In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the complex world of Lipid Transfer Protein (LTP) allergy — a powerful plant food allergen that can cause severe and unexpected allergic reactions.

Join us as we unpack how LTP allergy differs from pollen-related food syndromes, why it’s often seen in Mediterranean populations, and what clinicians, families, and patients need to know about cross-reactivity, diagnosis, and management.

You’ll learn about:

🌿 What LTPs are and how they trigger allergy

🍑 Common culprit foods — from peach to peanut

⚕️ The role of component-resolved diagnostics in identifying LTP sensitisation

🧠 Practical tips on prevention, patient education, and emergency planning

Whether you’re a paediatrician, allergy trainee, dietitian, or an interested parent, this episode offers a clear, evidence-based overview of one of the most under-recognised causes of severe food allergy.

Sources:

1. Marinho, S., Frleta-Gilchrist, M., Hunter, H., Murgasova, D., Patel, N., Till, S. and Skypala, I. J. (2025) Diagnosis and Management of Lipid Transfer Protein Allergy—A BSACI Clinical Practice Statement. Clinical and Experimental Allergy, 55(4), pp. 307–318. doi: 10.1111/cea.70022.
2. Olivieri, B. and Skypala, I. J. (2024) The Diagnosis of Allergy to Lipid Transfer Proteins. Current Allergy and Asthma Reports, 24, pp. 509–518. doi: 10.1007/s11882-024-01164-8.
3. Olivieri, B., Scadding, G. and Skypala, I. J. (2025) The diagnosis of lipid transfer protein allergy—Discriminating between sensitisation and allergy. Clinical and Translational Allergy, e70065. doi: 10.1002/clt2.70065.

Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.

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