted by Sleep, MIT Discovers Doomed Exoplanet Tail, Fossil-Free Iron Production Launched, Walking 9000 Steps Cuts Cancer Risk, and more...
10:32
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10:32(0:10): Study Reveals Teens' Brain Health Boosted by Just 15 Extra Minutes of Sleep (2:02): Doomed Exoplanet with Remarkable 9-Million-Kilometer Tail Discovered by MIT Researchers (4:35): Revolutionary Fossil-Free Iron Production Unveiled: A Game-Changer for Carbon-Heavy Steel Industry (6:38): Walking 9,000 Steps Daily Cuts Cancer Risk by 26%, New …
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Is your drink putting your brain at risk? New research reveals that heavy drinking can significantly increase your chances of developing brain damage associated with dementia. In this episode, Mike Hardenbrook breaks down what this means for your cognitive health: The connection between heavy alcohol consumption and brain lesions How drinking impac…
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Is that drink really helping your mood? While alcohol may seem like a quick way to unwind, it can have lasting effects on your mental health. In this episode, Mike Hardenbrook breaks down what this means for your well-being: How alcohol acts as a depressant and impacts mood The connection between drinking and anxiety or depression The role of L-The…
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Study Links Autism to Muscular Disorder, Stanford's RARE-seq Revolutionizes Cancer Detection, Carbene Breakthrough in Water, IISc Unveils Battery Tech Advancements, and more...
11:35
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11:35(0:10): Study Links Autism and Muscular Disorder: New Genetic Insight Offers Hope for Targeted Therapies (2:44): Stanford's RARE-seq Test Revolutionizes Cancer Detection with Enhanced RNA Sensitivity (4:44): Breakthrough: Stable Carbene Observed in Water for the First Time, Paving Way for Greener Chemistry (6:41): IISc Unveils Revolutionary Battery…
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Blood Pressure Control Reduces Dementia Risk, AI Model Diagnoses ADHD Accurately, Discovery Links Autism and Dystrophy, Microplastics Threaten Women's Fertility, and more...
12:31
12:31
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12:31(0:10): Intensive Blood Pressure Control May Cut Dementia Risk by 15%, Study Finds (2:37): AI Model Achieves 96.9% Accuracy in ADHD Diagnosis via Retinal Imaging (4:57): New Genetic Link Found Between Autism and Myotonic Dystrophy, Paving Way for Precision Therapies (7:21): Microplastics Found in Ovarian Fluid: New Threat to Women's Fertility and H…
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Wondering how your drinking habits affect your aging? The truth might surprise you. While a drink or two can be a social delight, alcohol has significant impacts on your skin, brain, and overall health as you age. In this episode, Mike Hardenbrook explores the connection between alcohol consumption and the aging process, including: How alcohol acce…
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From Trauma and Addiction to Healing and Advocacy: Chris Cavallo’s Journey Through Sexual Violence, Addiction, and Redemption
41:17
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41:17Send us a text In this episode of Hard Knox Talks, host Daniel Hearn sits down with Chris Cavallo—father, husband, and recovery advocate—who has transformed a life once ruled by addiction and trauma from sexual abuse, into one of hope, healing, and service. Chris shares his gripping story of resilience, from early struggles with sexual abuse and ye…
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Sex-Based Differences in Alcohol Consumption, ICU Patient Outcomes, Trends After Drug Decriminalization in British Columbia, and more
8:59
8:59
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8:59Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from April 12-18, 2025.
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Potential Biosignature on K2-18b Sparks Debate, Metformin Shows Promise Against AML, Breakthrough Reveals Brain Learning Secrets, Revolutionary Paste-Like Battery Emerges, and more...
11:47
11:47
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11:47(0:10): Potential Biosignature on Distant Planet K2-18b Sparks Debate Among Scientists (2:31): Affordable Diabetes Drug Metformin Shows Promise in Preventing Deadly Blood Cancer AML (5:01): Breakthrough Study Unveils Diverse Synaptic Plasticity, Revolutionizing Understanding of Brain Learning and Disorders (7:07): Revolutionary Paste-Like Battery P…
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Ever wondered why drinking can lead to unexpected weight gain? It’s not just about the calories—alcohol affects metabolism, appetite, and fat storage in ways you might not realize. In this episode, Mike Hardenbrook breaks down the science behind alcohol and weight gain, including: How alcohol slows down fat burning and disrupts metabolism Why drink…
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'Change resistant drinkers'? The blue light approach with Mark Holmes & Mike Ward
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46:57
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46:57In this episode we talk to Mark Holmes and Mike Ward about the Blue Light approach, which aims to challenge the belief that nothing can be done with drinkers who may be deemed as 'not wanting to change'. The Blue Light approach aims to show there are a range of positive strategies that can be used to manage risk, reduce harm and promote change. We …
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The Hidden Connection Between Alcohol and Gut
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7:49
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7:49Does alcohol really mess with your gut health? Absolutely. Drinking can cause gut issues, including imbalances in bacteria, inflammation, and a weakened gut lining. Research shows that alcohol disrupts digestion and can trigger bloating, fatigue, and cravings for unhealthy foods. In this episode, Mike Hardenbrook dives into what this means for your…
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Juvenile Colossal Squid Captured Live, James Webb Hints at Life, EMA Approves Leqembi for Alzheimer's, Study Traces Earth's Water Origins, and more...
11:43
11:43
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11:43(0:10): Historic First Footage of Juvenile Colossal Squid Stuns Global Viewers in Live Deep-Sea Dive (2:23): James Webb Telescope Hints at Life on Distant Exoplanet K2-18 b, But Questions Remain (4:55): EMA Approves Leqembi for Early Alzheimer's, Despite Efficacy and Safety Concerns (7:05): Oxford Study Suggests Earth's Water Originated from Enstat…
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Does milk thistle really help your liver handle alcohol? Science says it might. Your liver works hard to process alcohol, but excess drinking can cause inflammation and damage. Milk thistle, a centuries-old remedy, may help protect liver cells, reduce inflammation, and support regeneration. In this episode, Mike Hardenbrook breaks down what this me…
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17 States to See Auroras, Autism Diagnoses Reach New High, Groundbreaking Trial for Pig Organs, Study Links Sports Bras to Spine Harm, and more...
9:29
9:29
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9:29(0:10): Northern Lights Alert: 17 U.S. States to Witness Auroras Amid Solar Storm Surge (2:13): U.S. Autism Diagnoses Rise to 1 in 31 Kids: Better Screening, Not Vaccines, Drive Increase (4:19): Groundbreaking Trial to Test Gene-Edited Pig Organs for Human Transplants, Offering New Hope for Liver Failure (5:49): Study Reveals High-Support Sports Br…
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Study Warns of CT Scan Risks, Bonobos Show Language Connection, Revolutionary Brain Map Unveiled, Tolerogenic Cells Prevent Food Allergies, and more...
10:35
10:35
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10:35(0:10): Study Warns of Cancer Risks from CT Scans, Calls for Safer Radiation Practices (2:33): Bonobos' Complex Calls Suggest Language Links to Human Ancestors, New Study Shows (4:09): Largest Brain Map Created Using Film-Watching Mice, Revolutionizing Neuroscience (6:29): Breakthrough Discovery: Tolerogenic Dendritic Cells Key to Preventing Food A…
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