The award-winning WIRED UK Podcast with James Temperton and the rest of the team. Listen every week for the an informed and entertaining rundown of latest technology, science, business and culture news. New episodes every Friday.
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#50 - Scaling drug discovery with quantum physics and AI - Maximilien Levesque - Aqemia
Manage episode 515849317 series 3525366
Content provided by Mathieu Chaffard. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Mathieu Chaffard or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
What's the link between quantum physics, AI, and drug discovery?
Maximilien Levesque might be the perfect person to answer.
A former theoretical physicist, he realised his research could transform drug development by fundamentally understanding how molecules interact at the atomic level.
In 2019, he co-founded Aqemia with Emmanuelle Martiano Rolland to turn that vision into reality.
Their mission is bold: to design new molecules, atom by atom, capable of binding "undruggable" therapeutic targets.
Unlike AI models that base themselves on existing compounds, Aqemia's generative engine creates novel structures, opening up a new universe of possibilities.
In this episode, Maximilien pulls back the curtain on one of TechBio's most promising startups.
With passion and clarity, he breaks down their approach to drug design, explaining how these "digitally-native" compounds go from the numeric world to real-world testing.
A conversation to understand the ins and outs of an ongoing revolution in the pharmaceutical industry!
Timeline:
- 00:00:00 - Maximilien’s background as a researcher in mathematics and quantum physics
- 00:03:46 - What drew Maximilien to drug discovery
- 00:05:43 - The link between quantum physics and drug discovery
- 00:10:27 - Aqemia’s technology to design new molecules atom-by-atom
- 00:18:36 - Aqemia’s pipeline and ongoing preclinical programs
- 00:20:27 - The difference between AI-based drug discovery and physics-based drug discovery
- 00:27:55 - Striking a balance between internal development programs and external collaborations
- 00:32:35 - Aqemia’s approach to talent recruitment at the interface of biology, mathematics, and computer science
- 00:34:23 - Maximilien’s wish to enter clinical trials in 2026
What we also talked about with Maximilien:
- HIMSS Europe
- École Normale Supérieur (ENS)
- Centre National de la Recherche Scientifique (CNRS)
- Commissariat à l’Énergie Atomique et aux Énergies Alternatives (CEA)
- Ornstein-Zernike equation
- American Institute of Physics
- Sanofi
- Institut Gustave Roussy
We cited with Maximilien some of the past episodes of the series:
- #40 - Cracking biology through AI - JP Vert - Owkin
- #33 - Building the next TechBio venture - Mati Gill - AION Labs
- #13 - Catalyzing drug discovery using organ-on-a-chip models - Bas Trietsch - Mimetas
You can learn more about Maximilien’s publications here and prompt ChatGPT, as he suggested, to find out more about quantum physics, AI, and their applications in the field of drug discovery!
You can reach out to Maximilien via LinkedIn and follow Aqemia’s activities on their website and LinkedIn page!
✉️ If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email!
⭐️ And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms!
🙏 You can also support my work by doing a PayPal donation @ImpulsePodcast!
👍 Lastly, don’t forget to follow our activities on LinkedIn and our website!
101 episodes
Share
Manage episode 515849317 series 3525366
Content provided by Mathieu Chaffard. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Mathieu Chaffard or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
What's the link between quantum physics, AI, and drug discovery?
Maximilien Levesque might be the perfect person to answer.
A former theoretical physicist, he realised his research could transform drug development by fundamentally understanding how molecules interact at the atomic level.
In 2019, he co-founded Aqemia with Emmanuelle Martiano Rolland to turn that vision into reality.
Their mission is bold: to design new molecules, atom by atom, capable of binding "undruggable" therapeutic targets.
Unlike AI models that base themselves on existing compounds, Aqemia's generative engine creates novel structures, opening up a new universe of possibilities.
In this episode, Maximilien pulls back the curtain on one of TechBio's most promising startups.
With passion and clarity, he breaks down their approach to drug design, explaining how these "digitally-native" compounds go from the numeric world to real-world testing.
A conversation to understand the ins and outs of an ongoing revolution in the pharmaceutical industry!
Timeline:
- 00:00:00 - Maximilien’s background as a researcher in mathematics and quantum physics
- 00:03:46 - What drew Maximilien to drug discovery
- 00:05:43 - The link between quantum physics and drug discovery
- 00:10:27 - Aqemia’s technology to design new molecules atom-by-atom
- 00:18:36 - Aqemia’s pipeline and ongoing preclinical programs
- 00:20:27 - The difference between AI-based drug discovery and physics-based drug discovery
- 00:27:55 - Striking a balance between internal development programs and external collaborations
- 00:32:35 - Aqemia’s approach to talent recruitment at the interface of biology, mathematics, and computer science
- 00:34:23 - Maximilien’s wish to enter clinical trials in 2026
What we also talked about with Maximilien:
- HIMSS Europe
- École Normale Supérieur (ENS)
- Centre National de la Recherche Scientifique (CNRS)
- Commissariat à l’Énergie Atomique et aux Énergies Alternatives (CEA)
- Ornstein-Zernike equation
- American Institute of Physics
- Sanofi
- Institut Gustave Roussy
We cited with Maximilien some of the past episodes of the series:
- #40 - Cracking biology through AI - JP Vert - Owkin
- #33 - Building the next TechBio venture - Mati Gill - AION Labs
- #13 - Catalyzing drug discovery using organ-on-a-chip models - Bas Trietsch - Mimetas
You can learn more about Maximilien’s publications here and prompt ChatGPT, as he suggested, to find out more about quantum physics, AI, and their applications in the field of drug discovery!
You can reach out to Maximilien via LinkedIn and follow Aqemia’s activities on their website and LinkedIn page!
✉️ If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email!
⭐️ And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms!
🙏 You can also support my work by doing a PayPal donation @ImpulsePodcast!
👍 Lastly, don’t forget to follow our activities on LinkedIn and our website!
101 episodes
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Similar to Impulse - Meeting Healthcare Pioneers
The award-winning WIRED UK Podcast with James Temperton and the rest of the team. Listen every week for the an informed and entertaining rundown of latest technology, science, business and culture news. New episodes every Friday.
…
continue reading
The American healthcare system is one of the most innovative in the world. But it’s also riddled with complex challenges, such as access to affordable medications, inefficiency and administrative burdens, and communication barriers between providers. There’s clearly a better way—and at Surescripts, we have a unique sightline into what that may be. In this series, host Melanie Marcus, Chief Marketing Officer of Surescripts, sits down with today’s most inspiring and innovative leaders in healt ...
…
continue reading
The power of Data is undeniable. And unharnessed - it's nothing but chaos. Making data your ally. Using it to lead with confidence and clarity. Host Jess Carter is solving problems in real-time to reveal what's possible. Helping communities and people thrive. This is Data Driven Leadership, a show brought to you by Resultant.
…
continue reading
BBC Radio 5 live’s award winning gaming podcast, discussing the world of video games and games culture.
…
continue reading
The director’s commentary track for Daring Fireball. Long digressions on Apple, technology, design, movies, and more.
…
continue reading
Investor Shayle Kann is asking big questions about how to decarbonize the planet: How cheap can clean energy get? Will artificial intelligence speed up climate solutions? Where is the smart money going into climate technologies? Every week on Catalyst, Shayle explains the world of climate tech with prominent experts, investors, researchers, and executives. Produced by Latitude Media.
…
continue reading
When you hear the words Alzheimer's disease, what do you think of? The truth is, the picture most of us have of the disease is incomplete. Alzheimer's disease doesn't start when someone starts to lose their memory. It actually starts years – sometimes decades – earlier. The Rethinking Alzheimer's Disease Podcast is an engaging, narrative-style podcast miniseries for those curious or motivated to learn about Alzheimer’s disease. Perhaps you have a family member with Alzheimer’s disease, or ca ...
…
continue reading
A top podcast for healthcare leaders, with over one million downloads, Radio Advisory is your weekly download on how to untangle the industry's most pressing challenges to help leaders like you make the best business decisions for your organization. From unpacking major trends in care delivery—like site-of-care shifts and the rise of high-cost drugs—to demystifying stakeholder dynamics, to shining a spotlight on priorities that may get overlooked, we're here to help. Our hosts and seasoned r ...
…
continue reading
Stay current on JavaScript, Node, and Front-End development. Learn from experts in programming, careers, and technology every week. Become a supporter of this podcast: https://www.spreaker.com/podcast/javascript-jabber--6102064/support.
…
continue reading
WSJ’s Bold Names brings you conversations with the leaders of the bold-named companies featured in the pages of The Wall Street Journal. Hosts Tim Higgins and Christopher Mims speak to CEOs and business leaders in interviews that challenge conventional wisdom and take you inside the decisions being made in the C-suite and beyond.
…
continue reading
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Go offline with the Player FM app!
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