This podcast is a comprehensive guide on Peptic Ulcer Disease, from its causes to treatment. The episode describes PUD as sores in the lining of the stomach or duodenum caused by an acid imbalance. It is often caused by the bacterium Helicobacter pylori and NSAIDs. Diagnosis relies heavily on the history of pain patterns, physical examination, and various tests, with endoscopy as the gold standard in certain cases. Treatment involves stopping causative agents, suppressing acid, and managing complications.