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Content provided by MasterMedFacts LLC, Dr RR Baliga, MD, and MBA. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by MasterMedFacts LLC, Dr RR Baliga, MD, and MBA or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
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🧬 Aging Hearts, Arrested Cells: The Cellular Villain in CardioVascular Aging 🫀

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Manage episode 514701108 series 2740117
Content provided by MasterMedFacts LLC, Dr RR Baliga, MD, and MBA. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by MasterMedFacts LLC, Dr RR Baliga, MD, and MBA or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

🧬 Cellular senescence is more than just a marker of aging — it's a key driver of ❤️ cardiovascular disease. From the p53/p21 and p16/Rb axes to mTOR, SIRT1/6, NF-κB, and ROS/DDR, these molecular pathways halt cell division, fuel inflammation 🔥, and impair cardiac repair. Emerging data spotlight the roles of 💣 SASP, 🧓 senescent MSCs, and 🎯 microRNAs in accelerating vascular aging. Time to rethink how we tackle heart disease — at the cellular level. 🫀

📄 Based on: The role of cellular senescence in cardiovascular disease (doi:10.1038/s41569-023-00899-1)

#Cardiology #Senescence #CVD #Inflammaging #PrecisionMedicine #MolecularCardiology #HeartHealth

  continue reading

762 episodes

Artwork
iconShare
 
Manage episode 514701108 series 2740117
Content provided by MasterMedFacts LLC, Dr RR Baliga, MD, and MBA. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by MasterMedFacts LLC, Dr RR Baliga, MD, and MBA or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

🧬 Cellular senescence is more than just a marker of aging — it's a key driver of ❤️ cardiovascular disease. From the p53/p21 and p16/Rb axes to mTOR, SIRT1/6, NF-κB, and ROS/DDR, these molecular pathways halt cell division, fuel inflammation 🔥, and impair cardiac repair. Emerging data spotlight the roles of 💣 SASP, 🧓 senescent MSCs, and 🎯 microRNAs in accelerating vascular aging. Time to rethink how we tackle heart disease — at the cellular level. 🫀

📄 Based on: The role of cellular senescence in cardiovascular disease (doi:10.1038/s41569-023-00899-1)

#Cardiology #Senescence #CVD #Inflammaging #PrecisionMedicine #MolecularCardiology #HeartHealth

  continue reading

762 episodes

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