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[Blog] Why Repeated Short-Acting Anesthetic Nerve Blocks Likely Don’t Reset Central Sensitization

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Manage episode 477256004 series 3272380
Content provided by Herman Ostrow School of Dentistry of USC Online Programs. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Herman Ostrow School of Dentistry of USC Online Programs or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

This podcast was created using NotebookLM.

This podcast explores the claim that repeated short-acting nerve blocks can reset central sensitization in chronic pain. Dr. Glenn Clark argues that this idea is unlikely due to the complex neurobiological changes involved in established chronic pain. Research suggests that while nerve blocks can prevent sensitization, they are less effective at reversing it because central sensitization involves receptor modifications, genetic changes, structural remodeling, and glial activation, which are not easily reversed by temporary input blockage.

  continue reading

24 episodes

Artwork
iconShare
 
Manage episode 477256004 series 3272380
Content provided by Herman Ostrow School of Dentistry of USC Online Programs. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Herman Ostrow School of Dentistry of USC Online Programs or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

This podcast was created using NotebookLM.

This podcast explores the claim that repeated short-acting nerve blocks can reset central sensitization in chronic pain. Dr. Glenn Clark argues that this idea is unlikely due to the complex neurobiological changes involved in established chronic pain. Research suggests that while nerve blocks can prevent sensitization, they are less effective at reversing it because central sensitization involves receptor modifications, genetic changes, structural remodeling, and glial activation, which are not easily reversed by temporary input blockage.

  continue reading

24 episodes

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