Weekly: Gene-editing to make superhumans; first bird flu death in the US; perfect pasta with physics

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Episode 284

Creating disease-resistant humans may before too long be a reality thanks to advancements in CRISPR gene editing. It’s now possible to make dozens - if not hundreds - of edits to different genes at once. As the field progresses rapidly, a controversial paper published in Nature explores just how powerful this technology could be in protecting against diseases like Alzheimer’s and diabetes. But how safe is gene-editing? The paper has been criticised amid safety and ethical concerns, as well as the danger this could give rise to eugenics and designer babies.

A person in Louisiana has died from bird flu, the first known death related to the H5N1 virus in the United States. Alarms are now being raised that bird flu could mutate and lead to another covid-like pandemic. The virus has evolved to infect many species of mammals, most recently dairy cows. But given we’ve been aware of this disease for decades and have stockpiled vaccines, what are the real concerns here? Hear from experts Meghan Davis and Andy Pekosz from Johns Hopkins University.

Italian physicists have been working on an extremely important question related to…pasta. While working in Germany, Ivan Di Terlizzi and Giacomo Bartolucci became frustrated that they couldn’t perfectly recreate one of their favourite pasta meals - cacio e pepe. Thankfully, using their knowledge of phase behaviour, they figured out what was going on…in incredible detail. And bizarrely they suggest the finding may have implications for our understanding of the origins of life.

Hosts Rowan Hooper and Penny Sarchet discuss with guests Michael Le Page and Grace Wade.

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