How many organs could you donate and remain alive? How many planet Earths could fit inside the Sun? How high is a giraffe's blood pressure? Why is the sea blue? To find out, Ask The Naked Scientists!
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EP 214: Innovating large-scale and sustainable genomics with Slavé Petrovski of AstraZeneca
Manage episode 520351928 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Summary:
This week on The Genetics Podcast, Patrick is joined by Slavé Petrovski, Vice President of the Center for Genomics Research at AstraZeneca. They discuss how AstraZeneca is scaling population genomics through massive biobank collaborations, developing AI models for early disease prediction, and pioneering sustainable “green” algorithms to reduce the environmental footprint of large-scale genomic research.
Show Notes:
0:00 Intro to The Genetics Podcast
00:59 Welcome to Slavé
02:09 Slavé’s career path from business information systems to genomics
04:33 How Slavé decided to move from academia to industry
07:52 Scaling and diversifying biobank partnerships to unlock new genetic insights
12:29 Translating biobank data into predictive and preventive medicine
15:14 Discovering protective genetic variants through global biobank studies
19:13 Leveraging population genetics to identify and validate protective drug targets
23:52 Developing an AI tool (MILTON) for integrating multi-omic and clinical data for early disease prediction
28:12 Redefining clinical trials in a presymptomatic and predictive medicine era
30:49 AstraZeneca’s efforts to make large-scale genomics computing sustainable through green algorithm innovation
39:05 AstraZeneca’s open science strategy and global impact of its shared genomics tools
42:10 Fostering critical thinking and avoiding groupthink in large-scale genomics research
45:30 Looking ahead to the next decade of genomics and precision healthcare
50:01 Closing remarks
Find out more
MILTON (https://www.astrazeneca.com/r-d/our-technologies/machine-learning-drug-discovery.html)
PheWAS Portal (https://azphewas.com/)
Upcoming webcast with deep dive into MILTON & PheWAS (https://www.nature.com/articles/d44224-025-00033-7)
Please consider rating and reviewing us on your chosen podcast listening platform!
https://drive.google.com/file/d/1Bp2_wVNSzntTs_zuoizU8bX1dvao4jfj/view?usp=share_link
217 episodes
Share
Manage episode 520351928 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Summary:
This week on The Genetics Podcast, Patrick is joined by Slavé Petrovski, Vice President of the Center for Genomics Research at AstraZeneca. They discuss how AstraZeneca is scaling population genomics through massive biobank collaborations, developing AI models for early disease prediction, and pioneering sustainable “green” algorithms to reduce the environmental footprint of large-scale genomic research.
Show Notes:
0:00 Intro to The Genetics Podcast
00:59 Welcome to Slavé
02:09 Slavé’s career path from business information systems to genomics
04:33 How Slavé decided to move from academia to industry
07:52 Scaling and diversifying biobank partnerships to unlock new genetic insights
12:29 Translating biobank data into predictive and preventive medicine
15:14 Discovering protective genetic variants through global biobank studies
19:13 Leveraging population genetics to identify and validate protective drug targets
23:52 Developing an AI tool (MILTON) for integrating multi-omic and clinical data for early disease prediction
28:12 Redefining clinical trials in a presymptomatic and predictive medicine era
30:49 AstraZeneca’s efforts to make large-scale genomics computing sustainable through green algorithm innovation
39:05 AstraZeneca’s open science strategy and global impact of its shared genomics tools
42:10 Fostering critical thinking and avoiding groupthink in large-scale genomics research
45:30 Looking ahead to the next decade of genomics and precision healthcare
50:01 Closing remarks
Find out more
MILTON (https://www.astrazeneca.com/r-d/our-technologies/machine-learning-drug-discovery.html)
PheWAS Portal (https://azphewas.com/)
Upcoming webcast with deep dive into MILTON & PheWAS (https://www.nature.com/articles/d44224-025-00033-7)
Please consider rating and reviewing us on your chosen podcast listening platform!
https://drive.google.com/file/d/1Bp2_wVNSzntTs_zuoizU8bX1dvao4jfj/view?usp=share_link
217 episodes
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Similar to The Genetics Podcast
How many organs could you donate and remain alive? How many planet Earths could fit inside the Sun? How high is a giraffe's blood pressure? Why is the sea blue? To find out, Ask The Naked Scientists!
…
continue reading
A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vineeta Agarwala, Julie Yoo, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg Verdine, Fei-Fei Li, and Suchi Saria, as they explore the i ...
…
continue reading
Whether the topic is popcorn or particle physics, you can count on BrainStuff to explore -- and explain -- the everyday science in the world around us.
…
continue reading
I discuss a variety of topics in both the natural and social sciences, exploring the many fascinating insights that the scientific method yields about the world around us.
…
continue reading
The Science Show gives Australians unique insights into the latest scientific research and debate, from the physics of cricket to prime ministerial biorhythms.
…
continue reading
The kickass science and technology radio show that delivers an irreverent look at the week in science and technology.
…
continue reading
When you hear the words Alzheimer's disease, what do you think of? The truth is, the picture most of us have of the disease is incomplete. Alzheimer's disease doesn't start when someone starts to lose their memory. It actually starts years – sometimes decades – earlier. The Rethinking Alzheimer's Disease Podcast is an engaging, narrative-style podcast miniseries for those curious or motivated to learn about Alzheimer’s disease. Perhaps you have a family member with Alzheimer’s disease, or ca ...
…
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We take a critter’s eye view to explore how animal behavior parallels humans. Join comedians and science-lovers as we get inside the minds of animals
…
continue reading
DNA science. Artificial intelligence. Smartphones and 3D printers. Science and technology have transformed the world we live in. But how did we get here? It wasn’t by accident. Well, sometimes it was. It was also the result of hard work, teamwork, and competition. And incredibly surprising moments. Hosted by bestselling author Steven Johnson (“How We Got To Now”), American Innovations uses immersive scenes to tell the stories of the scientists, engineers, and ordinary people behind the great ...
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…
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