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165: E. coli: NDM and PBP variants

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Manage episode 451357995 series 2930024
Content provided by Luis Plaza. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Luis Plaza or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

As a new microbiologist sometimes terms like beta-lactams, beta-lactamases, or penicillin-binding proteins (PBPs) can be confusing. Are you familiar with the New-Delhi metallo-beta-lactamase (NDM) and its variants? How many are there? How does this enzyme affect beta-lactam drugs?How about NDM-5? In this episode Luis is joined by Dr. Raneem Pallotta, an infectious diseases pharmacist. In the episode we go over these terms. Dr. Pallotta also talks about an NDM-producing E. coli that harbors PBP3 variants. How do these variants affect beta-lactam antibiotics? Tune in for a great episode.

Link to Dr. Pallotta's article: https://www.contagionlive.com/view/ndm-producing-e-coli-harboring-pbp-insert-variants-emerges-as-new-threat

Link to other articles:

https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-017-1012-8

https://pmc.ncbi.nlm.nih.gov/articles/PMC5527577/

https://pubmed.ncbi.nlm.nih.gov/34800710/

https://pubmed.ncbi.nlm.nih.gov/32040179/

https://pubmed.ncbi.nlm.nih.gov/25634992/

https://www.idsociety.org/practice-guideline/amr-guidance/

Questions? Feedback? Send those to [email protected]

Want to support the podcast? Here's how:

Venmo: https://venmo.com/u/letstalkmicro

Buy me a Ko-fi: https://ko-fi.com/letstalkmicro

  continue reading

219 episodes

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165: E. coli: NDM and PBP variants

Let's Talk Micro

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Manage episode 451357995 series 2930024
Content provided by Luis Plaza. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Luis Plaza or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

As a new microbiologist sometimes terms like beta-lactams, beta-lactamases, or penicillin-binding proteins (PBPs) can be confusing. Are you familiar with the New-Delhi metallo-beta-lactamase (NDM) and its variants? How many are there? How does this enzyme affect beta-lactam drugs?How about NDM-5? In this episode Luis is joined by Dr. Raneem Pallotta, an infectious diseases pharmacist. In the episode we go over these terms. Dr. Pallotta also talks about an NDM-producing E. coli that harbors PBP3 variants. How do these variants affect beta-lactam antibiotics? Tune in for a great episode.

Link to Dr. Pallotta's article: https://www.contagionlive.com/view/ndm-producing-e-coli-harboring-pbp-insert-variants-emerges-as-new-threat

Link to other articles:

https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-017-1012-8

https://pmc.ncbi.nlm.nih.gov/articles/PMC5527577/

https://pubmed.ncbi.nlm.nih.gov/34800710/

https://pubmed.ncbi.nlm.nih.gov/32040179/

https://pubmed.ncbi.nlm.nih.gov/25634992/

https://www.idsociety.org/practice-guideline/amr-guidance/

Questions? Feedback? Send those to [email protected]

Want to support the podcast? Here's how:

Venmo: https://venmo.com/u/letstalkmicro

Buy me a Ko-fi: https://ko-fi.com/letstalkmicro

  continue reading

219 episodes

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