Best Jason Calacanis Podcasts (2025)

1
Discord’s Power Move, Slate’s Modular EVs & the “Act for Private Gain” | E2117 1:25:51

1d ago1:25:51

1:25:51

Today’s show: Jason, Alex, and Lon break down today’s top tech and startup stories — from Slate Auto’s customizable $25K EV truck to Discord’s major leadership shakeup ahead of a potential IPO. They also cover Uber’s self-driving push with Volkswagen, Perplexity AI’s aggressive growth moves, and why value-driven products are winning in a tough econ…

1
Cursor’s $300M ARR, Uber’s FTC Battle, and Office Hours with GoShare | E2116 1:02:26

22m ago1:02:26

1:02:26

Today’s show: Jason, Alex and Lon unpack the FTC’s lawsuit against Uber and what it could mean for subscription UX, break down how AI startup Cursor is growing faster than almost any SaaS company in history, and discuss how dark patterns, consumer trust, and regulatory scrutiny are reshaping product design. They also touch on the future of big tech…

1
Robot Lifeguards, TapCheck’s Payday Play & Thalamus’s Wild Market Share | E2115 1:16:58

1d ago1:16:58

1:16:58

Today’s show: Jason and Lon break down the biggest stories in tech and startups this week: OpenAI’s new models are powerful but glitchy, Meta’s internal docs hint that Zuck knows the Facebook friends graph is toast, and fintech startup TapCheck might actually be doing some good. Plus, robot lifeguards and humanoid races — the wildest videos of the …

1
LMArena Goes Startup, AI App Wars Begin, Scott Bair’s Design Playbook | E2114 1:01:22

4d ago1:01:22

1:01:22

Today’s show: Jason, Alex, and Lon discuss the rise of LMArena as it spins out into a full-fledged startup, what that means for AI benchmarking, and how it could monetize its growing community. They also dive into the emerging value of application-layer AI startups and why OpenAI’s acquisition spree is just beginning. Plus, branding expert Scott Ba…

1
AI Progress and Impact on Ecosystem Players with CapitalG’s Jill Chase | AI Basics with Google Cloud 25:28

6d ago25:28

25:28

In this episode of AI Basics, Jason sits down with CapitalG partner Jill Chase to break down how AI is reshaping the startup ecosystem — from founders to investors to incumbents. They cover how CapitalG (Alphabet’s independent growth fund) thinks about the AI stack, why speed alone isn’t enough for startups today, and how to build durable advantage…

1
Cuts CEO Talks Tariffs, Figma's IPO Buzz, and a Nerd Crawler Update | E2113 1:06:53

11d ago1:06:53

1:06:53

Today’s show: Jason, Alex, and Lon discuss Figma’s surprise IPO filing following its $1B breakup from Adobe, OpenAI’s quiet push into social networking through a Sora image-sharing feed, and how sweeping new China tariffs are wreaking havoc on ecommerce companies—impacting jobs, supply chains, and pricing. Plus: the Substack vs. Patreon battle heat…

1
Vertical AI Innovations: Abacus LLM in Finance & Synthesia's Video Avatars | E2112 1:07:35

8d ago1:07:35

1:07:35

Today’s show: Alex interviews founders from Abacus and Synthesia—two companies leading the charge in vertical AI. Abacus is deploying on-prem LLMs to banks and insurers with a focus on data control, accuracy, and integration with legacy infrastructure. Synthesia just hit $100M ARR by helping 70% of the Fortune 100 turn internal documents into scala…

1
HuggingFace Buys Pollen Robotics, DHH & Bezos Founder Advice & a JCal Origin Story | E2111 1:03:11

13d ago1:03:11

1:03:11

Today’s show: In this episode, Jason, Alex, and Lon dive into Blue Origin’s all-female celeb spaceflight (yes, Katy Perry sang on reentry), Hugging Face’s unexpected move into robotics, and Jack Dorsey’s wild take that we should “delete all IP law.” Plus, they break down Figure AI’s eye-popping $39B valuation, the risks of SPVs, and what founders a…

1
Palantir's Fellowship, Coco Robots & Startup Office Hours | E2110 1:08:53

11d ago1:08:53

1:08:53

Today’s show: We dive into the latest tech and startup news — including Palantir’s bold new fellowship program that challenges the traditional college path, and DoorDash’s rollout of burrito-delivering Coco robots in LA and Chicago. We debut our new segment “Tips from the Trenches,” focused on how to land your first customers, and wrap up with two …

1
70mph Drone Deliveries, 125% Tariffs & What $10M Exits Really Mean | E2109 1:07:14

18d ago1:07:14

1:07:14

Today’s show: Jason, Alex, and Lon talk about stories reshaping the startup world: 70mph drone deliveries are officially live in Dallas, with Zipline and Walmart promising groceries “as the crow flies” in under 5 minutes. Meanwhile, Trump slaps a 125% tariff on China and hints at a global economic shakeup — Jason warns founders to brace for layoffs…

1
#21 Reach Neuro: Spinal Stimulation to Restore Movement In Upper Limb Post-Stroke - CEO Marc Powell 31:37

14d ago31:37

31:37

Free Neurotech Newsletter: https://neurotechnologynews.beehiiv.com/subscribe Key Moments: 0:00 Introduction 3:17 Initial Interest in Neuroscience 4:50 Origin Story of Reach Neuro 6:16 Reach Neuro’s Avantis Platform 11:12 Reach Neuro Competitors 14:40 Navigating FDA Regulations and Breakthrough Device Designation 19:02 Research Tools and Product Dev…

1
Economic Chaos, More Pitch Madness & the Shopify AI Manifesto | E2108 1:27:07

15d ago1:27:07

1:27:07

Today’s show: Jason and Alex unpack a wild week in tech and the markets — including a fake tweet that moved $4 trillion and Trump’s latest tariff talk. Lon jumps in for another round of Founder Fridays Pitch Madness, where four early-stage startups compete for a spot in the Elite Eight. Plus, Alex chats with Sunny Khamkar, CEO of MenuData, about ho…

1
Rippling Targets $16B, Market Chaos, TikTok Timeout, and Office Hours | E2107 1:31:40

22d ago1:31:40

1:31:40

Today’s show: Jason and Alex dive into the startup world’s latest chaos — from Nasdaq’s slide and Trump’s tariffs to Klarna’s IPO pause and Rippling’s $16B target. They break down what founders really need to know: tightening CIO budgets, longer sales cycles, but easier hiring. Plus, TikTok’s ban gets another delay (with Bezos possibly lurking?). I…

1
Spycraft in SaaS, Rabbit’s Comeback, and Startup Pitch Madness | E2106 1:12:54

24d ago1:12:54

1:12:54

This Week in Startups is brought to you by… Kyte - TWIST Listeners: Go to https://kyte.com/ and download the Kyte app today. Use code JASON to save 10% on your first rental. Atlassian - Head to https://www.atlassian.com/startups/twist to see if you qualify for 50 free seats for 12 months. Lemon.io - Get 15% off your first 4 weeks of developer time …

1
M&A Mania, Palantir Meme Crash + Office Hours with Hookhub | E2105 1:16:40

26d ago1:16:40

1:16:40

Today’s show: Circle gears up for its IPO and the stablecoin wars heat up, Palantir’s meme stock status gets a reality check, and they riff on a possible Uber + DoorDash merger and whether AI should train on Substack content. They react to Sequoia partner Andrew Reed’s inside take on fund dynamics, laugh at a brutal VC meme, and wrap with “Office H…

1
AI Revolution Gains, Non-Consensus Startups & Prosperous AI | E2104 1:13:39

29d ago1:13:39

1:13:39

Today’s show: Jason, Alex, and Lon cover everything from wild political headlines to big moves in AI and venture. They kick things off with the surprising Trump pardon of Trevor Milton, the disgraced Nikola founder, and break down CoreWeave’s rocky IPO debut. Then, Jason and Alex sit down with Mariano Apodaca, founder of Prosperous AI, to talk abou…

1
11x in Trouble and China's AI Acceleration | E2103 1:14:04

1M ago1:14:04

1:14:04

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1
23andMe BANKRUPT, Saylor Still Buying Bitcoin, + Founder Interviews | E2102 1:36:15

1M ago1:36:15

1:36:15

Today’s show: In this episode, Alex and Lon kick things off with the latest tech news — including 23andMe’s dramatic collapse, MicroStrategy’s half-million Bitcoin haul, and whether we’re finally seeing a rebound in startup M&A. Then they sit down with three standout founders building the future across AI chips, data privacy, and healthcare. First …

1
Fact-Checking Mark Rober, and the Fall of TechCrunch | E2101 1:01:00

1M ago1:01:00

1:01:00

Today’s show: Jason, Alex, and Lon break down a subreddit question: A founder builds 100% of the product, is promised equity—and now he’s being pushed out. We break down exactly what he should do next. Plus, YouTuber Mark Rober’s viral Tesla test gets fact-checked by a small creator, and the results don’t look great for Mark. Finally, TechCrunch ge…

1
Tesla vs. Mark Rober, Google’s $32B M&A Bet, & XRP’s SEC Victory | E2100 1:03:01

1M ago1:03:01

1:03:01

Today’s show: Tesla FSD drama, Google’s massive $32B cybersecurity bet, and XRP’s SEC victory. Jason, Lon, and Alex break down the internet firestorm over Mark Rober’s viral Tesla test, why Google’s Wiz acquisition could spark a new M&A wave, and what the SEC dropping its case against XRP means for crypto’s future. Timestamps: (0:00) Episode Teaser…

1
AI-Powered Coding & Space Tugboats? Inside the Future of Software & Satellites! | E2099 1:01:41

1M ago1:01:41

1:01:41

Today’s show: Alex interviews two incredible founders from the TWIST 500! First, Replit CEO Amjad Masad breaks down how AI-powered coding is changing software development and what the future of agents looks like. Then, Starfish Space co-founder Austin Link explains how they’re building a satellite towing service to extend missions and clean up orbi…

1
Self-Driving Car Myths, Klarna’s Big IPO & Netflix’s $300M Gamble | E2098 1:12:52

1M ago1:12:52

1:12:52

Today’s show: Jason, Alex, and Lon break down a wild viral test on self-driving cars— will FSD see through fog, or does LiDAR win? Plus, Klarna is finally going public… but is "buy now, pay later" still the future or just a debt trap? And Netflix drops $300M on a Russo Brothers sci-fi blockbuster—critics hate it, but audiences love it. Was it worth…

1
Europe’s Startup Future with Harry Stebbings | E2097 58:43

1M ago58:43

58:43

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1
Is Project Europe a YC Riff? Nick Denton is Back! And more! | E2096 1:00:47

1M ago1:00:47

1:00:47

Today’s show: Europe wants to keep its founders from fleeing, AI is growing at breakneck speed, and Nick Denton is back with a spicy Twitter storm—so we had to talk about it. Jason, Alex, and Lon break down Project Europe, a new $10M fund aimed at stopping the European startup brain drain. Plus, Anthropic’s revenue just jumped 40% in a single quart…

1
The Future of AI Customer Support with LiveX AI’s Jia Li | AI Basics with Google Cloud 14:03

2M ago14:03

14:03

In this episode of AI Basics, Jason sits down with Jia Li from LiveX AI to explore how human-like AI agents are changing the game for businesses. Instead of clunky bots, these AI agents engage customers in real-time, helping with onboarding, support, and even stopping them from leaving before they churn. We’ll break down how they work, why they fee…

1
Student Roy Lee Hacks Amazon, SBF's Jailhouse Chat + more! | E2095 1:00:41

2M ago1:00:41

1:00:41

Timestamps: (0:00) Roy Lee's hack and Amazon's reaction (3:03) MicroStrategy's Bitcoin strategy(4:29) Market reactions to Trump's policies(6:33) Creating value in current market conditions(8:00) South by Southwest highlights (10:19) Coda. Empower your startup with Coda’s Team plan for free—get 6 months at https://www.Coda.io/twist (12:03) The $20,0…

1
AI’s Next Leap: Hyper-Realistic Agents & Unlimited Power | E2094 48:42

2M ago48:42

48:42

Today’s show: AI is evolving at lightning speed—smarter assistants, faster models, and now, the massive energy demands that come with it. In this episode, Alex dives into two cutting-edge companies from the TWIST 500 that are shaping AI’s future in very different ways. First, Alex interviews Zap Energy, where CEO Benj Conway explains how their brea…

1
Coreweave IPO, AVRide & Digg is Back! | E2093 1:08:49

2M ago1:08:49

1:08:49

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1
AI Agents & the Future of Work with LangChain’s Harrison Chase | AI Basics with Google Cloud 19:58

2M ago19:58

19:58

In this episode: Jason sits down with Harrison Chase, CEO of LangChain, to explore how AI-powered agents are transforming the way startups operate. They discuss the shift from traditional entry-level roles to AI-driven automation, the importance of human-in-the-loop systems, and the future of AI-powered assistants in business. Harrison shares insig…

1
US Crypto Reserve Bombshell, Ramp’s $13B Climb, & more | E2092 59:00

2M ago59:00

59:00

Today’s show: Trump just floated the idea of a U.S. Crypto Reserve, suggesting a 10 bips transaction tax and naming unexpected altcoins like XRP, Solana, and Cardano. Jason and Alex break down what this means for crypto markets, regulation, and startups—plus the legal and political fallout. Is this a game-changer or just another pump-and-dump contr…

1
Board Talk Empire with GRIN's Brandon Brown, Founder Hacks & SEC Memecoin Clarity? | E2091 1:14:49

2M ago1:14:49

1:14:49

Today’s show: Jason and Alex break down the latest head-scratching SEC ruling on meme coins—did they just legalize pump-and-dumps to protect Trump’s token? Plus, they dive into why venture debt can destroy startups, the rise of AI-driven companies, and how Tesla is gearing up to challenge Waymo in the self-driving car race. Then, Brandon Brown from…

1
The Incredible Double Interview: Superhuman and Robinhood | E2090 1:38:42

2M ago1:38:42

1:38:42

Today’s show: Jason interviews Rahul Vohra, CEO and founder of Superhuman, and Vlad Tenev, CEO and co-founder of Robinhood. This is a packed episode featuring founder tips, fun stories about how Superhuman and Robinhood got their start and much more! Timestamps: (0:00) Episode teaser(2:13) Product market fit and founder journeys(3:25) Jason's inves…

1
Apple Drops $500B on AI while Google Gemini Eyes Your iOS Devices! | E2089 1:07:57

2M ago1:07:57

1:07:57

Today’s show: Jason and Lon break down the latest trends shaping AI training, the evolving job market, and the shifting landscape of social media. A tribute to Steve Jobs on what would have been his 70th birthday explores his lasting impact, Apple’s massive $500 billion AI investment, and the future of US manufacturing. The conversation dives into …

1
Castelion Hypersonic Missiles and Crunchbase’s AI Powered Predictions | E2088 55:56

2M ago55:56

55:56

This Week in Startups is brought to you by… Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist AdQuick. Visit https://adquick.com/twist and mention TWIST to get $1000 off your first campaign. T…

1
EV Truck Startup Nikola Runs Out of Juice | E2087 1:06:41

2M ago1:06:41

1:06:41

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1
Is $LIBRA the End of Memecoins? with Coffeezilla | E2086 1:10:08

2M ago1:10:08

1:10:08

In today's episode: Jason and Alex break down one of the craziest crypto stories yet—a $100M meme coin meltdown, insider trading, and Argentina’s president caught in the middle. Coffeezilla joins the show to explain how meme coins are rigged, why Dave Portnoy got a $5M refund while everyone else got wrecked, and what really went down with the Libra…

1
#20 Non-Invasive Neurostimulation for Sleep: Neurovalens CEO Jason McKeown 51:21

2M ago51:21

51:21

Free Neurotech Newsletter: https://neurotechnologynews.beehiiv.com/subscribe Key Moments: 0:00 Introduction 3:23 Initial Interest in Neuroscience/Neurotechnology 5:10 Neurovalens: Background, Timeline, Origins 7:52 Clinical Trials: Insomnia, Anxiety, Obesity, PTSD, Diabetes 8:40 Neurostimulation: Type and Target 10:40 Exploring Various Treatment Ty…

1
IPO Shakeups, NVIDIA’s Big Bets & Must-Know Founder Hacks | E2085 1:20:10

2M ago1:20:10

1:20:10

Today’s show: IPO shakeups, big AI moves, and essential founder hacks—this episode covers it all. Jason breaks down Robinhood’s 6X stock surge and his strategy for $HOOD, plus the latest on tech IPOs as Turo pulls out and SailPoint surges. We dive into AI’s open-source battle, with X.ai chasing a $10B raise and DeepSeek challenging Hugging Face. An…

1
Slow Ventures' Creators Fund and Helion Energy's Fusion Reactors | 2084 1:04:47

2M ago1:04:47

1:04:47

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1
Tech's Super Bowl, Huge Earnings Week, Lon Returns and more! | E2083 1:05:18

3M ago1:05:18

1:05:18

Today on This Week in Startups: Lon Harris is back, and we’re diving into all things Super Bowl—especially the tech takeover in this year’s commercials. We break down the biggest ad moments, from Squarespace to Uber Eats, Instacart, and even Harrison Ford’s Jeep spot. Plus, we dig into Google Trends after the ChatGPT ad, the unexpected appeal ofThe…

1
Gas Stations in Space and Carried Interest on the Chopping Block | E2082 1:02:46

3M ago1:02:46

1:02:46

This Week in Startups is brought to you by… Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain athttps://www.Squarespace.com/TWIST Atlassian. Head tohttps://www.atlassian.com/software/startups to see if you qualify for 50 free seats for 12 months. AdQuick. Visithttps://adquick.com/twist and mention TWIST to…

1
Is Palantir's Surge Just Hype | E2081 57:37

3M ago57:37

57:37

This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist *Gusto pricing shown in ad is based on pricing prior to March 2025 Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at ⁠⁠https://w⁠⁠⁠⁠ww.oracle.com/twist⁠⁠⁠ Horatio. Visit https://www.hirehorati…

1
Lovable's Anton Osika on Revolutionizing Software Development and OpenAI Drops Deep Research | E2080 1:06:52

3M ago1:06:52

1:06:52

OpenAI dropped Deep Research—hilariously, the exact same name as Google’s existing tool. Jason and Alex dive into the AI arms race, break down Lovable.dev’s insane growth to $10M ARR in weeks, and test whether AI can really replace software engineers. Plus, they analyze Trump’s latest tariff chaos and what it means for startups, global trade, and t…

1
Is OpenAI Really Worth $300B? ElevenLabs’ Series C & YC’s Funding Focus | E2079 1:13:16

3M ago1:13:16

1:13:16

Today’s show: The AI revolution is about to hit your household—Jason and Alex break down how general-purpose robots, AI-powered chicken coops, and voice clones are redefining daily life and work. They dig into OpenAI’s sky-high valuation, the surprising rise of DeepSeek’s R1 model, and why the AI cost curve is dropping at an insane pace. Plus, the …

1
Boom Supersonic's Milestones, OpenAI Ethics, and Startup Tools | E2078 1:02:33

3M ago1:02:33

1:02:33

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1
DeepSeek Rattles Markets + SailPoint's Going Public… again? | E2077 59:49

3M ago59:49

59:49

Today’s show: A $6M open-source AI model from China, DeepSeek, sends shockwaves through Wall Street, wiping billions off NVIDIA’s market cap and forcing a rethink on AI infrastructure spending. We explore the 25% surge in startup shutdowns, the lessons from leaner teams, and why some companies just couldn’t make the runway. Plus, SailPoint returns …

1
Twilio Bets Small, DeepSeek Scares & the GameOn Fraud | E2076 58:24

3M ago58:24

58:24

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1
Created By Humans | Sila’s Battery Evolution | E2075 59:03

3M ago59:03

59:03

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1
#19 Building a Non-Invasive BCI/Neurotech Startup at 23: Synaptrix Co-Founder Aryan Govil 38:04

3M ago38:04

38:04

Free Neurotech Newsletter: https://neurotechnologynews.beehiiv.com/subscribe Key Moments 0:00 Introduction 2:22 Initial Interest in Neuroscience/Neurotech 4:17 Background and Origins of Synaptrix 6:15 Development of Neuralis Product 7:10 Benefits of Building a Product “In-House” 8:54 In-House Lab Build Out 10:41 Moving Quickly Through Regulatory St…

1
Trump, Memecoins, and What to Expect from the New Administration | E2074 1:12:25

3M ago1:12:25

1:12:25

Today’s show: Jason and Alex explore America's fascination with billionaires and self-made figures, touching on recent events in Washington, DC, and the tech industry's political influence. They discuss Gen X's rising political power, tech CEOs' prominence at inaugurations, and critique Democrats' tech policies. The conversation covers economic fac…

Podcasts Worth a Listen

Jason Calacanis Podcasts

Podcasts Worth a Listen