Best MasterMedFacts LLC Podcasts (2025)

1
🌟 A New Dawn in PAH: Sotatercept’s Big Win in PAH 🧬🏔️ 4:35

7h ago4:35

4:35

🚨 BREAKING: Sotatercept cuts risk by 76% in advanced #PAH! 💉 Targets activin signaling 🫁 Fewer deaths, transplants & hospitalizations 📉 HR 0.24 | Trial stopped early for efficacy ⚠️ Epistaxis, ↑Hgb, telangiectasia noted 🔬 A new era in pulmonary hypertension care! #ZENITHTrial #CardioTwitter 🫀📊 @doximity…

1
🫁 Beyond the Blow: Redefining COPD Risk with CT and Symptoms 🫁💡 3:12

5h ago3:12

3:12

🚨New COPD diagnosis alert!🫁 A multidimensional schema using CT 🖼️ + symptoms 😮‍💨 + spirometry 📉 identified high-risk patients missed by GOLD! 📈↑Mortality (HR 1.98) 📉FEV1 decline (–7.7 mL/y) 📊 Reclassified 15% w/o obstruction as COPD! 👉CT matters. #PulmTwitter #COPD #MedTwitter @doximityBy MasterMedFacts LLC

1
“🧬 One Shot, Six Months: Zilebesiran—an RNAi therapeutic Redefines BP Control” 2:58

23h ago2:58

2:58

🚨 New data! In the KARDIA-2 trial, 🧬 zilebesiran—an RNAi therapeutic—cut SBP by up to 12 mmHg when added to common antihypertensives 💊. One shot, 6 months of BP control! 📉 Promising for poor adherence. Mild AEs. #Hypertension #Cardiology #RNAi 🌍【JAMA 2025】By MasterMedFacts LLC

1
🧓➡️🧒 Anti-Aging Alchemy: A Tale of Two Geroprotectors-Trametinib & Rapamycin 4:41

1d ago4:41

4:41

🧬 Big win for longevity! A Nature Aging study shows that combining 💊 trametinib + rapamycin extends lifespan, reduces tumors, and tames inflammation in mice 🐭🔥 Dual geroprotectors = additive benefits without added toxicity 🛡️🕰️ Future of anti-aging? Watch this space 👀 #Aging #Longevity #Geroprotectors #Science 🧪 @doximity…

1
📉 Less is More: Light-Touch Stroke Care, Same Results 3:13

2d ago3:13

3:13

🧠💉 New Lancet study (OPTIMISTmain) shows low-intensity monitoring after thrombolysis in mild strokes may be just as safe as standard care! 💤 Less sleep disruption, 🧑‍⚕️ lighter nursing load, ⚖️ similar outcomes. Could this change global stroke care? 🌍🏥 #Stroke #Thrombolysis #OPTIMISTmain #NeurologyBy MasterMedFacts LLC

1
⚖️🚨 The Great Sedative Showdown: No Clear Winner, Just Tough Side Effects 3:33

3d ago3:33

3:33

🚨New A2B Trial in JAMA! Can 🧪dexmedetomidine or clonidine beat 💉propofol in sedating ICU patients on ventilators? ❌ No faster extubation ⚠️ More bradycardia & agitation ⚖️ Similar mortality Verdict: No clear winner—tailor sedation to patient needs 🛌👨‍⚕️ #CriticalCare #ICU #SedationTrialBy MasterMedFacts LLC

1
🧠➡️🩺🚀 “From Clot to Cure: Does TNK Boost EVT?” 4:41

3d ago4:41

4:41

🚨🧠 BREAKING: Tenecteplase before thrombectomy boosts chances of stroke recovery! 💉 Faster reperfusion 📈 Higher functional independence (mRS 0–2 at 90d: 52.9% vs 44.1%) ⚠️ Slight ↑ in sICH, but no major safety red flags 🧪 #BRIDGE_TNK trial rewrites the stroke playbook! #Stroke #Tenecteplase #NeuroTwitter…

1
Dr RR Baliga's Philosophical Discourses: Nagarjuna (India, c. 150 CE) – Founder of Madhyamaka School 3:52

3d ago3:52

3:52

Nāgārjuna (c. 150 – c. 250 CE) was an Indian Buddhist monk and philosopher, regarded as the founder of the Madhyamaka (Middle Way) school of Mahāyāna Buddhism. His most famous work, Mūlamadhyamakakārikā (Root Verses on the Middle Way), presents the concept of śūnyatā (emptiness) and the two truths doctrine, emphasizing dependent origination and rej…

1
🫀Low-Voltage Areas in AF, The SUPPRESS-AF Showdown! 3:36

4d ago3:36

3:36

📢 New RCT in Nature Medicine 🎯 Can zapping low-voltage areas (LVAs) reduce AF recurrence after PVI? 🔬 SUPPRESS-AF Trial 👥 342 pts with persistent AF 📉 1-yr AF/AT-free: 61% (PVI+LVA) vs 50% (PVI) ❌ Not statistically significant 🧠 Subgroup benefit in high-risk pts #EPeeps #AFib #CardioTwitter 🫀By MasterMedFacts LLC

1
Muscles, Memory, and Molecules 🧠💪🧬: Predicting Strength Decline with Alzheimer’s Biomarkers 3:36

4d ago3:36

3:36

🧠💪 Can blood biomarkers of Alzheimer’s predict who’ll lose muscle strength with age? In a 12-year study, higher p-tau, NfL & GFAP levels forecasted faster decline in grip & leg power — even before dementia onset. 🧬🪑✊ #Aging #Alzheimers #Sarcopenia #Biomarkers #LongevityBy MasterMedFacts LLC

1
🚶‍♂️ The Great Sit-Down: A Decade of Sitting Habits 2:52

5d ago2:52

2:52

📉 New JAMA study tracks U.S. #SedentaryBehavior from 2013–2023: 🪑 Sitting time fell from 7.1 to 5.9 hrs/day pre-COVID 🦠 But plateaued post-pandemic at 6.0 hrs/day 🚶‍♀️ Progress stalled—time to get moving again! #PublicHealth #NHANES #PhysicalActivity 🏃‍♂️📊🛋️By MasterMedFacts LLC

1
🐒 No Drama, Just Mama: Wild Chimps Show Secure Attachment 5:36

5d ago5:36

5:36

🐒 New study finds no disorganized attachment in wild chimpanzees! 🧠 Only secure & avoidant types observed—just like humans, but without the trauma. 🌿 Evolution favors calm, connected bonds. 📍Taï National Park, Côte d’Ivoire 🔗 Nature knows best. #PrimateScience #AttachmentTheory #Chimpanzees

1
“💡Tiny Pulse, Big Impact: Dissolving Pacemakers Powered by Light” 2:53

6d ago2:53

2:53

💡World’s tiniest pacemaker—smaller than a grain of rice! 🫀Leadless, wireless & bioresorbable 🔦 Powered by NIR light 🧬 Perfect for post-op pacing & TAVR 🌱 No wires, no scars, no removal! #MedTech #Cardiology #Bioengineering #Innovation @NatureBy MasterMedFacts LLC

1
“Cut the Cysteine, Burn the Fat, Jolt the Genome 🔪🔥🧬” 3:25

6d ago3:25

3:25

Cutting cysteine = 🔥 30% weight loss in 7 days! 🧬 Triggers stress pathways (ISR/OSR) ❌ CoA & glutathione drop 🔥 Browning fat, futile cycling, energy drain 💡 Reversible & promising for obesity research! #Metabolism #Obesity #AminoAcids #Science 🧪⚖️🧠By MasterMedFacts LLC

1
Battle of the Heart Valves: 🔍: Myval Matches, ACURATE Misses ❌, SAPIEN Stands Strong 💪 5:50

7d ago5:50

5:50

🚨 TAVI Trials Update! 🆚 COMPARE-TAVI 1: 🇮🇳Myval = 💪SAPIEN 3 in safety & efficacy 🆚 ACURATE IDE: ACURATE neo2 ❌not non-inferior to 💥SAPIEN/EVOLUT 📊 Valve wars intensify! #TAVI #HeartValve #Cardiology 🫀By MasterMedFacts LLC

1
“Not All Heat Is Equal: Science Behind the Chili Burn 🌡️🧠🌶️” 3:07

7d ago3:07

3:07

🌶️ Not all chili heat is created equal! Scientists found hidden compounds—like capsianoside I & roseoside—that cool the burn without changing flavor 🔬❄️ Your next spicy dish might be hot… but not hurt. #FlavorScience #Capsaicin #TRPV1 #FoodTech 🍽️🧠🔥By MasterMedFacts LLC

1
🚨 Tiny Twists, Big Clues: Vortices Reveal Chemotherapy’s Toll 4:05

8d ago4:05

4:05

📊 New study shows Topological Flow Data Analysis (TFDA) 🌀 detects early cardiac dysfunction in childhood cancer survivors—before LVEF or strain drop! 🔍 A game-changer in cardio-onc surveillance. #CardioOncology #TFDA #EchoRevolutionBy MasterMedFacts LLC

1
“COPD patients: Choked by Mucus Plugs? 📉💨🧪” 2:32

8d ago2:32

2:32

📉 Mucus plugs matter! In COPD, persistent or new plugs accelerate FEV₁ decline 🫁💨 🖥️ CT imaging tracks their impact 🚬 Smoking worsens the hit 👉 Clear the plugs, preserve the lungs! #COPD #LungHealth #NEJM #FEV1 #PulmonologyBy MasterMedFacts LLC

1
💥 Old Drugs, New Power: Amiloride vs Spironolactone in Resistant Hypertension 4:24

9d ago4:24

4:24

🩺 New hope for #ResistantHypertension! A 12-week RCT 🇰🇷 shows 💊 amiloride is noninferior to spironolactone in lowering SBP 📉 Fewer side effects, similar BP drop! But spironolactone may still reign 👑 for organ protection 🫀🧠 🧪 #Hypertension #Cardiology #JAMA2025By MasterMedFacts LLC

1
🧪 Precision for One, Promise for Many: CRISPR Meets the Clinic--A New Era in Rare Disease Therapy 6:43

10d ago6:43

6:43

🧬✨ A baby with deadly CPS1 deficiency (which results in elevated ammonia levels) gets a custom-made gene edit—delivered by lipid nanoparticles—in just 6 months! 🚀 Ammonia levels down, no hospitalizations, and hope up. N-of-1? More like Future-of-Many. 💡👶🔬 #GeneTherapy #PrecisionMedicine #RareDiseaseBy MasterMedFacts LLC

1
🔥 Smoldering Systems: Staging Systemic Metabolic Disorder Before It Ignites 3:40

10d ago3:40

3:40

🚨 New framework alert! Systemic Metabolic Disorder (SMD) gets a clinical staging makeover 🧬 From reversible risks 🌱 to systemic damage 🔥—this EAS consensus guides timely, targeted care 🎯 #MetabolicHealth #Cardiology #PrecisionMedicine #SMD 🩺📊By MasterMedFacts LLC

1
Dr RR Baliga's Philosophical Discourses: Pyrrho (Greece, c. 360–270 BCE) – Founder of Pyrrhonism 4:16

10d ago4:16

4:16

Pyrrho of Elis (c. 360–270 BCE) was an ancient Greek philosopher and founder of Pyrrhonism, a school of philosophical skepticism. He advocated for epoché (suspension of judgment) as a path to ataraxia (peace of mind). Influenced by his travels to India with Alexander the Great, Pyrrho believed that nothing could be definitively known and that by re…

1
🧬 Target ANGPTL3, Tame the Lipids, Transform the Risk 4:55

11d ago4:55

4:55

🧬 New hope for lipid warriors! Solbinsiran (siRNA) slashed apoB 🩸, TGs 🍟, LDL-C 💔 & liver fat 🫀 in just 205 pts with mixed dyslipidaemia. Safe ✅ Durable ✅ Quarterly dosing? Maybe ✅ Let’s talk outcomes! 🎯 #PROLONGANG3 #RNAtherapy #CardioTwitter #LipidLoweringBy MasterMedFacts LLC

1
🏥 Watch, Wait, or Wage War? The Prostate Cancer Playbook 3:41

11d ago3:41

3:41

🧔‍♂️ Prostate cancer is the most common cancer in US men. 🧪 PSA testing? 🔍 It’s all about shared decision-making. 🧬 From Gleason scores to PSMA-PET, precision reigns. 💉 ARPIs & ADT = survival gains in advanced disease. ⚖️ Screen smart. Treat right. Save lives. #ProstateCancer #MensHealth #Oncology 🧠💪…

1
Triglycerides, Trials, and Triumph 🚧📉🏆: The ANGPTL4 Story 5:32

12d ago5:32

5:32

🚨 New frontier in lipid-lowering! 🧬 Blocking ANGPTL4 with MAR001 slashed triglycerides & remnant cholesterol by >50% 🛡️ Safe, well-tolerated, no lymph node issues 💡 Promising for residual ASCVD risk Next step? Big trials, big answers! 📊🫀 #LipidScience #CardioTwitter #PrecisionMedicineBy MasterMedFacts LLC

1
Cracking the Code of Short Sleepers 🧠🔍😴 3:16

12d ago3:16

3:16

Why do some people sleep just 4 hours and feel great? 😴💪 A new study links the 🧬 SIK3-N783Y mutation to natural short sleep! Less sleep, more delta power 🧠⚡ 🚀🛌 #SleepScience #Genetics #SIK3 #ShortSleepersBy MasterMedFacts LLC

1
🔥 IL-6, Inflammation, and Irregular Beats: The Cytokine Cascade Driving Post-Op AFib 4:01

13d ago4:01

4:01

🫀 Post-op AFib? Blame IL-6! New @JClinInvest study shows IL-6 ➡️ STAT3 ➡️ CaMKII ➡️ RyR2 leak triggers post-op AFib. 🧬 Macrophage IL-6Rα is the match. 🧯 TTI-101 & KN-93 douse the flame. ⚡ Targeting IL-6 signaling = future Rx? #CardioTwitter #AFib #Inflammation #JCIBy MasterMedFacts LLC

1
Good Carbs, Great Life, Golden Years 🥦✨👵 4:24

13d ago4:24

4:24

🥦🍎 Want to age like fine wine? Choose high-quality carbs! In a 32-year study of 47K women, fiber-rich carbs (from 🌾, 🥗, 🌱) boosted odds of healthy aging 🧠💪🧘‍♀️ Refined carbs? Not so kind. #HealthyAging #NutritionMatters #WomensHealth 🧬📊💚By MasterMedFacts LLC

1
MRI Matters 🧲: Imaging the Silent Duo — Heart & Liver 🫀 4:19

14d ago4:19

4:19

🧠🫀🧫 New study in Nature Medicine shows that multiorgan MRI predicts both 💔 cardiovascular and 🩸 liver events. Cardiac (LVEF ≤50%) + Liver (cT1 ≥800ms) = 🚨 higher risk & earlier events. Integrated imaging = smarter prevention! 🔍📊 #Cardiology #Hepatology #MRI #MASLD #CVDBy MasterMedFacts LLC

1
💪 Immunotherapy Power Duo: Nivolumab + Ipilimumab vs. TKIs in HCC 4:17

14d ago4:17

4:17

🚀 New Breakthrough in Liver Cancer! 🌟 The CheckMate 9DW trial shows that Nivolumab + Ipilimumab significantly improves survival in unresectable #HCC compared to lenvatinib/sorafenib! 🧬💪 #Immunotherapy #CancerResearch #LiverCancer #Oncology 💉By MasterMedFacts LLC

1
💔 AF, Ablation, and Brain Clean-Up by Glymphatics: Fact or Fiction? 4:43

15d ago4:43

4:43

🧠💔 Atrial Fibrillation (AF) disrupts brain glymphatic function, leading to cognitive decline! 😓 Catheter ablation may help restore rhythm and brain clearance. More research needed! 📊 #Cardiology #BrainHealth #AF #Cognition 💡By MasterMedFacts LLC

1
🧠 Clearing the mind: How Glymphatics & Lymphatics Clear the Mind 2:32

15d ago2:32

2:32

🧠💡 New Insights! The brain isn’t as “immune privileged” as once thought! 🌊🔄 Glymphatics & meningeal lymphatics reveal how the CNS clears waste & connects to immunity. 🦠 Aging & neurodegeneration challenge this balance. #Neuroscience #Immunology #BrainHealth 🧬🚀By MasterMedFacts LLC

1
TR Troubles 🌟: Progress, Pitfalls, and Patient Selection 3:10

16d ago3:10

3:10

🚦 Tricuspid Regurgitation (TR) Troubles! 💔 Despite promising interventions, recent trials show no survival benefit. Patient selection & procedural success are key! 📝 Focus on quality of life, not just longevity. #Cardiology #HeartHealth #TRManagement 💙By MasterMedFacts LLC

1
Food as Medicine: Unleashing the Hidden Therapeutic Power of Nutrition Dark Matter 🌱💊 3:37

16d ago3:37

3:37

🌱💊 Unlocking the Power of Food! #NutritionDarkMatter holds 139,000+ molecules with therapeutic potential. 🍎 AI-driven research is paving the way for #PrecisionNutrition & innovative healthcare solutions! 🌟 #FoodAsMedicine #HealthRevolution 🚀By MasterMedFacts LLC

1
🚧 Stents vs Scalpels: The FAME 3 Face-Off 🩺⚔️ 4:17

17d ago4:17

4:17

🚨 FAME 3 at 5 years: FFR-guided PCI 🛠️ vs CABG 🫀 in 3-vessel CAD — no difference in death/stroke, but more MI & revascularization with PCI ⚠️. Heart team matters 🤝. #CardioTwitter #FAME3 #Revascularization 🩺📊By MasterMedFacts LLC

1
Dr RR Baliga's Philosophical Discourses: Zeno of Citium (Greece, c. 334–262 BCE) – Founder of Stoicism 3:28

18d ago3:28

3:28

Zeno of Citium (c. 334 – c. 262 BC) was a Hellenistic philosopher from Cyprus and the founder of Stoicism. His philosophy emphasized living in harmony with nature and practicing virtue to attain peace of mind (ataraxia). Zeno’s teachings influenced ethics, logic, and natural philosophy, laying the foundation for Stoicism’s prominence during the Rom…

1
🫀 Flow vs Form 🛠️: Guiding PCI with FFR or IVUS in the FLAVOUR II Trial 🎯 3:49

18d ago3:49

3:49

🚨 New from #FLAVOURII: Angio-FFR vs IVUS to guide PCI 🫀 🎯 Similar outcomes 📉 Fewer stents 🧠 Smarter decisions Is flow-based guidance the future? 🌍 #CardioTwitter #FFR #IVUS #Intervention 📰 Lancet 2025 | 📊 RCT | 🇨🇳 1839 patientsBy MasterMedFacts LLC

1
🚀 Next-Gen Weight Loss: Tirzepatide’s Winning Edge Over Semaglutide 3:07

19d ago3:07

3:07

🚀 Tirzepatide Triumphs! 💪 In a head-to-head trial, #Tirzepatide led to greater weight loss (-20.2%) compared to #Semaglutide (-13.7%) over 72 weeks! 📉🌟 Superior waist reduction too! #ObesityManagement #WeightLoss #GLP1 #GIP 🩺💊 #CardiometabolicHealth #ClinicalResearchBy MasterMedFacts LLC

1
Head Hits, Heart Risks: Concussions in Football Spike Cardiovascular Danger 🏈❤️ 3:19

19d ago3:19

3:19

🏈💥 Concussions in football don’t just hit the brain—they impact the heart too! 📈🫀 New study shows increased BP, arterial stiffness, and cardiac risks in NCAA athletes post-concussion. 🧠➡️❤️ #Cardiology #SportsMedicine #ConcussionRisk #HeartHealthBy MasterMedFacts LLC

1
🦠 Microbes, Mutations, and Malignancy: Unveiling the Gut–Blood Cancer Axis 💉 4:02

20d ago4:02

4:02

🧬 A molecule from aging gut bacteria—ADP-heptose—enters the bloodstream, activates ALPK1, and triggers NF-κB signaling, driving the expansion of mutant blood stem cells. 🦠🧓 This discovery links gut health to leukemia risk and reveals new targets like ALPK1 and UBE2N for cancer prevention. 💥🩸By MasterMedFacts LLC

1
Lower Blood Pressure, Sharper Minds, Less Dementia, Longer Lives 🧠💊🌾 3:42

20d ago3:42

3:42

🧠 Big win for brains & blood pressure! In a massive rural China trial (n=33,995), lowering BP with non-physician care ↓ dementia risk by 15%! A scalable, lifesaving model for LMICs. 🌾💊📉 #Dementia #Hypertension #GlobalHealthBy MasterMedFacts LLC

1
🌬️ Breathe Easy: Nasal Vaccines to the Rescue! 3:16

21d ago3:16

3:16

🚀🌬️ Nasal vaccines: A breath of fresh air in respiratory infection prevention! 🌟 Boosts mucosal immunity (SIgA & IgG) 💪, reduces transmission 🌡️, and protects against COVID-19, influenza, RSV, and more! #Vaccines #PublicHealth #Innovation 🦠💉By MasterMedFacts LLC

1
🧬 Silencing Risk: Lepodisiran vs Lp(a) 4:12

21d ago4:12

4:12

🚨 New hope for high Lp(a)! 💉 Lepodisiran, a long-acting siRNA, slashed Lp(a) by 94% with just 2 shots/year. 🔬 RNA precision meets cardiac prevention. 📉 Silent killer, silenced. #CardioTwitter #RNAtherapy #LipoproteinABy MasterMedFacts LLC

1
💨 Breathing Battles: Navigating COPD Phenotypes 4:15

22d ago4:15

4:15

🌬️🚶‍♂️ COPD comes in many forms! From chronic bronchitis 🪫 to emphysema 💨, frequent exacerbators 🚨, asthma-COPD overlap 🌪️, and eosinophilic type 🧫. Tailoring treatment to phenotype is key! #COPD #PrecisionMedicine #RespiratoryCareBy MasterMedFacts LLC

1
💊 TANDEM Triumph: Dual Power for LDL Cholesterol Reduction! 4:45

22d ago4:45

4:45

🚀 TANDEM Trial: Combining Obicetrapib & Ezetimibe for a powerful LDL reduction! 💊 ✅ -48.6% vs placebo, -27.9% vs Ezetimibe, -16.8% vs Obicetrapib 💪 Safe, effective, and oral! #Cardiology #LipidManagement #ASCVDBy MasterMedFacts LLC

1
Fungal Pharmacists, Fatty Liver, Future Frontiers 🧬🩸🍄 4:27

23d ago4:27

4:27

A gut fungus 🍄 (Fusarium foetens) secretes FF-C1 🧪, a metabolite that inhibits CerS6 and lowers ceramides 🩸—shielding mice from MASH 🛡️. Fungi aren’t just freeloaders—they may be our next therapeutic allies! 💊🧠 #Microbiome #LiverHealth #FungalTherapy #ScienceBy MasterMedFacts LLC

1
💪 Powerful Cholesterol Control: Obicetrapib in the Spotlight 🌟 2:44

23d ago2:44

2:44

🚀 Obicetrapib: A Breakthrough in LDL Lowering! 📉 Reduced LDL by 29.9% in high-risk patients (pBy MasterMedFacts LLC

1
Fat Chance! 🔬🧬 Middle-Age Spread Starts at the Cellular Level 3:13

24d ago3:13

3:13

Here’s a tweet with emojis based on the article: 🧬 Middle-age spread decoded! 🕰️ Visceral fat grows in midlife not from bigger cells—but new ones! 🎯 CP-A cells fire up fat formation via LIFR–STAT3 🔥 💊 Targeting them may halt metabolic disease before it starts. #Aging #Obesity #CellBiology #Metabolism 🧫 Would you like a version with a more humorous …

1
🔍📊🛡️ Detect, Decode, Defend: A New Era in Coronary Risk Prediction 3:31

24d ago3:31

3:31

🚨 New era in heart disease prediction! 🧬 + 🧪 + 🤖 = Meta-prediction model that beats PCE & QRISK3 📈 Detects hidden CAD risk in young, women & “low-risk” groups 🎯 Precision prevention just got personal. 🫀 Published in Nature Medicine #CardioTwitter #AI #Genomics #CADBy MasterMedFacts LLC

1
Dr RR Baliga's Philosophical Discourses: Epicurus (Greece, 341–270 BCE) – Founder of Epicureanism 3:16

25d ago3:16

3:16

Epicurus (341–270 BC) was an ancient Greek philosopher who founded Epicureanism, emphasizing the pursuit of a tranquil, happy life through ataraxia (freedom from fear) and aponia (absence of pain). His teachings combined atomism, ethics, and naturalistic theology, advocating simple living, friendship, and the rejection of superstition.…

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