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A Cheaper Way to Make Drugs?

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Manage episode 470148847 series 3382623
Content provided by Harvard University and Harvard Graduate School of Arts. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Harvard University and Harvard Graduate School of Arts or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

The cost of prescription drugs is high—particularly in the US where consumers pay nearly three times more than those in 33 other nations in the Organization for Economic Cooperation and Development.

One factor in prices is fluorination, which plays a crucial role in the production of many widely-used pharmaceuticals. Driven by the high cost of reagents needed for the trifluoromethyl (CF₃) group, the process is expensive—and hard on the natural environment. If there was a way to make fluorination more accessible, sustainable, and affordable—it could reshape how we approach drug synthesis—and much else in chemistry.

Chemist and Harvard Griffin GSAS PhD candidate Brandon Campbell has developed an innovative method of fluorination that could do just that. Using silver and visible light, Campbell’s pioneering approach promises a cost-effective and eco-friendly alternative to traditional synthetic methods.

  continue reading

56 episodes

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A Cheaper Way to Make Drugs?

Colloquy

20 subscribers

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Manage episode 470148847 series 3382623
Content provided by Harvard University and Harvard Graduate School of Arts. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Harvard University and Harvard Graduate School of Arts or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

The cost of prescription drugs is high—particularly in the US where consumers pay nearly three times more than those in 33 other nations in the Organization for Economic Cooperation and Development.

One factor in prices is fluorination, which plays a crucial role in the production of many widely-used pharmaceuticals. Driven by the high cost of reagents needed for the trifluoromethyl (CF₃) group, the process is expensive—and hard on the natural environment. If there was a way to make fluorination more accessible, sustainable, and affordable—it could reshape how we approach drug synthesis—and much else in chemistry.

Chemist and Harvard Griffin GSAS PhD candidate Brandon Campbell has developed an innovative method of fluorination that could do just that. Using silver and visible light, Campbell’s pioneering approach promises a cost-effective and eco-friendly alternative to traditional synthetic methods.

  continue reading

56 episodes

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