Starting Strength is the bestselling book on the most fundamental and effective approach to strength training ever written. Mark Rippetoe hosts Starting Strength Radio where he discusses topics of interest, primarily to him, but perhaps also to you.
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How Chronic Stress Increases Risk of Depression
MP3•Episode home
Manage episode 518261410 series 1582679
Content provided by Briana Mercola and Dr. Mercola. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Briana Mercola and Dr. Mercola or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
- Chronic stress triggers a neutrophil invasion into brain-protective layers, driving depression-like behaviors through immune activation rather than just hormonal changes
- Stress-induced immune signals hijack brain reward circuits, reducing dopamine and shifting neural activity toward threat detection over pleasure-seeking behaviors
- Prolonged stress damages brain mitochondria, reducing cellular energy production while creating an inflammatory feedback loop that worsens mood and cognitive function
- Interferon pathways and inflammatory cytokines like IL-6 cross into the brain, directly altering neuron firing patterns in emotional regulation centers
- Natural interventions including healthy carbohydrates, regular exercise, positive thinking, creativity, and physical touch help counter stress-induced immune activation and protect mental health
1016 episodes
MP3•Episode home
Manage episode 518261410 series 1582679
Content provided by Briana Mercola and Dr. Mercola. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Briana Mercola and Dr. Mercola or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
- Chronic stress triggers a neutrophil invasion into brain-protective layers, driving depression-like behaviors through immune activation rather than just hormonal changes
- Stress-induced immune signals hijack brain reward circuits, reducing dopamine and shifting neural activity toward threat detection over pleasure-seeking behaviors
- Prolonged stress damages brain mitochondria, reducing cellular energy production while creating an inflammatory feedback loop that worsens mood and cognitive function
- Interferon pathways and inflammatory cytokines like IL-6 cross into the brain, directly altering neuron firing patterns in emotional regulation centers
- Natural interventions including healthy carbohydrates, regular exercise, positive thinking, creativity, and physical touch help counter stress-induced immune activation and protect mental health
1016 episodes
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