Bitcoin pioneer Charlie Shrem peels back the layers on the lives and backgrounds of the world's most impactful innovators. Centering around intimate narratives, Shrem uncovers a detailed, previously unspoken story of the genesis and evolution of bitcoin, cryptocurrency, artificial intelligence, and the web3 movements. Join Shrem as he journeys through the uncharted territories of tech revolutions, revealing the human side of the stories that shaped the digital world we live in today.
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Content provided by ARK Invest. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by ARK Invest or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
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Curing Hair Loss With Sean McClain
Manage episode 519293181 series 1532639
Content provided by ARK Invest. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by ARK Invest or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
In this episode, ARK’s Cathie Wood and Brett Winton sit down with Sean McClain, Founder and CEO of AbSci, to explore how generative AI is reshaping drug discovery, development timelines, and clinical costs. Sean walks through real-world examples of AI-designed antibodies—such as AbSci’s breakthrough HIV antibody and a regenerative treatment for hair loss—and explains how these platforms are helping unlock previously “undruggable” biology.
They discuss AbSci’s Phase 2-ready hair growth antibody (BS201), the company’s partnerships with Caltech and AMD, and why the FDA’s evolving embrace of AI could accelerate the end of animal testing. The conversation closes with a forward-looking discussion on the role of regenerative medicine in longevity—and why AI drug discovery might just pull biotech out of its multi-year bear market.
Key Points From This Episode:
- (00:00:00) How AbSci uses generative AI to design antibodies from scratch
- (00:02:42) HIV, ion channels, and the promise of targeting "undruggable" biology
- (00:06:28) AbSci’s BS201 drug for hair regrowth: mechanism, speed, and cost advantages
- (00:13:20) Clinical timeline: From concept to Phase 2 readout in 3.5 years
- (00:15:34) Bringing costs down: $100–150M vs. the industry average of $2.4B
- (00:17:36) Why AI enables “keys designed for specific locks” in drug targeting
- (00:22:58) What AbSci’s models are trained on—and how prompts work in drug inference
- (00:25:32) The future of clinical testing: AI replacing animal models
- (00:36:43) Sarcopenia, strength loss, and regenerative approaches to aging
- (00:48:10) BS201 as a long-acting pulse therapy—and how it compares to transplants
395 episodes
Share
Manage episode 519293181 series 1532639
Content provided by ARK Invest. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by ARK Invest or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
In this episode, ARK’s Cathie Wood and Brett Winton sit down with Sean McClain, Founder and CEO of AbSci, to explore how generative AI is reshaping drug discovery, development timelines, and clinical costs. Sean walks through real-world examples of AI-designed antibodies—such as AbSci’s breakthrough HIV antibody and a regenerative treatment for hair loss—and explains how these platforms are helping unlock previously “undruggable” biology.
They discuss AbSci’s Phase 2-ready hair growth antibody (BS201), the company’s partnerships with Caltech and AMD, and why the FDA’s evolving embrace of AI could accelerate the end of animal testing. The conversation closes with a forward-looking discussion on the role of regenerative medicine in longevity—and why AI drug discovery might just pull biotech out of its multi-year bear market.
Key Points From This Episode:
- (00:00:00) How AbSci uses generative AI to design antibodies from scratch
- (00:02:42) HIV, ion channels, and the promise of targeting "undruggable" biology
- (00:06:28) AbSci’s BS201 drug for hair regrowth: mechanism, speed, and cost advantages
- (00:13:20) Clinical timeline: From concept to Phase 2 readout in 3.5 years
- (00:15:34) Bringing costs down: $100–150M vs. the industry average of $2.4B
- (00:17:36) Why AI enables “keys designed for specific locks” in drug targeting
- (00:22:58) What AbSci’s models are trained on—and how prompts work in drug inference
- (00:25:32) The future of clinical testing: AI replacing animal models
- (00:36:43) Sarcopenia, strength loss, and regenerative approaches to aging
- (00:48:10) BS201 as a long-acting pulse therapy—and how it compares to transplants
395 episodes
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Similar to FYI - For Your Innovation
Bitcoin pioneer Charlie Shrem peels back the layers on the lives and backgrounds of the world's most impactful innovators. Centering around intimate narratives, Shrem uncovers a detailed, previously unspoken story of the genesis and evolution of bitcoin, cryptocurrency, artificial intelligence, and the web3 movements. Join Shrem as he journeys through the uncharted territories of tech revolutions, revealing the human side of the stories that shaped the digital world we live in today.
…
continue reading
The show that helps you maximize your wealth by turning complex financial situations into actionable advice. On Your Money. Your Mission., we answer the questions you’ve been asking about -- financial planning, investing, retirement and everything in between. Whether you’re navigating the complexities of the market or looking for the best ways to save or spend your money, tune in to hear from experienced financial advisors with JFG. Walk away from each episode with savvy tips and financial t ...
…
continue reading
Tim Reid (AKA Timbo) interviews the most innovative founders in the world of small business. In this award winning podcast business owners share where their original business idea came from, how they got it to market and the strategies they used that led to their business’s unprecedented growth. Tim Reid's curiosity for what makes business owners tick and his passion for small business success means that every episode is chock full of marketing gold that will help you build that beautiful bu ...
…
continue reading
Best Business Podcast (Gold), British Podcast Awards 2023 How do you build a fully electric motorcycle with no compromises on performance? How can we truly experience what the virtual world feels like? What does it take to design the first commercially available flying car? And how do you build a lightsaber? These are some of the questions this podcast answers as we share the moments where digital transforms physical, and meet the brilliant minds behind some of the most innovative products a ...
…
continue reading
Big tech is transforming every aspect of our world. But how, and at what cost? This season of Land of the Giants – The Disney Dilemma – focuses on Disney’s ability to weather the ups and downs of the business cycle and changing tastes and explores what has kept it successful for over 100 years. The entertainment giant has leveraged nostalgia and its intellectual property to build a beloved brand, but after an acquisition spree that included Marvel, Lucasfilm, and 20th Century Fox, can it sus ...
…
continue reading
Where startup founders raise millions and listeners can invest. Host Josh Muccio takes listeners behind closed-doors and into the room where deals are made. Part of the Vox Media Podcast Network.
…
continue reading
It didn’t all change in March 2020. Not really. The UK high street has been in the throes of a gradual revolution for decades. From the rise of ecommerce, to the birth of mobile, social commerce, and a growing emphasis on experience, change has been underway for a while. In fact for many, the pandemic has acted as a wake-up call. Digital transformation was no longer a ‘nice to have’ but a matter of survival. Necessity sparked innovation and customers are enjoying more flexibility and conveni ...
…
continue reading
Capitalmind looks at stocks, bonds, funds and the macro to bring you their view on the Indian financial markets. We discuss all things related to investing at our focussed podcast that keeps it simple. For more, go to capitalmind.in and to invest with us, visit capitalmindwealth.com
…
continue reading
Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
Alessandro Bogliari, CEO and Co-Founder of The Influencer Marketing Factory, a global influencer marketing agency, talks with great guests about influencer marketing, social media, the creator economy, social commerce and much more.
…
continue reading
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Go offline with the Player FM app!
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