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Episode 2.2 - A transcriptional cofactor‐mediated dependency module

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Manage episode 431340554 series 3484302
Content provided by HemaSphere Journal. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by HemaSphere Journal or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

In this newest podcast episode, Dr Charles de Bock hosts Dr Thomas Mercher and Dr Alexandre Fagnan. This episode is based on their recent paper, “The ETO2 transcriptional co-factor maintains acute leukemia by driving a MYB/EP300-dependent stemness program”, highlighting ETO2 activated gene transcription and how this affects erythroleukemia. The discussion traces the journey from part of Dr Fagnan’s PhD project (2022 EHA Junior Grant awardee), the findings in the paper and what may lie beyond.

This episode is also available on our YouTube channel .

Listen and enjoy casual, insightful discussions about #hematology research.

You can find the referenced article, “The ETO2 transcriptional co-factor maintains acute leukemia by driving a MYB/EP300-dependent stemness program” in full and open access, here on the HemaSphere website.

  continue reading

22 episodes

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iconShare
 
Manage episode 431340554 series 3484302
Content provided by HemaSphere Journal. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by HemaSphere Journal or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

In this newest podcast episode, Dr Charles de Bock hosts Dr Thomas Mercher and Dr Alexandre Fagnan. This episode is based on their recent paper, “The ETO2 transcriptional co-factor maintains acute leukemia by driving a MYB/EP300-dependent stemness program”, highlighting ETO2 activated gene transcription and how this affects erythroleukemia. The discussion traces the journey from part of Dr Fagnan’s PhD project (2022 EHA Junior Grant awardee), the findings in the paper and what may lie beyond.

This episode is also available on our YouTube channel .

Listen and enjoy casual, insightful discussions about #hematology research.

You can find the referenced article, “The ETO2 transcriptional co-factor maintains acute leukemia by driving a MYB/EP300-dependent stemness program” in full and open access, here on the HemaSphere website.

  continue reading

22 episodes

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