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Health Longevity Secrets « »
Lasers vs Painkillers: Deep-dive into Photobiomodulation

8d ago 40:52

MP3•Episode home

Guest: Forrest Smith — serial founder bringing clinic-grade photobiomodulation to a safe, wearable form factor.
Theme: Why dose and delivery matter more than raw wattage for red light therapy.

Key takeaways

Wavelengths that work: Deep red 660 nm (blood flow, NO release, shallow penetration) + 808 nm near-IR (deeper tissues/joints).
Mechanisms: Hemoglobin photodissociates NO → vasodilation + better O₂ delivery; mitochondria’s cytochrome c oxidase bottleneck relieved → higher ATP output; downstream: resilience to oxidative stress.
Performance & recovery: Overnight reductions in CK and CRP let athletes train sooner; UFC PI and USA Weightlifting use cases mentioned.
Brains & microvessels: Near-IR protocols tied to BDNF and microvascular improvements—an emerging Alzheimer’s angle.
Dosing > device hype: Class-1 lasers allow precise, reproducible dosing to deeper targets; panels/LEDs spread light too broadly and shift dose by distance (inverse-square).
Safety & contraindications: Class-1 lasers are eye-safe in normal use; titanium implants OK (osseointegration may improve). Pregnancy and active cancer: regulatory contraindications despite encouraging early data.
Personal protocol (example): 15 min over carotids + 15 min lower abdomen (gut) upon waking; higher-melanin skin generally needs longer time at same power.

Resources & links (from interview)

Kineon: kineon.io

Chapter markers (approx.)

00:00 Why red light now?
00:34 Mission: measurable QoL at scale
03:02 Risks of NSAIDs vs alternatives
03:34 660 nm + 808 nm explained
05:34 Newer NIR bands (905–1064 nm)
07:39 Penetration depth: red vs NIR
08:34 Photoacceptors & evolution (melanin)
10:28 Hemoglobin, NO, and O₂ delivery
12:02 Mitochondria & ATP bottleneck
14:06 Brain protection & TBI athletes
14:34 CK/CRP drops & faster training
15:55 Dosing by melanin level
17:49 Implants, pregnancy, cancer notes
21:22 Biphasic dose curve; laser classes
25:26 LEDs vs lasers; panels’ dose drift
27:50 Strongest evidence areas (wound, knee OA)
29:33 Gut–brain, BDNF, microvasc/Alzheimer’s
31:46 Forrest’s daily protocol (neck + gut)
34:00 Systemic effects; fertil

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Chapters

1. Introduction to Red Light Therapy (00:00:00)

2. How Red Light Affects Our Bodies (00:05:40)

3. Wavelengths and Tissue Penetration (00:08:40)

4. Photoacceptors and Mitochondrial Effects (00:15:10)

5. Dosing, Safety and Contraindications (00:21:30)

6. LEDs vs Lasers: Key Differences (00:25:40)

7. Exciting Applications and Research Findings (00:30:50)

8. Personal Benefits and Final Thoughts (00:36:40)

223 episodes

#Fitness #Alternative Health #Medicine #Nutrition #Robert Lufkin MD #Health and Well-Being #Longevity #Rapamycin #Metabolism #Inflammation

Lasers vs Painkillers: Deep-dive into Photobiomodulation

Health Longevity Secrets

24 subscribers

published 8d ago

MP3•Episode home

Key takeaways

Wavelengths that work: Deep red 660 nm (blood flow, NO release, shallow penetration) + 808 nm near-IR (deeper tissues/joints).
Mechanisms: Hemoglobin photodissociates NO → vasodilation + better O₂ delivery; mitochondria’s cytochrome c oxidase bottleneck relieved → higher ATP output; downstream: resilience to oxidative stress.
Performance & recovery: Overnight reductions in CK and CRP let athletes train sooner; UFC PI and USA Weightlifting use cases mentioned.
Brains & microvessels: Near-IR protocols tied to BDNF and microvascular improvements—an emerging Alzheimer’s angle.
Dosing > device hype: Class-1 lasers allow precise, reproducible dosing to deeper targets; panels/LEDs spread light too broadly and shift dose by distance (inverse-square).
Safety & contraindications: Class-1 lasers are eye-safe in normal use; titanium implants OK (osseointegration may improve). Pregnancy and active cancer: regulatory contraindications despite encouraging early data.
Personal protocol (example): 15 min over carotids + 15 min lower abdomen (gut) upon waking; higher-melanin skin generally needs longer time at same power.

Resources & links (from interview)

Kineon: kineon.io

Chapter markers (approx.)

Chapters

1. Introduction to Red Light Therapy (00:00:00)

2. How Red Light Affects Our Bodies (00:05:40)

3. Wavelengths and Tissue Penetration (00:08:40)

4. Photoacceptors and Mitochondrial Effects (00:15:10)

5. Dosing, Safety and Contraindications (00:21:30)

6. LEDs vs Lasers: Key Differences (00:25:40)

7. Exciting Applications and Research Findings (00:30:50)

8. Personal Benefits and Final Thoughts (00:36:40)

223 episodes

#Fitness #Alternative Health #Medicine #Nutrition #Robert Lufkin MD #Health and Well-Being #Longevity #Rapamycin #Metabolism #Inflammation

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Health Longevity Secrets « » Lasers vs Painkillers: Deep-dive into Photobiomodulation

Chapter markers (approx.)

Chapters

1. Introduction to Red Light Therapy (00:00:00)

2. How Red Light Affects Our Bodies (00:05:40)

3. Wavelengths and Tissue Penetration (00:08:40)

4. Photoacceptors and Mitochondrial Effects (00:15:10)

5. Dosing, Safety and Contraindications (00:21:30)

6. LEDs vs Lasers: Key Differences (00:25:40)

7. Exciting Applications and Research Findings (00:30:50)

8. Personal Benefits and Final Thoughts (00:36:40)

Lasers vs Painkillers: Deep-dive into Photobiomodulation

Chapter markers (approx.)

Chapters

1. Introduction to Red Light Therapy (00:00:00)

2. How Red Light Affects Our Bodies (00:05:40)

3. Wavelengths and Tissue Penetration (00:08:40)

4. Photoacceptors and Mitochondrial Effects (00:15:10)

5. Dosing, Safety and Contraindications (00:21:30)

6. LEDs vs Lasers: Key Differences (00:25:40)

7. Exciting Applications and Research Findings (00:30:50)

8. Personal Benefits and Final Thoughts (00:36:40)

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Welcome to Player FM!

Similar to Health Longevity Secrets

Health Longevity Secrets « »
Lasers vs Painkillers: Deep-dive into Photobiomodulation