Beyond the Surface: Rethinking Fish Wound Care with Naltrexone

Veterinary Vertex

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We take a fascinating dive into aquatic medicine as Drs. Anthony Cerreta and Karisa Tang share groundbreaking findings on fish wound healing. Their study reveals that topical naltrexone in iLEX ointment significantly accelerates cutaneous wound healing in black belt cichlids—a discovery with profound implications for aquatic veterinary care.
Anthony and Karisa explain how fish wounds present unique challenges due to the constant exposure to water-borne pathogens, making effective treatments critically important yet notoriously difficult to develop. What makes their findings particularly remarkable is the simplicity of the approach: applying naltrexone ointment just once every 3-4 days produced visible healing by day 19, much faster than untreated wounds. Even more surprising was how effective the treatment proved despite minimal contact time with the wounds—challenging conventional wisdom about topical treatments in aquatic animals.
This work builds on previous clinical observations at major aquariums where naltrexone showed promise treating head and lateral line erosion (HLLE). Anthony and Karisa meticulously designed their study to provide the aquatic veterinary community with solid evidence of naltrexone's efficacy. They're now expanding their research to chronic wounds across various species, potentially revolutionizing treatment protocols for fish in both professional and home aquarium settings. Their message to veterinarians and aquarists alike is refreshingly practical: this treatment is inexpensive, easy to apply, and remarkably effective despite the aquatic environment—making it a valuable addition to the limited toolkit available for fish wound management.
Have you encountered challenging wound healing cases in your aquatic patients? Try incorporating this evidence-based approach and share your experiences with the growing community of aquatic veterinary practitioners.

AJVR article: https://doi.org/10.2460/ajvr.24.04.0099

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Chapters

1. Introduction to Fish Wound Healing (00:00:00)

2. Naltrexone's Effect on Cichlid Wounds (00:02:08)

3. Origins of Fish Naltrexone Research (00:04:15)

4. Surprising Healing Speed Results (00:05:49)

5. Study Design and AI Applications (00:08:38)

6. Clinical Applications for Veterinarians (00:09:40)

151 episodes

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