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Stuck Surfactant, Freed by Science 🔬🧼➡️🫁

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Manage episode 502347623 series 2740117
Content provided by MasterMedFacts LLC and RR Baliga MD. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by MasterMedFacts LLC and RR Baliga MD or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

🚨 New in NEJM 🫁: The IMPALA-2 trial shows that inhaled molgramostim significantly improves gas exchange, quality of life, and exercise capacity in patients with autoimmune pulmonary alveolar proteinosis (aPAP)—a rare disease driven by GM-CSF autoantibodies.

💨 Say goodbye to whole-lung lavage—this is a bench-to-bedside success story 30 years in the making.

🔬 From GM-CSF knockout mice ➡️ inhaled cytokine therapy ➡️ regulatory-grade RCT.

🏆 A major win for translational respiratory medicine.

#Pulmonology #RareDiseases #GMCSF #AutoimmuneDisease #Molgramostim #PrecisionMedicine #TranslationalResearch #NEJM #aPAP #LungHealth #RCT #CytokineTherapy #BenchToBedside #InhaledTherapy 🧬🫁💊

  continue reading

673 episodes

Artwork
iconShare
 
Manage episode 502347623 series 2740117
Content provided by MasterMedFacts LLC and RR Baliga MD. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by MasterMedFacts LLC and RR Baliga MD or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

🚨 New in NEJM 🫁: The IMPALA-2 trial shows that inhaled molgramostim significantly improves gas exchange, quality of life, and exercise capacity in patients with autoimmune pulmonary alveolar proteinosis (aPAP)—a rare disease driven by GM-CSF autoantibodies.

💨 Say goodbye to whole-lung lavage—this is a bench-to-bedside success story 30 years in the making.

🔬 From GM-CSF knockout mice ➡️ inhaled cytokine therapy ➡️ regulatory-grade RCT.

🏆 A major win for translational respiratory medicine.

#Pulmonology #RareDiseases #GMCSF #AutoimmuneDisease #Molgramostim #PrecisionMedicine #TranslationalResearch #NEJM #aPAP #LungHealth #RCT #CytokineTherapy #BenchToBedside #InhaledTherapy 🧬🫁💊

  continue reading

673 episodes

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