Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Similar to The Genetics Podcast
Whether the topic is popcorn or particle physics, you can count on BrainStuff to explore -- and explain -- the everyday science in the world around us.
…
continue reading
We take a critter’s eye view to explore how animal behavior parallels humans. Join comedians and science-lovers as we get inside the minds of animals
…
continue reading
The Science Show gives Australians unique insights into the latest scientific research and debate, from the physics of cricket to prime ministerial biorhythms.
…
continue reading
The kickass science and technology radio show that delivers an irreverent look at the week in science and technology.
…
continue reading
DNA science. Artificial intelligence. Smartphones and 3D printers. Science and technology have transformed the world we live in. But how did we get here? It wasn’t by accident. Well, sometimes it was. It was also the result of hard work, teamwork, and competition. And incredibly surprising moments. Hosted by bestselling author Steven Johnson (“How We Got To Now”), American Innovations uses immersive scenes to tell the stories of the scientists, engineers, and ordinary people behind the great ...
…
continue reading
Come dive into one of the curiously delightful conversations overheard at National Geographic’s headquarters, as we follow explorers, photographers, and scientists to the edges of our big, weird, beautiful world. Hosted by Peter Gwin and Amy Briggs.
…
continue reading
1
Real Ghost Stories Online
Real Ghost Stories Online | Paranormal, Supernatural & Horror Radio
2k
7k
Get ready to have your spine tingling and your hairs standing on end with the Daily Paranormal Podcast hosted by Tony Brueski. This show is no joke - it's packed with real-life horror stories of ghosts, demons, haunted houses, possessions, shadow people, and all things supernatural that will leave you quivering with fear. Our listeners can't get enough of our bone-chilling tales, describing them as the "best ghost story podcast out there." Don't expect the same old cliché zombies, vampires, ...
…
continue reading
Help me fill in the blanks of the practice of ED Critical Care. In this podcast, we discuss all things related to the crashing, critically ill patient in the Emergency Department. Find the show notes at emcrit.org.
…
continue reading
Interviews with Anthropologists about their New Books Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/anthropology
…
continue reading
Player FM - Podcast App
Go offline with the Player FM app!
Go offline with the Player FM app!
))
EP 196: A new vision for sequencing: In-sample multiomics and precision medicine with Molly He
Manage episode 494936219 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
This week on The Genetics Podcast, Patrick is joined by Molly He, CEO and co-founder of Element Biosciences. They discuss the current landscape of sequencing technologies, Element’s innovative sequencing platform, and the potential of using in-sample multiomic profiling across different stages of drug discovery.
Show Notes:
0:00 Intro to The Genetics Podcast
00:59 Welcome to Molly
01:42 Persistent barriers in precision medicine
04:54 Limitations of multiomics technologies and the unique advantage of Element’s approach
07:33 How Element started by inventing an ambitious sequencing instrument
11:33 Overview of the chemistry behind Element’s sequencing technology
14:41 Sequencing workflow of Element’s technology and technical advantages
18:24 Sequencing inside cells and drug discovery insights from a study on tyrosine kinase inhibitor (TKI) resistance pathways
25:57 Sequencing for CRISPR perturbation and direct genotype–phenotype linkage in the same cell
27:33 Whole-transcriptome in situ sequencing and applications in patient samples
29:19 Simplifying single-cell transcriptomics with direct in-sample sequencing
30:31 Applying the single-cell spatial technology to different steps of the drug discovery process
36:43 Competition in the sequencing industry and recent news about Illumina filing a patent infringement case against Element
38:43 Lessons from building Element over eight years
40:32 Insight into maintaining a cohesive culture as Element has multiplied in size and across countries
42:06 The importance of input data quality for AI applications and excitement about the possibility of predicting biology
45:40 Closing remarks
Find out more
Element Biosciences (https://www.elementbiosciences.com/)
Pre-print (https://www.biorxiv.org/content/10.1101/2025.05.06.652479v1)
Please consider rating and reviewing us on your chosen podcast listening platform!
https://drive.google.com/file/d/1Bp2_wVNSzntTs_zuoizU8bX1dvao4jfj/view?usp=share_link
206 episodes
Share
Manage episode 494936219 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
This week on The Genetics Podcast, Patrick is joined by Molly He, CEO and co-founder of Element Biosciences. They discuss the current landscape of sequencing technologies, Element’s innovative sequencing platform, and the potential of using in-sample multiomic profiling across different stages of drug discovery.
Show Notes:
0:00 Intro to The Genetics Podcast
00:59 Welcome to Molly
01:42 Persistent barriers in precision medicine
04:54 Limitations of multiomics technologies and the unique advantage of Element’s approach
07:33 How Element started by inventing an ambitious sequencing instrument
11:33 Overview of the chemistry behind Element’s sequencing technology
14:41 Sequencing workflow of Element’s technology and technical advantages
18:24 Sequencing inside cells and drug discovery insights from a study on tyrosine kinase inhibitor (TKI) resistance pathways
25:57 Sequencing for CRISPR perturbation and direct genotype–phenotype linkage in the same cell
27:33 Whole-transcriptome in situ sequencing and applications in patient samples
29:19 Simplifying single-cell transcriptomics with direct in-sample sequencing
30:31 Applying the single-cell spatial technology to different steps of the drug discovery process
36:43 Competition in the sequencing industry and recent news about Illumina filing a patent infringement case against Element
38:43 Lessons from building Element over eight years
40:32 Insight into maintaining a cohesive culture as Element has multiplied in size and across countries
42:06 The importance of input data quality for AI applications and excitement about the possibility of predicting biology
45:40 Closing remarks
Find out more
Element Biosciences (https://www.elementbiosciences.com/)
Pre-print (https://www.biorxiv.org/content/10.1101/2025.05.06.652479v1)
Please consider rating and reviewing us on your chosen podcast listening platform!
https://drive.google.com/file/d/1Bp2_wVNSzntTs_zuoizU8bX1dvao4jfj/view?usp=share_link
206 episodes
All episodes
×
Welcome to Player FM!
Player FM is scanning the web for high-quality podcasts for you to enjoy right now. It's the best podcast app and works on Android, iPhone, and the web. Signup to sync subscriptions across devices.
Similar to The Genetics Podcast
Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
Whether the topic is popcorn or particle physics, you can count on BrainStuff to explore -- and explain -- the everyday science in the world around us.
…
continue reading
We take a critter’s eye view to explore how animal behavior parallels humans. Join comedians and science-lovers as we get inside the minds of animals
…
continue reading
The Science Show gives Australians unique insights into the latest scientific research and debate, from the physics of cricket to prime ministerial biorhythms.
…
continue reading
The kickass science and technology radio show that delivers an irreverent look at the week in science and technology.
…
continue reading
DNA science. Artificial intelligence. Smartphones and 3D printers. Science and technology have transformed the world we live in. But how did we get here? It wasn’t by accident. Well, sometimes it was. It was also the result of hard work, teamwork, and competition. And incredibly surprising moments. Hosted by bestselling author Steven Johnson (“How We Got To Now”), American Innovations uses immersive scenes to tell the stories of the scientists, engineers, and ordinary people behind the great ...
…
continue reading
Come dive into one of the curiously delightful conversations overheard at National Geographic’s headquarters, as we follow explorers, photographers, and scientists to the edges of our big, weird, beautiful world. Hosted by Peter Gwin and Amy Briggs.
…
continue reading
1
Real Ghost Stories Online
Real Ghost Stories Online | Paranormal, Supernatural & Horror Radio
2k7k
Get ready to have your spine tingling and your hairs standing on end with the Daily Paranormal Podcast hosted by Tony Brueski. This show is no joke - it's packed with real-life horror stories of ghosts, demons, haunted houses, possessions, shadow people, and all things supernatural that will leave you quivering with fear. Our listeners can't get enough of our bone-chilling tales, describing them as the "best ghost story podcast out there." Don't expect the same old cliché zombies, vampires, ...
…
continue reading
Help me fill in the blanks of the practice of ED Critical Care. In this podcast, we discuss all things related to the crashing, critically ill patient in the Emergency Department. Find the show notes at emcrit.org.
…
continue reading
Interviews with Anthropologists about their New Books Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/anthropology
…
continue reading
Player FM - Podcast App
Go offline with the Player FM app!
Go offline with the Player FM app!
