When you hear the words Alzheimer's disease, what do you think of? The truth is, the picture most of us have of the disease is incomplete. Alzheimer's disease doesn't start when someone starts to lose their memory. It actually starts years โ sometimes decades โ earlier. The Rethinking Alzheimer's Disease Podcast is an engaging, narrative-style podcast miniseries for those curious or motivated to learn about Alzheimerโs disease. Perhaps you have a family member with Alzheimerโs disease, or ca ...
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๐ง Macrophages Lost, ๐ Capillaries Impaired, ๐ Aging Accelerated
Manage episode 515588185 series 2740117
Content provided by MasterMedFacts LLC, Dr RR Baliga, MD, and MBA. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by MasterMedFacts LLC, Dr RR Baliga, MD, and MBA or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
๐ง Aging skin, fading flow. This 2025 Nature study uncovers how dermal capillary-associated macrophages (CAMs) decline with ageโpreceding microvascular dysfunction and impaired blood flow.
๐งฌ Using intravital imaging and macrophage fate mapping in mice (and validating in humans!), the authors reveal that CAMs are not replenished unless triggered by injury or CSF1. ๐ ๏ธ Fascinatingly, local CSF1โFc therapy restored CAMs and rejuvenated perfusion in aged skin. A compelling case for targeting tissue-resident immunity! ๐ฉธ
๐ doi:10.1038/s41586-025-09639-y
787 episodes
Share
Manage episode 515588185 series 2740117
Content provided by MasterMedFacts LLC, Dr RR Baliga, MD, and MBA. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by MasterMedFacts LLC, Dr RR Baliga, MD, and MBA or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
๐ง Aging skin, fading flow. This 2025 Nature study uncovers how dermal capillary-associated macrophages (CAMs) decline with ageโpreceding microvascular dysfunction and impaired blood flow.
๐งฌ Using intravital imaging and macrophage fate mapping in mice (and validating in humans!), the authors reveal that CAMs are not replenished unless triggered by injury or CSF1. ๐ ๏ธ Fascinatingly, local CSF1โFc therapy restored CAMs and rejuvenated perfusion in aged skin. A compelling case for targeting tissue-resident immunity! ๐ฉธ
๐ doi:10.1038/s41586-025-09639-y
787 episodes
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Similar to Dr RR Baliga's "Got Knowledge Doc" Podkast
When you hear the words Alzheimer's disease, what do you think of? The truth is, the picture most of us have of the disease is incomplete. Alzheimer's disease doesn't start when someone starts to lose their memory. It actually starts years โ sometimes decades โ earlier. The Rethinking Alzheimer's Disease Podcast is an engaging, narrative-style podcast miniseries for those curious or motivated to learn about Alzheimerโs disease. Perhaps you have a family member with Alzheimerโs disease, or ca ...
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Help me fill in the blanks of the practice of ED Critical Care. In this podcast, we discuss all things related to the crashing, critically ill patient in the Emergency Department. Find the show notes at emcrit.org.
…
continue reading
We take a critterโs eye view to explore how animal behavior parallels humans. Join comedians and science-lovers as we get inside the minds of animals
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continue reading
Emergency Medicine Cases โ Where the Experts Keep You in the Know. For show notes, quizzes, videos and more learning tools please visit emergencymedicinecases.com
…
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…
continue reading
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continue reading
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The Science Show gives Australians unique insights into the latest scientific research and debate, from the physics of cricket to prime ministerial biorhythms.
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