In this interview, I talk to Prof Klaus With, the man trying to create the world's first approved medication for ME/CFS & Long Covid (Mitodicure).
🧠 This 45-minute deep dive explores the groundbreaking research that led to the current development efforts of Mitodicure and Prof. Wirth’s unifying model of ME/CFS — created in collaboration with Prof. Carmen Scheibenbogen.
We cover:
🔹 How Mitodicure is designed to heal the illness and not just suppress symptoms
🔹 Why it could significantly raise the PEM/crash threshold, improving quality of life but also allowing much deeper healing to occur (as PEM heightens and intensifies the illness)
🔹 What a patient might actually feel when taking the drug
🔹 Why drug-development-style research is vital to accelerate our understanding of ME/CFS pathophysiology
🔹 How the mystery of low blood volume in ME/CFS can be explained
🔹 How the Wirth and Scheibenbogen model accounts for muscle fibre necrosis during PEM
This may be one of the most hopeful developments the ME/CFS and Long Covid communities have seen in years.
🙏 Please watch, share widely, and help raise awareness.
The more visibility Mitodicure receives, the greater the chance of attracting investors for clinical trials — and, potentially, the possible breakthrough millions have been waiting for.

To keep up to date with Prof Wirth's work, follow the Mitodicure website: www.mitodicure.com

More about your host, Patrick Ussher

For my personal website, writings/talks, YouTube channel, Understanding ME/CFS book, social media, etc, please follow this link: https://linktr.ee/patrickussher

#MECFS #CureLongCovid #CureMECFS #Research #Medication #Mitodicure

Intro music: The Path (piano & strings) by Patrick Ussher

**Disclaimer - you should not rely on any medical information contained in this Podcast and related materials in making medical, health-related or other decisions. Please consult a doctor or other health professional**