Help me fill in the blanks of the practice of ED Critical Care. In this podcast, we discuss all things related to the crashing, critically ill patient in the Emergency Department. Find the show notes at emcrit.org.
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Metastatic BRCA-Negative, Triple-Negative Breast Cancer — An Interview with Prof Peter Schmid on Optimal Management (Companion Faculty Lecture)
QUICKTIME•Episode home
Manage episode 507919498 series 2530615
Content provided by Dr Neil Love. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr Neil Love or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Featuring a slide presentation and related discussion from Prof Peter Schmid, including the following topics:
- Evolution of the therapeutic landscape for metastatic triple-negative breast cancer; age of immunotherapy (0:00)
- Case: A woman in her early 40s with no actionable mutations (7:29)
- Evolution of antibody-drug conjugates (ADCs) in the management of metastatic breast cancer (11:13)
- TROP2-directed ADCs (15:22)
- Case: A woman in her early 50s with PD-L1-negative, HR-negative, HER2-low de novo metastatic breast cancer (20:21)
- Novel strategies utilizing approved and investigational ADCs (23:28)
- Case: A woman in her early 60s with loss of HER2 expression on disease progression (31:39)
- ADCs in combination with immunotherapy (32:51)
751 episodes
QUICKTIME•Episode home
Manage episode 507919498 series 2530615
Content provided by Dr Neil Love. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr Neil Love or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Featuring a slide presentation and related discussion from Prof Peter Schmid, including the following topics:
- Evolution of the therapeutic landscape for metastatic triple-negative breast cancer; age of immunotherapy (0:00)
- Case: A woman in her early 40s with no actionable mutations (7:29)
- Evolution of antibody-drug conjugates (ADCs) in the management of metastatic breast cancer (11:13)
- TROP2-directed ADCs (15:22)
- Case: A woman in her early 50s with PD-L1-negative, HR-negative, HER2-low de novo metastatic breast cancer (20:21)
- Novel strategies utilizing approved and investigational ADCs (23:28)
- Case: A woman in her early 60s with loss of HER2 expression on disease progression (31:39)
- ADCs in combination with immunotherapy (32:51)
751 episodes
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