When you hear the words Alzheimer's disease, what do you think of? The truth is, the picture most of us have of the disease is incomplete. Alzheimer's disease doesn't start when someone starts to lose their memory. It actually starts years – sometimes decades – earlier. The Rethinking Alzheimer's Disease Podcast is an engaging, narrative-style podcast miniseries for those curious or motivated to learn about Alzheimer’s disease. Perhaps you have a family member with Alzheimer’s disease, or ca ...
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continue reading
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153: Overviewing the 2025 Alzheimer's Association's Blood-Based Biomarker Guidelines
Manage episode 516914947 series 3340456
Content provided by NeurologyLive® Mind Moments®. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by NeurologyLive® Mind Moments® or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.
Following the 2025 Alzheimer's Association International Conference (AAIC), Rebecca Edelmayer, PhD, outlines the Alzheimer’s Association’s first clinical practice guidelines for using blood-based biomarkers (BBMs) in the diagnostic workup of suspected Alzheimer’s disease within specialized care. She explains the guideline mission, how tests were evaluated for accuracy, and when BBMs should serve as triage versus confirmatory tools relative to CSF and PET. Edelmayer details current scope limits (cognitively impaired patients in specialty settings), cautions against overextending to primary care or unimpaired populations, and previews the education roll-out—executive summaries, micro-learning modules, and shared decision-making resources. She closes with research priorities: stronger peer-reviewed reporting, broader validation across diverse populations and settings, and building an equitable pathway that leverages BBMs to speed accurate diagnosis and treatment access.
Looking for more Alzheimer & dementia discussion? Check out the NeurologyLive® Alzheimer & dementia clinical focus page.
Episode Breakdown:
Following the 2025 Alzheimer's Association International Conference (AAIC), Rebecca Edelmayer, PhD, outlines the Alzheimer’s Association’s first clinical practice guidelines for using blood-based biomarkers (BBMs) in the diagnostic workup of suspected Alzheimer’s disease within specialized care. She explains the guideline mission, how tests were evaluated for accuracy, and when BBMs should serve as triage versus confirmatory tools relative to CSF and PET. Edelmayer details current scope limits (cognitively impaired patients in specialty settings), cautions against overextending to primary care or unimpaired populations, and previews the education roll-out—executive summaries, micro-learning modules, and shared decision-making resources. She closes with research priorities: stronger peer-reviewed reporting, broader validation across diverse populations and settings, and building an equitable pathway that leverages BBMs to speed accurate diagnosis and treatment access.
Looking for more Alzheimer & dementia discussion? Check out the NeurologyLive® Alzheimer & dementia clinical focus page.
Episode Breakdown:
- 1:05 – Understanding the purpose and mission behind new blood-based biomarker guidelines
- 2:05 – Key recommendations and defining triage vs confirmatory blood-based biomarker use
- 3:15 – Clinical precautions and where blood-based biomarkers are appropriate today
- 5:30 – Neurology News Minute
- 7:45 – Educating clinicians on implementing BBMs in specialty care
- 10:15 – Research priorities to strengthen evidence and ensure equity
The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here:
FDA Accepts New Drug Application for Tau PET Imaging Agent MK-6240 in Alzheimer Disease
B-Cell Modulator Obexelimab Shows Pronounced Relapse Reduction in Phase 2 MoonStone Trial
Subcutaneous Efgartigimod Shows Efficacy in Phase 2 ALKIVIA, Phase 3 ADAPT SERON Trials
Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.
173 episodes
Share
Manage episode 516914947 series 3340456
Content provided by NeurologyLive® Mind Moments®. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by NeurologyLive® Mind Moments® or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.
Following the 2025 Alzheimer's Association International Conference (AAIC), Rebecca Edelmayer, PhD, outlines the Alzheimer’s Association’s first clinical practice guidelines for using blood-based biomarkers (BBMs) in the diagnostic workup of suspected Alzheimer’s disease within specialized care. She explains the guideline mission, how tests were evaluated for accuracy, and when BBMs should serve as triage versus confirmatory tools relative to CSF and PET. Edelmayer details current scope limits (cognitively impaired patients in specialty settings), cautions against overextending to primary care or unimpaired populations, and previews the education roll-out—executive summaries, micro-learning modules, and shared decision-making resources. She closes with research priorities: stronger peer-reviewed reporting, broader validation across diverse populations and settings, and building an equitable pathway that leverages BBMs to speed accurate diagnosis and treatment access.
Looking for more Alzheimer & dementia discussion? Check out the NeurologyLive® Alzheimer & dementia clinical focus page.
Episode Breakdown:
Following the 2025 Alzheimer's Association International Conference (AAIC), Rebecca Edelmayer, PhD, outlines the Alzheimer’s Association’s first clinical practice guidelines for using blood-based biomarkers (BBMs) in the diagnostic workup of suspected Alzheimer’s disease within specialized care. She explains the guideline mission, how tests were evaluated for accuracy, and when BBMs should serve as triage versus confirmatory tools relative to CSF and PET. Edelmayer details current scope limits (cognitively impaired patients in specialty settings), cautions against overextending to primary care or unimpaired populations, and previews the education roll-out—executive summaries, micro-learning modules, and shared decision-making resources. She closes with research priorities: stronger peer-reviewed reporting, broader validation across diverse populations and settings, and building an equitable pathway that leverages BBMs to speed accurate diagnosis and treatment access.
Looking for more Alzheimer & dementia discussion? Check out the NeurologyLive® Alzheimer & dementia clinical focus page.
Episode Breakdown:
- 1:05 – Understanding the purpose and mission behind new blood-based biomarker guidelines
- 2:05 – Key recommendations and defining triage vs confirmatory blood-based biomarker use
- 3:15 – Clinical precautions and where blood-based biomarkers are appropriate today
- 5:30 – Neurology News Minute
- 7:45 – Educating clinicians on implementing BBMs in specialty care
- 10:15 – Research priorities to strengthen evidence and ensure equity
The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here:
FDA Accepts New Drug Application for Tau PET Imaging Agent MK-6240 in Alzheimer Disease
B-Cell Modulator Obexelimab Shows Pronounced Relapse Reduction in Phase 2 MoonStone Trial
Subcutaneous Efgartigimod Shows Efficacy in Phase 2 ALKIVIA, Phase 3 ADAPT SERON Trials
Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.
173 episodes
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Similar to NeurologyLive® Mind Moments®
When you hear the words Alzheimer's disease, what do you think of? The truth is, the picture most of us have of the disease is incomplete. Alzheimer's disease doesn't start when someone starts to lose their memory. It actually starts years – sometimes decades – earlier. The Rethinking Alzheimer's Disease Podcast is an engaging, narrative-style podcast miniseries for those curious or motivated to learn about Alzheimer’s disease. Perhaps you have a family member with Alzheimer’s disease, or ca ...
…
continue reading
How many organs could you donate and remain alive? How many planet Earths could fit inside the Sun? How high is a giraffe's blood pressure? Why is the sea blue? To find out, Ask The Naked Scientists!
…
continue reading
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(Apple's Best of 2018) In-depth conversations with people at the top of their game. Jordan Harbinger unpacks guests' wisdom into practical nuggets you can use to impact your work, life, and relationships. Learn from leaders (Ray Dalio, Simon Sinek, Mark Cuban), entertainers (Moby, Tip "T.I." Harris, Dennis Quaid), scientists (Neil deGrasse Tyson, Bill Nye), athletes (Kobe Bryant, Dennis Rodman, Tony Hawk) and an eclectic array of fascinating minds, from art forgers and arms traffickers to sp ...
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continue reading
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…
continue reading
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continue reading
Join expert voices from Barbell Logic and others from the world of strength for resources to help you get strong for life. Get coaching options and more educational content at barbell-logic.com.
…
continue reading
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…
continue reading
How terrifying would it be to fight an unknown enemy? One you don’t recognize and didn’t see coming? What if that enemy was coming from within; a disease that even doctors couldn’t identify? Nearly half of all Americans suffer from some chronic illness and many struggle for an accurate diagnosis. Every other week on Symptomatic, host Lauren Bright Pacheco unravels the medical mystery of a patient’s baffling symptoms and explores how their lives were turned upside down in search of answers. F ...
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Join Purpose Coach Kevin Miller as he conducts deep discussions on personal evolution from his own, curious journey toward greater purpose and deeper fulfillment. Kevin researches and curates the best teachers and guides you may never find, as they are busy teaching in classes, counseling in therapy rooms, researching in labs, and coaching in offices. Go from knowledge to integration at kevinmiller.co *Over 70 million downloads, 300 expert guests, 1,500 episodes...and the journey continues o ...
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