This is The TriDot Podcast! We are here to educate, inspire, and entertain. We’ll talk all things triathlon, swim, bike, run, nutrition, recovery, & strength training, with expert coaches and special guests. So whether you are a triathlete training for a sprint, olympic, or IRONMAN event. Join the conversation, and let's improve together.
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Iron Index Podcasts
A tactical playbook for serious retail traders. Hosted by seasoned options professionals, this podcast delivers institutional-level insights on automated options trading with defined risk strategies and capital precision. Each episode is engineered for clarity and impact, covering everything from trade setup to allocation and risk control. You'll hear the logic behind every move, the rules behind consistent returns, and the mechanics professionals use to sidestep the costly mistakes most ret ...
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Join nabtrade for a fortnightly series, outlining strategies to build your wealth. For more insights, visit nabtrade.com.au/insights.
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Hello! Welcome to the Low Tox Life podcast - the place to bring your low tox life to life across all low tox pillars: Food. Body. Home. Mind. Planet. We cover it all to support you and your goals with some of the best minds in the world joining me each week. I'm Alexx Stuart, your host, and in 2009 I coined the term 'low tox' and started lowtoxlife.com. From there I've created 10 courses and had 2 books published (Low Tox Life and Low Tox Life FOOD; I've written countless research articles a ...
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The Blood Podcast summarizes content recently published in Blood, the most cited peer-reviewed publication in the field of hematology.
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In this How I Treat podcast episode, Laura Michaelis, MD interviews Sung-Yun Pai, MD about their recently published article in Blood journal "How I treat Wiskott-Alrich syndrome". They highlight recent updates in treatment, including new risk-benefit calculations due to safer treatments and longer follow-ups. Challenges include late diagnosis, lack…
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453. Gerald Quigley - Immune support + bringing herbal and nutritional support into your day-to-day without fear.
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58:06Why are we more susceptible to coming down with something like a cold or the flu at the turn of a season or change of humidity or temperature? And what really helps? Gerald Quigley joins me on the podcast this week. He’s a 50+ year pharmacist, a 40+ year herbalist, Fellow of the Naturopaths and Herbalists Association of Australia and Fellow of the …
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Use of Marstacimab for Prophylaxis in hemophilia A and B; matched-donor allogeneic CD19 CAR-T in adult B-ALL; a new prognostic index for T-cell cutaneous lymphomas
19:43
19:43
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19:43In this week's episode we'll learn about targeting the tissue factor pathway inhibitor with a monoclonal antibody to rebalance HEMOSTASIS in hemophilia A and B. In the phase 3 BASIS trial, the monoclonal antibody marstacimab reduced bleeding events, and was generally well tolerated, with no unanticipated side effects. After that: matched-donor allo…
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Cautiously optimistic – the outlook for the Australian economy
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34:29After years of anaemic growth, the outlook for the Australian economy may have quietly but steadily improved. But what’s on the horizon? Nab’s Chief Economist Sally Auld joins the podcast to discuss: Areas of strength and weakness in the Australian economy The outlook for inflation, rates and more Global challenges and opportunities Downside risks …
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Cash vs. Margin Account Basics for Options Trading
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9:24
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9:24Send us a text This episode provides an educational overview concerning the differences between cash accounts and margin accounts for options trading. A cash account mandates that the customer must possess the full amount of funds for any security purchased, precluding the use of leverage. Conversely, a margin account permits the broker to loan the…
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Tackling TriDot Workouts: MAV Shuttles, Fartleks, Threshold Repeats, Intervals, Decreasing Intervals, and Cruise Intervals
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1:01:40
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1:01:40Do you ever wonder why you're doing a certain workout, not just how? This week Vanessa Ronksley and Coach Ryan Tibball break down some of the most effective run workouts to help you train smarter, not just harder. We are starting with quality run sessions. Ryan and Vanessa dig into MAV Shuttles, Fartleks, Intervals, Threshold Repeats, and more! Exp…
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Epstein-Barr virus genomic variants in human disease states, somatic GATA1 mutations and leukemia in Down syndrome, and new definitions for high-risk multiple myeloma
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18:01In this week's episode, we’ll learn more about relationships between Epstein-Barr virus genomic variants and human diseases, including hematological malignancies; the presence and timing of somatic GATA1 mutations and their relationship to a Down syndrome-specific form of leukemia; and new definitions for high-risk multiple myeloma that emphasize t…
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452. IRON Deep dive: Too high, too low, tried ‘everything’ and still feel awful?
1:26:28
1:26:28
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1:26:28IRON: It’s a part 3 of sorts, as we’ve covered Iron twice on the show previously but given the questions that continue to come in: This is the show to round it all out thoroughly. We unpack: Iron - when it’s a friend, foe and how to get into a ‘healthier relationship with it’. Why your body might think it needs to protect you from iron Understandin…
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Decoding the VIX: How the "Fear Index" Calculates Market Movements and Prices
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9:00Send us a text The episode provides an educational overview of the VIX, which is the ticker symbol for the CBOE Volatility Index and is frequently called the "Fear Index" by investors. This index functions by measuring the implied volatility of S&P 500 options, which helps in determining if option pricing is relatively expensive or cheap. The VIX r…
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Chris Joye on where next for rates and finding value in fixed income
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34:34
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34:34Markets expect interest rates to trend lower, which has significant implications for equities – and the defensive and income sectors of your portfolio. With bank hybrids being phased out, where next for yield? Coolabah Capital CIO Chris Joye joins the podcast to discuss: The risks to the outlook for global interest rates Why he’s ‘very bullish’ the…
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20 Lessons from 20 IRONMAN Finishes
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1:04:53
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1:04:53“The finish line is not a final destination, but a breathtaking view that fuels the next journey.” In this episode, Coach Stephen Horan celebrates a major milestone: completing his 20th IRONMAN. With over 15 years of endurance racing Stephen takes time to reflect on the lessons learned from each finish line. From the power of community in training,…
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Review Series on Acute Lymphoblastic Leukemia (ALL)
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12:38In this Review Series episode, Associate Editor Dr. Hervé Dombret speaks with Dr. Mark Litzow about the latest immunotherapy advances for Acute Lymphoblastic Leukemia (ALL). The discussion highlights innovative treatments like blinatumomab and inotuzumab, which are showing remarkable success in clinical trials, including an 85% three-year survival …
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Azacitidine holds promise in VEXAS syndrome; a step forward in precision blood matching; identifying a new vulnerability in TP53-mutated AML
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18:58In this week's episode we'll learn about Azacitidine in VEXAS syndrome. Treatment can provide responses in patients with this complex autoinflammatory disorder. But relapse rates were high, so long-term therapy may be required to maintain disease control. After that: A step forward in precision blood matching. High-throughput array genotyping enabl…
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451. Want to keep joy and connection centre-stage in your relationship? Dr Kathryn Ford teaches us how.
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59:52What if, though, we knew the tools and techniques we needed to focus on to keep joy and connection centre-stage in our relationships? Dr Kathryn Ford has been working with couples to grow together for over 2 decades to do just that, and in this week’s show you will learn: Why having a vision of yourselves as a couple is important How becoming a cou…
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Bike to Run: Transform Your Triathlon T2
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1:04:12Transitions can make or break your race, and changing between sports are often where valuable seconds slip away. In this episode, we dig deep into the ins and outs of T2 with Coaches Elizabeth James and Ben Sommerville. From getting your legs ready for a run while wrapping up your ride and finding your transition spot fast to practicing the sequenc…
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Diffuse large B-cell lymphoma’s long-term effects on immune profiles, plasminogen activation and prevention of venous thromboembolism, and PARP inhibitors in hematological malignancies carrying epigenetic ...
18:31
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18:31In this week's episode we'll learn about persistent changes in immune profiles in patients who have had diffuse large B-cell lymphoma, or DLBCL, and other cancers; that plasminogen activation and plasmin activity do not appear to play a role in routine physiological prevention of venous thromboembolism, or VTE; and about a novel mechanism that make…
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450. Regenerative Farming insights for eaters and farmers with Margaret River Organic Farmer
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53:21
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53:21It’s a Farmer Insights show this week, designed to inspire eaters to upgrade their food sourcing practices and for farmers, whether organic or regenerative farming curious, to gain insights into how others are achieving success, saving money, transitioning, managing weeds and pests, and more. Lawson and Laura from Margaret River Organic Farm in Wes…
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A ‘brutal’ ASX reporting season – winners, losers and what’s next
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28:59While the ASX ended the month higher, share prices were surprisingly volatile in response to even modest beats and misses. So where is the value on the ASX, and what should investors be worried about? Atlas Funds Management Portfolio Manager Hugh Dive joins the podcast to discuss: Which ‘reasonable’ result saw its share price smashed The sectors re…
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Swim to Bike: Tidy-Up Your Triathlon T1
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1:04:53Transitions can make or break your race, and Transition 1 is often where valuable seconds slip away. In this episode, we take a deep dive into the ins and outs of T1 with Coaches Jeff Raines and Jenn Reinhart. From sighting the swim exit and navigating the chaos of the transition area, to smart gear staging and finding your bike fast, they share pr…
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“Ironing out” Tet2-mutant HSPCs; A CAR-T “license to kill” in T cell leukemia/lymphoma; insights on cHL genetics, through the lens of ctDNA
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20:43
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20:43In this week's episode, we'll learn about how TET2 is often mutated in myeloid malignancies and clonal hematopoiesis. In new work, expansion of Tet2-mutant HSPCs was dependent on Ncoa4, the cargo receptor mediating ferritinophagy. We’ll iron out the implications. After that: a double-oh-seven license to kill in T-cell leukemia/lymphoma. WU-CART-007…
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449. Decide what the next best version of yourself is: Here’s how, with Dr Shefali
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53:26
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53:26Dr. Shefali joins us this week: Clarity and Wisdom in 50 Minutes, looking at two aspects of psychology and personal development with the clinical psychologist and renowned best-selling author: 1️⃣ Conscious Leadership: Level up your life, starting with yourself! • Unlock your authentic self • Vision boarding done right - you may be focused on the w…
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Optimal Order Entry: 8 Tips for Faster Options Fills
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17:01Send us a text This episode provides eight key tips for options traders aiming to improve trade execution speed and pricing. The advice emphasises the importance of patience, suggesting that forcing trades is rarely beneficial. We also recommend using "odd" lot sizes for orders and "legging into" complex strategies by entering individual components…
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Nowhere but up – the S&P500 and why the index keeps winning
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39:49While some of the metrics for the world’s largest and deepest sharemarket remain extraordinary – new all-time highs, the highest level of concentration since the 1930s, company margins 50% above their long run average – the wins keep coming. So is it time to trim, add or hold? S&P Dow Jones Indices’ Howard Silverblatt has been covering the US for 4…
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8 Race-Day Breakfast Ideas From Triathlon Coaches
59:19
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59:19They say breakfast is the most important meal of the day, and on race day it's absolutely crucial. In this episode, we hear from 8 different triathlon coaches to see exactly what they eat before toeing the start line. From short course sprints to long course endurance events, we dive into how fueling strategies change and why topping off glycogen s…
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Targeting NPM1 in AML with a menin inhibitor; in primates, a CD137 ADC eliminates acute GVHD
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15:10In this week's episode we'll learn about targeting NPM1 in acute myeloid leukemia. Researchers report the first clinical evidence of a menin inhibitor inducing complete remissions in AML with a NPM1 mutation. This validates NPM1 as a new therapeutic target in AML, alongside FLT3, IDH1/2, and KMT2A. Also on the podcast: targeting CD137 to prevent gr…
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How I Treat Series on Iron Overload in Hematologic Disorders
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34:17Blood Editor, Dr. Thomas Coates interviews Dr. Emanuele Angelucci on his paper, "How I manage iron overload in the hematopoietic cell transplantation setting" which is featured in Blood's "How I Treat Series on Iron Overload in Hematologic Disorders". See the full How I Treat series in volume 145 issue 4 of Blood.…
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448. Eat 2 venison steaks a year to save the environment? The opportunity in addressing invasive species, with Tara Medina
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51:51A food system show with a difference today and I can’t wait to hear from our global audience how these issues play out where you live, too! What if eating a particular type of red meat - even just a couple of times per year - made a huge amount of environmental, economic and nutritional sense? Well, if you have an invasive species deer problem, lik…
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Send us a text This episode differentiates between historical volatility and implied volatility in options trading. Historical volatility quantifies past price fluctuations of a stock, often expressed as an annualised standard deviation of its movements over a specific timeframe, typically calculated using actual trading days. Conversely, implied v…
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Returning to Triathlon Training After an Injury
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1:05:02Whether it’s a nagging niggle or a major surgery, injuries are an almost inevitable part of long-term triathlon training. In this episode, Physical Therapy expert Dr. BJ Leeper and Professional Triathlete Elizabeth James share valuable insights to help you return to training stronger and smarter. We’ll cover smart strategies for easing back into tr…
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Early prediction of follicular lymphoma patients with poor survival; immune hotspots in aplastic anemia; role of allo-transplant for Hodgkin lymphoma in the checkpoint inhibitor era
19:49
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19:49In this week's episode we'll learn about how by combining PET response with circulating tumor DNA, or ctDNA, in newly treated patients with follicular lymphoma, investigators identify those patients likely to progress within 24 months of initial treatment, also known as POD24. After that: Immune hotspots in aplastic anemia. These newly identified h…
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Show 447. The Biology of Trauma: Uncover, Understand, and Heal with Dr. Aimie Apigian
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1:13:05Trauma: Have you read books full of all the reasons why trauma is linked to disease but felt a crucial piece missing? What to actually DO? This week, Dr. Aimie Apigian, double board-certified physician, trauma specialist, and author of the upcoming book The Biology of Trauma: How the Body Holds Fear, Pain, and Overwhelm, and How to Heal It, is goin…
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Option Moneyness: ITM, OTM, & ATM Explained
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15:54Send us a text This episode primarily explains option moneyness, categorising options as in-the-money (ITM), out-of-the-money (OTM), or at-the-money (ATM) based on the strike price's relationship to the underlying stock price. It clarifies how these classifications apply differently to call options and put options, offering examples to illustrate e…
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Exogenous CD19 stimulation in B-cell acute lymphoblastic leukemia treated with CD19 CAR T-cell therapy, sequential rapid immune-assay in heparin-induced thrombocytopenia diagnosis, and new survival prediction ...
18:42
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18:42In this week's episode, we’ll learn more about how exogenous CD19 stimulation affects CAR T-cell persistence in B-cell acute lymphoblastic leukemia treated with CD19 CAR T-cell therapy; new algorithms that incorporate sequential rapid immune-assays, intended to improve diagnosis of heparin-induced thrombocytopenia, and resource-adaptive survival pr…
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When Australians think property, they tend to think domestic housing, but the listed property market includes sectors well beyond the classic three bedroom home. With healthy yields and growth on offer, there’s a lot for investors to like – but don’t get caught in the hype for every hot sector. Resolution Capital portfolio manager Marco Colantonio …
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Fine-Tune Your Bike Fit (On Your Own!)
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1:04:38Since the bike leg is the longest part of any triathlon a proper bike fit is essential for performance, comfort, and injury prevention. While a professional fit is ideal, it's not always accessible. This week, Coaches Jeff Raines and Sion McIntosh join the show to share practical advice on how to fine-tune your bike fit at home. You'll learn how to…
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How I Treat series on Acute Myeloid Leukemia
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42:55In this episode, Associate Blood editor Dr. Selina Luger leads a discussion with Drs. Courtney DiNardo, Eunice Wang, Andrew Wei and Gail Roboz about the advances in treatment options for Acute Myeloid Leukemia (AML). The conversation highlights new combinations like Venetoclax-azacitidine, challenges with differentiation syndrome, and emerging stra…
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446. Unlock Nature's Medicine Cabinet with Herbalist and Author, Rachelle Robinett.
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1:04:14Herbs: Do you have the confidence to use them in certain situations? Do you only turn to herbal supplements when things are wrong? This week with clinical herbalist and author, Rachelle Robinett, we are growing our herbal medicine vocab. Rachelle Robinett is a Clinical Herbalist, writer, educator, and thought-leader and is here to inspire you close…
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Send us a text This episode explains how "Greeks" measure an option's sensitivity to market variables. These "Greeks" are Delta, Gamma, Theta, Vega, and Rho, each representing a specific influence on an option's price. Delta indicates price change based on underlying stock movement, while Gamma measures the rate of change in Delta. Theta quantifies…
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8 Ways Triathletes Lose Time (And How to Fix Them)
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1:04:28In triathlon every second matters and even small mistakes can cost you big on race day. We’ve brought in two coaches, Matt Sommer and Matt Bach, to help you reclaim lost time and get the most out of your fitness on race day. In this episode, we dive into practical strategies for saving time before, during, and after the race. From course prep and g…
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445. Herbal Medicine 2.0: Rebuilding our health and our planet from the soil up with Ric Scalzo
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59:12Do you take any medicinal herbs? This week we have an hour of power with pioneer herbalist, entrepreneur and now regenerative farmer and research philanthropist, Ric Scalzo. Some of the parts to the show: • Ric's journey from philosophy student to herbal medicine and naturopathy • Fascinating insights on herbs like hawthorn, wormwood and schisandra…
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Daratumumab maintenance in newly-diagnosed, transplant-eligible multiple myeloma; the role of neutrophils in myeloproliferative neoplasms; and novel genetic loci associated with the risk of heavy menstrual ...
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15:11In this week's episode, we’ll learn more about the effects of daratumumab maintenance on minimal residual disease in patients with newly diagnosed, transplant-eligible multiple myeloma; the role of neutrophils in the pathophysiology of myeloproliferative neoplasms; and a genome-wide association study that identified novel genetic loci associated wi…
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9 Lessons Our Triathlon Coaches Learned At The Races
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52:51As experienced Coaches Jeff Raines and Elizabeth James have seen it all on race day—and this week, they're sharing the biggest lessons they've learned while spectating on race day. From practical advice on bike maintenance and travel planning to embracing the race-day atmosphere and soaking in the finish-line moment, they’re dishing out the same ti…
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444. The Modern Mental Health Tool Kit - what’s working, what to avoid with Dr Katelyn Kalstein
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1:00:45Mental Health - The more we know, the more overwhelmed and confused we are? That’s not how it’s supposed to be. Enter Dr Katelyn Kalstein and this powerful conversation I had the privilege of hosting. Dr. Kalstein, a naturopathic doctor, acupuncturist, psychotherapist and ketamine-assisted therapist on the cutting edge of integrative treatments, pr…
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Gold, iron ore, lithium and more - the outlook for key resources in this market
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57:16The gold price is soaring, lithium may be staging a comeback, iron ore has somewhat disappointed. The materials sector offers a range of large and small cap opportunities for astute investors, but the outlook for each sector is diverging. To help make sense of the landscape, MineLife’s Gavin Wendt joins the podcast to discuss: Why the rise of the C…
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Hematopoietic stem cells with enhanced transplantability, ruxolitinib for refractory macrophage activation syndrome, and magrolimab in newly diagnosed acute myeloid leukemia
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18:56
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18:56In this week's episode we'll learn more about enhanced transplant characteristics; targeting the JAK-STAT pathway with ruxolitinib in patients with adult-onset Still’s disease and macrophage activation syndrome; and a pair of trials demonstrating lack of benefit for the anti-CD47 monoclonal antibody magrolimab in newly diagnosed acute myeloid leuke…
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Send us a text This episode explores the concept of automated options trading, addressing common concerns about its safety and efficacy. It identifies key risks such as technical failures, market volatility, and strategy flaws, while also offering methods to mitigate these dangers, emphasising the importance of reliable brokers and defined-risk str…
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Conquer Every Type of Triathlon Swim Start
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1:01:24Whether it’s a wave, rolling, or mass start, how you begin your triathlon swim can make all the difference. In this episode, coaches Joanna Nami and Ryan Tibball break down every type of open water swim start and share expert strategies to help you launch with confidence. You’ll get practical tips for staying calm, starting strong, and settling int…
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443. The Vagina Business: Prioritise women for their health and for business! Marina Gerner
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58:05🚨 TABOO ALERT: Vaginas 🚨 Giggles. Squirms. Shushes. Why are we STILL so awkward about women's health and body parts? 🔍 Journalist Marina Gerner investigates: • Who's REALLY innovating in women's health? • Is the tide finally turning on shame and taboo? Prepare to fist pump... or facepalm 🤦♀️this show. ALSO, MYTH-BUSTING ALERT: "Femme tech" isn't a…
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A JAK inhibitor for CRS and ICANS prevention; ChAdOx1-platelet interactions and post-vaccination arterial thrombosis; lineage switch, an emerging mechanism of leukemia relapse
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18:51In this week's episode, we'll learn about a JAK inhibitor to prevent complications of CD19-directed CAR T-cell therapy. In a phase 2 study, itacitinib was well tolerated and demonstrated promising reductions in the incidence of cytokine release syndrome and neurotoxicity. After that: investigators report direct interactions between ChAdOx1 and plat…
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Option Profit & Loss Diagrams: P&L Secrets Explained
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13:46Send us a text This episode focuses on understanding option profit and loss (P&L) diagrams. These diagrams are visual representations that illustrate how an options strategy's profitability changes based on the underlying asset's price at expiration. The hosts explain how to interpret these graphs, identifying key elements like break-even points, m…
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