Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
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From Alcohol to Antidepressants: What Drugs Teach Us About Brain Chemistry ~ Judy Grisel
Manage episode 510155193 series 3403620
Content provided by Ilari Mäkelä. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Ilari Mäkelä or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Dopamine. Serotonin. Endorphins. We have all heard these terms. And these are not just scientific curiosities. Many of us use brain chemistry to describe our feelings and frustrations. Few are those who have never wondered if their brain chemicals are "just off balance".
So how accurate are the popular theories about these mythic molecules?
To guide us through the topic, I'm joined by Judy Grisel—an ex-addict and a world-leading neuroscientist of addiction.
We will discuss all the main elements of brain chemistry by using drugs and addictions as a window into the chemicals that flavour all of our lives. Towards the end, we also search for ways to better help those who struggle with addiction.
As always, we finish with my guest's reflection on humanity.
📖 Judy Grisel’s book is Never Enough: The Neuroscience and Experience of Addiction
Want to support the show? Join the club at Patreon.com/OnHumans.
FACT-CHECKING
No major mistakes have been found so far.
As a minor note, the SSRI study we mention in healthy volunteers primarily assessed cognitive processing (reinforcement learning/sensitivity) rather than self-reported “emotional flattening”; however, general blunting of emotional responses in healthy participants has been reported by earlier researchers.
If you spot an error in this or other episodes, please reach out on Substack or via email.
KEYWORDS
Names mentioned: Kent Berridge | Mark Lewis | Barbara Sahakian | Trevor Robbins
Terms and concepts: dopamine | wanting vs liking | serotonin (5/HT) | serotonin receptor 2A | selective serotonin uptake inhibitors SSRIs | GABA vs glutamate | endorphins | endocannabinoids | alcohol | cocaine | MDMA | psychedelics | behavioral addictions (e.g. porn) | runner's high | cannabis / THC | neurogenesis & pruning | brain plasticity | SSRIs | MDMA (SERT reversal) | emotional blunting | opponent-process theory (A→B) | addiction as disease vs learned state | meaning, motivation, recovery
92 episodes
Share
Manage episode 510155193 series 3403620
Content provided by Ilari Mäkelä. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Ilari Mäkelä or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Dopamine. Serotonin. Endorphins. We have all heard these terms. And these are not just scientific curiosities. Many of us use brain chemistry to describe our feelings and frustrations. Few are those who have never wondered if their brain chemicals are "just off balance".
So how accurate are the popular theories about these mythic molecules?
To guide us through the topic, I'm joined by Judy Grisel—an ex-addict and a world-leading neuroscientist of addiction.
We will discuss all the main elements of brain chemistry by using drugs and addictions as a window into the chemicals that flavour all of our lives. Towards the end, we also search for ways to better help those who struggle with addiction.
As always, we finish with my guest's reflection on humanity.
📖 Judy Grisel’s book is Never Enough: The Neuroscience and Experience of Addiction
Want to support the show? Join the club at Patreon.com/OnHumans.
FACT-CHECKING
No major mistakes have been found so far.
As a minor note, the SSRI study we mention in healthy volunteers primarily assessed cognitive processing (reinforcement learning/sensitivity) rather than self-reported “emotional flattening”; however, general blunting of emotional responses in healthy participants has been reported by earlier researchers.
If you spot an error in this or other episodes, please reach out on Substack or via email.
KEYWORDS
Names mentioned: Kent Berridge | Mark Lewis | Barbara Sahakian | Trevor Robbins
Terms and concepts: dopamine | wanting vs liking | serotonin (5/HT) | serotonin receptor 2A | selective serotonin uptake inhibitors SSRIs | GABA vs glutamate | endorphins | endocannabinoids | alcohol | cocaine | MDMA | psychedelics | behavioral addictions (e.g. porn) | runner's high | cannabis / THC | neurogenesis & pruning | brain plasticity | SSRIs | MDMA (SERT reversal) | emotional blunting | opponent-process theory (A→B) | addiction as disease vs learned state | meaning, motivation, recovery
92 episodes
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Similar to On Humans
Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
DNA science. Artificial intelligence. Smartphones and 3D printers. Science and technology have transformed the world we live in. But how did we get here? It wasn’t by accident. Well, sometimes it was. It was also the result of hard work, teamwork, and competition. And incredibly surprising moments. Hosted by bestselling author Steven Johnson (“How We Got To Now”), American Innovations uses immersive scenes to tell the stories of the scientists, engineers, and ordinary people behind the great ...
…
continue reading
Come dive into one of the curiously delightful conversations overheard at National Geographic’s headquarters, as we follow explorers, photographers, and scientists to the edges of our big, weird, beautiful world. Hosted by Peter Gwin and Amy Briggs.
…
continue reading
I discuss a variety of topics in both the natural and social sciences, exploring the many fascinating insights that the scientific method yields about the world around us.
…
continue reading
Interviews with Anthropologists about their New Books Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/anthropology
…
continue reading
Welcome to Curiosity Weekly from Discovery, hosted by Dr. Samantha Yammine. Once a week, we’ll bring you the latest and greatest in scientific discoveries and break down the details so that you don’t need a PhD to understand it. From neuroscience to climate tech to AI and genetics, no subject is off-limits. Join Sam as she interviews expert guests and investigates the research guiding some of the most exciting scientific breakthroughs affecting our world today. Hosted on Acast. See acast.com ...
…
continue reading
The Skeptics' Guide to the Universe is a weekly science podcast discussing the latest science news, critical thinking, bad science, conspiracies and controversies. -The Skeptics' Guide to the Universe: Your escape to reality - Produced by SGU Productions, LLC: https://www.theskepticsguide.org
…
continue reading
Help me fill in the blanks of the practice of ED Critical Care. In this podcast, we discuss all things related to the crashing, critically ill patient in the Emergency Department. Find the show notes at emcrit.org.
…
continue reading
Whether we wear a lab coat or haven't seen a test tube since grade school, science is shaping all of our lives. And that means we all have science stories to tell. Every year, we host dozens of live shows all over the country, featuring all kinds of storytellers - researchers, doctors, and engineers of course, but also patients, poets, comedians, cops, and more. Some of our stories are heartbreaking, others are hilarious, but they're all true and all very personal. Welcome to The Story Collider!
…
continue reading
Whether the topic is popcorn or particle physics, you can count on BrainStuff to explore -- and explain -- the everyday science in the world around us.
…
continue reading
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