AI agents could make up a significant part of company org charts within the next five years, supercharging human productivity. This week, we look at the roles, org structures, and leadership approaches needed to drive these teams forward. Featuring: Chief Content Officer Matt Davis and Chief Research Officer Kevin O’Marah.

Unpacking Microsoft’s 2025 Work Trend Index and the coming agent shake-up (01:00)

Moderna’s fusion of HR and IT (02:30)

Supply chain hiring trends for agentic AI (4:10)

“The Path to 40” and bot boss leadership (07:43)

Amazon’s two-pizza teams, Spotify guilds, and other models for functional organization (10:34)

Moving forward with imperfect data (14:40)

Teaching ethics to AI teammates… (18:32)

… and readying human employees to work with them (20:30)