Welcome to "Total Innovation," the podcast where I explore all the different aspects of innovation, transformation and change. From the disruptive minds of startup founders to the strategic meeting rooms of global giants, I bring you the stories of change-makers. The podcast will engage with different voices, and peer into the multi-faceted world of innovation across and within large organisations. I speak to those on the ground floor, the strategists, the analysts, and the unsung heroes who ...
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Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the registrars of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs. Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au
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Core Loop is a podcast about video games and more. A bunch of guys that work in a game studio together take a break from work periodically to talk through the latest games they are playing. Most episodes are about a single game, but we'll change it up from time to time.
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Our podcast is simply about 2 buddies that talk about movies, games and other fun topics. We started by reviewing movies at work. Then we thought our content was good enough for others to listen to. We like to think we help our viewers by making the gym, walking the dog or car ride to work more pleasant and entertaining. We will be releasing an episode a week on Tuesday at 12:00AM as of now and we will keep the audience in the loop of any further changes. We are currently on Apple iTunes, Yo ...
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23: Pavlo Ryzhiy - The capital of failure
49:16
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49:16Pavlo Ryzhiy is a strategic advisor, catalyst, and integrator who specializes in connecting insights from strategy, innovation, business modelling, and organizational design to create solutions that others often overlook. Originally from Ukraine now based in Hamburg, Germany. Pavlo works with organizations that have previously failed at innovation …
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Episode 47 - Blood Banking with the Best | An Interview with Dr Joe Chaffin, MD (aka BBGuy)
1:07:41
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1:07:41Bashar was tasked with finding an expert to talk to about blood banking. He decided to cold-email the best transfusion-educator in the world who is probably responsible for hundreds if not thousands of haematology trainees understanding blood banking. Turns out he's an absolutely lovely guy who decided to spend an hour of his Monday morning chattin…
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Episode 46 - A PerPLEXing Journey | Introduction to Apheresis
33:48
33:48
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33:48Red cells. White cells. Platelets. Plasma. Proteins. By your powers combined I am Captain… Whole Blood? Wouldn’t it be so much easier if we could work with each of these blood components individually. After all, we have to get them in a bag to donate to people. Before we swear off transfusion for the time being, join the Bloody Minded Crew as we le…
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22: Juan Martin: Se puoi sognarlo, puoi farlo” (“If you can dream it, you can do it.”)
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40:05“Se puoi sognarlo, puoi farlo” (“If you can dream it, you can do it.”), Enzo Ferrari Dr. Juan Martin is an Intensive Care Consultant at Newham University Hospital NHS Trust, a Senior Lecturer at Queen Mary University of London, and a Medical Writer at Scienda Group. With over 17 years of experience as a successful innovator in the Wazoku solver eco…
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Episode 45 - Much A-B-O about Nothing | Transfusing A-B-O Mismatched Transplants with Dr Eoghan Molloy
59:17
59:17
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59:17Join our visiting expert Dr Eoghan Molloy - Multitalented transfusion medicine specialist and consultant haematologist at Cork University Hospital to teach us how to cross the ABO Rubicon and provide transfusion support in ABO mismatched transplantation. Visit the lab and see what happens to the forward and reverse group when you're in the middle o…
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Episode 44 - MAIPA Madness | FNAIT & Platelet Testing
39:12
39:12
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39:12FOUR Antibodies. THREE Animals. TWO Crying Haem Registrars. ONE TEST - The MAIPA. Actually maybe more than two crying haem registrars. How many antibodies are too many antibodies to have inside a lab test? One? That’s just a DAT. Two? A mere sandwich ELISA. But the Monoclonal Antibody Immobilisation of Platelet Antigens (MAIPA) - that’s not just th…
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21: John Winsor: Think Differently, Embrace Open
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50:45John is currently the executive-in-residence at Harvard Business School’s Laboratory for Innovation Science at Harvard (LISH), which studies AI and Workforce Transformation strategies, and founder and CEO of Open Assembly, a company that provides content, community, and strategic advising to organizations, people, and platforms to co-create the fut…
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Episode 43 - When your number’s not up | Platelet Refractoriness
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46:25
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46:25Have you ever looked at your wallet after a big night out and seen that all your dollars have been conjugated to alloantibodies and phagocytosed by macrophages? Then you know what it’s like to transfuse a platelet refractory patient! Join us as we take a tour of platelet refractoriness and do our best to find some HLA-matched dollars for rent this …
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Episode 42 - In The Lab: Rare Groups, Subgroups, Elutes and Fruit Loops | Advanced Blood Banking
48:41
48:41
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48:41Has this season been too simple? Want to up the difficulty? First of all you have issues, but second of all, welcome! It’s time to talk about all the things we don’t tell people about in the wider hospital - rare blood groups, subgroups, laboratory tips, tricks and more on this bumper In The Lab episode. Timestamps: 0:52 - How to get rich quick 3:5…
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20: Jayshree Seth: Innovation Thought Leadership
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40:20Jayshree Seth is a Corporate Scientist at 3M and currently holds 80 patents for a variety of innovations, with several additional pending. She joined 3M in 1993 after an MS and PhD in Chemical Engineering from Clarkson University, New York. She is a Distinguished Alumni Award recipient from her alma mater REC Trichy India, now NIIT Trichy, where sh…
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Episode 41 - Transfusion for Two | HDFN and Anti-D
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35:52What’s scarier than picking blood for one patient? Picking blood for TWO patients where one of them is inside the other (or only very recently outside). Obstetrics isn’t immune to the acronym train so join Nick, Cale and Bashar as we talk about HDFN, RhD prophylaxis and that OMG sensation that comes when looking after some of our smallest patients.…
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Episode 40 - On The Wards: The Antibodies of Wrath | IVIG and Rituximab Reactions
54:00
54:00
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54:00IVIG & Rituximab – both involve Antibodies – and both can lead to infusion reactions that you may be called to as a junior doctor. But where do these antibodies even come from? Why are we even giving these treatments? What are you meant to do when called to review the patient? Head back to the wards, get your cheese ready and welcome back consultan…
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19: Carla Lopez: Humanitarian Crowd Solving Part 2
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43:51Carla is a global health practitioner with 15 years of experience working on the stubborn issues that keep poor people in poverty. Her passion is to apply problem-solving approaches from human-centred design, behavioral insights, and the private sector to the development and humanitarian sector. She has worked in markets disrupted by the Ebola outb…
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Episode 39 - Tweaks and Tune-Ups | A Guide to Blood Product Modifications
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35:24Keen to augment your blood transfusion game but confused as to when, where and why? Join the Bloody Minded boffins as we cover all the major modifications to blood products you can order. More importantly, why you should and sometimes shouldn't bother ordering them. Have a sensible conversation with your blood bank after you listen to this episode.…
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Episode 38 - Infinity Products | Massive Transfusion Protocols
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37:59
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37:59Perfectly balanced, as all things should be. All that blood doesn’t just arrive when you snap your fingers together. The REALITY is you need the TIME and SPACE to thaw that frozen plasma and the strength of MIND to keep all the components in the right ratios. Only the chosen few with the POWER of transfusion medicine and the SOUL of the laboratory …
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18: Harry Sangree: Humanitarian Crowd Solving - Part 1
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46:00Harry is a career-long specialist in generating and applying innovation. Passionate about innovation to solve the hardest problems in seafreight and humanitarian causes. Three times a key member of the leadership teams of early-stage technology companies that aggressively innovated, including once as a co-founder. Two grew from pre-revenue to enter…
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Episode 37 - In The Lab: Red Cell Matchmaking | Group and Hold, Antibody Screen, Crossmatch
32:56
32:56
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32:56It’s an early trip to the lab this season to explore exactly how we safely match the blood in the bank to the patient on the ward. Follow your trusty hand-labelled group-and-hold tube as we unpack what actually goes into blood grouping, antibody screening and the final hurdle, the crossmatch! Timestamps 0:52 - Nick lives in squalor, surprising nobo…
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Episode 36 - What’s in the bag, Somerset, what’s in the bag? | Blood Products
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40:28
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40:28We’re back again to answer all of your questions- what’s exactly is a "unit" of blood and how do we go about giving it? What on earth is the difference between FFP and ELP and cryodepleted plasma? And what do each of them sound like, if you were to interpret them via a completely unnecessary collection of household objects? As always, we’ve got you…
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17: Tim Bernstein: Unlocking Impact from Open Innovation
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43:34
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43:34Tim helps large companies overcome internal hurdles to ignite externally sourced open innovation and technology acquisition, and facilitate technology transfer deals. He spends significant time delivering a wide range of IP and open innovation consulting services to clients, from open innovation system diagnostics to detailed technology and technol…
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Episode 35 - The Other Resus | Introduction to Blood Groups
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49:57
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49:57We’ve been out of line with the rest of #FOAM #MedEd podcasts for the longest time. Forget that haematology stuff, it’s time to talk about RESUS. Break out your adrenaline, it’s time to crack some chests and… wait what? You meant Rhesus? With an H? Oh right… okay. Put down those trauma shears as the only thing we’ll be cracking open are the ISBT Re…
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16. Paul Hobcraft: Building effective ecosystems
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45:53
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45:53Paul Hobcraft is a globally recognized expert in business ecosystem innovation and design, ranked among the top 50 global thinkers in Ecosystems and Renewable Energies. With extensive international experience spanning Asia, Europe, Middle East, and Africa, Paul helps organizations navigate the complexities of ecosystem-driven innovation and unlock …
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Episode 34 - On the Wards: I would do anything for blood – but I won’t do that | Transfusion Reactions
1:02:08
1:02:08
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1:02:08Do you fear – The Power of Blood? Have you been warned – You can’t Hurry Blood? Today we tackle all the ways Blood (and love) can go wrong. . . and how to manage it on the wards. Too cryptic? Join Bloody Minded's own consultant haematologist Dr Alison Chandler and the rest of the Bloody Minded Crew as we cover the many and varied reactions patients…
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15. Mike Todasco: The creative innovators journey
54:07
54:07
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54:07Mike Todasco spends his days thinking about how AI will change how we create Using generative tools like ChatGPT, Midjourney, and the ever-growing slate. He used to work at PayPal, focused on innovation Where he evangelized creativity to employees of every nation. At PayPal he also had many roles in the field of product From management to marketing…
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Episode 33 - CAR-T and Chromothripsis | Multiple Myeloma Review with Dr Christian Bryant
1:02:02
1:02:02
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1:02:02Myeloma beware, it's time to bring out the big guns. We are incredibly thankful to be joined by a peak predator of plasma cells, Dr. Christian Bryant. He is a consultant Haematologist at RPA in Sydney, has a PhD on the immunology of myeloma and is driven by a passion to improve the treatment and understanding of all things myeloma. TIMESTAMPS 2:18 …
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14. Dr. Nadya Zhexembayeva: Mastering Reinvention
38:37
38:37
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38:37Called ‘The Reinvention Guru’ (In Ventures magazine) and ‘The Queen of Reinvention’ (TEDx Navasink), Dr. Nadya Zhexembayeva is a business owner, educator, speaker and author -- specializing in reinvention. Nadya has helped such organizations as The Coca-Cola Company, ENRC PLC, IBM, CISCO, Erste Bank, Henkel, Knauf Insulation, Vienna Insurance Group…
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Episode 32 - Phagocytose. Pray. Love. | Haemophagocytic Lymphohistiocytosis (HLH)
41:19
41:19
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41:19Ferritin keeps climbing and you’re getting jumpy? Did you consult Haem and then they were bedside 5 minutes later? Ever had to donate your own blood to test the patient for something? Join Nick, Cale and Bashar as we unpack a very special bonus episode on another deadly TLA, HLH. TIMESTAMPS 3:24 - History of HLH 5:26 - What is a histiocyte? 7:44 - …
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Episode 31 - Advanced Myeloma Nursing with A/Prof Tracy King
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54:25
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54:25Thankfully, it's time for an actual expert to join us again on Bloody Minded! We are thrilled to be sitting down and chatting with A/Prof. Tracy King, Myeloma CNC from RPA Hospital in Sydney, Co-Founder and past president of the HSANZ Nursing Group. From convenient treatment schedulers to the side effects we should be thinking more about to many id…
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Episode 30 - Schnitzler’s List | Other Paraprotein Associated Diagnoses
36:18
36:18
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36:18All that glitters isn’t gold, and all that paraproteins isn’t myeloma. But if we’re not going to blame myeloma, then what else might be responsible? Hold on to your M-Spikes as we the Bloody Minded Team dive into the weird and wonderful world of paraproteins causing havoc in patients without myeloma. This episode isn’t for the faint of blood so get…
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Episode 29 - On The Wards: It's Getting Hot in Here | Febrile Neutropenia
54:13
54:13
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54:13Its time to hit the hot girl summer of haematology (we're in Australia after all) but also the hot boy winter and Autumn and Spring. Because our patients are hot all year round and sadly all night shift and possibly all throughout your ward round. Welcome to our next On The Wards episode looking at fevers in the haematology patient with a focus on …
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Episode 28 - In the Lab: Flow Cytometry, Mass Spectrometry & Cytogenetics in MM
42:26
42:26
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42:26Can’t get enough of obscure haematological lab chat, can you? Well we’ve got good news for you! Join us today as we delve even deeper into the arcane depths of flow cytometry, mass spectrometry and cytogenetics as they apply to myeloma. We promise we didn’t just make these words up. 02:23 - Flow cytometry: overview 04:01 - The flow cytometer: pract…
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Episode 27 - In The Lab: Electrophoresis, Immunoelectrophoresis and Serum Free Light Chain Assays
48:14
48:14
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48:14Thought you were free of myeloma acronyms? Don’t be ridiculous - this is the haematology lab! We were born in the acronyms, moulded by them. We didn’t see a complete word until advanced training and even then it was nothing but BLINDING. Your lab tests betray you because they belong to us… but in this episode we’ll let you in on some secrets. Join …
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13.Gijs van Wulfen: Breaking innovation barriers
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52:06Gijs van Wulfen (1960, based in Greece of Dutch origin) is a well-known global authority and trusted advisor on innovation, inspiring speaker, author of three innovation bestsellers, one of the top ten worldwide innovation bloggers, and a LinkedIn Influencer with 325.000+ followers. He is very driven to jump start innovation, because organisations …
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Episode 26 - Trip to the Congo | Amyloidosis Overview
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35:14
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35:14MGUS and Myeloma too simple for your tastes? Do you like vague presentations and biopsying many tissues in a sometimes wild goose chase? Why does Congo have all the birefringent apples? Go 'AAaah' as we TTRy to unpack ALl the problems that come with that most protean of disease - Systemic Amyloidosis! Timestamps 3:04 - Pathophysiology of Amyloid 6:…
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Episode 25 - Alphabet Soup | Overview of Myeloma Treatments
47:20
47:20
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47:20RVd, KTd, CyBorD, DVd, EloRd - Looks like the cat got on the keyboard. Oh wait, this is just the myeloma regimens in day therapy today. Come on a journey as we attempt (mostly successfully) to avoid drug trade names! Let go of your proteasome inhibitions, phenotype your red cells and let us modulate your understanding of what it is to treat myeloma…
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12. Ian Small: Building a water innovation ecosystem
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19:41Ian is the Innovation Lead at Expedition Engineering. Building on his networking skills and interest in new technologies Ian is working to connect people and teams to deliver amazing outcomes for our clients. Ian's primary focus at the moment is developing ways to accelerate the scale up and adoption of innovations as we aim for net zero carbon. Ia…
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Episode 24 - Blue Fried Eggs | Intro to Multiple Myeloma
28:35
28:35
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28:35== I do not like blue eggs and ham, I do not like them, Sam I Am. They crowd and clump, they grow too fast, Causing troubles that can last. They make my bones feel weak and sore, And through my kidneys they gnaw! I do not like blue eggs, you see, They're signs of something wrong with me. == Timestamps 3:35 - Recap of MGUS + smouldering myeloma 4:42…
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Episode 23 - Help I found a paraprotein | MGUS + The Spectrum of Plasma Cell Dyscrasias
31:48
31:48
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31:48Ordered something you shouldn’t have and accidentally found a paraprotein again? Shame on you, but now you have to do something with it. Maybe you were genuinely suspicious for myeloma. If incidentally discovered lab findings are leaving you smouldering, this is the episode for you! Join Nick, Cale and Bashar as they chat about the spectrum of plas…
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11.Tom Goodwin: Digital isn't a thing - it's everything
34:10
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34:10Tom Goodwin is a writer, speaker and advertising and media provocateur and consultant. He has been voted a top 10 voice in Marketing by LinkedIn, one of 30 people to follow on Twitter by Business Insider, and a 'must follow' by Fast Company. An industry commentator on the future of marketing and business, he is a columnist for TechCrunch and Forbes…
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Episode 22 - B is for B-Cell | Immunology 101
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35:24A is for Antibody. B is for B-cell. C is for Cryoglobul… wait no we’ve covered that already. If you struggle to tell your thymus from an isthmus, can’t see the humour in humoural immunity and think a bursa is just some fancy elbow cushion then THIS is the episode for you. Join the Bloody Minded Crew as they dust off their undergraduate immunology d…
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Episode 21 - On the Wards: Welcome to the Jungle | Your First Haem Ward Round
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44:54
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44:54Help! After a disastrous 3 way ward swap you now have to cover the haem ward as an intern in... 45 minutes time. If only there were some way you could get a crash course on everything you might need to know. Well are you in luck today! Join our new guest host Dr Alison Chandler for a whole new subtype of episodes, our new "On the Wards" series.“ Th…
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10.Greg Satell: How to keep your ideas alive
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34:31Greg Satell is the Co-Founder of ChangeOS, a transformation and change advisory. He is an international keynote speaker and bestselling author of Cascades: How to Create a Movement that Drives Transformational Changeand Mapping Innovation. His work has appeared in top publications like Harvard Business Review and Forbes. As a Lecturer at Wharton, e…
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Episode 20 - TMI about TLAs | TTP & PNH with Dr Danny Hsu
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43:24
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43:24Tired of listening to the three of us? Why not listen to an actual expert!? Today we're joined by Dr Danny Hsu, consultant haematologist, clinical lead of Immune Haematology & Therapeutic Apheresis at Liverpool Hospital, THANZ council member and all around top bloke to dig down into the nitty gritty of TTP and PNH. Any question you might have about…
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Episode 19 - In The Lab: Advanced Haemolysis Testing
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31:35
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31:35Have you been spending too much time outside of the lab lately? So have we! Come with us on a whirlwind tour through the high altitudes of thermal amplitudes, the chilly depths of cold agg titres, the bright lights of EMA testing, the flocculated wetlands of unstable haemoglobins (don’t ask) and more! All from the safety of the lab, of course. We d…
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Runar is CEO at YunoJuno, one of the most impactful companies to come out of the UK in recent years. Runar was previously the CEO of Depop (sold to Etsy for $1.6bn), scaling the company through multiple funding rounds from early stage startup to market dominance in the UK and successful expansion into US with millions of users. Prior to Depop, Runa…
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Episode 18 - Pretty Not Happy (with blood) | Paroxysmal Nocturnal Haemoglobinuria
21:22
21:22
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21:22Do you have a FLAER for the exotic? All at sea without your GPI-anchor? Come on a deep dive into the world of paroxysmal nocturnal haemoglobinuria - which isn’t really a disease of haemolysis at all but hey we're putting it here anyway and you can't stop us Timestamps 1:46 - What is PNH? Baby don't hurt me... 4:48 - Signs and Symptoms 7:27 - Pathop…
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Episode 17 - Enough about DAT | Approach to DAT Negative Haemolysis
36:30
36:30
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36:30MAHA TMA Gandhi once said a cell for a cell makes the whole body anaemic, or something along those lines. There’s so much more to DAT negative haemolysis than just DIC. Get out those buckets and put your sorting hats on - it’s time to go where detective Coombs never dared to and look over the DAT negative haemolytic processes. Timestamps 2:42 - App…
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8. Balaji Bondili: The Pixilated Future of Work
37:51
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37:51Balaji is a Product, P&L and Innovation leader with extensive experience ideating, incubating, developing customer-centric products and operating innovative product businesses. Deep industry expertise in Life Sciences, Healthcare, Innovation, Future of Work and Contingent Workforce. Currently teach product innovation and intrapreneurship at Harvard…
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Episode 16 - Brrrrr-eaking it down | Cold Haemolysis & Cryoglobulins
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38:33
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38:33Grab your hot beverage of choice and come out of the cold as we give you a warm welcome to the world of cold-dependent antibodies! No need to cry(o) as we unpack CAD vs CAS, get personal with PCH and gaze without alliteration at whatever the hell cryoglobulins are. If you're desperate for a medical reason to move to the tropics, this is the episode…
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Episode 15 - Antibodies behaving badly | Warm Autoimmune Haemolysis
29:32
29:32
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29:32Is there a glow surrounding your red cells? Things feeling heated in your reticuloendothelial system? An antibody to keep your bed warm at night? We don’t know where this is going either but grab a coconut and hop in the pool because we are excited to welcome you back with a chat about warm autoimmune haemolysis! Timestamps 00:57 - Introduction & C…
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Steve Rader serves as the Program Manager of NASA’s Center of Excellence for Collaborative Innovation (CoECI) and the NASA Tournament Lab (NTL), which are working to infuse challenge and crowdsourcing innovation approaches at NASA and across the federal government. CoECI focuses on the study and use of curated, crowdsourcing communities that utiliz…
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