Is measuring your “biological age” really the key to living longer or just clever marketing?

In this fascinating debate, three leading voices in longevity, Dr. Matt Kaeberlein, Dr. Aubrey de Grey, and Dr. Gordan Lauc, join Julian to unpack what it really means to measure aging and whether modern “biological clocks” actually tell us anything useful to the great challenges facing longevity moving forward.

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The conversation goes beyond the hype to address the future of preventative medicine, the limits of today’s health technology, and how AI and personalized data could reshape how we measure and maintain our health. Together, they challenge the idea of “one number fits all,” arguing instead for a holistic approach that blends biomarkers, lifestyle insights, and clinical-grade precision to build a healthier, longer-lived population.

What You’ll Learn

• Why biological age is still more of an estimate than an exact science

• The critical difference between chronological age and biological function

• How glycans may become the next frontier in measuring inflammation and aging

• The major limitations and errors of popular epigenetic age tests

• Why consumer health tools can motivate but also mislead users

• How AI and personalized data could revolutionize preventative care

• The ethical and societal challenges of longevity and how fast we should really go

⏱ Timestamps

00:00 Introduction

00:39 How do you measure biological age?

04:41 The role of advanced biomarkers in health

06:28 Understanding the glycan age test

10:19 Raising awareness on glycan age and inflammation

14:26 The science behind measuring biological age

18:48 How high error rates can mislead results

22:07 Should you test your biological age?

23:21 The hidden risks of sample mix-ups

26:46 Do we really need biological age tests?

27:09 The problem with epigenetic tests and misinterpreted data

30:40 What counts as a reliable health measure?

34:51 The power of comprehensive health metrics

38:20 Building evidence-based longevity medicine

40:05 Why modern medicine is failing us

41:24 The risk of oversimplifying longevity science

46:50 Why the culture of medicine must change

51:17 The future of longevity and aging research

54:04 The unknown frontiers of longevity

58:10 How bad science misuses resources

01:01:16 When influencers take longevity too far

01:03:00 Tools that actually help us live longer

01:06:33 Taking ownership of your health

01:10:20 What the future holds for healthy aging

🎙 Hosted by Julian Issa 📸 Instagram: @thebeyondtomorrowpodcast 🌐 Website: www.beyondtomorrowpodcast.com 📩 Email: [email protected] 🎧 Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Episode Resources:

Aubrey de Grey:Linkedin: https://www.linkedin.com/in/aubrey-de-grey-24260b/

Instagram: https://www.instagram.com/aubreydegrey/ X: https://x.com/aubreydegrey

Matt Kaeberlein

LinkedIn: https://www.linkedin.com/in/mkaeberlein

X: https://x.com/mkaeberlein

Instagram: https://www.instagram.com/mkaeberlein

YouTube: https://www.youtube.com/@optispan

TikTok: https://www.tiktok.com/@optispan

Gordan Lauc

LinkedIn: https://hr.linkedin.com/in/gordanlauc

Instagram: https://www.instagram.com/gordanlauc

X: https://x.com/GordanLauc