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#72: John Rolston — Closed-Loop Stimulation, Seizure Dynamics, and the New Frontiers of Epilepsy Treatment

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Manage episode 497734652 series 2887135
Content provided by Andreas Horn. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Andreas Horn or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

Today, we had the privilege of speaking with Dr. John Rolston, a leading voice at the intersection of neurosurgery, epilepsy, and brain stimulation.

Dr. Rolston is an Associate Professor of Neurosurgery at Harvard Medical School and the Director of Epilepsy Surgery at Brigham and Women’s Hospital. His pioneering work bridges clinical neurosurgery and computational neuroscience, focusing on how electrical stimulation can modulate dysfunctional brain networks to treat epilepsy, movement disorders, and disorders of consciousness.

In this episode, we explored the complexities of neuromodulation—what makes stimulation effective, why patient-specific targeting matters, and how brain states influence therapeutic outcomes. Dr. Rolston also shared his lab’s work on traveling waves in the brain and how these insights are transforming seizure localization and surgical decision-making. From closed-loop stimulation to stem cell therapy for Parkinson’s disease, Dr. Rolston walks us through the evolving landscape of functional neurosurgery and its future.

  continue reading

72 episodes

Artwork
iconShare
 
Manage episode 497734652 series 2887135
Content provided by Andreas Horn. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Andreas Horn or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

Today, we had the privilege of speaking with Dr. John Rolston, a leading voice at the intersection of neurosurgery, epilepsy, and brain stimulation.

Dr. Rolston is an Associate Professor of Neurosurgery at Harvard Medical School and the Director of Epilepsy Surgery at Brigham and Women’s Hospital. His pioneering work bridges clinical neurosurgery and computational neuroscience, focusing on how electrical stimulation can modulate dysfunctional brain networks to treat epilepsy, movement disorders, and disorders of consciousness.

In this episode, we explored the complexities of neuromodulation—what makes stimulation effective, why patient-specific targeting matters, and how brain states influence therapeutic outcomes. Dr. Rolston also shared his lab’s work on traveling waves in the brain and how these insights are transforming seizure localization and surgical decision-making. From closed-loop stimulation to stem cell therapy for Parkinson’s disease, Dr. Rolston walks us through the evolving landscape of functional neurosurgery and its future.

  continue reading

72 episodes

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