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Magnesium: The ‘Best’ Form Isn’t What You Think Part 1.

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Manage episode 521161574 series 3635277
Content provided by Dr. William Wallace. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr. William Wallace or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

Magnesium supplements are marketed like different compounds with different biological targets - i.e., “for sleep,” “for the brain,” “for stress,” “for energy.” But the foundation of these claims depends on chemistry: how magnesium salts dissolve, how they release Mg²⁺ in the gut, and how much actually reaches circulation.

Part 1 breaks down the first half of the magnesium story: why magnesium must be paired with a counter-ion, how dissolution determines real absorption, and what modern data show when common salts like citrate, glycinate, and oxide are compared head-to-head.

The goal: separating marketing myths from measurable differences in solubility, acute bioavailability, and baseline magnesium status

00:00 Introduction to Magnesium Forms

00:30 Magnesium's Chemical Nature

01:11 Absorption Differences Among Magnesium Forms

01:35 Clinical Studies on Magnesium Absorption

04:24 Magnesium in Animal Studies

06:05 Human Studies on Magnesium

08:47 Conclusion and Preview of Part Two

  • Doi: 10.1186/s40795-016-0121-3
  • PMID: 11550076
  • PMID: 31330811
  • PMID: 39252819
  • PMID: 26519439
  • PMID: 34111673
  • PMID: 23853635
  • doi: 10.3390/nu9050429
  • PMID: 39009081
  continue reading

Chapters

1. Why Magnesium Comes In Many Forms (00:00:00)

2. Dissolution Drives Absorption (00:01:00)

3. Citrate Versus Oxide Head To Head (00:02:35)

4. Product Variability And Label Limits (00:04:00)

5. Beyond Absorption: Tissue Questions (00:05:00)

6. Rodent Data On Brain Magnesium (00:06:10)

7. Human Evidence And Its Limits (00:07:30)

8. L‑Threonate Findings And Context (00:08:20)

68 episodes

Artwork
iconShare
 
Manage episode 521161574 series 3635277
Content provided by Dr. William Wallace. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr. William Wallace or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://podcastplayer.com/legal.

Magnesium supplements are marketed like different compounds with different biological targets - i.e., “for sleep,” “for the brain,” “for stress,” “for energy.” But the foundation of these claims depends on chemistry: how magnesium salts dissolve, how they release Mg²⁺ in the gut, and how much actually reaches circulation.

Part 1 breaks down the first half of the magnesium story: why magnesium must be paired with a counter-ion, how dissolution determines real absorption, and what modern data show when common salts like citrate, glycinate, and oxide are compared head-to-head.

The goal: separating marketing myths from measurable differences in solubility, acute bioavailability, and baseline magnesium status

00:00 Introduction to Magnesium Forms

00:30 Magnesium's Chemical Nature

01:11 Absorption Differences Among Magnesium Forms

01:35 Clinical Studies on Magnesium Absorption

04:24 Magnesium in Animal Studies

06:05 Human Studies on Magnesium

08:47 Conclusion and Preview of Part Two

  • Doi: 10.1186/s40795-016-0121-3
  • PMID: 11550076
  • PMID: 31330811
  • PMID: 39252819
  • PMID: 26519439
  • PMID: 34111673
  • PMID: 23853635
  • doi: 10.3390/nu9050429
  • PMID: 39009081
  continue reading

Chapters

1. Why Magnesium Comes In Many Forms (00:00:00)

2. Dissolution Drives Absorption (00:01:00)

3. Citrate Versus Oxide Head To Head (00:02:35)

4. Product Variability And Label Limits (00:04:00)

5. Beyond Absorption: Tissue Questions (00:05:00)

6. Rodent Data On Brain Magnesium (00:06:10)

7. Human Evidence And Its Limits (00:07:30)

8. L‑Threonate Findings And Context (00:08:20)

68 episodes

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