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From Mom or Dad? It Makes a Difference whether Growth or Metabolsim π€π©βπΌπ¨βπΌ
Manage episode 499036226 series 2740117
π New in Nature: Groundbreaking study reveals how the origin of your genes β from mom π©βπΌ or dad π¨βπΌ β can push human growth π and metabolism π₯ in opposite directions!
𧬠Using data from 236,781 people across UK Biobank, Estonian Biobank, and MoBa, researchers uncovered 30+ parent-of-origin effects (POEs), many showing bipolar impacts β boosting traits when inherited from one parent, reducing them from the other.
βοΈ Findings support the parental conflict hypothesis: paternal genes tend to promote growth π, while maternal genes conserve resources π‘οΈ. These insights were invisible to standard GWAS, proving the power of family-rich biobanks in unlocking hidden genetic layers.
π Read the paper: https://doi.org/10.1038/s41586-025-09357-5
#Genomics #GWAS #Biobanks #ParentOfOrigin #Growth #Metabolism #PrecisionMedicine
640 episodes
Manage episode 499036226 series 2740117
π New in Nature: Groundbreaking study reveals how the origin of your genes β from mom π©βπΌ or dad π¨βπΌ β can push human growth π and metabolism π₯ in opposite directions!
𧬠Using data from 236,781 people across UK Biobank, Estonian Biobank, and MoBa, researchers uncovered 30+ parent-of-origin effects (POEs), many showing bipolar impacts β boosting traits when inherited from one parent, reducing them from the other.
βοΈ Findings support the parental conflict hypothesis: paternal genes tend to promote growth π, while maternal genes conserve resources π‘οΈ. These insights were invisible to standard GWAS, proving the power of family-rich biobanks in unlocking hidden genetic layers.
π Read the paper: https://doi.org/10.1038/s41586-025-09357-5
#Genomics #GWAS #Biobanks #ParentOfOrigin #Growth #Metabolism #PrecisionMedicine
640 episodes
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