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Update Course Rewind: MMP-7 & Biliary Atresia Diagnosis 2024
Manage episode 470828974 series 2973314
In this Update Course Rewind session, Dr. Greg Tiao, Surgical Director of the Liver Transplantation Program at Cincinnati Children’s, discusses the critical role of MMP-7 as a biomarker in the early diagnosis of biliary atresia. With data showing that every 10-day delay in treatment worsens outcomes by 20%, early detection is essential for improving native liver survival.
Key Highlights:
- Importance of Early Diagnosis: Performing a Kasai procedure before 45 days significantly improves patient outcomes.
- MMP-7 as a Biomarker: Validated in international studies, MMP-7 is proving to be a powerful diagnostic tool.
- Challenges in Diagnosis: Distinguishing BA from other neonatal cholestasis conditions remains complex.
- Global Impact: Lessons from high-incidence regions like China are helping shape best practices in North America.
With the integration of MMP-7 testing, pediatric surgery is moving towards earlier diagnosis and intervention, improving the chances of avoiding liver transplant in affected infants. Don’t forget to like, comment, and subscribe for more updates!
399 episodes
Manage episode 470828974 series 2973314
In this Update Course Rewind session, Dr. Greg Tiao, Surgical Director of the Liver Transplantation Program at Cincinnati Children’s, discusses the critical role of MMP-7 as a biomarker in the early diagnosis of biliary atresia. With data showing that every 10-day delay in treatment worsens outcomes by 20%, early detection is essential for improving native liver survival.
Key Highlights:
- Importance of Early Diagnosis: Performing a Kasai procedure before 45 days significantly improves patient outcomes.
- MMP-7 as a Biomarker: Validated in international studies, MMP-7 is proving to be a powerful diagnostic tool.
- Challenges in Diagnosis: Distinguishing BA from other neonatal cholestasis conditions remains complex.
- Global Impact: Lessons from high-incidence regions like China are helping shape best practices in North America.
With the integration of MMP-7 testing, pediatric surgery is moving towards earlier diagnosis and intervention, improving the chances of avoiding liver transplant in affected infants. Don’t forget to like, comment, and subscribe for more updates!
399 episodes
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