Imagine a tiny patch that could painlessly deliver life-saving vaccines without a trained medical professional. Or a malaria vaccine that doesn’t require refrigeration, making it easier to distribute in tropical countries where the disease is commonly transmitted. Those innovations, among others, are on the cusp of transforming vaccine development and delivery, a top priority in global health.

This episode of the Princeton Pulse Podcast concludes a two-part series on vaccines, which protect hundreds of millions of people from preventable illnesses like smallpox, polio, and measles. The last show addressed concerning shifts in U.S. vaccine policy. This one focuses on progress and promise, even in the face of dwindling global health resources and a host of other challenges.

Host Heather Howard, a professor at Princeton University and former New Jersey Commissioner of Health and Senior Services, is joined by two guests: Princeton Professor Andrea Graham, an evolutionary ecologist with strong research interests in immunity, disease ecology, and disease transmission; and Janeen Madan Keller, deputy director of global health policy and policy fellow at the Center for Global Development. Together, they highlight scientific discoveries that set the stage for a new generation of vaccines that could boost immunization rates around the world while preparing us for the next pandemic.

The panel shares exciting advances in the lab, from mRNA technology that can train the immune system to recognize, remember, and target invading pathogens, to plant-based edible vaccines. They also talk about overcoming barriers to access with solar-powered refrigerators that don’t depend on unreliable energy sources, combination vaccines that reduce the number of injections and medical visits, and other potential game changers that could ensure vaccines reach the people who need them most.

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Learn more about the Center for Global Development and its Tough Times, Tough Choices series.

Visit Andrea Graham’s website to read about her lab’s research on the immune system and disease transmission.

Listen to Alarming Trends in U.S. Vaccine Policy – And What We Can Do About It

The Princeton Pulse Podcast is a production of Princeton University's Center for Health and Wellbeing (CHW). The show is hosted by Heather Howard, a professor at Princeton University and former New Jersey Commissioner of Health and Senior Services, produced by Aimee Bronfeld, and edited by Alex Brownstein. You can subscribe to The Princeton Pulse Podcast on Apple Podcasts, Spotify, or wherever you enjoy your favorite podcasts.