In this comprehensive discussion, Dr. Claire Merrifield delves into the intricacies of the endocrine system, explaining the structure and function of various glands and hormones. The conversation touches on the hormone production process, the interplay between the endocrine and nervous systems, and the impact of hormones on bodily functions. Key topics include thyroid health, cortisol levels, the role of stress, and hormone replacement therapies for both men and women. Dr. Merrifield also sheds light on common misconceptions related to hormonal health, emphasizing the importance of managing stress and maintaining a balanced lifestyle for overall well-being.

Dr Claire Merrifield MBBS MRCGP PhD | Co-Founder & Medical Director, Selph Claire is a GP, microbiome researcher and trained mindfulness instructor who brings a rare blend of clinical experience, scientific expertise and real-world empathy to modern healthcare. She’s the Medical Director of Selph, and the heart of its mission: to help people take back control of their own health, with guidance that’s holistic, practical and grounded in science. Claire completed her medical training at Imperial College London, where she later undertook a PhD exploring the link between gut microbes and the immune system. Her research has focused on probiotics, nutrition, immunology and the prevention of chronic illness. As a GP, Claire has supported thousands of patients in understanding their bodies, navigating the healthcare system and making sustainable lifestyle changes — especially women’s health, burnout, and gut-brain connection. Claire is also a certified Breathworks Mindfulness instructor, adding depth and compassion to her clinical approach. With her unique ability to bridge science and everyday life, Claire is on a mission to make proactive healthcare more accessible, inclusive and empowering.

Dr. Merrifield's Links:

www.selph.co.uk

https://www.linkedin.com/in/clairemerrifield/

https://www.instagram.com/selphhealthuk/

[email protected]

Learn More about Dr. Darian:

Website: https://doctordarianparker.com/

LinkedIn: https://www.linkedin.com/in/darianparker/

Dr. Darian's Affiliates:

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Chapters:

00:00 Introduction to the Endocrine System

00:54 Hormones and Their Functions

03:15 Brain's Role in Hormone Production

05:31 Thyroid and Parathyroid Glands

07:15 Gastrointestinal Hormones

09:47 Kidneys and Adrenal Glands

12:21 Sex Hormones and Fat's Role

15:26 Thyroid Dysfunction and Weight Loss

19:25 Optimizing Thyroid Function

24:00 Medication Resistance and Hormone Myths

28:42 Complexity of the Human Body

31:05 Exploring Endocrine System Dysfunction and Heritability

33:44 Understanding Cortisol: The Stress Hormone

37:21 The Impact of Stress on Health and Wellbeing

41:54 Inflammation and Aging: The Hidden Connection

45:27 The Importance of Self-Care and Mindfulness

52:29 Hormone Replacement Therapy: Estrogen and Testosterone