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TWiST 500 interviews with Cortical Labs, Turing, AND Mercor | E2159
Manage episode 497807451 series 3371599
Content provided by Jason Calacanis. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Jason Calacanis or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Today’s show:
Alex is back with three more awesome interviews with founders on the bleeding edge of innovative tech.
- Dr. Hon Weng Chong walks us through the basics of biological computing and Cortical Labs’ first-ever commercial computer running on living human cells.
- Turing founder Jonathan Siddarth unpacks the secrets of LLM benchmarking, and explains why even our most advanced tests need to get much much harder right away.
- Finally, Mercor founder Brendan Foody on how AI is about to reinvent the hiring process, and marrying the effectiveness of recruiters with the ease of online job boards.
It’s three — count ’em, three — can’t miss TWiST interviews guaranteed to make you smarter
Timestamps:
(0:00) OpenAI’s GPT-5: When is it coming out? Is it going to be TOO smart?
(08:06) Cortical Labs’ Hon Weng Chong on the electric connection between neuroscience and machine learning
(10:20) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!
(11:27) Show Continues…
(15:17) The extreme difficulty of going from the lab to a shippable product
(20:00) .TECH: Say it without saying it. Head to www.get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.
(21:05) Show Continues…
(28:15) Why data is a factor of time
(29:52) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits
(31:16) Show Continues…
(42:44) Turing CEO Jonathan Siddarth explains why it’s so important to keep benchmarking our LLMs
(47:24) What it means when a model “saturates” a test, and why benchmarks need to get HARDER
(50:22) What happens with the LLMs can answer all of our smartest questions?
(53:44) AI Agents train in gyms? Wait, really?
(01:01:33) Coding teaches models how to think, and more training mysteries don’t understand
(01:03:11) Brendan Foody from Mercor explains the “matching problem” that makes hiring such a pain
(01:07:02) How Mercor combines a job board’s distribution with the value of a recruitment agency
(01:10:49) Brendan recalls building his first AI interviewer in his college dorm
(01:20:16) Mercor has the opposite of a retention problem and crazy growth
Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com
Check out the TWIST500: https://www.twist500.com
Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp
Follow Lon:
Follow Alex:
LinkedIn: https://www.linkedin.com/in/alexwilhelm
Follow Jason:
LinkedIn: https://www.linkedin.com/in/jasoncalacanis
Thank you to our partners:
(10:20) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!
(20:00) .TECH: Say it without saying it. Head to www.get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.
(29:52) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
Check out Jason’s suite of newsletters: https://substack.com/@calacanis
Follow TWiST:
Twitter: https://twitter.com/TWiStartups
YouTube: https://www.youtube.com/thisweekin
Instagram: https://www.instagram.com/thisweekinstartups
TikTok: https://www.tiktok.com/@thisweekinstartups
Substack: https://twistartups.substack.com
Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
1283 episodes
Share
Manage episode 497807451 series 3371599
Content provided by Jason Calacanis. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Jason Calacanis or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Today’s show:
Alex is back with three more awesome interviews with founders on the bleeding edge of innovative tech.
- Dr. Hon Weng Chong walks us through the basics of biological computing and Cortical Labs’ first-ever commercial computer running on living human cells.
- Turing founder Jonathan Siddarth unpacks the secrets of LLM benchmarking, and explains why even our most advanced tests need to get much much harder right away.
- Finally, Mercor founder Brendan Foody on how AI is about to reinvent the hiring process, and marrying the effectiveness of recruiters with the ease of online job boards.
It’s three — count ’em, three — can’t miss TWiST interviews guaranteed to make you smarter
Timestamps:
(0:00) OpenAI’s GPT-5: When is it coming out? Is it going to be TOO smart?
(08:06) Cortical Labs’ Hon Weng Chong on the electric connection between neuroscience and machine learning
(10:20) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!
(11:27) Show Continues…
(15:17) The extreme difficulty of going from the lab to a shippable product
(20:00) .TECH: Say it without saying it. Head to www.get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.
(21:05) Show Continues…
(28:15) Why data is a factor of time
(29:52) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits
(31:16) Show Continues…
(42:44) Turing CEO Jonathan Siddarth explains why it’s so important to keep benchmarking our LLMs
(47:24) What it means when a model “saturates” a test, and why benchmarks need to get HARDER
(50:22) What happens with the LLMs can answer all of our smartest questions?
(53:44) AI Agents train in gyms? Wait, really?
(01:01:33) Coding teaches models how to think, and more training mysteries don’t understand
(01:03:11) Brendan Foody from Mercor explains the “matching problem” that makes hiring such a pain
(01:07:02) How Mercor combines a job board’s distribution with the value of a recruitment agency
(01:10:49) Brendan recalls building his first AI interviewer in his college dorm
(01:20:16) Mercor has the opposite of a retention problem and crazy growth
Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com
Check out the TWIST500: https://www.twist500.com
Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp
Follow Lon:
Follow Alex:
LinkedIn: https://www.linkedin.com/in/alexwilhelm
Follow Jason:
LinkedIn: https://www.linkedin.com/in/jasoncalacanis
Thank you to our partners:
(10:20) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!
(20:00) .TECH: Say it without saying it. Head to www.get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.
(29:52) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
Check out Jason’s suite of newsletters: https://substack.com/@calacanis
Follow TWiST:
Twitter: https://twitter.com/TWiStartups
YouTube: https://www.youtube.com/thisweekin
Instagram: https://www.instagram.com/thisweekinstartups
TikTok: https://www.tiktok.com/@thisweekinstartups
Substack: https://twistartups.substack.com
Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
1283 episodes
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Similar to This Week in Startups
Africa-focused technology, digital and innovation ecosystem insight and commentary.
…
continue reading
Show notes are at https://stevelitchfield.com/sshow/chat.html
…
continue reading
The director’s commentary track for Daring Fireball. Long digressions on Apple, technology, design, movies, and more.
…
continue reading
Download This Show is your weekly guide to the world of media, culture, and technology. From social media to gadgets, streaming services to privacy issues. Each week Rae Johnston and guests take a fun, deep dive into how technology is reshaping our lives.
…
continue reading
WSJ’s Bold Names brings you conversations with the leaders of the bold-named companies featured in the pages of The Wall Street Journal. Hosts Tim Higgins and Christopher Mims speak to CEOs and business leaders in interviews that challenge conventional wisdom and take you inside the decisions being made in the C-suite and beyond.
…
continue reading
The power of Data is undeniable. And unharnessed - it’s nothing but chaos. Making data your ally. Using it to lead with confidence and clarity. Host Jess Carter is solving problems in real-time to reveal what’s possible. Helping communities and people thrive. This is Data Driven Leadership, a show brought to you by Resultant.
…
continue reading
Android Backstage, a podcast by and for Android developers. Hosted by developers from the Android engineering team, this show covers topics of interest to Android programmers, with in-depth discussions and interviews with engineers on the Android team at Google. Subscribe to Android Developers YouTube → https://goo.gle/AndroidDevs
…
continue reading
This is the audio podcast version of Troy Hunt's weekly update video published here: https://www.troyhunt.com/tag/weekly-update/
…
continue reading
We help founders make something people want.
…
continue reading
Three nerds discussing tech, Apple, programming, and loosely related matters.
…
continue reading
Player FM - Podcast App
Go offline with the Player FM app!
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