He was born Hamish Watson, a surfie dude from Sydney – but he could morph into whatever you needed him to be. Hamish is due to be sentenced to jail in early 2019 for swindling a handful of victims out of more than $7m. But these crimes are just the final pages in a resume too thick to staple; for decades he’s duped victims in the US, Canada, Britain, Hong Kong and Australia. How did he do it? How did he evade authorities around the world for so long and what’s he done with all those tens of ...
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Developing FLEXISyn to Identify and Measure Changes in Alpha-Synuclein in Parkinson's Disease with Judith Steen
Manage episode 465468414 series 2456444
Content provided by The Michael J. Fox Foundation for Parkinson’s Research. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by The Michael J. Fox Foundation for Parkinson’s Research or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
New qualitative and quantitative tools are being developed to measure and track changes in proteins relevant for neurodegenerative disease, and these tools have the potential to accelerate drug discovery and clinical trials. In this episode, Dr. Judith Steen discusses her work creating novel qualitative and quantitative tools and workflows at the interface of proteomics and transcriptomics, including their novel FLEXI platform. This platform uses targeted, high- throughput quantitative mass spectrometry to isolate, quantify, and identify molecular changes in proteins. She describes her ongoing project, funded by The Michael J. Fox Foundation, to develop FLEXISyn, which aims to track post-translational changes in alpha-synuclein to better understand how the protein becomes dysfunctional and begins misfolding and forming toxic aggregations in Parkinson's disease. Judith is Associate Professor of Neurology at Harvard Medical School, a member of the Harvard Stem Cell Institute, and Director of the Neuroproteomics Laboratory in the F.M. Kirby Neurobiology Center at Boston Children's Hospital.
Mentioned in this episode:
This podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience. These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.
From now through December 2, you can help accelerate Parkinson’s research. This Giving Tuesday, all donations to The Michael J. Fox Foundation will be matched up to $4 million, which means your impact will be doubled. Visit michaeljfox.org/givetoresearch to be part of the cure.
256 episodes
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Manage episode 465468414 series 2456444
Content provided by The Michael J. Fox Foundation for Parkinson’s Research. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by The Michael J. Fox Foundation for Parkinson’s Research or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
New qualitative and quantitative tools are being developed to measure and track changes in proteins relevant for neurodegenerative disease, and these tools have the potential to accelerate drug discovery and clinical trials. In this episode, Dr. Judith Steen discusses her work creating novel qualitative and quantitative tools and workflows at the interface of proteomics and transcriptomics, including their novel FLEXI platform. This platform uses targeted, high- throughput quantitative mass spectrometry to isolate, quantify, and identify molecular changes in proteins. She describes her ongoing project, funded by The Michael J. Fox Foundation, to develop FLEXISyn, which aims to track post-translational changes in alpha-synuclein to better understand how the protein becomes dysfunctional and begins misfolding and forming toxic aggregations in Parkinson's disease. Judith is Associate Professor of Neurology at Harvard Medical School, a member of the Harvard Stem Cell Institute, and Director of the Neuroproteomics Laboratory in the F.M. Kirby Neurobiology Center at Boston Children's Hospital.
Mentioned in this episode:
This podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience. These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.
From now through December 2, you can help accelerate Parkinson’s research. This Giving Tuesday, all donations to The Michael J. Fox Foundation will be matched up to $4 million, which means your impact will be doubled. Visit michaeljfox.org/givetoresearch to be part of the cure.
256 episodes
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Similar to The Michael J. Fox Foundation Parkinson's Podcast
He was born Hamish Watson, a surfie dude from Sydney – but he could morph into whatever you needed him to be. Hamish is due to be sentenced to jail in early 2019 for swindling a handful of victims out of more than $7m. But these crimes are just the final pages in a resume too thick to staple; for decades he’s duped victims in the US, Canada, Britain, Hong Kong and Australia. How did he do it? How did he evade authorities around the world for so long and what’s he done with all those tens of ...
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continue reading
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…
continue reading
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…
continue reading
In the war on terror, who is it that we’re really fighting? “Caliphate” follows Rukmini Callimachi, who covers terrorism for The New York Times, on her quest to understand ISIS. For more information about the series, visit nytimes.com/caliphate. This series includes disturbing language and scenes of graphic violence. Producer: Andy Mills; Reporters: Rukmini Callimachi and Andy Mills; Managing Producer: Larissa Anderson; Editors: Wendy Dorr and Larissa Anderson; Associate Producer: Asthaa Cha ...
…
continue reading
America is divided, and it always has been. We're going back to the moment when that split turned into war. This is Uncivil: Gimlet Media's new history podcast, hosted by journalists Jack Hitt and Chenjerai Kumanyika. We ransack the official version of the Civil War, and take on the history you grew up with. We bring you untold stories about covert operations, corruption, resistance, mutiny, counterfeiting, antebellum drones, and so much more. And we connect these forgotten struggles to the ...
…
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