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The Mitochondrial “Vitamin” from Interstellar Dust

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Manage episode 517961393 series 3635277
Content provided by Dr. William Wallace. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr. William Wallace or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

There’s a molecule that’s been tentatively identified in the same interstellar material that forms stars and planets, yet it also shapes growth, metabolism, and cognition here on Earth. In several mammalian species,Its absence causes deficiency and it's repletion, resolution; and no, it’s not a vitamin, but should it be?

Its chemistry is analogous to the combination of vitamin B2, vitamin B6 vitamin C, and its role in evolution may trace back to the very beginning of biology.

00:00 – From Interstellar Dust to Human Biology
01:06 – Discovery: A New Redox Co-Factor
01:44 – Biological Role: Deficiency, Growth, and Evolution
02:41 – Mechanisms: NAD⁺ Regeneration and Mitochondrial Signaling
03:11 – Human Evidence: Cognitive and Metabolic Effects
04:41 – Chemistry & Safety: Potency and Tolerability
06:55 – Conclusion

https://pmc.ncbi.nlm.nih.gov/articles/PMC8533503/

  continue reading

Chapters

1. A Molecule On The Edge Of Life (00:00:00)

2. The 1964 Mystery And PQQ’s Discovery (00:01:15)

3. Deficiency Signals Across Species (00:02:14)

4. Human Trials And Mitochondrial Benefits (00:03:10)

5. Redox Network, NAD Plus, And Safety (00:04:23)

6. From Stardust To Cells (00:07:23)

66 episodes

Artwork
iconShare
 
Manage episode 517961393 series 3635277
Content provided by Dr. William Wallace. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr. William Wallace or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

There’s a molecule that’s been tentatively identified in the same interstellar material that forms stars and planets, yet it also shapes growth, metabolism, and cognition here on Earth. In several mammalian species,Its absence causes deficiency and it's repletion, resolution; and no, it’s not a vitamin, but should it be?

Its chemistry is analogous to the combination of vitamin B2, vitamin B6 vitamin C, and its role in evolution may trace back to the very beginning of biology.

00:00 – From Interstellar Dust to Human Biology
01:06 – Discovery: A New Redox Co-Factor
01:44 – Biological Role: Deficiency, Growth, and Evolution
02:41 – Mechanisms: NAD⁺ Regeneration and Mitochondrial Signaling
03:11 – Human Evidence: Cognitive and Metabolic Effects
04:41 – Chemistry & Safety: Potency and Tolerability
06:55 – Conclusion

https://pmc.ncbi.nlm.nih.gov/articles/PMC8533503/

  continue reading

Chapters

1. A Molecule On The Edge Of Life (00:00:00)

2. The 1964 Mystery And PQQ’s Discovery (00:01:15)

3. Deficiency Signals Across Species (00:02:14)

4. Human Trials And Mitochondrial Benefits (00:03:10)

5. Redox Network, NAD Plus, And Safety (00:04:23)

6. From Stardust To Cells (00:07:23)

66 episodes

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