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How Chronic Stress Increases Risk of Depression

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Manage episode 518261410 series 1582679
Content provided by Briana Mercola and Dr. Mercola. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Briana Mercola and Dr. Mercola or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
  • Chronic stress triggers a neutrophil invasion into brain-protective layers, driving depression-like behaviors through immune activation rather than just hormonal changes
  • Stress-induced immune signals hijack brain reward circuits, reducing dopamine and shifting neural activity toward threat detection over pleasure-seeking behaviors
  • Prolonged stress damages brain mitochondria, reducing cellular energy production while creating an inflammatory feedback loop that worsens mood and cognitive function
  • Interferon pathways and inflammatory cytokines like IL-6 cross into the brain, directly altering neuron firing patterns in emotional regulation centers
  • Natural interventions including healthy carbohydrates, regular exercise, positive thinking, creativity, and physical touch help counter stress-induced immune activation and protect mental health
  continue reading

1016 episodes

Artwork
iconShare
 
Manage episode 518261410 series 1582679
Content provided by Briana Mercola and Dr. Mercola. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Briana Mercola and Dr. Mercola or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
  • Chronic stress triggers a neutrophil invasion into brain-protective layers, driving depression-like behaviors through immune activation rather than just hormonal changes
  • Stress-induced immune signals hijack brain reward circuits, reducing dopamine and shifting neural activity toward threat detection over pleasure-seeking behaviors
  • Prolonged stress damages brain mitochondria, reducing cellular energy production while creating an inflammatory feedback loop that worsens mood and cognitive function
  • Interferon pathways and inflammatory cytokines like IL-6 cross into the brain, directly altering neuron firing patterns in emotional regulation centers
  • Natural interventions including healthy carbohydrates, regular exercise, positive thinking, creativity, and physical touch help counter stress-induced immune activation and protect mental health
  continue reading

1016 episodes

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