Abstract: As artificial intelligence transforms work through automation, a "wellbeing paradox" may emerge if its social and psychological impacts are not consciously managed. This practitioner-focused research brief explores the tensions between AI's productivity gains and potential threats to human thriving. Through a review of recent studies at the intersection of technology, jobs and wellbeing, it identifies challenges like job insecurity, social isolation, technostress, employee surveillance and over-reliance on algorithms that could undermine individuals' sense of purpose, autonomy, relationships and overall wellbeing. Meanwhile, AI provides an opportunity to cultivate resilience for workers through career support, meaningful reskilling, internal mobility and social connection in the workplace. The brief also outlines strategies for organizations to optimize human-AI collaboration through transparency, explainability and prioritizing augmentation over automation. It concludes with a "digital ergonomics" framework of boundary-setting, mindfulness, presence and wellbeing nudges to proactively design technology that enhances rather than depletes human capacities and fulfillment.