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EP 189: From genetic heritability in twins to gut health with Tim Spector of King’s College London and Zoe

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Manage episode 485597242 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

Summary:

This week on The Genetics Podcast, Patrick is joined by Tim Spector, Professor of Genetic Epidemiology at King’s College London and co-founder of Zoe. They discuss surprising insights on heritability from decades of twin research, the profound impact of the microbiome on health and disease, and the effect of diet on the gut microbiome.

Show Notes:

0:00 Intro to The Genetics Podcast

00:58 Welcome to Tim and his journey from clinical medicine to pioneering twin studies and uncovering the heritability of diseases and traits

07:20 Exploring missing heritability and why twin studies and GWAS offer different answers

10:37 What a global mega twin registry could reveal about epigenetics, environment, and disease

13:40 Findings from a twin microbiome study and how that evolved into a new chapter in Tim’s research career

16:50 The profound impact of the microbiome on health

21:08 Evolution in microbiome research techniques, microbe-diet associations, and the need for longitudinal studies

27:00 Potential reasons why fecal transplant did not turn out to be as effective as predicted

28:53 The importance of balance in the gut microbiome and how it can be involved in cancer and the drug response

35:54 Barriers to translating microbiome science into healthcare

38:38 The impact of microplastics and ultra-processed foods on the microbiome

41:27 Moving away from diversity measures for evaluating the microbiome and towards a more comprehensive score metric

44:36 Closing remarks with information on Tim’s upcoming book as well as Zoe products and app

Find out more

Please consider rating and reviewing us on your chosen podcast listening platform!

https://drive.google.com/file/d/1Bp2_wVNSzntTs_zuoizU8bX1dvao4jfj/view?usp=share_link

  continue reading

218 episodes

Artwork
iconShare
 
Manage episode 485597242 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

Summary:

This week on The Genetics Podcast, Patrick is joined by Tim Spector, Professor of Genetic Epidemiology at King’s College London and co-founder of Zoe. They discuss surprising insights on heritability from decades of twin research, the profound impact of the microbiome on health and disease, and the effect of diet on the gut microbiome.

Show Notes:

0:00 Intro to The Genetics Podcast

00:58 Welcome to Tim and his journey from clinical medicine to pioneering twin studies and uncovering the heritability of diseases and traits

07:20 Exploring missing heritability and why twin studies and GWAS offer different answers

10:37 What a global mega twin registry could reveal about epigenetics, environment, and disease

13:40 Findings from a twin microbiome study and how that evolved into a new chapter in Tim’s research career

16:50 The profound impact of the microbiome on health

21:08 Evolution in microbiome research techniques, microbe-diet associations, and the need for longitudinal studies

27:00 Potential reasons why fecal transplant did not turn out to be as effective as predicted

28:53 The importance of balance in the gut microbiome and how it can be involved in cancer and the drug response

35:54 Barriers to translating microbiome science into healthcare

38:38 The impact of microplastics and ultra-processed foods on the microbiome

41:27 Moving away from diversity measures for evaluating the microbiome and towards a more comprehensive score metric

44:36 Closing remarks with information on Tim’s upcoming book as well as Zoe products and app

Find out more

Please consider rating and reviewing us on your chosen podcast listening platform!

https://drive.google.com/file/d/1Bp2_wVNSzntTs_zuoizU8bX1dvao4jfj/view?usp=share_link

  continue reading

218 episodes

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