How many organs could you donate and remain alive? How many planet Earths could fit inside the Sun? How high is a giraffe's blood pressure? Why is the sea blue? To find out, Ask The Naked Scientists!
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Content provided by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
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170: Inside SITC 2025: How Multiplex IF Is Changing Cancer Care
Manage episode 518208440 series 3404634
Content provided by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Can spatial biology and multiplex immunofluorescence truly transform how we understand cancer?
I went live from the Society for Immunotherapy of Cancer (SITC) 2025 — the 40th Anniversary Meeting to explore how spatial biology, multiplex IF, and digital pathology are coming together to redefine cancer diagnostics, research, and precision medicine.
This session kicked off a weekend of cutting-edge discussions with leaders from Hamamatsu (Booth 415) and Biocare Medical (Booth 717) — two companies helping laboratories around the world embrace digital transformation and spatial imaging in oncology.
🧠 Episode Highlights & Key Moments
0:00 — Introduction
I set the stage live from SITC 2025, explaining the goal of this series: to connect the science of multiplex imaging and spatial analysis with the practical needs of today’s cancer pathologists and researchers.
~1:00 — What Is Multiplex Immunofluorescence (IF)?
I explain how multiplex IF enables simultaneous detection of multiple biomarkers and immune cell types within a single tumor sample — giving us an unprecedented look at the tumor microenvironment and how cells interact.
~2:30 — The Spatial Biology Revolution
We talk about spatial biology as the “next frontier” beyond traditional histopathology — visualizing not just what is on the slide, but where it happens.
~5:00 — Digital Pathology & AI Readiness
I discuss the importance of digital pathology systems for slide digitization and how AI-powered software is now helping identify biomarkers, quantify expression, and accelerate immunotherapy research.
~7:30 — Featured Booths at SITC 2025
- Hamamatsu (Booth 415): High-end slide scanners and digital imaging solutions empowering pathology labs toward digital readiness.
- Biocare Medical (Booth 717): Showcasing the ONCORE Pro X — an open slide stainer that automates multiplex IF, IHC, FISH, and ISH protocols, plus smart software for optimizing complex staining processes.
~9:00 — Real-World Impact
We walk through clinical case examples where multiplex IF data guides immunotherapy decisions — helping clinicians stratify patients and tailor treatments more precisely.
~12:00 — Getting Started
I share practical advice for researchers ready to adopt spatial biology or digital pathology, from workflow design to validation and staff training.
~15:00 — Audience Q&A
Live questions from the audience on implementation, data integration, and scaling multiplex workflows across research and clinical environments.
~20:00 — Future Directions
We look ahead to how machine learning and spatial data integration will shape the next decade of immuno-oncology, including new SITC workshops on AI-driven tissue profiling.
~24:00 — Wrap-Up & Takeaways
Key message: spatial biology is not just a trend — it’s the next layer of precision medicine. I invite everyone to visit Hamamatsu (Booth 415) and Biocare (Booth 717) and to stay tuned for the next livestream focused on multiplex IF in clinical settings.
Resources Mentioned
🔹 Hamamatsu Photonics (Booth 415)
High-performance digital slide scanners and imaging systems.
🌐 hamamatsu.com
🔹 Biocare Medical (Booth 717)
ONCORE Pro X — Open sli
170 episodes
Share
Manage episode 518208440 series 3404634
Content provided by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.
Can spatial biology and multiplex immunofluorescence truly transform how we understand cancer?
I went live from the Society for Immunotherapy of Cancer (SITC) 2025 — the 40th Anniversary Meeting to explore how spatial biology, multiplex IF, and digital pathology are coming together to redefine cancer diagnostics, research, and precision medicine.
This session kicked off a weekend of cutting-edge discussions with leaders from Hamamatsu (Booth 415) and Biocare Medical (Booth 717) — two companies helping laboratories around the world embrace digital transformation and spatial imaging in oncology.
🧠 Episode Highlights & Key Moments
0:00 — Introduction
I set the stage live from SITC 2025, explaining the goal of this series: to connect the science of multiplex imaging and spatial analysis with the practical needs of today’s cancer pathologists and researchers.
~1:00 — What Is Multiplex Immunofluorescence (IF)?
I explain how multiplex IF enables simultaneous detection of multiple biomarkers and immune cell types within a single tumor sample — giving us an unprecedented look at the tumor microenvironment and how cells interact.
~2:30 — The Spatial Biology Revolution
We talk about spatial biology as the “next frontier” beyond traditional histopathology — visualizing not just what is on the slide, but where it happens.
~5:00 — Digital Pathology & AI Readiness
I discuss the importance of digital pathology systems for slide digitization and how AI-powered software is now helping identify biomarkers, quantify expression, and accelerate immunotherapy research.
~7:30 — Featured Booths at SITC 2025
- Hamamatsu (Booth 415): High-end slide scanners and digital imaging solutions empowering pathology labs toward digital readiness.
- Biocare Medical (Booth 717): Showcasing the ONCORE Pro X — an open slide stainer that automates multiplex IF, IHC, FISH, and ISH protocols, plus smart software for optimizing complex staining processes.
~9:00 — Real-World Impact
We walk through clinical case examples where multiplex IF data guides immunotherapy decisions — helping clinicians stratify patients and tailor treatments more precisely.
~12:00 — Getting Started
I share practical advice for researchers ready to adopt spatial biology or digital pathology, from workflow design to validation and staff training.
~15:00 — Audience Q&A
Live questions from the audience on implementation, data integration, and scaling multiplex workflows across research and clinical environments.
~20:00 — Future Directions
We look ahead to how machine learning and spatial data integration will shape the next decade of immuno-oncology, including new SITC workshops on AI-driven tissue profiling.
~24:00 — Wrap-Up & Takeaways
Key message: spatial biology is not just a trend — it’s the next layer of precision medicine. I invite everyone to visit Hamamatsu (Booth 415) and Biocare (Booth 717) and to stay tuned for the next livestream focused on multiplex IF in clinical settings.
Resources Mentioned
🔹 Hamamatsu Photonics (Booth 415)
High-performance digital slide scanners and imaging systems.
🌐 hamamatsu.com
🔹 Biocare Medical (Booth 717)
ONCORE Pro X — Open sli
170 episodes
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Similar to Digital Pathology Podcast
How many organs could you donate and remain alive? How many planet Earths could fit inside the Sun? How high is a giraffe's blood pressure? Why is the sea blue? To find out, Ask The Naked Scientists!
…
continue reading
When you hear the words Alzheimer's disease, what do you think of? The truth is, the picture most of us have of the disease is incomplete. Alzheimer's disease doesn't start when someone starts to lose their memory. It actually starts years – sometimes decades – earlier. The Rethinking Alzheimer's Disease Podcast is an engaging, narrative-style podcast miniseries for those curious or motivated to learn about Alzheimer’s disease. Perhaps you have a family member with Alzheimer’s disease, or ca ...
…
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Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
DNA science. Artificial intelligence. Smartphones and 3D printers. Science and technology have transformed the world we live in. But how did we get here? It wasn’t by accident. Well, sometimes it was. It was also the result of hard work, teamwork, and competition. And incredibly surprising moments. Hosted by bestselling author Steven Johnson (“How We Got To Now”), American Innovations uses immersive scenes to tell the stories of the scientists, engineers, and ordinary people behind the great ...
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Help me fill in the blanks of the practice of ED Critical Care. In this podcast, we discuss all things related to the crashing, critically ill patient in the Emergency Department. Find the show notes at emcrit.org.
…
continue reading
Whether the topic is popcorn or particle physics, you can count on BrainStuff to explore -- and explain -- the everyday science in the world around us.
…
continue reading
Emergency Medicine Cases – Where the Experts Keep You in the Know. For show notes, quizzes, videos and more learning tools please visit emergencymedicinecases.com
…
continue reading
A top podcast for healthcare leaders, with over one million downloads, Radio Advisory is your weekly download on how to untangle the industry's most pressing challenges to help leaders like you make the best business decisions for your organization. From unpacking major trends in care delivery—like site-of-care shifts and the rise of high-cost drugs—to demystifying stakeholder dynamics, to shining a spotlight on priorities that may get overlooked, we're here to help. Our hosts and seasoned r ...
…
continue reading
I discuss a variety of topics in both the natural and social sciences, exploring the many fascinating insights that the scientific method yields about the world around us.
…
continue reading
The award-winning WIRED UK Podcast with James Temperton and the rest of the team. Listen every week for the an informed and entertaining rundown of latest technology, science, business and culture news. New episodes every Friday.
…
continue reading
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Go offline with the Player FM app!
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