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Metastatic BRCA-Negative, Triple-Negative Breast Cancer — An Interview with Prof Peter Schmid on Optimal Management (Companion Faculty Lecture)

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Manage episode 507919498 series 2530615
Content provided by Dr Neil Love. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr Neil Love or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

Featuring a slide presentation and related discussion from Prof Peter Schmid, including the following topics:

  • Evolution of the therapeutic landscape for metastatic triple-negative breast cancer; age of immunotherapy (0:00)
  • Case: A woman in her early 40s with no actionable mutations (7:29)
  • Evolution of antibody-drug conjugates (ADCs) in the management of metastatic breast cancer (11:13)
  • TROP2-directed ADCs (15:22)
  • Case: A woman in her early 50s with PD-L1-negative, HR-negative, HER2-low de novo metastatic breast cancer (20:21)
  • Novel strategies utilizing approved and investigational ADCs (23:28)
  • Case: A woman in her early 60s with loss of HER2 expression on disease progression (31:39)
  • ADCs in combination with immunotherapy (32:51)

CME information and select publications

  continue reading

751 episodes

Artwork
iconShare
 
Manage episode 507919498 series 2530615
Content provided by Dr Neil Love. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr Neil Love or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

Featuring a slide presentation and related discussion from Prof Peter Schmid, including the following topics:

  • Evolution of the therapeutic landscape for metastatic triple-negative breast cancer; age of immunotherapy (0:00)
  • Case: A woman in her early 40s with no actionable mutations (7:29)
  • Evolution of antibody-drug conjugates (ADCs) in the management of metastatic breast cancer (11:13)
  • TROP2-directed ADCs (15:22)
  • Case: A woman in her early 50s with PD-L1-negative, HR-negative, HER2-low de novo metastatic breast cancer (20:21)
  • Novel strategies utilizing approved and investigational ADCs (23:28)
  • Case: A woman in her early 60s with loss of HER2 expression on disease progression (31:39)
  • ADCs in combination with immunotherapy (32:51)

CME information and select publications

  continue reading

751 episodes

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