The Weston A. Price Foundation's Wise Traditions podcast is for those who seek optimal health based on traditional wisdom. We believe that vibrant health cannot be cultivated in a lab, engineered through modern technology or found through "improving" nature. On the contrary, "life in all its fullness is mother nature obeyed," as Dr. Weston Price put it. We can learn from healthy societies of the past how to live healthier lives now. The Foundation's podcast is an invitation to follow traditi ...
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Obesity Drives Alzheimer's Through Fat Vesicles and Leptin
MP3•Episode home
Manage episode 522248327 series 1582679
Content provided by Briana Mercola and Dr. Mercola. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Briana Mercola and Dr. Mercola or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
- Obesity increases Alzheimer's risk by altering how fat-derived vesicles communicate with the brain, causing amyloid proteins to misfold and form toxic plaques that damage neurons and impair cognition
- Specific lipids from obese individuals, including sphingolipids and ceramides, create oxidative stress in brain cells, reduce mitochondrial energy production, and accelerate the formation of sticky amyloid aggregates
- Excessive fat consumption promotes Alzheimer's development, though balanced, controlled intake at lower concentrations helps inhibit amyloid aggregation and reduce disease risk
- Leptin resistance from obesity prevents this protective hormone from reaching the brain, disabling the cleanup process that normally breaks down amyloid proteins while worsening inflammation and cognitive decline
- Cellular health restoration requires eliminating four key factors — excess linoleic acid from vegetable oils, endocrine-disrupting chemicals, electromagnetic fields, and endotoxins in the gut
1059 episodes
MP3•Episode home
Manage episode 522248327 series 1582679
Content provided by Briana Mercola and Dr. Mercola. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Briana Mercola and Dr. Mercola or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
- Obesity increases Alzheimer's risk by altering how fat-derived vesicles communicate with the brain, causing amyloid proteins to misfold and form toxic plaques that damage neurons and impair cognition
- Specific lipids from obese individuals, including sphingolipids and ceramides, create oxidative stress in brain cells, reduce mitochondrial energy production, and accelerate the formation of sticky amyloid aggregates
- Excessive fat consumption promotes Alzheimer's development, though balanced, controlled intake at lower concentrations helps inhibit amyloid aggregation and reduce disease risk
- Leptin resistance from obesity prevents this protective hormone from reaching the brain, disabling the cleanup process that normally breaks down amyloid proteins while worsening inflammation and cognitive decline
- Cellular health restoration requires eliminating four key factors — excess linoleic acid from vegetable oils, endocrine-disrupting chemicals, electromagnetic fields, and endotoxins in the gut
1059 episodes
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